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PRJNA207719: Tissue specific transcriptome profiling

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Results for nfic

Z-value: 0.72

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Transcription factors associated with nfic

Gene Symbol Gene ID Gene Info
nfic
ENSDARG00000043210 nuclear factor I/C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nficdr11_v1_chr8_+_20624510_206245100.395.2e-01Click!

Activity profile of nfic motif

Sorted Z-values of nfic motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_55982940 0.80 ENSDART00000097753
ENSDART00000097751
nmrk2
nicotinamide riboside kinase 2
chr6_-_35401282 0.64 ENSDART00000127612
rgs5a
regulator of G protein signaling 5a
chr20_-_33976305 0.53 ENSDART00000111022
sele
selectin E
chr21_-_34658266 0.52 ENSDART00000023038
dacha
dachshund a
chr3_+_31039923 0.44 ENSDART00000147706
cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr12_+_30168342 0.41 ENSDART00000142756
ablim1b
actin binding LIM protein 1b
chr5_+_37517800 0.40 ENSDART00000048107
FP102018.1
Danio rerio latent transforming growth factor beta binding protein 3 (ltbp3), mRNA.
chr6_-_34006917 0.33 ENSDART00000190702
ENSDART00000184003
tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr1_-_7659870 0.32 ENSDART00000085203
efnb2b
ephrin-B2b
chr9_-_23884937 0.30 ENSDART00000141377
FAM124A
si:dkeyp-74a11.1
chr4_+_12292274 0.29 ENSDART00000061070
ENSDART00000150786
mkrn1
makorin, ring finger protein, 1
chr9_-_23885220 0.27 ENSDART00000112058
FAM124A
si:dkeyp-74a11.1
chr7_+_31051603 0.27 ENSDART00000108721
tjp1a
tight junction protein 1a
chr17_-_125091 0.26 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr8_-_14375890 0.25 ENSDART00000090306
xpr1a
xenotropic and polytropic retrovirus receptor 1a
chr20_+_51464670 0.24 ENSDART00000150110
thbd
thrombomodulin
chr11_+_13630107 0.24 ENSDART00000172220
si:ch211-1a19.3
si:ch211-1a19.3
chr21_+_10866421 0.22 ENSDART00000137858
alpk2
alpha-kinase 2
chr10_-_1718395 0.21 ENSDART00000137620
si:ch73-46j18.5
si:ch73-46j18.5
chr16_-_43041324 0.21 ENSDART00000155445
ENSDART00000156836
ENSDART00000154945
si:dkey-7j14.6
si:dkey-7j14.6
chr2_-_21167652 0.19 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr2_-_8017579 0.19 ENSDART00000040209
ephb3a
eph receptor B3a
chr11_-_17755444 0.19 ENSDART00000154627
eogt
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr3_-_37681824 0.18 ENSDART00000185858
gpatch8
G patch domain containing 8
chr7_-_55675617 0.18 ENSDART00000021009
ENSDART00000188631
cbfa2t3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr2_+_31665836 0.17 ENSDART00000135411
ENSDART00000143914
si:ch211-106h4.12
si:ch211-106h4.12
chr18_-_85294 0.17 ENSDART00000044387
gabpb1
GA binding protein transcription factor, beta subunit 1
chr12_+_30653047 0.15 ENSDART00000148562
thbs2b
thrombospondin 2b
chr14_+_15543331 0.15 ENSDART00000167025
si:dkey-203a12.7
si:dkey-203a12.7
chr1_+_35194454 0.15 ENSDART00000165389
sc:d189
sc:d189
chr15_+_31806303 0.15 ENSDART00000155902
frya
furry homolog a (Drosophila)
chr10_-_8358396 0.15 ENSDART00000059322
csgalnact1a
chondroitin sulfate N-acetylgalactosaminyltransferase 1a
chr16_+_23397785 0.15 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr4_-_17629444 0.14 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr11_-_24538852 0.14 ENSDART00000171004
ENSDART00000181039
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr19_+_30388186 0.14 ENSDART00000103474
tspan13b
tetraspanin 13b
chr1_+_7546259 0.13 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr6_-_6254432 0.12 ENSDART00000081952
rtn4a
reticulon 4a
chr12_-_35386910 0.12 ENSDART00000153453
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr7_+_36898850 0.12 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr13_-_22774491 0.12 ENSDART00000189320
si:ch211-150i13.1
si:ch211-150i13.1
chr5_-_46329880 0.12 ENSDART00000156577
si:ch211-130m23.5
si:ch211-130m23.5
chr7_+_37377335 0.11 ENSDART00000111842
sall1a
spalt-like transcription factor 1a
chr17_+_30546579 0.11 ENSDART00000154385
nhsl1a
NHS-like 1a
chr9_-_41323746 0.11 ENSDART00000140564
glsb
glutaminase b
chr24_-_22756508 0.11 ENSDART00000035409
ENSDART00000146247
zc2hc1a
zinc finger, C2HC-type containing 1A
chr2_-_30912922 0.11 ENSDART00000141669
myl12.2
myosin, light chain 12, genome duplicate 2
chr17_+_52822422 0.10 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr7_-_28647959 0.10 ENSDART00000150148
slc7a6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr6_-_35032792 0.10 ENSDART00000168256
ddr2a
discoidin domain receptor tyrosine kinase 2a
chr5_+_22791686 0.10 ENSDART00000014806
npas2
neuronal PAS domain protein 2
chr10_+_7636811 0.10 ENSDART00000160673
hint1
histidine triad nucleotide binding protein 1
chr16_+_21426524 0.10 ENSDART00000182869
gsdmeb
gasdermin Eb
chr16_+_50100420 0.10 ENSDART00000128167
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr11_-_270210 0.09 ENSDART00000005217
ENSDART00000172779
alas1
aminolevulinate, delta-, synthase 1
chr2_+_16460321 0.09 ENSDART00000145107
agfg1b
ArfGAP with FG repeats 1b
chr23_+_18944388 0.09 ENSDART00000104487
cox4i2
cytochrome c oxidase subunit IV isoform 2
chr4_+_74131530 0.09 ENSDART00000174125
CABZ01072523.1

