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PRJNA207719: Tissue specific transcriptome profiling

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Results for nkx1.2la

Z-value: 0.88

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Transcription factors associated with nkx1.2la

Gene Symbol Gene ID Gene Info
nkx1.2la
ENSDARG00000006350 NK1 transcription factor related 2-like,a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx1.2ladr11_v1_chr13_+_40770628_407706280.941.6e-02Click!

Activity profile of nkx1.2la motif

Sorted Z-values of nkx1.2la motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_21129752 1.46 ENSDART00000169764
syt1a
synaptotagmin Ia
chr6_+_57541776 1.17 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr20_-_29864390 1.15 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr8_+_16025554 1.13 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr2_+_50608099 1.06 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr15_-_33925851 0.97 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr2_-_38000276 0.93 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr23_-_15216654 0.91 ENSDART00000131649
sulf2b
sulfatase 2b
chr18_+_21408794 0.88 ENSDART00000140161
necab2
N-terminal EF-hand calcium binding protein 2
chr4_+_9669717 0.78 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr8_-_50888806 0.76 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr11_+_30057762 0.74 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr17_-_12385308 0.70 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr16_+_14033121 0.69 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1
chr22_-_20011476 0.69 ENSDART00000093312
ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr23_+_28582865 0.67 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr19_+_5480327 0.67 ENSDART00000148794
jupb
junction plakoglobin b
chr5_+_36611128 0.62 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr14_-_4556896 0.57 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr21_-_43015383 0.56 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr10_+_37137464 0.56 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr6_-_12275836 0.55 ENSDART00000189980
pkp4
plakophilin 4
chr4_+_9400012 0.53 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr20_-_42102416 0.52 ENSDART00000186378
ENSDART00000188253
ENSDART00000186458
slc35f1
solute carrier family 35, member F1
chr15_+_15856178 0.50 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr1_-_19215336 0.48 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr16_-_32837806 0.48 ENSDART00000003997
MCHR2
si:dkey-165n16.5
chr10_-_5581487 0.47 ENSDART00000141943
syk
spleen tyrosine kinase
chr5_+_37903790 0.42 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr7_+_34620418 0.42 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr2_+_53204750 0.41 ENSDART00000163644
zgc:165603
zgc:165603
chr1_-_50859053 0.41 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr18_+_24919614 0.41 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr12_+_47698356 0.39 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr15_-_14552101 0.37 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr12_-_41684729 0.36 ENSDART00000184461
jakmip3
Janus kinase and microtubule interacting protein 3
chr15_-_47115787 0.36 ENSDART00000192601
CABZ01079081.1

chr22_-_26865361 0.35 ENSDART00000182504
hmox2a
heme oxygenase 2a
chr21_+_13387965 0.35 ENSDART00000134347
zgc:113162
zgc:113162
chr5_+_1079423 0.35 ENSDART00000172231
si:zfos-128g4.2
si:zfos-128g4.2
chr6_+_7421898 0.34 ENSDART00000043946
ccdc65
coiled-coil domain containing 65
chr19_-_13286722 0.33 ENSDART00000168296
ENSDART00000158330
zfpm2b
zinc finger protein, FOG family member 2b
chr20_-_47188966 0.33 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr17_+_15983557 0.33 ENSDART00000190806
clmn
calmin
chr10_-_28118035 0.31 ENSDART00000190836
ENSDART00000088852
med13a
mediator complex subunit 13a
chr20_+_19512727 0.31 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr11_-_21528056 0.31 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr10_+_17235370 0.31 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr18_+_17827149 0.30 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr15_-_30505607 0.29 ENSDART00000155212
msi2b
musashi RNA-binding protein 2b
chr4_+_16885854 0.29 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr8_+_18011522 0.28 ENSDART00000136756
ssbp3b
single stranded DNA binding protein 3b
chr13_+_12761707 0.26 ENSDART00000015127
zgc:100846
zgc:100846
chr22_-_26865181 0.26 ENSDART00000138311
hmox2a
heme oxygenase 2a
chr8_-_13184989 0.26 ENSDART00000135738
zgc:194990
zgc:194990
chr21_+_21195487 0.25 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr17_+_24318753 0.25 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr5_+_36870737 0.25 ENSDART00000145182
slc8a2a
solute carrier family 8 (sodium/calcium exchanger), member 2a
chr4_-_2975461 0.24 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr6_+_37301341 0.24 ENSDART00000104180
zranb2
zinc finger, RAN-binding domain containing 2
chr1_-_19502322 0.24 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr21_+_11834880 0.24 ENSDART00000081661
nudt2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr16_-_30434279 0.23 ENSDART00000018504
zgc:77086
zgc:77086
chr13_-_39736938 0.22 ENSDART00000141645
zgc:171482
zgc:171482
chr4_+_11458078 0.22 ENSDART00000037600
ankrd16
ankyrin repeat domain 16
chr8_-_51930826 0.22 ENSDART00000109785
cabin1
calcineurin binding protein 1
chr11_+_16152316 0.21 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr4_+_25917915 0.20 ENSDART00000138603
vezt
vezatin, adherens junctions transmembrane protein
chr21_-_33995710 0.19 ENSDART00000100508
ENSDART00000179622
ebf1b
early B cell factor 1b
chr25_+_34938317 0.19 ENSDART00000042678
vps4a
vacuolar protein sorting 4a homolog A (S. cerevisiae)
chr10_-_5847655 0.19 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr23_-_20051369 0.19 ENSDART00000049836
bgnb
biglycan b
chr12_+_30706158 0.18 ENSDART00000133869
kcnk1a
potassium channel, subfamily K, member 1a
chr7_-_40630698 0.18 ENSDART00000134547
ube3c
ubiquitin protein ligase E3C
chr16_+_7985886 0.17 ENSDART00000126041
ano10a
anoctamin 10a
chr10_-_28117740 0.17 ENSDART00000134491
med13a
mediator complex subunit 13a
chr6_-_40922971 0.16 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr25_+_20715950 0.15 ENSDART00000180223
ergic2
ERGIC and golgi 2
chr8_+_52637507 0.15 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr7_-_58251527 0.14 ENSDART00000114008
ENSDART00000185189
unm_hu7910
un-named hu7910
chr7_-_31922432 0.14 ENSDART00000188398
lin7c
lin-7 homolog C (C. elegans)
chr16_-_27677930 0.14 ENSDART00000145991
tbrg4
transforming growth factor beta regulator 4
chr11_+_16153207 0.14 ENSDART00000192356
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr7_+_6941583 0.14 ENSDART00000160709
ENSDART00000157634
rbm14b
RNA binding motif protein 14b
chr21_-_15200556 0.14 ENSDART00000141809
sfswap
splicing factor SWAP
chr22_-_10055744 0.13 ENSDART00000143686
si:ch211-222k6.2
si:ch211-222k6.2
chr17_+_43032529 0.13 ENSDART00000055611
ENSDART00000154863
isca2
iron-sulfur cluster assembly 2
chr3_-_39180048 0.13 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr9_+_43799829 0.12 ENSDART00000186240
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr5_-_68074592 0.12 ENSDART00000165052
ENSDART00000018792
spag7
sperm associated antigen 7
chr1_-_28860732 0.12 ENSDART00000177588
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr15_+_9327252 0.11 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr11_-_29737088 0.11 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr3_-_12930217 0.11 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr22_+_9522971 0.11 ENSDART00000110048
strip1
striatin interacting protein 1
chr5_+_13394543 0.10 ENSDART00000051669
ENSDART00000135921
tctn2
tectonic family member 2
chr20_+_29209615 0.10 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr8_+_18588551 0.10 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr16_-_54971277 0.10 ENSDART00000113358
wdtc1
WD and tetratricopeptide repeats 1
chr11_+_2506516 0.10 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr14_+_30795559 0.09 ENSDART00000006132
cfl1
cofilin 1
chr1_+_33668236 0.09 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr10_-_2788668 0.09 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr22_-_8725768 0.09 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr15_+_23799461 0.09 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr5_-_51619742 0.08 ENSDART00000188537
otpb
orthopedia homeobox b
chr8_+_23521974 0.08 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr11_-_30158191 0.08 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr4_-_3353595 0.07 ENSDART00000009076
pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr14_+_36521005 0.06 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr13_-_10620652 0.06 ENSDART00000135000
ENSDART00000191587
si:ch73-54n14.2
camkmt
si:ch73-54n14.2
calmodulin-lysine N-methyltransferase
chr11_-_16152400 0.05 ENSDART00000123665
arpc4l
actin related protein 2/3 complex, subunit 4, like
chr1_-_7970653 0.04 ENSDART00000188909
si:dkey-79f11.7
si:dkey-79f11.7
chr21_+_6751405 0.04 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr15_+_34592215 0.04 ENSDART00000099776
tspan13a
tetraspanin 13a
chr11_-_2838699 0.04 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr2_+_8779164 0.04 ENSDART00000134308
zzz3
zinc finger, ZZ-type containing 3
chr24_-_29586082 0.04 ENSDART00000136763
vav3a
vav 3 guanine nucleotide exchange factor a
chr4_-_61691066 0.04 ENSDART00000159114
znf1129
zinc finger protein 1129
chr25_-_37248795 0.03 ENSDART00000087247
ENSDART00000154045
glg1a
golgi glycoprotein 1a
chr16_+_32051572 0.03 ENSDART00000039109
leng1
leukocyte receptor cluster (LRC) member 1
chr24_+_38301080 0.03 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr13_+_35339182 0.03 ENSDART00000019323
jag1b
jagged 1b
chr4_+_5255041 0.02 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr4_+_11723852 0.02 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr21_-_45363871 0.02 ENSDART00000075443
ENSDART00000182078
ENSDART00000151106
PPP2CA
zgc:56064
chr10_-_40968095 0.02 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr6_-_52566574 0.02 ENSDART00000098421
uqcc1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr18_+_49969568 0.02 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr24_-_31425799 0.01 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr8_+_11325310 0.01 ENSDART00000142577
fxn
frataxin
chr15_-_2596125 0.01 ENSDART00000114923
dnajc30b
DnaJ (Hsp40) homolog, subfamily C, member 30b
chr23_+_29885019 0.01 ENSDART00000167059
aurkaip1
aurora kinase A interacting protein 1
chr1_-_31171242 0.00 ENSDART00000190294
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx1.2la

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 0.5 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.6 GO:0006788 heme oxidation(GO:0006788)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 1.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.3 GO:0003352 regulation of cilium movement(GO:0003352)
0.0 0.3 GO:0036268 swimming(GO:0036268)
0.0 0.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.3 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0021767 mammillary body development(GO:0021767)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 1.8 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0045335 dendritic spine head(GO:0044327) phagocytic vesicle(GO:0045335)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0030882 lipid antigen binding(GO:0030882)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling