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PRJNA207719: Tissue specific transcriptome profiling

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Results for nfia

Z-value: 2.87

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Transcription factors associated with nfia

Gene Symbol Gene ID Gene Info
nfia
ENSDARG00000062420 nuclear factor I/A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfiadr11_v1_chr22_-_16997246_169972460.246.9e-01Click!

Activity profile of nfia motif

Sorted Z-values of nfia motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_13256415 1.96 ENSDART00000144542
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr5_-_32292965 1.94 ENSDART00000183522
ENSDART00000131983
myhz1.2
myosin, heavy polypeptide 1.2, skeletal muscle
chr5_+_32228538 1.92 ENSDART00000077471
myhc4
myosin heavy chain 4
chr5_+_32222303 1.86 ENSDART00000051362
myhc4
myosin heavy chain 4
chr13_+_30804367 1.82 ENSDART00000053946
cxcl12a
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr5_+_32247310 1.74 ENSDART00000182649
myha
myosin, heavy chain a
chr13_+_50375800 1.43 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr22_-_26945493 1.37 ENSDART00000077411
cxcl12b
chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)
chr21_+_10866421 1.37 ENSDART00000137858
alpk2
alpha-kinase 2
chr9_-_6927587 1.35 ENSDART00000059092
tmem182a
transmembrane protein 182a
chr3_+_31039923 1.32 ENSDART00000147706
cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr14_-_7128980 1.32 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr5_-_32309129 1.32 ENSDART00000123003
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr12_-_17712393 1.31 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr16_-_13595027 1.22 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr21_-_11632403 1.21 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
cast
calpastatin
chr13_+_35689749 1.19 ENSDART00000158726
psme4a
proteasome activator subunit 4a
chr2_+_394166 1.17 ENSDART00000155733
mylk4a
myosin light chain kinase family, member 4a
chr25_+_20081553 1.16 ENSDART00000174684
tnni4b.1
troponin I4b, tandem duplicate 1
chr13_+_35690023 1.14 ENSDART00000128865
ENSDART00000130050
psme4a
proteasome activator subunit 4a
chr20_-_27311675 1.08 ENSDART00000026088
ENSDART00000148361
asb2a.1
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr15_-_23645810 1.07 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr17_-_6382392 1.06 ENSDART00000188051
ENSDART00000192560
ENSDART00000137389
ENSDART00000115389
txlnbb
taxilin beta b
chr7_+_29951997 1.06 ENSDART00000173453
tpma
alpha-tropomyosin
chr24_-_29822913 1.00 ENSDART00000160929
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr5_-_71705191 0.99 ENSDART00000187767
ak1
adenylate kinase 1
chr23_-_32162810 0.98 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr25_+_30298377 0.97 ENSDART00000153622
C11orf96
chromosome 11 open reading frame 96
chr23_-_21515182 0.94 ENSDART00000142000
rnf207b
ring finger protein 207b
chr21_-_13051613 0.93 ENSDART00000190777
myorg
myogenesis regulating glycosidase (putative)
chr16_+_29650698 0.92 ENSDART00000137153
tmod4
tropomodulin 4 (muscle)
chr10_+_15608326 0.91 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr23_+_31107685 0.90 ENSDART00000103448
tbx18
T-box 18
chr22_-_294700 0.89 ENSDART00000189179
CABZ01079179.1

chr8_+_46217861 0.88 ENSDART00000038790
angptl7
angiopoietin-like 7
chr23_+_36653376 0.88 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr22_+_28446365 0.86 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr13_+_24834199 0.85 ENSDART00000101274
zgc:153981
zgc:153981
chr25_-_10503043 0.85 ENSDART00000155404
cox8b
cytochrome c oxidase subunit 8b
chr21_-_22730832 0.84 ENSDART00000101797
fbxo40.1
F-box protein 40, tandem duplicate 1
chr21_+_21374277 0.84 ENSDART00000079431
rtn2b
reticulon 2b
chr17_+_10242166 0.83 ENSDART00000170420
clec14a
C-type lectin domain containing 14A
chr22_-_263117 0.83 ENSDART00000158134
zgc:66156
zgc:66156
chr12_+_6195191 0.76 ENSDART00000043236
ENSDART00000186420
prkg1b
protein kinase, cGMP-dependent, type Ib
chr19_-_9648542 0.74 ENSDART00000172628
clcn1a
chloride channel, voltage-sensitive 1a
chr16_+_12521872 0.74 ENSDART00000114411
rasip1
Ras interacting protein 1
chr23_+_20110086 0.74 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr4_+_26357221 0.73 ENSDART00000187684
ENSDART00000101545
ENSDART00000148296
ENSDART00000171433
tnni1d
troponin I, skeletal, slow d
chr5_+_37837245 0.73 ENSDART00000171617
epd
ependymin
chr4_-_77624155 0.72 ENSDART00000099761
si:ch211-250m6.7
si:ch211-250m6.7
chr19_-_37154436 0.71 ENSDART00000103155
cx39.4
connexin 39.4
chr1_-_41192059 0.71 ENSDART00000084665
ENSDART00000135369
dok7
docking protein 7
chr5_-_51830997 0.70 ENSDART00000163616
homer1b
homer scaffolding protein 1b
chr13_+_23162447 0.69 ENSDART00000180209
sorbs1
sorbin and SH3 domain containing 1
chr3_+_23221047 0.69 ENSDART00000009393
col1a1a
collagen, type I, alpha 1a
chr18_-_26101800 0.68 ENSDART00000004692
idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr4_-_17785120 0.68 ENSDART00000024775
mybpc1
myosin binding protein C, slow type
chr1_+_1689775 0.67 ENSDART00000048828
atp1a1a.4
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 4
chr7_-_41851605 0.67 ENSDART00000142981
mylk3
myosin light chain kinase 3
chr21_-_20932603 0.66 ENSDART00000138155
ENSDART00000079709
c6
complement component 6
chr9_-_33107237 0.65 ENSDART00000013918
casq2
calsequestrin 2
chr14_-_3268155 0.65 ENSDART00000177244
pdgfrb
platelet-derived growth factor receptor, beta polypeptide
chr24_+_9298198 0.63 ENSDART00000165780
otud1
OTU deubiquitinase 1
chr21_+_40484088 0.63 ENSDART00000161919
coro6
coronin 6
chr15_-_34567370 0.62 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr21_-_20840714 0.62 ENSDART00000144861
ENSDART00000139430
c6
complement component 6
chr5_+_24287927 0.61 ENSDART00000143563
zdhhc23a
zinc finger, DHHC-type containing 23a
chr22_+_16308450 0.61 ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr21_-_20832482 0.61 ENSDART00000191928
c6
complement component 6
chr14_-_6987649 0.60 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr20_+_25340814 0.60 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr6_+_13742899 0.60 ENSDART00000104722
cdk5r2a
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr2_-_38125657 0.60 ENSDART00000143433
cbln12
cerebellin 12
chr2_+_2470687 0.59 ENSDART00000184024
ENSDART00000061955
myl13
myosin, light chain 13
chr4_+_22480169 0.57 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr17_+_50701748 0.57 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr6_-_49078263 0.56 ENSDART00000032982
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr22_+_16308806 0.55 ENSDART00000162685
lrrc39
leucine rich repeat containing 39
chr14_-_29906209 0.54 ENSDART00000192952
sorbs2b
sorbin and SH3 domain containing 2b
chr21_+_11503212 0.53 ENSDART00000146701
si:dkey-184p9.7
si:dkey-184p9.7
chr24_-_5910811 0.53 ENSDART00000163012
pcolce2b
procollagen C-endopeptidase enhancer 2b
chr19_+_19412692 0.53 ENSDART00000113580
wu:fc38h03
wu:fc38h03
chr5_-_48268049 0.52 ENSDART00000187454
mef2cb
myocyte enhancer factor 2cb
chr10_-_17745345 0.52 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr12_-_26415499 0.52 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr15_+_43093044 0.50 ENSDART00000141125
kcne4
potassium voltage-gated channel, Isk-related family, member 4
chr20_+_19066858 0.49 ENSDART00000192086
sox7
SRY (sex determining region Y)-box 7
chr7_+_73308566 0.49 ENSDART00000187039
ENSDART00000174244
CABZ01081777.1

chr23_-_29667544 0.48 ENSDART00000059339
clstn1
calsyntenin 1
chr18_+_23218980 0.47 ENSDART00000185014
mef2aa
myocyte enhancer factor 2aa
chr12_+_46960579 0.46 ENSDART00000149032
oat
ornithine aminotransferase
chr2_+_45159855 0.46 ENSDART00000056333
CU929150.1

chr8_+_48613040 0.46 ENSDART00000121432
nppa
natriuretic peptide A
chr2_-_5404466 0.45 ENSDART00000152907
si:ch1073-184j22.2
si:ch1073-184j22.2
chr1_+_36651059 0.45 ENSDART00000187475
ednraa
endothelin receptor type Aa
chr24_-_24038800 0.45 ENSDART00000080549
lyz
lysozyme
chr22_-_36774219 0.45 ENSDART00000056151
ENSDART00000168711
acy1
aminoacylase 1
chr1_-_1627487 0.45 ENSDART00000166094
clic6
chloride intracellular channel 6
chr7_+_18364176 0.45 ENSDART00000171606
ENSDART00000186368
cd248a
CD248 molecule, endosialin a
chr23_+_5524247 0.45 ENSDART00000189679
ENSDART00000083622
tead3a
TEA domain family member 3 a
chr21_-_20939488 0.44 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr25_+_20089986 0.44 ENSDART00000143441
ENSDART00000184073
tnni4b.2
troponin I4b, tandem duplicate 2
chr1_+_53279861 0.44 ENSDART00000035713
rnf150a
ring finger protein 150a
chr10_+_26901222 0.44 ENSDART00000188766
ehbp1l1b
EH domain binding protein 1-like 1b
chr19_-_3381422 0.44 ENSDART00000105146
edn1
endothelin 1
chr4_-_12388535 0.44 ENSDART00000017180
rergla
RERG/RAS-like a
chr16_-_43356018 0.43 ENSDART00000181683
FO704821.1

chr11_-_24063196 0.43 ENSDART00000036513
trib3
tribbles pseudokinase 3
chr4_+_16725960 0.43 ENSDART00000034441
tcp11l2
t-complex 11, testis-specific-like 2
chr4_-_16412084 0.43 ENSDART00000188460
dcn
decorin
chr7_-_16558665 0.43 ENSDART00000169399
csrp3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr9_-_42696408 0.43 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr1_+_16463079 0.42 ENSDART00000078675
vps37a
vacuolar protein sorting 37A
chr8_-_17997845 0.41 ENSDART00000121660
acot11b
acyl-CoA thioesterase 11b
chr10_+_43189325 0.41 ENSDART00000185584
vcanb
versican b
chr5_-_57655092 0.41 ENSDART00000074290
mia
melanoma inhibitory activity
chr7_-_50517023 0.41 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr2_-_4787566 0.41 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr10_-_44008241 0.41 ENSDART00000137686
acads
acyl-CoA dehydrogenase short chain
chr19_-_25464291 0.40 ENSDART00000112915
umad1
UBAP1-MVB12-associated (UMA) domain containing 1
chr10_+_9195190 0.40 ENSDART00000136364
antxr2b
anthrax toxin receptor 2b
chr7_-_21905851 0.40 ENSDART00000111066
ENSDART00000020288
epoa
erythropoietin a
chr2_+_26237322 0.40 ENSDART00000030520
palm1b
paralemmin 1b
chr9_+_6587364 0.40 ENSDART00000122279
fhl2a
four and a half LIM domains 2a
chr12_+_26471712 0.40 ENSDART00000162115
ndel1a
nudE neurodevelopment protein 1-like 1a
chr17_+_20504196 0.40 ENSDART00000190539
neurl1ab
neuralized E3 ubiquitin protein ligase 1Ab
chr22_-_36774057 0.39 ENSDART00000125048
acy1
aminoacylase 1
chr6_-_10780698 0.39 ENSDART00000151714
gpr155b
G protein-coupled receptor 155b
chr16_-_17207754 0.39 ENSDART00000063804
wu:fj39g12
wu:fj39g12
chr21_-_20929575 0.39 ENSDART00000163889
c6
complement component 6
chr20_-_39273987 0.39 ENSDART00000127173
clu
clusterin
chr16_+_53387085 0.39 ENSDART00000154223
ENSDART00000101404
kif13a
kinesin family member 13A
chr5_-_30481263 0.39 ENSDART00000086734
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr2_-_6262441 0.39 ENSDART00000092190
arl14
ADP-ribosylation factor-like 14
chr6_-_6254432 0.38 ENSDART00000081952
rtn4a
reticulon 4a
chr14_-_30808174 0.38 ENSDART00000173262
prss23
protease, serine, 23
chr11_+_27364338 0.38 ENSDART00000186759
fbln2
fibulin 2
chr7_+_22688781 0.38 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr22_-_3595439 0.37 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr1_+_19933065 0.37 ENSDART00000161573
apbb2b
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr5_+_25680845 0.37 ENSDART00000139701
ENSDART00000009952
zfand5a
zinc finger, AN1-type domain 5a
chr6_+_26948093 0.37 ENSDART00000153595
farp2
FERM, RhoGEF and pleckstrin domain protein 2
chr4_+_14360372 0.37 ENSDART00000007103
nuak1a
NUAK family, SNF1-like kinase, 1a
chr14_+_30328567 0.36 ENSDART00000105889
mtus1a
microtubule associated tumor suppressor 1a
chr23_+_21663631 0.36 ENSDART00000066125
dhrs3a
dehydrogenase/reductase (SDR family) member 3a
chr7_+_22705656 0.36 ENSDART00000193008
si:dkey-165a24.9
si:dkey-165a24.9
chr24_+_15602 0.36 ENSDART00000161519
CABZ01109081.1

chr6_-_6248893 0.36 ENSDART00000124662
rtn4a
reticulon 4a
chr16_+_1254390 0.36 ENSDART00000092627
ADAMTSL4
ADAMTS like 4
chr8_+_24747865 0.36 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr21_-_20328375 0.35 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr24_+_21174523 0.34 ENSDART00000183849
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr9_+_6587056 0.34 ENSDART00000193421
fhl2a
four and a half LIM domains 2a
chr6_+_55277419 0.34 ENSDART00000083670
CABZ01041604.1

chr7_-_23745984 0.34 ENSDART00000048050
ITGB1BP2
zgc:92429
chr23_-_4855122 0.34 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr25_-_20523927 0.33 ENSDART00000114448
si:ch211-269c21.2
si:ch211-269c21.2
chr7_-_58776400 0.33 ENSDART00000167433
sox17
SRY (sex determining region Y)-box 17
chr19_-_46957968 0.33 ENSDART00000043713
angpt1
angiopoietin 1
chr15_-_28223757 0.33 ENSDART00000110969
ENSDART00000138401
scarf1
scavenger receptor class F, member 1
chr16_-_17525322 0.33 ENSDART00000189720
clcn1b
chloride channel, voltage-sensitive 1b
chr7_+_12835048 0.33 ENSDART00000016465
cx36.7
connexin 36.7
chr20_+_3934516 0.33 ENSDART00000165732
clec11a
C-type lectin domain containing 11A
chr18_+_23193820 0.33 ENSDART00000148106
mef2aa
myocyte enhancer factor 2aa
chr15_-_29387446 0.33 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr13_-_17723417 0.32 ENSDART00000183834
vdac2
voltage-dependent anion channel 2
chr2_-_16986894 0.31 ENSDART00000145720
clcn2a
chloride channel, voltage-sensitive 2a
chr13_+_35635672 0.31 ENSDART00000148481
thbs2a
thrombospondin 2a
chr14_+_18785727 0.31 ENSDART00000184452
si:ch211-111e20.1
si:ch211-111e20.1
chr24_+_9412450 0.31 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr13_+_36633355 0.31 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr24_+_2519761 0.31 ENSDART00000106619
nrn1a
neuritin 1a
chr22_-_3564563 0.30 ENSDART00000145114
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr21_+_25092300 0.30 ENSDART00000168505
dixdc1b
DIX domain containing 1b
chr12_+_30563550 0.30 ENSDART00000126064
si:ch211-28p3.4
si:ch211-28p3.4
chr24_+_34113424 0.30 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr6_-_41138854 0.30 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr15_+_21882419 0.30 ENSDART00000157216
si:dkey-103g5.4
si:dkey-103g5.4
chr3_-_50865079 0.30 ENSDART00000164295
pmp22a
peripheral myelin protein 22a
chr16_-_33806390 0.29 ENSDART00000160671
rspo1
R-spondin 1
chr1_+_2128970 0.29 ENSDART00000180074
ENSDART00000022019
ENSDART00000098059
mbnl2
muscleblind-like splicing regulator 2
chr5_+_28161079 0.29 ENSDART00000141109
tacr1a
tachykinin receptor 1a
chr16_-_5721386 0.29 ENSDART00000136655
ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr18_+_10820430 0.29 ENSDART00000161990
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr9_-_34871900 0.29 ENSDART00000026378
slc25a6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr18_+_38774584 0.28 ENSDART00000129750
fam214a
family with sequence similarity 214, member A
chr3_-_51912019 0.28 ENSDART00000149914
aatka
apoptosis-associated tyrosine kinase a
chr1_+_2129164 0.28 ENSDART00000074923
ENSDART00000124534
mbnl2
muscleblind-like splicing regulator 2
chr7_-_27037990 0.28 ENSDART00000173561
nucb2a
nucleobindin 2a
chr9_-_30160897 0.28 ENSDART00000143986
abi3bpa
ABI family, member 3 (NESH) binding protein a
chr7_-_34184282 0.28 ENSDART00000183284
smad6a
SMAD family member 6a
chr16_-_13613475 0.28 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr21_-_19314618 0.28 ENSDART00000188744
gpat3
glycerol-3-phosphate acyltransferase 3
chr17_+_27803608 0.28 ENSDART00000164943
qkia
QKI, KH domain containing, RNA binding a
chr4_-_72100774 0.28 ENSDART00000170099
slco1f1
solute carrier organic anion transporter family, member 1F1
chr1_-_45347393 0.28 ENSDART00000173024
si:ch211-243a20.4
si:ch211-243a20.4
chr4_+_74131530 0.28 ENSDART00000174125
CABZ01072523.1

chr14_-_32016615 0.27 ENSDART00000105761
zic3
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr5_+_53482597 0.27 ENSDART00000180333
BX323994.1

chr15_+_32297441 0.27 ENSDART00000153657
trim3a
tripartite motif containing 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of nfia

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.4 2.3 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 1.4 GO:0086005 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell action potential(GO:0086005) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 2.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.7 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 1.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 0.7 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.2 0.6 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 0.6 GO:0014909 smooth muscle cell migration(GO:0014909)
0.2 0.5 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.2 0.5 GO:1905072 cardiac jelly development(GO:1905072)
0.2 0.6 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.7 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 0.4 GO:0060585 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.5 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 1.0 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.4 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.7 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:0019532 oxalate transport(GO:0019532)
0.1 1.1 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 2.3 GO:0019835 cytolysis(GO:0019835)
0.1 0.2 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.5 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 1.8 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:1990544 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.0 GO:0000272 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.9 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 3.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.2 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.1 0.4 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 0.2 GO:0021985 neurohypophysis development(GO:0021985)
0.1 1.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 0.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.2 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.2 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.1 0.5 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.2 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.3 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.4 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:0061010 gall bladder development(GO:0061010)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0015874 norepinephrine transport(GO:0015874)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.7 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.3 GO:1901998 toxin transport(GO:1901998)
0.0 1.6 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.1 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.4 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0 0.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.8 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.1 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 1.6 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.6 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0002820 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0006182 cGMP biosynthetic process(GO:0006182) receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.4 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.9 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.0 0.8 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 2.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 1.8 GO:0001756 somitogenesis(GO:0001756)
0.0 0.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.6 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.3 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0006936 muscle contraction(GO:0006936)
0.0 0.6 GO:1901214 regulation of neuron death(GO:1901214)
0.0 0.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 2.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.3 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.0 GO:0018872 arsonoacetate metabolic process(GO:0018872)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 2.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 2.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 9.6 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 3.1 GO:0005861 troponin complex(GO:0005861)
0.1 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.2 GO:0043034 costamere(GO:0043034)
0.1 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.2 GO:0031430 M band(GO:0031430)
0.1 0.9 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 1.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.0 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 1.0 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.2 2.3 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 1.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 0.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.2 0.6 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.2 0.5 GO:0016496 substance P receptor activity(GO:0016496)
0.2 3.2 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 3.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0015288 voltage-gated anion channel activity(GO:0008308) porin activity(GO:0015288)
0.1 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.0 9.4 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.2 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.0 GO:0051020 GTPase binding(GO:0051020)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328) serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.0 0.5 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.0 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation