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PRJNA207719: Tissue specific transcriptome profiling

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Results for mycn

Z-value: 2.13

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Transcription factors associated with mycn

Gene Symbol Gene ID Gene Info
mycn
ENSDARG00000006837 MYCN proto-oncogene, bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycndr11_v1_chr20_+_33294428_33294428-0.593.0e-01Click!

Activity profile of mycn motif

Sorted Z-values of mycn motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_2829049 1.84 ENSDART00000164913
PPP1R3G
si:ch211-152c8.5
chr11_-_37995501 1.59 ENSDART00000192096
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr16_-_21489514 1.29 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
mpp6a
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr15_-_21877726 1.18 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr19_-_24555935 1.15 ENSDART00000132660
ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr2_+_18988407 1.13 ENSDART00000170216
glula
glutamate-ammonia ligase (glutamine synthase) a
chr21_+_6780340 1.08 ENSDART00000139493
ENSDART00000140478
olfm1b
olfactomedin 1b
chr19_-_8940068 1.05 ENSDART00000043507
ciarta
circadian associated repressor of transcription a
chr19_-_24555623 0.91 ENSDART00000176022
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr13_-_12021566 0.89 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr17_+_19499157 0.84 ENSDART00000077804
slc22a15
solute carrier family 22, member 15
chr3_-_36764865 0.83 ENSDART00000173186
abcc6b.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr20_-_22798794 0.83 ENSDART00000148084
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr3_+_3810919 0.81 ENSDART00000056035
FQ311927.1

chr4_-_16824231 0.80 ENSDART00000014007
gys2
glycogen synthase 2
chr22_+_6293563 0.80 ENSDART00000063416
rnasel2
ribonuclease like 2
chr18_-_40684756 0.80 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
si:ch211-132b12.7
chr12_-_6159545 0.79 ENSDART00000152487
rltgr
RAMP-like triterpene glycoside receptor
chr6_-_59563597 0.78 ENSDART00000166311
INHBE
inhibin beta E subunit
chr24_-_38644937 0.77 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr22_-_20695237 0.75 ENSDART00000112722
org
oogenesis-related gene
chr7_+_6652967 0.74 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr4_-_16824556 0.71 ENSDART00000165289
ENSDART00000185839
gys2
glycogen synthase 2
chr9_+_56422517 0.70 ENSDART00000168620
gpr39
G protein-coupled receptor 39
chr4_-_2945306 0.68 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr9_+_56422311 0.66 ENSDART00000171958
gpr39
G protein-coupled receptor 39
chr5_-_8765428 0.65 ENSDART00000167793
mybbp1a
MYB binding protein (P160) 1a
chr6_-_8498908 0.65 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr20_-_38827623 0.65 ENSDART00000153310
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr12_-_22238004 0.64 ENSDART00000038310
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr24_+_33392698 0.64 ENSDART00000122579
si:ch73-173p19.1
si:ch73-173p19.1
chr7_+_20031202 0.62 ENSDART00000052904
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr10_-_26744131 0.62 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr14_-_30387894 0.62 ENSDART00000176136
slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr7_+_20030888 0.61 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr14_-_25452503 0.61 ENSDART00000148652
slc26a2
solute carrier family 26 (anion exchanger), member 2
chr13_-_4992395 0.60 ENSDART00000102651
nolc1
nucleolar and coiled-body phosphoprotein 1
chr3_+_23488652 0.60 ENSDART00000126282
nr1d1
nuclear receptor subfamily 1, group d, member 1
chr8_-_42238543 0.60 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr4_+_5180650 0.59 ENSDART00000067390
fgf6b
fibroblast growth factor 6b
chr1_+_29664336 0.59 ENSDART00000088290
raph1b
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b
chr2_+_49522178 0.57 ENSDART00000056254
stap2a
signal transducing adaptor family member 2a
chr7_-_60831082 0.57 ENSDART00000073654
ENSDART00000136999
pcxb
pyruvate carboxylase b
chr21_+_6114709 0.55 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr20_+_34915945 0.55 ENSDART00000153064
snap25a
synaptosomal-associated protein, 25a
chr20_+_46311707 0.54 ENSDART00000184743
flvcr2b
feline leukemia virus subgroup C cellular receptor family, member 2b
chr16_-_45327616 0.54 ENSDART00000158733
si:dkey-33i11.1
si:dkey-33i11.1
chr9_+_42066030 0.53 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr14_+_22447662 0.53 ENSDART00000161776
sowahab
sosondowah ankyrin repeat domain family member Ab
chr3_-_11972516 0.51 ENSDART00000140123
hmox2b
heme oxygenase 2b
chr16_+_40560622 0.51 ENSDART00000038294
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr24_+_2519761 0.51 ENSDART00000106619
nrn1a
neuritin 1a
chr5_-_43859148 0.51 ENSDART00000162746
ENSDART00000128763
si:ch211-204c21.1
si:ch211-204c21.1
chr12_-_9700605 0.51 ENSDART00000161063
heatr1
HEAT repeat containing 1
chr1_-_6494384 0.51 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr20_-_23439011 0.50 ENSDART00000022887
slc10a4
solute carrier family 10, member 4
chr21_-_4539899 0.49 ENSDART00000112460
dolk
dolichol kinase
chr6_+_29305190 0.49 ENSDART00000078647
si:ch211-201h21.5
si:ch211-201h21.5
chr5_-_20123002 0.49 ENSDART00000026516
pxmp2
peroxisomal membrane protein 2
chr24_+_34069675 0.48 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr16_+_23961276 0.48 ENSDART00000192754
apoeb
apolipoprotein Eb
chr6_-_29377092 0.47 ENSDART00000078665
tmem131
transmembrane protein 131
chr5_-_43959972 0.46 ENSDART00000180517
si:ch211-204c21.1
si:ch211-204c21.1
chr6_+_54239625 0.46 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr9_-_10003711 0.46 ENSDART00000124516
ENSDART00000102448
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr1_-_54706039 0.46 ENSDART00000083633
exosc1
exosome component 1
chr2_-_17393971 0.46 ENSDART00000100201
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr18_-_21218851 0.45 ENSDART00000060160
calb2a
calbindin 2a
chr10_-_7913591 0.45 ENSDART00000139661
slc35e4
solute carrier family 35, member E4
chr9_+_38158570 0.44 ENSDART00000059549
ENSDART00000133060
nifk
nucleolar protein interacting with the FHA domain of MKI67
chr5_-_54714789 0.44 ENSDART00000063357
ccnb1
cyclin B1
chr6_-_39653972 0.43 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr3_-_48612078 0.43 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr10_-_22831611 0.43 ENSDART00000160115
per1a
period circadian clock 1a
chr2_-_32512648 0.42 ENSDART00000170674
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr6_-_39167732 0.42 ENSDART00000153626
apof
apolipoprotein F
chr25_-_8138122 0.42 ENSDART00000104659
sergef
secretion regulating guanine nucleotide exchange factor
chr3_+_48561112 0.42 ENSDART00000159682
slc16a5b
solute carrier family 16 (monocarboxylate transporter), member 5b
chr21_-_22122312 0.42 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr9_-_18877597 0.41 ENSDART00000099446
kctd4
potassium channel tetramerization domain containing 4
chr4_-_18436899 0.41 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr16_+_13860299 0.41 ENSDART00000121998
grwd1
glutamate-rich WD repeat containing 1
chr16_+_23960744 0.41 ENSDART00000058965
apoeb
apolipoprotein Eb
chr1_-_45042210 0.40 ENSDART00000073694
smu1b
SMU1, DNA replication regulator and spliceosomal factor b
chr8_+_24854600 0.40 ENSDART00000156570
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr4_-_6809323 0.40 ENSDART00000099467
ifrd1
interferon-related developmental regulator 1
chr15_+_6652396 0.40 ENSDART00000192813
ENSDART00000157678
nop53
NOP53 ribosome biogenesis factor
chr5_-_54714525 0.40 ENSDART00000150138
ENSDART00000150070
ccnb1
cyclin B1
chr5_+_62356304 0.39 ENSDART00000148381
aspa
aspartoacylase
chr3_+_24595922 0.39 ENSDART00000169405
si:dkey-68o6.5
si:dkey-68o6.5
chr16_+_23960933 0.39 ENSDART00000146077
apoeb
apolipoprotein Eb
chr13_+_9678427 0.39 ENSDART00000153907
sema4ga
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ga
chr23_+_32101361 0.38 ENSDART00000138849
zgc:56699
zgc:56699
chr2_+_23613040 0.38 ENSDART00000026694
rpp40
ribonuclease P/MRP 40 subunit
chr7_+_7630409 0.38 ENSDART00000172934
clcn3
chloride channel 3
chr2_-_127945 0.37 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr1_-_8917902 0.37 ENSDART00000137900
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr9_-_12888082 0.37 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr7_-_55539738 0.37 ENSDART00000168721
ENSDART00000013796
ENSDART00000148514
aprt
adenine phosphoribosyltransferase
chr9_-_11587070 0.37 ENSDART00000030995
umps
uridine monophosphate synthetase
chr20_+_25626479 0.37 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr15_-_17099560 0.37 ENSDART00000101724
mos
v-mos Moloney murine sarcoma viral oncogene homolog
chr20_+_25445826 0.37 ENSDART00000012581
pfas
phosphoribosylformylglycinamidine synthase
chr23_-_43718067 0.36 ENSDART00000015777
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr25_-_35296165 0.36 ENSDART00000018107
fancf
Fanconi anemia, complementation group F
chr5_-_67993086 0.36 ENSDART00000049331
gtf3aa
general transcription factor IIIAa
chr9_-_31278048 0.36 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr14_+_14836468 0.35 ENSDART00000166728
si:dkey-102m7.3
si:dkey-102m7.3
chr8_+_40081403 0.35 ENSDART00000138036
lrrc75ba
leucine rich repeat containing 75Ba
chr5_+_57328535 0.35 ENSDART00000149646
slc31a1
solute carrier family 31 (copper transporter), member 1
chr13_-_330004 0.35 ENSDART00000093149
ddx21
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr17_+_24318753 0.35 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr13_-_35907768 0.35 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr21_+_6114305 0.35 ENSDART00000141607
fpgs
folylpolyglutamate synthase
chr12_+_34827808 0.35 ENSDART00000105533
tepsin
TEPSIN, adaptor related protein complex 4 accessory protein
chr3_+_33367954 0.35 ENSDART00000103161
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr20_-_45772306 0.34 ENSDART00000062092
trmt6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr2_+_205763 0.34 ENSDART00000160164
ENSDART00000101071
zgc:113293
zgc:113293
chr23_+_17522867 0.34 ENSDART00000002714
slc17a9b
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr1_+_54673846 0.34 ENSDART00000145018
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb
chr7_+_47243564 0.33 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr10_+_21434649 0.33 ENSDART00000193938
ENSDART00000064558
etf1b
eukaryotic translation termination factor 1b
chr13_+_15701849 0.32 ENSDART00000003517
trmt61a
tRNA methyltransferase 61A
chr17_+_22760126 0.32 ENSDART00000151999
ENSDART00000190442
ttc27
tetratricopeptide repeat domain 27
chr13_-_25199260 0.32 ENSDART00000057605
adka
adenosine kinase a
chr20_-_7000225 0.32 ENSDART00000100098
adcy1a
adenylate cyclase 1a
chr15_+_36156986 0.31 ENSDART00000059791
sst1.1
somatostatin 1, tandem duplicate 1
chr13_-_15142280 0.31 ENSDART00000163132
rab11fip5a
RAB11 family interacting protein 5a (class I)
chr18_+_17660402 0.31 ENSDART00000143475
cpne2
copine II
chr12_-_3453589 0.31 ENSDART00000175918
CABZ01063170.1

chr15_-_14552101 0.31 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr17_+_51682429 0.31 ENSDART00000004379
nol10
nucleolar protein 10
chr23_-_44677315 0.30 ENSDART00000143054
kif1c
kinesin family member 1C
chr19_+_10831362 0.30 ENSDART00000053325
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr14_+_16151636 0.30 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr5_+_43470544 0.30 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr19_+_20201254 0.30 ENSDART00000010140
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr4_-_16001118 0.30 ENSDART00000041070
ENSDART00000125389
mest
mesoderm specific transcript
chr15_+_22267847 0.29 ENSDART00000110665
spa17
sperm autoantigenic protein 17
chr7_+_41322407 0.29 ENSDART00000114076
ENSDART00000139093
dph2
DPH2 homolog (S. cerevisiae)
chr21_-_19919918 0.29 ENSDART00000137307
ENSDART00000142523
ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr5_-_55914268 0.29 ENSDART00000014049
wdr36
WD repeat domain 36
chr1_+_12195700 0.29 ENSDART00000040307
tdrd7a
tudor domain containing 7 a
chr5_-_13167097 0.29 ENSDART00000149700
ENSDART00000030213
mapk1
mitogen-activated protein kinase 1
chr15_-_3277635 0.29 ENSDART00000189094
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr16_-_42186093 0.29 ENSDART00000076030
fbl
fibrillarin
chr10_+_21559605 0.29 ENSDART00000123648
ENSDART00000108584
pcdh1a3
pcdh1a3
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr5_+_62723233 0.28 ENSDART00000183718
nanos2
nanos homolog 2
chr7_-_49801183 0.28 ENSDART00000052083
fjx1
four jointed box 1
chr11_-_12800945 0.28 ENSDART00000191178
txlng
taxilin gamma
chr11_-_12801157 0.28 ENSDART00000103449
txlng
taxilin gamma
chr10_-_33572441 0.28 ENSDART00000141231
si:dkey-18a10.3
si:dkey-18a10.3
chr16_+_46148990 0.28 ENSDART00000083919
sv2a
synaptic vesicle glycoprotein 2A
chr24_+_10302955 0.28 ENSDART00000112455
ENSDART00000066794
ENSDART00000149432
otulina
otulina
OTU deubiquitinase with linear linkage specificity a
OTU deubiquitinase with linear linkage specificity a
chr8_-_29851706 0.28 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr14_+_35748385 0.28 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr6_+_10450000 0.28 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr11_-_5865744 0.28 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr22_+_569565 0.27 ENSDART00000037069
usp49
ubiquitin specific peptidase 49
chr17_-_16069905 0.27 ENSDART00000110383
map7a
microtubule-associated protein 7a
chr13_+_13930263 0.27 ENSDART00000079154
rpia
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr14_+_16151368 0.27 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr8_-_19649617 0.27 ENSDART00000189033
fam78bb
family with sequence similarity 78, member B b
chr14_+_35748206 0.27 ENSDART00000177391
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr7_-_49800755 0.27 ENSDART00000180072
fjx1
four jointed box 1
chr2_+_29610114 0.27 ENSDART00000131271
dlgap1a
discs, large (Drosophila) homolog-associated protein 1a
chr14_+_37545639 0.27 ENSDART00000173192
pcdh1b
protocadherin 1b
chr13_-_3516473 0.27 ENSDART00000146240
prkn
parkin RBR E3 ubiquitin protein ligase
chr7_-_30779575 0.26 ENSDART00000004782
mphosph10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr18_-_5850683 0.26 ENSDART00000082087
nip7
NIP7, nucleolar pre-rRNA processing protein
chr9_+_49659114 0.26 ENSDART00000189643
CSRNP3
cysteine and serine rich nuclear protein 3
chr5_+_44228526 0.26 ENSDART00000143789
TMEM8B
si:dkey-84j12.1
chr25_-_8625601 0.25 ENSDART00000155280
GDPGP1
zgc:153343
chr10_+_5689510 0.25 ENSDART00000183217
ENSDART00000172632
pam
peptidylglycine alpha-amidating monooxygenase
chr17_+_17764979 0.25 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr25_+_37443194 0.25 ENSDART00000163178
ENSDART00000190262
slc10a3
solute carrier family 10, member 3
chr17_+_25955003 0.25 ENSDART00000156029
grid1a
glutamate receptor, ionotropic, delta 1a
chr1_+_56180416 0.25 ENSDART00000089358
crb3b
crumbs homolog 3b
chr22_+_17261801 0.25 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr7_-_12596727 0.25 ENSDART00000186413
adamtsl3
ADAMTS-like 3
chr6_+_3717613 0.25 ENSDART00000184330
ssb
Sjogren syndrome antigen B (autoantigen La)
chr19_-_30800004 0.25 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
trit1
tRNA isopentenyltransferase 1
chr19_+_20201593 0.25 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr12_+_3262564 0.25 ENSDART00000184264
tmem101
transmembrane protein 101
chr10_+_23022263 0.24 ENSDART00000138955
si:dkey-175g6.2
si:dkey-175g6.2
chr22_+_2793382 0.24 ENSDART00000144980
si:dkey-20i20.8
si:dkey-20i20.8
chr21_-_30408775 0.24 ENSDART00000101037
nhp2
NHP2 ribonucleoprotein homolog (yeast)
chr9_-_27391908 0.24 ENSDART00000135221
nepro
nucleolus and neural progenitor protein
chr1_+_37752171 0.24 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
GALNTL6
si:ch211-15e22.3
chr20_+_474288 0.24 ENSDART00000026794
nt5dc1
5'-nucleotidase domain containing 1
chr4_-_2727491 0.24 ENSDART00000141760
ENSDART00000039083
ENSDART00000134442
slco1c1
solute carrier organic anion transporter family, member 1C1
chr20_-_147574 0.24 ENSDART00000104762
ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr6_-_16456093 0.24 ENSDART00000083305
ENSDART00000181640
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr19_+_21820144 0.24 ENSDART00000181996
CU856623.1

chr3_-_31158382 0.24 ENSDART00000076764
ENSDART00000076796
smg1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr16_+_54674556 0.23 ENSDART00000167040
pop1
POP1 homolog, ribonuclease P/MRP subunit
chr12_+_24562667 0.23 ENSDART00000056256
nrxn1a
neurexin 1a
chr5_-_40190949 0.23 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr18_-_38244871 0.23 ENSDART00000076399
nat10
N-acetyltransferase 10
chr25_+_17689565 0.23 ENSDART00000171965
galnt18a
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a

Network of associatons between targets according to the STRING database.

First level regulatory network of mycn

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 1.2 GO:0034380 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
0.2 0.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.6 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.6 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.2 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.8 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.2 0.5 GO:0097037 heme export(GO:0097037)
0.2 1.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.6 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.4 GO:0015824 proline transport(GO:0015824)
0.1 0.4 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.4 GO:0044785 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.7 GO:0044209 AMP salvage(GO:0044209)
0.1 0.5 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.6 GO:1902765 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.3 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 0.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 1.4 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 1.6 GO:0009746 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.1 0.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.5 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.2 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.1 0.2 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.3 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.0 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 1.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 1.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 0.3 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.0 0.2 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.4 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 1.1 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.6 GO:0046686 response to cadmium ion(GO:0046686)
0.0 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.3 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0017145 stem cell division(GO:0017145)
0.0 0.2 GO:0045117 azole transport(GO:0045117)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.2 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.4 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.1 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.2 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 0.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.8 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.6 GO:0030681 ribonuclease MRP complex(GO:0000172) multimeric ribonuclease P complex(GO:0030681)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 4.1 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 1.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 1.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.6 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2 0.6 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.2 1.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.8 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.2 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway