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PRJNA207719: Tissue specific transcriptome profiling

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Results for nkx2.2b

Z-value: 0.94

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Transcription factors associated with nkx2.2b

Gene Symbol Gene ID Gene Info
nkx2.2b
ENSDARG00000101549 NK2 homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2bdr11_v1_chr20_+_48782068_48782068-0.819.7e-02Click!

Activity profile of nkx2.2b motif

Sorted Z-values of nkx2.2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_33063083 0.98 ENSDART00000048550
si:ch211-125e6.5
si:ch211-125e6.5
chr2_-_24269911 0.78 ENSDART00000099532
myh7
myosin heavy chain 7
chr5_+_43782267 0.75 ENSDART00000130355
nos2a
nitric oxide synthase 2a, inducible
chr2_-_24270062 0.75 ENSDART00000192445
myh7
myosin heavy chain 7
chr22_+_11775269 0.67 ENSDART00000140272
krt96
keratin 96
chr8_+_25302172 0.65 ENSDART00000046182
ENSDART00000145316
gstm.3
glutathione S-transferase mu tandem duplicate 3
chr7_-_16562200 0.54 ENSDART00000169093
ENSDART00000173491
csrp3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr11_-_30636163 0.53 ENSDART00000140516
zgc:153665
zgc:153665
chr13_+_8840772 0.52 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr16_-_51288178 0.50 ENSDART00000079864
zgc:173729
zgc:173729
chr1_-_43905252 0.50 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
si:dkey-22i16.3
chr2_-_28396993 0.49 ENSDART00000188170
CABZ01056052.1

chr20_+_53577502 0.48 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr17_+_20616196 0.47 ENSDART00000153515
si:ch73-306e8.2
si:ch73-306e8.2
chr22_-_17631675 0.46 ENSDART00000132565
hmha1b
histocompatibility (minor) HA-1 b
chr3_-_33970190 0.45 ENSDART00000151238
ighj2-5
ighj2-5
chr14_+_17376940 0.45 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr11_-_25257595 0.43 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr17_+_20616576 0.42 ENSDART00000153561
si:ch73-306e8.2
si:ch73-306e8.2
chr24_+_38197852 0.41 ENSDART00000142949
igl3v4
immunoglobulin light 3 variable 4
chr17_+_6538733 0.41 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr2_-_10877228 0.40 ENSDART00000138718
ENSDART00000034246
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr22_+_835728 0.40 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr7_+_21275152 0.39 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr24_+_38205798 0.39 ENSDART00000141532
igl3v1
immunoglobulin light 3 variable 1
chr19_-_48330287 0.39 ENSDART00000162244
si:ch73-359m17.7
si:ch73-359m17.7
chr3_-_27647845 0.38 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr2_+_26498446 0.38 ENSDART00000078412
rps8a
ribosomal protein S8a
chr24_-_30263301 0.38 ENSDART00000162328
snx7
sorting nexin 7
chr6_+_13201358 0.37 ENSDART00000190290
CT009620.1

chr9_+_41156287 0.37 ENSDART00000189195
ENSDART00000186270
stat4
signal transducer and activator of transcription 4
chr23_-_39784368 0.36 ENSDART00000110282
si:ch211-286f9.2
si:ch211-286f9.2
chr22_+_19453822 0.35 ENSDART00000141371
si:dkey-78l4.6
si:dkey-78l4.6
chr7_+_50849142 0.35 ENSDART00000073806
pcolceb
procollagen C-endopeptidase enhancer b
chr12_+_6002715 0.35 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr5_+_1983495 0.35 ENSDART00000179860
CT573103.2

chr23_+_38245610 0.34 ENSDART00000191386
znf217
zinc finger protein 217
chr4_+_2230701 0.34 ENSDART00000080439
cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr11_+_14284866 0.33 ENSDART00000163729
si:ch211-262i1.3
si:ch211-262i1.3
chr25_+_10416583 0.33 ENSDART00000073907
ehf
ets homologous factor
chr24_-_36680261 0.32 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr4_-_22311610 0.32 ENSDART00000137814
hcls1
hematopoietic cell-specific Lyn substrate 1
chr8_+_1170015 0.32 ENSDART00000081457
ENSDART00000164116
ccl27a
chemokine (C-C motif) ligand 27a
chr7_-_8309505 0.32 ENSDART00000182530
f13a1b
coagulation factor XIII, A1 polypeptide b
chr21_+_19547806 0.32 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
rai14
retinoic acid induced 14
chr14_-_10617923 0.31 ENSDART00000133723
ENSDART00000131939
ENSDART00000136649
si:dkey-92i17.2
si:dkey-92i17.2
chr16_+_24842662 0.31 ENSDART00000157333
si:dkey-79d12.6
si:dkey-79d12.6
chr11_+_14286160 0.30 ENSDART00000166236
si:ch211-262i1.3
si:ch211-262i1.3
chr2_+_48282590 0.29 ENSDART00000035338
lpar5a
lysophosphatidic acid receptor 5a
chr6_+_49255706 0.29 ENSDART00000156866
si:dkey-183k8.2
si:dkey-183k8.2
chr8_+_52442622 0.29 ENSDART00000012758
zgc:77112
zgc:77112
chr8_-_45760087 0.29 ENSDART00000025620
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr2_-_58183499 0.28 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
si:ch1073-185p12.2
chr11_+_3308656 0.28 ENSDART00000082458
sarnp
SAP domain containing ribonucleoprotein
chr13_-_22699024 0.28 ENSDART00000016946
glud1a
glutamate dehydrogenase 1a
chr5_+_1877464 0.27 ENSDART00000050658
zgc:101699
zgc:101699
chr7_+_12950507 0.27 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr3_+_12829566 0.27 ENSDART00000157672
si:ch211-8c17.2
si:ch211-8c17.2
chr19_+_9344171 0.27 ENSDART00000133447
ENSDART00000104622
si:ch211-288g17.4
si:ch211-288g17.4
chr13_-_30996072 0.26 ENSDART00000181661
wdfy4
WDFY family member 4
chr2_+_36121373 0.26 ENSDART00000187002
CT867973.2

chr16_-_11798994 0.26 ENSDART00000135408
cnfn
cornifelin
chr1_-_49558223 0.26 ENSDART00000138510
si:ch211-281g13.4
si:ch211-281g13.4
chr8_-_38317914 0.25 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr4_-_9891874 0.25 ENSDART00000067193
adm2a
adrenomedullin 2a
chr11_-_7411436 0.25 ENSDART00000167312
adgrl4
adhesion G protein-coupled receptor L4
chr1_+_1915967 0.25 ENSDART00000131463
si:ch211-132g1.1
si:ch211-132g1.1
chr7_-_22790630 0.24 ENSDART00000173496
si:ch211-15b10.6
si:ch211-15b10.6
chr21_+_76739 0.24 ENSDART00000174654
ARSB
arylsulfatase B
chr3_+_19216567 0.24 ENSDART00000134433
il12rb2l
interleukin 12 receptor, beta 2a, like
chr5_-_37117778 0.24 ENSDART00000149138
il13ra2
interleukin 13 receptor, alpha 2
chr2_+_36114194 0.24 ENSDART00000113547
traj39
T-cell receptor alpha joining 39
chr3_-_11008532 0.24 ENSDART00000165086
CR382337.3

chr22_-_6941098 0.24 ENSDART00000105864
zgc:171500
zgc:171500
chr12_-_30558694 0.24 ENSDART00000153417
si:ch211-28p3.3
si:ch211-28p3.3
chr18_-_43866001 0.23 ENSDART00000150218
treh
trehalase (brush-border membrane glycoprotein)
chr19_+_40856807 0.23 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr21_-_36619599 0.23 ENSDART00000065208
nop16
NOP16 nucleolar protein homolog (yeast)
chr11_+_31285127 0.23 ENSDART00000160154
si:dkey-238i5.2
si:dkey-238i5.2
chr9_-_18911608 0.23 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr23_-_24394719 0.23 ENSDART00000044918
epha2b
eph receptor A2 b
chr21_+_33454147 0.22 ENSDART00000053208
rps14
ribosomal protein S14
chr5_-_38777852 0.22 ENSDART00000131603
si:dkey-58f10.4
si:dkey-58f10.4
chr16_+_35887868 0.22 ENSDART00000169677
ENSDART00000170772
thrap3a
thyroid hormone receptor associated protein 3a
chr4_+_6032640 0.21 ENSDART00000157487
tfec
transcription factor EC
chr1_+_55703120 0.21 ENSDART00000141089
adgre6
adhesion G protein-coupled receptor E6
chr9_+_18023288 0.21 ENSDART00000098355
tnfsf11
TNF superfamily member 11
chr5_+_3927989 0.21 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr5_-_30380593 0.21 ENSDART00000148039
snx19a
sorting nexin 19a
chr1_+_17900306 0.21 ENSDART00000089480
cyp4v8
cytochrome P450, family 4, subfamily V, polypeptide 8
chr15_+_37589698 0.21 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin37
lin-37 DREAM MuvB core complex component
chr24_-_26484298 0.21 ENSDART00000140647
eif5a
eukaryotic translation initiation factor 5A
chr2_+_1487118 0.21 ENSDART00000147283
c8a
complement component 8, alpha polypeptide
chr19_+_4066449 0.21 ENSDART00000162461
btr26
bloodthirsty-related gene family, member 26
chr13_-_40401870 0.21 ENSDART00000128951
nkx3.3
NK3 homeobox 3
chr2_-_51772438 0.21 ENSDART00000170241
BX908782.2
Danio rerio three-finger protein 5 (LOC100003647), mRNA.
chr22_+_883678 0.21 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr15_+_31526225 0.21 ENSDART00000154456
wdr95
WD40 repeat domain 95
chr1_+_55478653 0.21 ENSDART00000152441
adgre9
adhesion G protein-coupled receptor E9
chr8_-_38105053 0.21 ENSDART00000131546
adgra2
adhesion G protein-coupled receptor A2
chr20_-_39333657 0.20 ENSDART00000153720
ENSDART00000142164
ccl38.1
chemokine (C-C motif) ligand 38, duplicate 1
chr9_+_1313418 0.20 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr12_-_30548244 0.20 ENSDART00000193616
zgc:158404
zgc:158404
chr14_+_1170968 0.20 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr20_-_32045057 0.20 ENSDART00000152970
ENSDART00000034248
rab32a
RAB32a, member RAS oncogene family
chr4_-_25215968 0.20 ENSDART00000066932
ENSDART00000066933
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr23_+_19813677 0.20 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr7_-_17627320 0.19 ENSDART00000101701
nitr6a
novel immune-type receptor 6a
chr2_+_1486822 0.19 ENSDART00000132500
c8a
complement component 8, alpha polypeptide
chr20_+_492529 0.19 ENSDART00000141709
FO904980.1

chr13_+_18515126 0.19 ENSDART00000044697
tlr4ba
toll-like receptor 4b, duplicate a
chr15_-_1198886 0.19 ENSDART00000063285
lxn
latexin
chr9_-_9998087 0.19 ENSDART00000124423
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr8_-_49304602 0.19 ENSDART00000147020
prickle3
prickle homolog 3
chr3_-_34107685 0.19 ENSDART00000151130
ighv4-3
immunoglobulin heavy variable 4-3
chr22_-_4892937 0.19 ENSDART00000147002
si:ch73-256j6.4
si:ch73-256j6.4
chr15_-_20468302 0.19 ENSDART00000018514
dlc
deltaC
chr7_+_71586485 0.18 ENSDART00000165582
smchd1
structural maintenance of chromosomes flexible hinge domain containing 1
chr3_+_28581397 0.18 ENSDART00000150893
sept12
septin 12
chr23_+_35847538 0.18 ENSDART00000143935
rarga
retinoic acid receptor gamma a
chr9_+_33222911 0.18 ENSDART00000135387
si:ch211-125e6.14
si:ch211-125e6.14
chr4_-_12477224 0.18 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
arhgef39
Rho guanine nucleotide exchange factor (GEF) 39
chr5_+_28497956 0.18 ENSDART00000191935
nfr
notochord formation related
chr20_-_5267600 0.18 ENSDART00000099258
cyp46a1.4
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr1_+_55723870 0.18 ENSDART00000146614
adgre17
adhesion G protein-coupled receptor E17
chr1_-_55248496 0.18 ENSDART00000098615
nanos3
nanos homolog 3
chr9_+_40546677 0.18 ENSDART00000132911
vwc2l
von Willebrand factor C domain containing protein 2-like
chr5_+_42141917 0.18 ENSDART00000172201
ENSDART00000140743
trpv1
transient receptor potential cation channel, subfamily V, member 1
chr7_+_29992889 0.18 ENSDART00000055936
isl2b
ISL LIM homeobox 2b
chr13_-_865193 0.17 ENSDART00000187053
AL929536.7

chr8_-_43847138 0.17 ENSDART00000148358
adgrd1
adhesion G protein-coupled receptor D1
chr14_+_12169979 0.17 ENSDART00000129953
rhogd
ras homolog gene family, member Gd
chr12_+_23812530 0.17 ENSDART00000066331
svila
supervillin a
chr5_-_9073433 0.17 ENSDART00000099891
atp5meb
ATP synthase membrane subunit eb
chr7_+_65564163 0.17 ENSDART00000082679
mical2a
microtubule associated monooxygenase, calponin and LIM domain containing 2a
chr1_+_5485799 0.17 ENSDART00000022307
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr12_-_28794957 0.17 ENSDART00000020667
osbpl7
oxysterol binding protein-like 7
chr21_-_40835069 0.16 ENSDART00000004686
limk1b
LIM domain kinase 1b
chr4_-_16644708 0.16 ENSDART00000042307
sinhcaf
SIN3-HDAC complex associated factor
chr3_-_16110100 0.16 ENSDART00000051807
lasp1
LIM and SH3 protein 1
chr6_-_7439490 0.16 ENSDART00000188825
fkbp11
FK506 binding protein 11
chr8_-_50482781 0.16 ENSDART00000056361
ido1
indoleamine 2,3-dioxygenase 1
chr7_+_35268054 0.16 ENSDART00000113842
dpep2
dipeptidase 2
chr25_+_4635355 0.16 ENSDART00000021120
pgghg
protein-glucosylgalactosylhydroxylysine glucosidase
chr6_-_39024538 0.16 ENSDART00000165839
tns2b
tensin 2b
chr23_-_6765653 0.16 ENSDART00000192310
FP102169.1

chr14_-_733565 0.15 ENSDART00000158097
tlr1
toll-like receptor 1
chr4_+_69823638 0.15 ENSDART00000165786
znf1087
zinc finger protein 1087
chr17_+_19481049 0.15 ENSDART00000024194
kif11
kinesin family member 11
chr17_+_7513673 0.15 ENSDART00000156674
klhl10b.1
kelch-like family member 10b, tandem duplicate 1
chr3_+_4403980 0.15 ENSDART00000156881
CR774195.1

chr2_+_11028923 0.15 ENSDART00000076725
acot11a
acyl-CoA thioesterase 11a
chr6_-_26895314 0.15 ENSDART00000134259
hdlbpa
high density lipoprotein binding protein a
chr8_+_20624510 0.15 ENSDART00000138604
nfic
nuclear factor I/C
chr20_-_34090740 0.15 ENSDART00000062539
ENSDART00000008140
pdcb
phosducin b
chr12_+_36109507 0.15 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr11_+_37638873 0.15 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
sh2d5
SH2 domain containing 5
chr7_-_71585065 0.15 ENSDART00000128678
mettl4
methyltransferase like 4
chr14_-_9400552 0.14 ENSDART00000129485
ENSDART00000131341
tbx22
T-box 22
chr20_+_53368611 0.14 ENSDART00000060432
cdc40
cell division cycle 40 homolog (S. cerevisiae)
chr25_+_19008497 0.14 ENSDART00000104420
samm50
SAMM50 sorting and assembly machinery component
chr3_+_60761811 0.14 ENSDART00000053482
tsen54
TSEN54 tRNA splicing endonuclease subunit
chr12_-_3705862 0.14 ENSDART00000193864
ENSDART00000185857
CABZ01069040.1

chr16_+_5926520 0.14 ENSDART00000162229
ulk4
unc-51 like kinase 4
chr2_-_15324837 0.14 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr14_-_25956804 0.14 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr12_-_4301234 0.14 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr10_-_22117121 0.14 ENSDART00000149470
si:ch73-111e15.1
si:ch73-111e15.1
chr4_+_58576146 0.14 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr10_+_8481660 0.14 ENSDART00000109559
BX682234.1

chr6_-_1762191 0.14 ENSDART00000167928
orc4
origin recognition complex, subunit 4
chr18_-_6766354 0.14 ENSDART00000132611
adm2b
adrenomedullin 2b
chr13_-_25819825 0.14 ENSDART00000077612
rel
v-rel avian reticuloendotheliosis viral oncogene homolog
chr23_-_4409668 0.13 ENSDART00000081823
si:ch73-142c19.1
si:ch73-142c19.1
chr2_-_24402341 0.13 ENSDART00000155442
ENSDART00000088572
zgc:154006
zgc:154006
chr22_-_7700179 0.13 ENSDART00000145047
si:ch211-59h6.1
si:ch211-59h6.1
chr12_+_30726425 0.13 ENSDART00000153275
slc35f3a
solute carrier family 35, member F3a
chr21_+_5272059 0.13 ENSDART00000141981
loxhd1a
lipoxygenase homology domains 1a
chr4_+_31405646 0.13 ENSDART00000128732
si:rp71-5o12.3
si:rp71-5o12.3
chr14_+_34952883 0.13 ENSDART00000182812
il12ba
interleukin 12Ba
chr11_+_2398843 0.13 ENSDART00000126761
pip4k2cb
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b
chr14_-_46173265 0.13 ENSDART00000164321
zmp:0000000758
zmp:0000000758
chr15_-_37589600 0.13 ENSDART00000154641
proser3
proline and serine rich 3
chr15_+_37972671 0.13 ENSDART00000166764
si:dkey-238d18.9
si:dkey-238d18.9
chr16_+_20915319 0.13 ENSDART00000079383
hoxa9b
homeobox A9b
chr13_-_43238578 0.13 ENSDART00000161017
eif3s6ip
eukaryotic translation initiation factor 3, subunit 6 interacting protein
chr12_+_41348969 0.12 ENSDART00000171352
si:ch211-27e6.1
si:ch211-27e6.1
chr4_-_16876281 0.12 ENSDART00000016690
ENSDART00000044005
ENSDART00000042874
ENSDART00000125762
ENSDART00000185974
tmpoa
thymopoietin a
chr11_+_1565806 0.12 ENSDART00000137479
mybl2b
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr16_+_23913943 0.12 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr10_-_25343521 0.12 ENSDART00000166348
ENSDART00000009477
cct8
chaperonin containing TCP1, subunit 8 (theta)
chr1_-_354115 0.12 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr7_+_32901658 0.12 ENSDART00000115420
ano9b
anoctamin 9b
chr10_+_44373349 0.12 ENSDART00000172191
snrnp35
small nuclear ribonucleoprotein 35 (U11/U12)
chr1_+_23784905 0.12 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr20_+_25712276 0.12 ENSDART00000121585
ENSDART00000185772
cep135
centrosomal protein 135
chr13_+_44857087 0.12 ENSDART00000017770
zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr20_-_50049099 0.12 ENSDART00000123634
NDUFB1
NADH:ubiquinone oxidoreductase subunit B1
chr7_+_57108823 0.12 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr21_-_14310159 0.12 ENSDART00000155097
si:ch211-196i2.1
si:ch211-196i2.1

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.5 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.8 GO:0030826 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.4 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.5 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 0.2 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.2 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.2 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:0051818 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.0 0.4 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.2 GO:0006706 steroid catabolic process(GO:0006706) cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.2 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.5 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.1 GO:0009217 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.2 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.8 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.1 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade