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PRJNA207719: Tissue specific transcriptome profiling

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Results for mycb

Z-value: 1.02

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Transcription factors associated with mycb

Gene Symbol Gene ID Gene Info
mycb
ENSDARG00000007241 MYC proto-oncogene, bHLH transcription factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycbdr11_v1_chr2_+_32016256_320162560.652.4e-01Click!

Activity profile of mycb motif

Sorted Z-values of mycb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_6652396 0.88 ENSDART00000192813
ENSDART00000157678
nop53
NOP53 ribosome biogenesis factor
chr22_+_6293563 0.82 ENSDART00000063416
rnasel2
ribonuclease like 2
chr19_-_24555935 0.78 ENSDART00000132660
ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr2_+_50999675 0.77 ENSDART00000158064
ENSDART00000165746
ENSDART00000163917
ENSDART00000172038
ENSDART00000169048
ENSDART00000164775
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr19_-_24555623 0.68 ENSDART00000176022
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr8_-_46386024 0.64 ENSDART00000136602
ENSDART00000060919
ENSDART00000137472
qars
glutaminyl-tRNA synthetase
chr2_+_50999477 0.62 ENSDART00000190111
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr5_-_8765428 0.58 ENSDART00000167793
mybbp1a
MYB binding protein (P160) 1a
chr21_+_4509483 0.53 ENSDART00000025612
phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr10_+_29850330 0.52 ENSDART00000168898
hspa8
heat shock protein 8
chr10_+_29849977 0.51 ENSDART00000180242
hspa8
heat shock protein 8
chr2_-_42375275 0.50 ENSDART00000026339
gtpbp4
GTP binding protein 4
chr12_-_20350629 0.47 ENSDART00000066384
hbbe2
hemoglobin beta embryonic-2
chr22_+_835728 0.47 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr15_-_17099560 0.45 ENSDART00000101724
mos
v-mos Moloney murine sarcoma viral oncogene homolog
chr12_-_4301234 0.44 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr16_-_38629208 0.43 ENSDART00000126705
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr9_-_12888082 0.43 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr14_+_22076596 0.42 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr19_+_42983613 0.39 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr17_-_48705993 0.39 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr20_+_46660339 0.38 ENSDART00000016530
adcy3b
adenylate cyclase 3b
chr6_-_10752937 0.38 ENSDART00000135093
ola1
Obg-like ATPase 1
chr20_-_52882881 0.37 ENSDART00000111078
wu:fi04e12
wu:fi04e12
chr20_+_54079341 0.34 ENSDART00000060444
rps29
ribosomal protein S29
chr20_+_25445826 0.33 ENSDART00000012581
pfas
phosphoribosylformylglycinamidine synthase
chr1_-_19648227 0.33 ENSDART00000054574
polr1e
polymerase (RNA) I polypeptide E
chr9_+_907459 0.33 ENSDART00000034850
ENSDART00000144114
dbi
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr25_+_3328487 0.33 ENSDART00000181143
ldhbb
lactate dehydrogenase Bb
chr20_+_54666222 0.32 ENSDART00000166592
CABZ01087948.1

chr21_+_26071874 0.31 ENSDART00000003001
ENSDART00000146573
rpl23a
ribosomal protein L23a
chr24_+_33392698 0.31 ENSDART00000122579
si:ch73-173p19.1
si:ch73-173p19.1
chr23_+_38159715 0.31 ENSDART00000137969
zgc:112994
zgc:112994
chr13_-_35907768 0.31 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr3_+_28939759 0.30 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr4_-_2945306 0.30 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr5_-_60885935 0.30 ENSDART00000128350
rad51d
RAD51 paralog D
chr22_+_5118361 0.29 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr6_-_39080630 0.29 ENSDART00000021520
ENSDART00000128308
eif4bb
eukaryotic translation initiation factor 4Bb
chr5_-_54714789 0.28 ENSDART00000063357
ccnb1
cyclin B1
chr19_+_791538 0.28 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr5_+_3927989 0.28 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr14_-_12822 0.28 ENSDART00000180650
ENSDART00000188819
msx1a
muscle segment homeobox 1a
chr9_-_11587070 0.27 ENSDART00000030995
umps
uridine monophosphate synthetase
chr24_-_42090635 0.27 ENSDART00000166413
ssr1
signal sequence receptor, alpha
chr13_-_35892051 0.26 ENSDART00000145884
tacc3
transforming, acidic coiled-coil containing protein 3
chr6_-_13114406 0.26 ENSDART00000188015
zgc:194469
zgc:194469
chr8_+_26059677 0.26 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr15_-_44052927 0.26 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr10_+_29260096 0.26 ENSDART00000088973
sytl2a
synaptotagmin-like 2a
chr21_-_30408775 0.25 ENSDART00000101037
nhp2
NHP2 ribonucleoprotein homolog (yeast)
chr7_+_20344032 0.24 ENSDART00000144948
ENSDART00000138786
ponzr1
plac8 onzin related protein 1
chr5_-_54714525 0.24 ENSDART00000150138
ENSDART00000150070
ccnb1
cyclin B1
chr11_+_3959495 0.24 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr1_-_54972170 0.24 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr14_-_28568107 0.23 ENSDART00000042850
ENSDART00000145502
insb
preproinsulin b
chr22_-_607812 0.23 ENSDART00000145983
cdkn1a
cyclin-dependent kinase inhibitor 1A
chr4_-_14192254 0.23 ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr9_+_38158570 0.23 ENSDART00000059549
ENSDART00000133060
nifk
nucleolar protein interacting with the FHA domain of MKI67
chr1_-_26675969 0.23 ENSDART00000054184
trmo
tRNA methyltransferase O
chr13_+_13930263 0.22 ENSDART00000079154
rpia
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr9_+_12887491 0.22 ENSDART00000102386
si:ch211-167j6.4
si:ch211-167j6.4
chr11_-_30636163 0.22 ENSDART00000140516
zgc:153665
zgc:153665
chr25_+_29474982 0.22 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr13_+_15702142 0.21 ENSDART00000135960
trmt61a
tRNA methyltransferase 61A
chr5_+_72194444 0.21 ENSDART00000165436
ddx54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr25_+_37443194 0.21 ENSDART00000163178
ENSDART00000190262
slc10a3
solute carrier family 10, member 3
chr9_+_29985010 0.21 ENSDART00000020743
cmss1
cms1 ribosomal small subunit homolog (yeast)
chr11_-_21304452 0.21 ENSDART00000163008
RASSF5
si:dkey-85p17.3
chr3_-_40955780 0.21 ENSDART00000130130
cyp3c3
cytochrome P450, family 3, subfamily c, polypeptide 3
chr13_+_48359573 0.20 ENSDART00000161959
ENSDART00000165311
msh6
mutS homolog 6 (E. coli)
chr3_+_57997980 0.20 ENSDART00000168477
ENSDART00000193840
pycr1a
pyrroline-5-carboxylate reductase 1a
chr13_-_18345854 0.20 ENSDART00000080107
si:dkey-228d14.5
si:dkey-228d14.5
chr21_-_14832369 0.20 ENSDART00000144859
pus1
pseudouridylate synthase 1
chr8_-_52859301 0.20 ENSDART00000162004
nr5a1a
nuclear receptor subfamily 5, group A, member 1a
chr1_-_54971968 0.20 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr1_+_5485799 0.20 ENSDART00000022307
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr20_-_25645150 0.20 ENSDART00000063137
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr1_-_26676391 0.20 ENSDART00000152492
trmo
tRNA methyltransferase O
chr3_+_24595922 0.19 ENSDART00000169405
si:dkey-68o6.5
si:dkey-68o6.5
chr9_+_1339549 0.19 ENSDART00000082478
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr18_-_5850683 0.19 ENSDART00000082087
nip7
NIP7, nucleolar pre-rRNA processing protein
chr5_-_3927692 0.19 ENSDART00000146840
ENSDART00000058346
c1qbp
complement component 1, q subcomponent binding protein
chr9_+_1339194 0.18 ENSDART00000186976
ENSDART00000014766
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr5_-_16475374 0.18 ENSDART00000134274
ENSDART00000136004
piwil2
piwi-like RNA-mediated gene silencing 2
chr13_-_9061944 0.18 ENSDART00000164186
ENSDART00000102051
si:dkey-112g5.12
si:dkey-112g5.12
chr13_-_25199260 0.18 ENSDART00000057605
adka
adenosine kinase a
chr24_+_36317544 0.18 ENSDART00000048640
ENSDART00000156096
pus3
pseudouridylate synthase 3
chr7_+_1550966 0.18 ENSDART00000177863
ENSDART00000126840
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr12_+_33975065 0.17 ENSDART00000036649
sfxn2
sideroflexin 2
chr21_+_19517492 0.17 ENSDART00000123168
ENSDART00000187993
gzmk
granzyme K
chr23_-_38160024 0.17 ENSDART00000087112
pfdn4
prefoldin subunit 4
chr25_+_10909850 0.17 ENSDART00000186021
CR339041.3

chr25_+_19095231 0.17 ENSDART00000154066
isg20
interferon stimulated exonuclease gene
chr10_+_16036573 0.17 ENSDART00000188757
lmnb1
lamin B1
chr6_-_58975010 0.17 ENSDART00000144911
ENSDART00000144514
mars
methionyl-tRNA synthetase
chr2_-_20715094 0.16 ENSDART00000155439
dusp12
dual specificity phosphatase 12
chr24_-_16905018 0.16 ENSDART00000066759
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr15_+_17621375 0.16 ENSDART00000158352
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr11_-_12800945 0.15 ENSDART00000191178
txlng
taxilin gamma
chr5_-_61609448 0.15 ENSDART00000133426
si:dkey-261j4.5
si:dkey-261j4.5
chr3_+_23029934 0.15 ENSDART00000110343
nags
N-acetylglutamate synthase
chr9_+_27720428 0.14 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr15_-_43978141 0.14 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr11_-_12801157 0.14 ENSDART00000103449
txlng
taxilin gamma
chr2_+_39618951 0.14 ENSDART00000077108
zgc:136870
zgc:136870
chr22_+_28969071 0.14 ENSDART00000163427
pimr95
Pim proto-oncogene, serine/threonine kinase, related 95
chr7_+_41322407 0.14 ENSDART00000114076
ENSDART00000139093
dph2
DPH2 homolog (S. cerevisiae)
chr6_-_16456093 0.14 ENSDART00000083305
ENSDART00000181640
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr17_+_51627209 0.14 ENSDART00000056886
zgc:113142
zgc:113142
chr3_-_8765165 0.14 ENSDART00000191131
CABZ01058333.1

chr14_+_16287968 0.14 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr24_-_16904803 0.13 ENSDART00000165972
ENSDART00000149974
ENSDART00000149706
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr21_-_11199366 0.13 ENSDART00000167666
dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr13_+_25761279 0.13 ENSDART00000177818
ENSDART00000002863
neurog3
neurogenin 3
chr22_-_28777557 0.13 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr13_-_45022301 0.13 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr20_-_25631256 0.13 ENSDART00000048164
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr18_+_14277003 0.13 ENSDART00000006628
zgc:173742
zgc:173742
chr8_-_13471916 0.13 ENSDART00000146558
pimr105
Pim proto-oncogene, serine/threonine kinase, related 105
chr13_-_3516473 0.13 ENSDART00000146240
prkn
parkin RBR E3 ubiquitin protein ligase
chr21_-_45382112 0.13 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr1_-_29061285 0.13 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gemin8
gem (nuclear organelle) associated protein 8
chr8_-_13419049 0.13 ENSDART00000133656
pimr101
Pim proto-oncogene, serine/threonine kinase, related 101
chr7_+_33136545 0.12 ENSDART00000173485
itln2
intelectin 2
chr22_-_28777374 0.12 ENSDART00000188206
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr5_-_26950374 0.12 ENSDART00000050542
htra4
HtrA serine peptidase 4
chr1_-_14533611 0.12 ENSDART00000180678
CR847936.6

chr16_+_16968682 0.12 ENSDART00000111074
si:ch211-120k19.1
si:ch211-120k19.1
chr13_-_293250 0.12 ENSDART00000138581
chs1
chitin synthase 1
chr13_+_25199849 0.12 ENSDART00000139209
ENSDART00000130876
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr1_+_17376922 0.12 ENSDART00000145068
fat1a
FAT atypical cadherin 1a
chr24_+_16905188 0.11 ENSDART00000066760
cct5
chaperonin containing TCP1, subunit 5 (epsilon)
chr20_+_25625872 0.11 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr16_+_16969060 0.11 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr1_+_44390470 0.11 ENSDART00000100321
timm10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr9_-_11676491 0.11 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr22_+_17261801 0.11 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr17_+_51682429 0.11 ENSDART00000004379
nol10
nucleolar protein 10
chr19_-_791016 0.11 ENSDART00000037515
msto1
misato 1, mitochondrial distribution and morphology regulator
chr15_+_44053244 0.10 ENSDART00000059550
lrrc51
leucine rich repeat containing 51
chr21_+_19852532 0.10 ENSDART00000180572
fybb
FYN binding protein b
chr21_+_38638979 0.10 ENSDART00000143373
rbmx2
RNA binding motif protein, X-linked 2
chr9_+_41821613 0.10 ENSDART00000097295
col18a1a
collagen type XVIII alpha 1 chain a
chr24_+_32668675 0.09 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
si:ch211-282b22.1
chr13_+_39277178 0.09 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr17_-_42842129 0.09 ENSDART00000009528
mocs3
molybdenum cofactor synthesis 3
chr13_-_280652 0.09 ENSDART00000193627
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr13_-_4992395 0.09 ENSDART00000102651
nolc1
nucleolar and coiled-body phosphoprotein 1
chr4_+_36489448 0.09 ENSDART00000143181
znf1149
zinc finger protein 1149
chr11_+_2198831 0.09 ENSDART00000160515
hoxc6b
homeobox C6b
chr10_+_16036246 0.09 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr23_-_21535040 0.09 ENSDART00000010647
rcc2
regulator of chromosome condensation 2
chr9_-_27391908 0.09 ENSDART00000135221
nepro
nucleolus and neural progenitor protein
chr21_+_3941758 0.08 ENSDART00000181345
setx
senataxin
chr19_-_26964348 0.08 ENSDART00000103955
zbtb12.2
zinc finger and BTB domain containing 12, tandem duplicate 2
chr17_-_29771639 0.08 ENSDART00000086201
ush2a
Usher syndrome 2A (autosomal recessive, mild)
chr6_-_39653972 0.08 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr10_+_39283985 0.08 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr1_+_44800298 0.07 ENSDART00000073712
ENSDART00000187054
tmem187
transmembrane protein 187
chr15_+_42235449 0.07 ENSDART00000114801
ENSDART00000182053
SGPP2
sphingosine-1-phosphate phosphatase 2
chr22_-_20733822 0.07 ENSDART00000133780
si:dkey-3k20.1
si:dkey-3k20.1
chr7_-_39751540 0.07 ENSDART00000016803
grpel1
GrpE-like 1, mitochondrial
chr19_+_1005933 0.07 ENSDART00000191953
zdhhc3b
zinc finger, DHHC-type containing 3b
chr25_+_17405201 0.07 ENSDART00000164349
e2f4
E2F transcription factor 4
chr11_+_25296366 0.07 ENSDART00000065949
top1l
DNA topoisomerase I, like
chr9_-_56272465 0.06 ENSDART00000039235
lcp1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_-_21668082 0.06 ENSDART00000088513
gnl1
guanine nucleotide binding protein-like 1
chr23_-_21534455 0.06 ENSDART00000139092
rcc2
regulator of chromosome condensation 2
chr8_-_13678415 0.06 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
si:dkey-258f14.3
chr8_-_2246143 0.06 ENSDART00000135835
si:dkeyp-117b11.3
si:dkeyp-117b11.3
chr19_-_35229336 0.06 ENSDART00000054274
macf1a
microtubule-actin crosslinking factor 1a
chr11_+_25485774 0.06 ENSDART00000026249
gnl3l
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr25_+_17405458 0.06 ENSDART00000186711
e2f4
E2F transcription factor 4
chr10_-_39283883 0.06 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr1_+_31674297 0.06 ENSDART00000044214
wbp1lb
WW domain binding protein 1-like b
chr11_+_42478184 0.05 ENSDART00000089963
zgc:110286
zgc:110286
chr16_+_23960933 0.05 ENSDART00000146077
apoeb
apolipoprotein Eb
chr20_-_54259780 0.05 ENSDART00000172631
fkbp3
FK506 binding protein 3
chr3_-_47038481 0.05 ENSDART00000193260
CR392045.1

chr5_+_68807170 0.05 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr6_-_54078623 0.05 ENSDART00000154076
hyal1
hyaluronoglucosaminidase 1
chr2_+_9946121 0.05 ENSDART00000100696
tsen15
TSEN15 tRNA splicing endonuclease subunit
chr23_+_44644911 0.04 ENSDART00000140799
zgc:85858
zgc:85858
chr4_-_44611273 0.04 ENSDART00000156793
znf1115
zinc finger protein 1115
chr15_-_3940671 0.04 ENSDART00000189741
mindy4b
MINDY family member 4B
chr17_+_13099476 0.04 ENSDART00000012670
pnn
pinin, desmosome associated protein
chr15_-_2632891 0.04 ENSDART00000081840
cldnj
claudin j
chr11_+_30636351 0.04 ENSDART00000087909
tmem246
transmembrane protein 246
chr9_-_21460164 0.03 ENSDART00000133469
zmym2
zinc finger, MYM-type 2
chr13_+_30912117 0.03 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr20_+_35998073 0.03 ENSDART00000140457
opn5
opsin 5
chr25_+_30442389 0.03 ENSDART00000003346
pdcd2l
programmed cell death 2-like
chr2_+_19236969 0.03 ENSDART00000163875
ENSDART00000168644
cc2d1b
coiled-coil and C2 domain containing 1B
chr19_-_22346582 0.03 ENSDART00000045675
ENSDART00000169065
slc52a2
zgc:109744
solute carrier family 52 (riboflavin transporter), member 2
zgc:109744
chr9_-_27720612 0.03 ENSDART00000000566
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr14_+_20941038 0.03 ENSDART00000182539
zgc:66433
zgc:66433
chr12_-_34716037 0.03 ENSDART00000152876
bahcc1b
BAH domain and coiled-coil containing 1b
chr23_-_21534738 0.03 ENSDART00000134587
rcc2
regulator of chromosome condensation 2
chr2_-_10014821 0.03 ENSDART00000185525
CR956623.1

Network of associatons between targets according to the STRING database.

First level regulatory network of mycb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 0.4 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.3 GO:0042148 strand invasion(GO:0042148)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.3 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 1.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 1.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0044209 AMP salvage(GO:0044209)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.1 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.5 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0072078 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.0 1.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.1 GO:0045117 azole transport(GO:0045117)
0.0 0.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0001113 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.0 0.2 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.4 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0030428 cell septum(GO:0030428)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.9 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.3 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.2 GO:0032356 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.3 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.0 GO:0004540 ribonuclease activity(GO:0004540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC