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PRJNA207719: Tissue specific transcriptome profiling

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Results for neurod1

Z-value: 1.70

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Transcription factors associated with neurod1

Gene Symbol Gene ID Gene Info
neurod1
ENSDARG00000019566 neuronal differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
neurod1dr11_v1_chr9_-_44295071_442950710.903.8e-02Click!

Activity profile of neurod1 motif

Sorted Z-values of neurod1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_37130450 2.01 ENSDART00000183358
si:ch1073-174d20.1
si:ch1073-174d20.1
chr8_+_7359294 1.52 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr12_+_31744217 1.42 ENSDART00000190361
RNF157
si:dkey-49c17.3
chr20_+_405811 1.29 ENSDART00000149311
gpr63
G protein-coupled receptor 63
chr7_+_30823749 1.26 ENSDART00000085661
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr25_-_554142 1.23 ENSDART00000028997
myo9ab
myosin IXAb
chr23_+_20563779 1.23 ENSDART00000146008
camkvl
CaM kinase-like vesicle-associated, like
chr10_+_15777258 1.20 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr16_-_29334672 1.18 ENSDART00000162835
bcan
brevican
chr9_-_44295071 1.14 ENSDART00000011837
neurod1
neuronal differentiation 1
chr13_-_30027730 1.11 ENSDART00000044009
scdb
stearoyl-CoA desaturase b
chr19_-_32888758 1.09 ENSDART00000052080
laptm4b
lysosomal protein transmembrane 4 beta
chr10_+_15777064 1.09 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr11_-_28911172 1.00 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr21_-_43952958 1.00 ENSDART00000039571
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr20_-_39273987 0.98 ENSDART00000127173
clu
clusterin
chr11_+_35364445 0.98 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr12_-_16084835 0.97 ENSDART00000090881
kcnj19b
potassium voltage-gated channel, subfamily J, member 19b
chr6_-_43092175 0.97 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr2_+_50626476 0.96 ENSDART00000018150
neurod6b
neuronal differentiation 6b
chr1_-_38709551 0.95 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr6_-_11780070 0.94 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr5_-_23280098 0.94 ENSDART00000126540
ENSDART00000051533
plp1b
proteolipid protein 1b
chr7_+_32722227 0.92 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr16_-_8927425 0.90 ENSDART00000000382
triob
trio Rho guanine nucleotide exchange factor b
chr19_-_38830582 0.90 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr12_-_41619257 0.89 ENSDART00000162967
dpysl4
dihydropyrimidinase-like 4
chr5_-_40190949 0.89 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr7_-_58130703 0.89 ENSDART00000172082
ank2b
ankyrin 2b, neuronal
chr1_-_40227166 0.88 ENSDART00000146680
si:ch211-113e8.3
si:ch211-113e8.3
chr23_+_2778813 0.87 ENSDART00000142621
top1
DNA topoisomerase I
chr6_-_35487413 0.86 ENSDART00000102461
rgs8
regulator of G protein signaling 8
chr2_+_31475772 0.85 ENSDART00000130722
cacnb2b
calcium channel, voltage-dependent, beta 2b
chr1_-_29045426 0.85 ENSDART00000019770
gpm6ba
glycoprotein M6Ba
chr12_-_14922955 0.85 ENSDART00000002078
neurod2
neurogenic differentiation 2
chr7_+_29133321 0.84 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr4_-_1324141 0.83 ENSDART00000180720
ptn
pleiotrophin
chr10_-_17103651 0.80 ENSDART00000108959
RNF208
ring finger protein 208
chr24_-_17444067 0.79 ENSDART00000155843
cntnap2a
contactin associated protein like 2a
chr9_+_22634073 0.78 ENSDART00000181822
etv5a
ets variant 5a
chr3_-_46817838 0.78 ENSDART00000028610
elavl3
ELAV like neuron-specific RNA binding protein 3
chr5_-_51819027 0.78 ENSDART00000164267
homer1b
homer scaffolding protein 1b
chr10_-_24362775 0.77 ENSDART00000182104
pitpnab
phosphatidylinositol transfer protein, alpha b
chr12_+_21525496 0.77 ENSDART00000152974
ca10a
carbonic anhydrase Xa
chr3_-_60886984 0.77 ENSDART00000170974
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr25_+_7670683 0.77 ENSDART00000040275
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr3_-_46818001 0.75 ENSDART00000166505
elavl3
ELAV like neuron-specific RNA binding protein 3
chr5_-_46896541 0.74 ENSDART00000133240
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr21_-_16632808 0.74 ENSDART00000172645
unc5da
unc-5 netrin receptor Da
chr5_+_62611400 0.74 ENSDART00000132054
abr
active BCR-related
chr4_+_15968483 0.73 ENSDART00000101575
si:dkey-117n7.5
si:dkey-117n7.5
chr1_-_14233815 0.73 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr16_+_21738194 0.72 ENSDART00000163688
FP085428.1
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr21_+_13353263 0.71 ENSDART00000114677
si:ch73-62l21.1
si:ch73-62l21.1
chr22_-_33679277 0.71 ENSDART00000169948
FO904977.1

chr19_-_38872650 0.71 ENSDART00000146641
adgrb2
adhesion G protein-coupled receptor B2
chr18_-_39787040 0.71 ENSDART00000169916
dmxl2
Dmx-like 2
chr21_+_25181003 0.70 ENSDART00000169700
si:dkey-183i3.9
si:dkey-183i3.9
chr13_-_39830999 0.70 ENSDART00000115089
zgc:171482
zgc:171482
chr19_-_27261102 0.69 ENSDART00000143919
gabbr1b
gamma-aminobutyric acid (GABA) B receptor, 1b
chr23_+_35708730 0.68 ENSDART00000009277
tuba1a
tubulin, alpha 1a
chr19_-_9882821 0.68 ENSDART00000147128
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr5_-_10768258 0.68 ENSDART00000157043
rtn4r
reticulon 4 receptor
chr14_-_32258759 0.68 ENSDART00000052949
fgf13a
fibroblast growth factor 13a
chr21_-_12030654 0.67 ENSDART00000139145
tpgs2
tubulin polyglutamylase complex subunit 2
chr6_-_51101834 0.67 ENSDART00000092493
ptprt
protein tyrosine phosphatase, receptor type, t
chr17_-_20717845 0.67 ENSDART00000150037
ank3b
ankyrin 3b
chr25_+_14017609 0.66 ENSDART00000129105
ENSDART00000125733
chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr14_-_21219659 0.66 ENSDART00000089867
ppp2r2cb
protein phosphatase 2, regulatory subunit B, gamma b
chr5_-_40734045 0.66 ENSDART00000010896
isl1
ISL LIM homeobox 1
chr18_-_38087875 0.66 ENSDART00000111301
luzp2
leucine zipper protein 2
chr3_+_33340939 0.65 ENSDART00000128786
pyya
peptide YYa
chr12_-_3453589 0.65 ENSDART00000175918
CABZ01063170.1

chr11_+_24925434 0.65 ENSDART00000131431
sulf2a
sulfatase 2a
chr8_-_26609259 0.65 ENSDART00000027301
sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr20_-_39273505 0.65 ENSDART00000153114
clu
clusterin
chr21_+_25092300 0.65 ENSDART00000168505
dixdc1b
DIX domain containing 1b
chr18_-_42313798 0.65 ENSDART00000098639
cntn5
contactin 5
chr2_+_31476065 0.64 ENSDART00000049219
cacnb2b
calcium channel, voltage-dependent, beta 2b
chr8_-_17064243 0.63 ENSDART00000185313
rab3c
RAB3C, member RAS oncogene family
chr8_+_36500061 0.63 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr19_+_33553586 0.63 ENSDART00000183477
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_43226255 0.63 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr5_+_3501859 0.63 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr13_+_36633355 0.63 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr1_+_38775041 0.63 ENSDART00000110824
wdr17
WD repeat domain 17
chr7_+_10351038 0.63 ENSDART00000173256
si:cabz01029535.1
si:cabz01029535.1
chr7_+_26224211 0.63 ENSDART00000173999
vgf
VGF nerve growth factor inducible
chr5_-_18513950 0.62 ENSDART00000145878
si:dkey-215k6.1
si:dkey-215k6.1
chr10_+_29431529 0.62 ENSDART00000158154
dlg2
discs, large homolog 2 (Drosophila)
chr7_-_23996133 0.62 ENSDART00000173761
si:dkey-183c6.8
si:dkey-183c6.8
chr11_+_6159595 0.62 ENSDART00000178367
slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr5_+_36768674 0.62 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr25_-_20378721 0.62 ENSDART00000181707
kctd15a
potassium channel tetramerization domain containing 15a
chr13_+_28854438 0.62 ENSDART00000193407
ENSDART00000189554
CU639469.1

chr6_+_21095918 0.61 ENSDART00000167225
spega
SPEG complex locus a
chr12_-_41618844 0.61 ENSDART00000160054
dpysl4
dihydropyrimidinase-like 4
chr15_+_28955004 0.61 ENSDART00000029459
gipr
gastric inhibitory polypeptide receptor
chr6_+_22597362 0.61 ENSDART00000131242
cygb2
cytoglobin 2
chr5_+_20147830 0.60 ENSDART00000098727
svopa
SV2 related protein a
chr22_+_17205608 0.60 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr5_-_26493253 0.59 ENSDART00000088222
arvcfb
ARVCF, delta catenin family member b
chr10_+_17875891 0.59 ENSDART00000191744
phf24
PHD finger protein 24
chr3_-_21061931 0.59 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr10_-_24371312 0.59 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr24_+_24461341 0.58 ENSDART00000147658
bhlhe22
basic helix-loop-helix family, member e22
chr14_-_4556896 0.58 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr5_-_69923241 0.58 ENSDART00000187389
fktn
fukutin
chr13_+_3954540 0.58 ENSDART00000092646
lrrc73
leucine rich repeat containing 73
chr19_+_24882845 0.57 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr6_+_13787855 0.57 ENSDART00000182899
tmem198b
transmembrane protein 198b
chr17_-_36988455 0.57 ENSDART00000187180
ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr11_-_37359416 0.56 ENSDART00000159184
erc2
ELKS/RAB6-interacting/CAST family member 2
chr12_+_5190049 0.56 ENSDART00000126667
lgi1b
leucine-rich, glioma inactivated 1b
chr14_-_33083539 0.56 ENSDART00000160173
dlg3
discs, large homolog 3 (Drosophila)
chr5_+_24245682 0.56 ENSDART00000049003
atp6v1aa
ATPase H+ transporting V1 subunit Aa
chr13_-_44285793 0.55 ENSDART00000167383
CABZ01069436.1

chr20_-_18731268 0.55 ENSDART00000183893
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr24_-_34335265 0.55 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr2_+_30878864 0.55 ENSDART00000009326
oprk1
opioid receptor, kappa 1
chr10_-_31440500 0.55 ENSDART00000024778
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr16_-_29480335 0.55 ENSDART00000148930
lingo4b
leucine rich repeat and Ig domain containing 4b
chr12_+_5189776 0.54 ENSDART00000081298
lgi1b
leucine-rich, glioma inactivated 1b
chr8_-_6943155 0.54 ENSDART00000139545
ENSDART00000033294
wdr13
WD repeat domain 13
chr17_-_51829310 0.54 ENSDART00000154544
numb
numb homolog (Drosophila)
chr1_+_10683843 0.54 ENSDART00000054879
zgc:103678
zgc:103678
chr13_+_3954715 0.53 ENSDART00000182477
ENSDART00000192142
ENSDART00000190962
lrrc73
leucine rich repeat containing 73
chr6_+_39493864 0.53 ENSDART00000086263
mettl7a
methyltransferase like 7A
chr9_+_49712868 0.53 ENSDART00000192969
ENSDART00000183310
CSRNP3
cysteine and serine rich nuclear protein 3
chr3_+_38793499 0.53 ENSDART00000083394
kcnj19a
potassium voltage-gated channel subfamily J member 19a
chr17_-_44584811 0.53 ENSDART00000165059
ENSDART00000165252
slc35f4
solute carrier family 35, member F4
chr7_+_74134010 0.53 ENSDART00000164874
cldnd1a
claudin domain containing 1a
chr3_-_1204341 0.52 ENSDART00000089646
fam234b
family with sequence similarity 234, member B
chr12_+_46967789 0.52 ENSDART00000114866
oat
ornithine aminotransferase
chr18_-_38088099 0.52 ENSDART00000146120
luzp2
leucine zipper protein 2
chr11_-_32723851 0.52 ENSDART00000155592
pcdh17
protocadherin 17
chr7_-_50914526 0.52 ENSDART00000160398
ankrd46b
ankyrin repeat domain 46b
chr18_+_45550783 0.52 ENSDART00000138075
kifc3
kinesin family member C3
chr16_+_11151699 0.52 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr17_-_52579709 0.51 ENSDART00000156806
rps6kl1
ribosomal protein S6 kinase-like 1
chr7_+_69528850 0.51 ENSDART00000109507
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1
chr19_+_33732188 0.50 ENSDART00000151192
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr23_+_43954809 0.50 ENSDART00000164080
corin
corin, serine peptidase
chr21_+_44300689 0.49 ENSDART00000186298
ENSDART00000142810
gabra3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr15_+_32867420 0.49 ENSDART00000159442
dclk1b
doublecortin-like kinase 1b
chr2_-_21352101 0.49 ENSDART00000057021
hhatla
hedgehog acyltransferase like, a
chr13_-_39830816 0.49 ENSDART00000138981
zgc:171482
zgc:171482
chr20_-_44576949 0.49 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr2_-_22230326 0.49 ENSDART00000127810
fam110b
family with sequence similarity 110, member B
chr1_-_7893808 0.49 ENSDART00000110154
radil
Ras association and DIL domains
chr15_+_24691088 0.48 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr24_+_29449690 0.48 ENSDART00000105743
ENSDART00000193556
ENSDART00000145816
ntng1a
netrin g1a
chr5_-_48307804 0.48 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb
chr15_-_20954552 0.48 ENSDART00000006910
tbcela
tubulin folding cofactor E-like a
chr19_+_12801940 0.48 ENSDART00000040073
mc5ra
melanocortin 5a receptor
chr10_-_44508249 0.48 ENSDART00000160018
DUSP26
dual specificity phosphatase 26
chr25_-_35664817 0.47 ENSDART00000148718
lrrk2
leucine-rich repeat kinase 2
chr14_-_21218891 0.47 ENSDART00000158294
ppp2r2cb
protein phosphatase 2, regulatory subunit B, gamma b
chr5_-_38342992 0.47 ENSDART00000140337
mink1
misshapen-like kinase 1
chr12_+_26632448 0.47 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr2_+_7557912 0.47 ENSDART00000160053
ripk2
receptor-interacting serine-threonine kinase 2
chr5_+_42912966 0.46 ENSDART00000039973
rufy3
RUN and FYVE domain containing 3
chr18_+_9635178 0.46 ENSDART00000183486
pclob
piccolo presynaptic cytomatrix protein b
chr13_-_40499296 0.46 ENSDART00000158338
CNNM1
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr15_+_42933236 0.46 ENSDART00000167763
slc8a2b
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr24_+_24461558 0.46 ENSDART00000182424
bhlhe22
basic helix-loop-helix family, member e22
chr23_-_5032587 0.46 ENSDART00000163903
kcna2b
potassium voltage-gated channel, shaker-related subfamily, member 2b
chr18_+_27732285 0.45 ENSDART00000141835
tspan18b
tetraspanin 18b
chr12_+_32292564 0.45 ENSDART00000152945
ANKFN1
si:ch211-277e21.2
chr4_-_9667380 0.45 ENSDART00000189671
ENSDART00000133214
dmtf1
cyclin D binding myb-like transcription factor 1
chr21_+_7900107 0.45 ENSDART00000056560
ch25hl2
cholesterol 25-hydroxylase like 2
chr23_+_27912079 0.44 ENSDART00000171859
BX539336.1

chr20_+_48100261 0.44 ENSDART00000158604
xkr5a
XK related 5a
chr9_-_7673856 0.44 ENSDART00000102715
tuba8l3
tubulin, alpha 8 like 3
chr25_-_16818978 0.44 ENSDART00000104140
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr18_+_25003207 0.44 ENSDART00000099476
ENSDART00000132285
fam174b
family with sequence similarity 174, member B
chr1_+_21937201 0.44 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr21_+_40443118 0.44 ENSDART00000190675
ssh2b
slingshot protein phosphatase 2b
chr19_-_5812319 0.44 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr23_+_20705849 0.44 ENSDART00000079538
ccdc30
coiled-coil domain containing 30
chr16_-_35329803 0.44 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr1_+_32521469 0.43 ENSDART00000113818
ENSDART00000152580
nlgn4a
neuroligin 4a
chr10_-_5847904 0.43 ENSDART00000161096
ankrd55
ankyrin repeat domain 55
chr20_-_25669813 0.43 ENSDART00000153118
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr5_-_6433577 0.43 ENSDART00000160439
CABZ01037298.1

chr16_+_46000956 0.42 ENSDART00000101753
ENSDART00000162393
mtmr11
myotubularin related protein 11
chr10_-_43392267 0.41 ENSDART00000142872
edil3b
EGF-like repeats and discoidin I-like domains 3b
chr1_-_21297748 0.41 ENSDART00000142109
npy1r
neuropeptide Y receptor Y1
chr11_+_37049347 0.41 ENSDART00000109235
bicd2
bicaudal D homolog 2 (Drosophila)
chr18_+_10840071 0.41 ENSDART00000014496
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr17_+_26815021 0.41 ENSDART00000086885
asmt2
acetylserotonin O-methyltransferase 2
chr2_-_31800521 0.41 ENSDART00000112763
retreg1
reticulophagy regulator 1
chr16_-_34212912 0.41 ENSDART00000145017
phactr4b
phosphatase and actin regulator 4b
chr19_+_177455 0.41 ENSDART00000111580
tmem65
transmembrane protein 65
chr24_+_32472155 0.41 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr5_-_22019061 0.41 ENSDART00000113066
amer1
APC membrane recruitment protein 1
chr24_+_166892 0.40 ENSDART00000100417
lancl2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr13_+_25428677 0.40 ENSDART00000186284
si:dkey-51a16.9
si:dkey-51a16.9
chr17_-_2535682 0.40 ENSDART00000155227
ccdc9b
coiled-coil domain containing 9B
chr5_-_31904562 0.40 ENSDART00000140640
coro1cb
coronin, actin binding protein, 1Cb

Network of associatons between targets according to the STRING database.

First level regulatory network of neurod1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 1.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 0.9 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.3 1.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 1.2 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.2 0.7 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.2 0.8 GO:0060074 synapse maturation(GO:0060074)
0.2 1.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 0.5 GO:0060262 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.2 0.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.1 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.4 GO:0030186 melatonin metabolic process(GO:0030186)
0.1 0.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.7 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 0.4 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 1.0 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.4 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 0.6 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.4 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 1.5 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.6 GO:0021634 optic nerve formation(GO:0021634)
0.1 0.2 GO:0036076 ligamentous ossification(GO:0036076)
0.1 0.4 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.7 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 0.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 1.1 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.3 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.3 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.7 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.2 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.0 1.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.9 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.5 GO:1990709 presynaptic active zone assembly(GO:1904071) presynaptic active zone organization(GO:1990709)
0.0 0.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.4 GO:0061709 reticulophagy(GO:0061709)
0.0 0.1 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0044241 lipid digestion(GO:0044241)
0.0 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.7 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 1.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.7 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 2.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 1.3 GO:1901214 regulation of neuron death(GO:1901214)
0.0 0.1 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.3 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 1.0 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.5 GO:0098703 inorganic cation import into cell(GO:0098659) calcium ion import across plasma membrane(GO:0098703) inorganic ion import into cell(GO:0099587) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.5 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 1.0 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0021576 hindbrain formation(GO:0021576)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.1 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.0 1.0 GO:0003146 heart jogging(GO:0003146)
0.0 0.6 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.3 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.3 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0007631 feeding behavior(GO:0007631)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.1 GO:0001964 startle response(GO:0001964)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.2 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.0 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.0 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 2.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.5 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.0 GO:0021877 forebrain neuron fate commitment(GO:0021877)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043291 RAVE complex(GO:0043291)
0.2 1.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.7 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:0071439 clathrin complex(GO:0071439)
0.1 2.2 GO:0043204 perikaryon(GO:0043204)
0.1 0.9 GO:0043209 myelin sheath(GO:0043209)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 1.6 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.7 GO:0005771 multivesicular body(GO:0005771)
0.0 3.3 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0044304 main axon(GO:0044304)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 1.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.6 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.6 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 1.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.8 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 3.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.7 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.7 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 1.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.6 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.3 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.3 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 4.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.7 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.5 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.4 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.6 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.3 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0051020 GTPase binding(GO:0051020)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.7 GO:0016247 channel regulator activity(GO:0016247)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 4.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 ST ADRENERGIC Adrenergic Pathway
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)