chr15_+_24749985 0.09 ENSDART00000146107
ywhae1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
chr20_-_26588736 0.09 ENSDART00000134337
exoc2
exocyst complex component 2
chr17_-_30863252 0.08 ENSDART00000062811
yy1a
YY1 transcription factor a
chr11_-_43948885 0.08 ENSDART00000164522
CABZ01074203.1

chr1_+_28089703 0.08 ENSDART00000166989
psip1a
PC4 and SFRS1 interacting protein 1a
chr2_+_29257942 0.08 ENSDART00000184362
ENSDART00000025562
cdh18a
cadherin 18, type 2a
chr13_+_18371208 0.08 ENSDART00000138172
ccar1
cell division cycle and apoptosis regulator 1
chr12_+_35654749 0.07 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr4_+_22365061 0.07 ENSDART00000039277
lhfpl3
LHFPL tetraspan subfamily member 3
chr7_+_36898622 0.07 ENSDART00000190773
tox3
TOX high mobility group box family member 3
chr25_+_2993855 0.07 ENSDART00000163009
neo1b
neogenin 1b
chr6_-_8295657 0.07 ENSDART00000185135
slc44a2
solute carrier family 44 (choline transporter), member 2
chr25_+_4660639 0.07 ENSDART00000130299
deaf1
DEAF1 transcription factor
chr5_+_23211938 0.07 ENSDART00000090102
tpcn1
two pore segment channel 1
chr4_+_59589201 0.06 ENSDART00000150576
si:dkey-4e4.1
si:dkey-4e4.1
chr24_-_31942656 0.06 ENSDART00000180308
ENSDART00000016879
c1ql3a
complement component 1, q subcomponent-like 3a
chr20_-_3390406 0.06 ENSDART00000136987
rev3l
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_+_52049239 0.06 ENSDART00000036813
ccdc94
coiled-coil domain containing 94
chr12_+_22607761 0.06 ENSDART00000153112
si:dkey-219e21.2
si:dkey-219e21.2
chr7_+_30725473 0.06 ENSDART00000085716
mtmr10
myotubularin related protein 10
chr3_-_34279109 0.06 ENSDART00000183255
tnrc6c1
trinucleotide repeat containing 6C1
chr22_+_32120156 0.06 ENSDART00000149666
dock3
dedicator of cytokinesis 3
chr12_+_13405445 0.06 ENSDART00000089042
kcnh4b
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr22_+_39058269 0.05 ENSDART00000113362
ip6k1
inositol hexakisphosphate kinase 1
chr20_-_47188966 0.05 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr18_-_43880020 0.05 ENSDART00000185638
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr14_+_15484544 0.05 ENSDART00000188649
CR382326.1

chr19_+_9786722 0.05 ENSDART00000138310
cacng6a
calcium channel, voltage-dependent, gamma subunit 6a
chr7_-_29341233 0.05 ENSDART00000140938
ENSDART00000147251
trpm1a
transient receptor potential cation channel, subfamily M, member 1a
chr20_-_42100932 0.05 ENSDART00000191930
slc35f1
solute carrier family 35, member F1
chr12_+_4160804 0.05 ENSDART00000152515
itgam
integrin, alpha M (complement component 3 receptor 3 subunit)
chr25_-_36248053 0.05 ENSDART00000134928
nfatc3b
nuclear factor of activated T cells 3b
chr9_+_12934536 0.05 ENSDART00000134484
si:dkey-230p4.1
si:dkey-230p4.1
chr3_+_57038033 0.04 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr5_-_68826177 0.04 ENSDART00000136605
si:ch211-283h6.4
si:ch211-283h6.4
chr22_-_29083070 0.04 ENSDART00000104812
ENSDART00000172576
cbx6a
chromobox homolog 6a
chr14_+_21820034 0.04 ENSDART00000122739
ctbp1
C-terminal binding protein 1
chr16_-_12488365 0.04 ENSDART00000172750
slc2a3b
solute carrier family 2 (facilitated glucose transporter), member 3b
chr11_+_14284866 0.04 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr8_+_44722140 0.04 ENSDART00000163381
elmod3
ELMO/CED-12 domain containing 3
chr8_-_19467011 0.04 ENSDART00000162010
zgc:92140
zgc:92140
chr7_-_26306546 0.04 ENSDART00000140817
zgc:77439
zgc:77439
chr4_-_6416414 0.04 ENSDART00000191136
MDFIC
si:ch73-156e19.1
chr1_-_44434707 0.04 ENSDART00000110148
cryba1l2
crystallin, beta A1, like 2
chr13_+_22731356 0.03 ENSDART00000133064
nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr20_+_9474841 0.03 ENSDART00000053847
rad51b
RAD51 paralog B
chr4_+_30718997 0.03 ENSDART00000190901
CU207245.1

chr22_-_7129631 0.03 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr6_+_56076595 0.03 ENSDART00000169747
rtf2
replication termination factor 2 domain containing 1
chr8_-_6877390 0.03 ENSDART00000170883
ENSDART00000005321
neflb
neurofilament, light polypeptide b
chr17_-_43466317 0.03 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr1_-_28089557 0.03 ENSDART00000161024
ENSDART00000167875
snapc3
small nuclear RNA activating complex, polypeptide 3
chr20_+_25568694 0.03 ENSDART00000063107
ENSDART00000063128
cyp2p7
cytochrome P450, family 2, subfamily P, polypeptide 7
chr24_-_35707552 0.02 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr10_-_27566481 0.02 ENSDART00000078920
auts2a
autism susceptibility candidate 2a
chr16_-_43025885 0.02 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr10_-_16065185 0.02 ENSDART00000187266
si:dkey-184a18.5
si:dkey-184a18.5
chr18_+_19990412 0.02 ENSDART00000155054
ENSDART00000090310
pias1b
protein inhibitor of activated STAT, 1b
chr8_+_9699111 0.02 ENSDART00000111853
gripap1
GRIP1 associated protein 1
chr23_+_21278948 0.02 ENSDART00000156701
ENSDART00000033970
ubr4
ubiquitin protein ligase E3 component n-recognin 4
chr2_-_56649883 0.02 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr23_+_21978584 0.02 ENSDART00000145172
eif4g3b
eukaryotic translation initiation factor 4 gamma, 3b
chr4_-_6416155 0.02 ENSDART00000110535
MDFIC
si:ch73-156e19.1
chr17_-_35352690 0.02 ENSDART00000016053
rnf144aa
ring finger protein 144aa
chr17_+_5846202 0.02 ENSDART00000189713
fndc4b
fibronectin type III domain containing 4b
chr9_-_32142311 0.01 ENSDART00000142768
ankrd44
ankyrin repeat domain 44
chr18_+_9493720 0.01 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr19_+_40379771 0.01 ENSDART00000017917
ENSDART00000110699
vps50
vps50
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr5_-_32338866 0.01 ENSDART00000017956
ENSDART00000047670
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr16_+_30604387 0.01 ENSDART00000058785
fam210ab
family with sequence similarity 210, member Ab
chr7_+_27898091 0.01 ENSDART00000186451
ENSDART00000173510
tub
tubby bipartite transcription factor
chr3_-_33934788 0.01 ENSDART00000151411
gtf2f1
general transcription factor IIF, polypeptide 1
chr4_-_72179814 0.01 ENSDART00000172239
ENSDART00000189634
ENSDART00000186317
slco1f4
solute carrier organic anion transporter family, member 1F4
chr25_-_27564590 0.01 ENSDART00000073508
hyal4
hyaluronoglucosaminidase 4
chr12_+_19348538 0.01 ENSDART00000066388
tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr7_-_26306954 0.01 ENSDART00000057288
zgc:77439
zgc:77439
chr25_+_35058088 0.01 ENSDART00000156838
zgc:112234
zgc:112234
chr3_-_43646733 0.00 ENSDART00000180959
axin1
axin 1
chr25_-_17368231 0.00 ENSDART00000189291
cyp2x6
cytochrome P450, family 2, subfamily X, polypeptide 6
chr23_+_11669109 0.00 ENSDART00000091416
cntn3a.1
contactin 3a, tandem duplicate 1
chr2_+_47905735 0.00 ENSDART00000159701
ftr23
finTRIM family, member 23

Network of associatons between targets according to the STRING database.

First level regulatory network of nfic

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway