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PRJNA207719: Tissue specific transcriptome profiling

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Results for nkx6.1

Z-value: 0.97

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Transcription factors associated with nkx6.1

Gene Symbol Gene ID Gene Info
nkx6.1
ENSDARG00000022569 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx6.1dr11_v1_chr21_+_19070921_190709210.984.5e-03Click!

Activity profile of nkx6.1 motif

Sorted Z-values of nkx6.1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_46111849 1.14 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr5_-_50781623 1.04 ENSDART00000114950
zgc:194908
zgc:194908
chr13_+_38430466 1.02 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr23_+_40460333 0.99 ENSDART00000184658
soga3b
SOGA family member 3b
chr9_-_32753535 0.97 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr17_-_16965809 0.91 ENSDART00000153697
nrxn3a
neurexin 3a
chr17_+_23298928 0.80 ENSDART00000153652
zgc:165461
zgc:165461
chr10_+_22381802 0.79 ENSDART00000112484
nlgn2b
neuroligin 2b
chr5_+_20147830 0.77 ENSDART00000098727
svopa
SV2 related protein a
chr12_+_24342303 0.76 ENSDART00000111239
nrxn1a
neurexin 1a
chr7_+_25059845 0.76 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr16_+_5774977 0.76 ENSDART00000134202
ccka
cholecystokinin a
chr5_-_23362602 0.76 ENSDART00000137120
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr14_+_50770537 0.75 ENSDART00000158723
sncb
synuclein, beta
chr17_+_15433518 0.74 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr9_+_31282161 0.74 ENSDART00000010774
zic2a
zic family member 2 (odd-paired homolog, Drosophila), a
chr17_-_29119362 0.74 ENSDART00000104204
foxg1a
forkhead box G1a
chr17_+_15433671 0.74 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr9_-_43538328 0.72 ENSDART00000140526
znf385b
zinc finger protein 385B
chr17_-_12389259 0.68 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr21_+_13366353 0.68 ENSDART00000151630
si:ch73-62l21.1
si:ch73-62l21.1
chr23_+_28731379 0.68 ENSDART00000047378
cort
cortistatin
chr23_+_20563779 0.64 ENSDART00000146008
camkvl
CaM kinase-like vesicle-associated, like
chr15_-_16098531 0.64 ENSDART00000080377
aldoca
aldolase C, fructose-bisphosphate, a
chr2_+_50608099 0.64 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr4_+_21129752 0.62 ENSDART00000169764
syt1a
synaptotagmin Ia
chr8_-_25120231 0.61 ENSDART00000147308
amigo1
adhesion molecule with Ig-like domain 1
chr1_+_34181581 0.60 ENSDART00000146042
epha6
eph receptor A6
chr22_-_13851297 0.60 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr8_+_24861264 0.60 ENSDART00000099607
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr13_+_38521152 0.59 ENSDART00000145292
adgrb3
adhesion G protein-coupled receptor B3
chr1_-_45042210 0.59 ENSDART00000073694
smu1b
SMU1, DNA replication regulator and spliceosomal factor b
chr10_-_24371312 0.59 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr7_-_28148310 0.59 ENSDART00000044208
lmo1
LIM domain only 1
chr1_+_12767318 0.59 ENSDART00000162652
pcdh10a
protocadherin 10a
chr14_-_4556896 0.58 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr1_+_12766351 0.58 ENSDART00000165785
pcdh10a
protocadherin 10a
chr8_+_7144066 0.58 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr2_+_20332044 0.57 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr19_-_31522625 0.57 ENSDART00000158438
ENSDART00000035049
necab1
N-terminal EF-hand calcium binding protein 1
chr16_+_34531486 0.57 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr18_+_9637744 0.57 ENSDART00000190171
pclob
piccolo presynaptic cytomatrix protein b
chr5_+_36611128 0.56 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr8_-_19051906 0.56 ENSDART00000089024
sema6bb
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr15_-_34213898 0.56 ENSDART00000191945
ENSDART00000186089
etv1
ets variant 1
chr5_+_63668735 0.56 ENSDART00000134261
ENSDART00000097330
dnm1b
dynamin 1b
chr9_-_20372977 0.56 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr1_+_8601935 0.55 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr12_+_5081759 0.54 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr20_+_18551657 0.53 ENSDART00000147001
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr24_+_2519761 0.53 ENSDART00000106619
nrn1a
neuritin 1a
chr9_-_31278048 0.52 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr15_+_22311803 0.52 ENSDART00000150182
hepacama
hepatic and glial cell adhesion molecule a
chr24_-_29963858 0.52 ENSDART00000183442
CR352310.1

chr1_+_33969015 0.52 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr25_-_20378721 0.51 ENSDART00000181707
kctd15a
potassium channel tetramerization domain containing 15a
chr11_-_37509001 0.51 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr4_+_12615836 0.51 ENSDART00000003583
lmo3
LIM domain only 3
chr14_+_14662116 0.51 ENSDART00000161693
cetn2
centrin, EF-hand protein, 2
chr20_+_41756996 0.51 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr18_-_1185772 0.51 ENSDART00000143245
nptnb
neuroplastin b
chr7_+_19552381 0.51 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr19_-_32641725 0.51 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr21_-_42100471 0.50 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr6_-_41229787 0.50 ENSDART00000065013
synpr
synaptoporin
chr20_+_31076488 0.50 ENSDART00000136255
ENSDART00000008840
otofa
otoferlin a
chr14_+_5936996 0.50 ENSDART00000097144
ENSDART00000126777
kctd8
potassium channel tetramerization domain containing 8
chr5_+_19314574 0.50 ENSDART00000133247
rusc2
RUN and SH3 domain containing 2
chr3_-_23406964 0.50 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr10_+_29698467 0.49 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr21_+_6780340 0.49 ENSDART00000139493
ENSDART00000140478
olfm1b
olfactomedin 1b
chr16_+_20161805 0.49 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr6_-_10320676 0.48 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr12_-_35787801 0.48 ENSDART00000171682
aatkb
apoptosis-associated tyrosine kinase b
chr20_-_27711970 0.48 ENSDART00000139637
zbtb25
zinc finger and BTB domain containing 25
chr7_-_28147838 0.48 ENSDART00000158921
lmo1
LIM domain only 1
chr3_-_40054615 0.48 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr3_-_18711288 0.47 ENSDART00000183885
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr19_+_6938289 0.46 ENSDART00000139122
ENSDART00000178832
flot1b
flotillin 1b
chr20_-_45060241 0.46 ENSDART00000185227
klhl29
kelch-like family member 29
chr1_-_44701313 0.46 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr23_-_26522760 0.46 ENSDART00000142417
ENSDART00000135606
ENSDART00000122668
si:dkey-205h13.1
si:dkey-205h13.1
chr20_+_40457599 0.46 ENSDART00000017553
serinc1
serine incorporator 1
chr18_+_34478959 0.45 ENSDART00000059394
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr21_+_28958471 0.45 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr20_-_28800999 0.45 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr2_-_40135942 0.45 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
epha4a
eph receptor A4a
chr6_-_38419318 0.45 ENSDART00000138026
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr8_-_34052019 0.45 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr22_-_11136625 0.45 ENSDART00000016873
ENSDART00000125561
atp6ap2
ATPase H+ transporting accessory protein 2
chr3_+_34919810 0.45 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr8_-_42238543 0.44 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr9_-_51436377 0.44 ENSDART00000006612
tbr1b
T-box, brain, 1b
chr12_+_35654749 0.43 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr3_+_29714775 0.43 ENSDART00000041388
cacng2a
calcium channel, voltage-dependent, gamma subunit 2a
chr22_-_7129631 0.42 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr12_-_26383242 0.42 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr11_+_36158134 0.42 ENSDART00000189827
ENSDART00000163330
grm2b
glutamate receptor, metabotropic 2b
chr14_+_49135264 0.42 ENSDART00000084119
si:ch1073-44g3.1
si:ch1073-44g3.1
chr4_-_8903240 0.41 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr12_-_33972798 0.41 ENSDART00000105545
arl3
ADP-ribosylation factor-like 3
chr9_-_3671911 0.41 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr19_-_31402429 0.41 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr5_-_31926906 0.41 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr1_-_22512063 0.40 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr2_+_38554260 0.40 ENSDART00000171527
cdh24b
cadherin 24, type 2b
chr6_+_39232245 0.40 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr10_+_37137464 0.40 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr19_-_5103313 0.40 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr25_+_15273370 0.40 ENSDART00000045659
tcp11l1
t-complex 11, testis-specific-like 1
chr18_+_24921587 0.40 ENSDART00000191345
rgma
repulsive guidance molecule family member a
chr15_-_6247775 0.39 ENSDART00000148350
dscamb
Down syndrome cell adhesion molecule b
chr8_-_39952727 0.39 ENSDART00000181310
cabp1a
calcium binding protein 1a
chr3_+_33341640 0.39 ENSDART00000186352
pyya
peptide YYa
chr6_-_35779348 0.38 ENSDART00000191159
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr3_-_28258462 0.38 ENSDART00000191573
rbfox1
RNA binding fox-1 homolog 1
chr24_+_5208171 0.38 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr3_-_35800221 0.38 ENSDART00000031390
caskin1
CASK interacting protein 1
chr10_-_34871737 0.38 ENSDART00000138755
dclk1a
doublecortin-like kinase 1a
chr8_-_50888806 0.38 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr1_+_25801648 0.37 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr14_+_45406299 0.37 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr11_-_8126223 0.37 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
ttll7
tubulin tyrosine ligase-like family, member 7
chr9_+_24159280 0.37 ENSDART00000184624
ENSDART00000178422
hecw2a
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr25_-_13842618 0.37 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr7_-_69521481 0.36 ENSDART00000148465
slc1a1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr9_+_34641237 0.36 ENSDART00000133996
shox
short stature homeobox
chr11_+_30057762 0.35 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr12_+_18681477 0.35 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr5_-_25174420 0.35 ENSDART00000141554
abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr11_+_36231248 0.35 ENSDART00000131104
GPR62 (1 of many)
si:ch211-213o11.11
chr17_-_19019635 0.35 ENSDART00000126666
flrt2
fibronectin leucine rich transmembrane protein 2
chr10_+_32683089 0.35 ENSDART00000063551
ppm1e
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr10_+_42423318 0.35 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr25_-_1720736 0.35 ENSDART00000097256
SLC6A13
solute carrier family 6 member 13
chr1_-_19215336 0.34 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr2_+_51183320 0.34 ENSDART00000167430
lrrc24
leucine rich repeat containing 24
chr18_-_42333428 0.34 ENSDART00000034225
cntn5
contactin 5
chr6_-_44044385 0.33 ENSDART00000075497
rybpb
RING1 and YY1 binding protein b
chr19_+_5480327 0.33 ENSDART00000148794
jupb
junction plakoglobin b
chr1_-_50859053 0.33 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr10_+_41765944 0.33 ENSDART00000171484
rnf34b
ring finger protein 34b
chr5_-_16996482 0.32 ENSDART00000144501
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr18_+_10884996 0.32 ENSDART00000147613
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr14_-_2933185 0.32 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr9_+_17983463 0.32 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr11_+_28476298 0.32 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr7_-_24699985 0.32 ENSDART00000052802
calb2b
calbindin 2b
chr3_-_20040636 0.32 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr1_-_36152131 0.32 ENSDART00000182113
ENSDART00000182904
znf827
zinc finger protein 827
chr10_-_34870667 0.32 ENSDART00000161272
dclk1a
doublecortin-like kinase 1a
chr20_-_29864390 0.32 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr2_-_30668580 0.32 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr1_+_11977426 0.32 ENSDART00000103399
tspan5b
tetraspanin 5b
chr6_-_12172424 0.32 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr23_+_28648864 0.32 ENSDART00000189096
l1cama
L1 cell adhesion molecule, paralog a
chr19_+_21362553 0.32 ENSDART00000122002
tshz1
teashirt zinc finger homeobox 1
chr13_-_30700460 0.31 ENSDART00000139073
rassf4
Ras association (RalGDS/AF-6) domain family member 4
chr7_+_31145386 0.31 ENSDART00000075407
ENSDART00000169462
fam189a1
family with sequence similarity 189, member A1
chr9_+_24159725 0.31 ENSDART00000137756
hecw2a
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr16_+_17389116 0.31 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr20_-_8304271 0.30 ENSDART00000179057
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr12_+_32073660 0.30 ENSDART00000153245
ENSDART00000153268
stxbp4
syntaxin binding protein 4
chr15_-_20024205 0.30 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr21_-_18648861 0.30 ENSDART00000112113
si:dkey-112m2.1
si:dkey-112m2.1
chr10_+_41765616 0.30 ENSDART00000170682
rnf34b
ring finger protein 34b
chr16_-_17162843 0.30 ENSDART00000089386
iffo1b
intermediate filament family orphan 1b
chr3_-_34337969 0.30 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr11_-_12998400 0.30 ENSDART00000018614
chrna4b
cholinergic receptor, nicotinic, alpha 4b
chr4_+_12612145 0.30 ENSDART00000181201
lmo3
LIM domain only 3
chr11_+_23760470 0.30 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
nfasca
neurofascin homolog (chicken) a
chr1_+_52929185 0.30 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr20_-_39271844 0.29 ENSDART00000192708
clu
clusterin
chr1_-_20271138 0.29 ENSDART00000185931
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr5_-_34185115 0.29 ENSDART00000192771
fibcd1
fibrinogen C domain containing 1
chr21_-_39177564 0.29 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr9_-_1702648 0.29 ENSDART00000102934
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr20_-_20930926 0.29 ENSDART00000123909
btbd6b
BTB (POZ) domain containing 6b
chr19_+_2279051 0.28 ENSDART00000182103
itgb8
integrin, beta 8
chr6_-_46162585 0.28 ENSDART00000017309
ca16b
carbonic anhydrase XVI b
chr18_-_2433011 0.28 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr16_+_2820340 0.28 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr11_+_24620742 0.28 ENSDART00000182471
ENSDART00000048365
syt6b
synaptotagmin VIb
chr12_-_28881638 0.28 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr15_-_22074315 0.28 ENSDART00000149830
drd2a
dopamine receptor D2a
chr6_+_21001264 0.27 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr11_+_30000814 0.27 ENSDART00000191011
ENSDART00000189770
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr14_-_4273396 0.27 ENSDART00000127318
frmpd1b
FERM and PDZ domain containing 1b
chr17_-_37052622 0.27 ENSDART00000186408
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr20_-_20931197 0.27 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr22_-_3564563 0.27 ENSDART00000145114
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr4_+_5798223 0.26 ENSDART00000059440
si:ch73-352p4.8
si:ch73-352p4.8
chr23_+_6795709 0.26 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr9_+_33009284 0.26 ENSDART00000036926
vangl1
VANGL planar cell polarity protein 1
chr7_-_54217547 0.26 ENSDART00000162777
ENSDART00000188268
ENSDART00000165875
csnk1g1
casein kinase 1, gamma 1
chr7_-_24994722 0.26 ENSDART00000131671
rcor2
REST corepressor 2
chr23_+_20705849 0.26 ENSDART00000079538
ccdc30
coiled-coil domain containing 30
chr19_-_7358184 0.26 ENSDART00000092379
oxr1b
oxidation resistance 1b
chr5_+_45976130 0.26 ENSDART00000175670
sv2c
synaptic vesicle glycoprotein 2C
chr13_+_36622100 0.26 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx6.1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0016322 neuron remodeling(GO:0016322)
0.2 1.0 GO:0021742 abducens nucleus development(GO:0021742)
0.2 0.6 GO:0015824 proline transport(GO:0015824)
0.2 1.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.6 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.5 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 1.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.5 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.8 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.4 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.6 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.7 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.6 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.2 GO:0036314 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.4 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.8 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.2 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 1.1 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.4 GO:0070206 protein trimerization(GO:0070206)
0.1 0.2 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.3 GO:0043584 nose development(GO:0043584)
0.1 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.2 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.1 0.3 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0 0.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.3 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 1.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.6 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 0.2 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0042311 vasodilation(GO:0042311)
0.0 0.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.5 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.6 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.6 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.4 GO:0032418 lysosome localization(GO:0032418)
0.0 0.6 GO:0007631 feeding behavior(GO:0007631)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.8 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988) synaptic membrane adhesion(GO:0099560)
0.0 0.1 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.0 GO:0097065 anterior head development(GO:0097065)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.2 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.0 0.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0007586 digestion(GO:0007586)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.1 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.0 GO:0051645 Golgi localization(GO:0051645)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.6 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0043083 synaptic cleft(GO:0043083)
0.3 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:0016600 flotillin complex(GO:0016600)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.2 GO:0097189 apoptotic body(GO:0097189)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.1 GO:0043679 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 2.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1903136 cuprous ion binding(GO:1903136)
0.2 0.6 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.2 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 0.6 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 1.0 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.3 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.2 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.5 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis