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PRJNA207719: Tissue specific transcriptome profiling

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Results for noto+vax1

Z-value: 0.37

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Transcription factors associated with noto+vax1

Gene Symbol Gene ID Gene Info
noto
ENSDARG00000021201 notochord homeobox
vax1
ENSDARG00000021916 ventral anterior homeobox 1
vax1
ENSDARG00000114230 ventral anterior homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
vax1dr11_v1_chr17_-_21441464_214414640.494.0e-01Click!
notodr11_v1_chr13_+_14976108_149761080.365.6e-01Click!

Activity profile of noto+vax1 motif

Sorted Z-values of noto+vax1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_31701716 0.18 ENSDART00000113370
b3glcta
beta 3-glucosyltransferase a
chr13_-_35808904 0.17 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr8_-_50888806 0.16 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr23_-_1348933 0.15 ENSDART00000168981
CABZ01078120.1

chr15_-_43284021 0.14 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr1_-_50859053 0.14 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr18_+_5137241 0.13 ENSDART00000159601
serpini1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr11_-_13107106 0.12 ENSDART00000184477
elovl1b
ELOVL fatty acid elongase 1b
chr6_+_32382743 0.12 ENSDART00000190009
dock7
dedicator of cytokinesis 7
chr25_+_28825657 0.12 ENSDART00000153625
nfybb
nuclear transcription factor Y, beta b
chr1_-_51719110 0.11 ENSDART00000190574
rnaseh2a
ribonuclease H2, subunit A
chr2_+_50608099 0.11 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr4_+_21129752 0.11 ENSDART00000169764
syt1a
synaptotagmin Ia
chr6_-_30954268 0.11 ENSDART00000154523
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr17_+_24722646 0.11 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr22_-_21897203 0.11 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr18_+_17827149 0.10 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr8_+_20140321 0.10 ENSDART00000012120
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr9_+_38372216 0.10 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr6_-_40581376 0.09 ENSDART00000185412
tspo
translocator protein
chr19_+_2631565 0.09 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr10_+_7593185 0.09 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
ppp2cb
protein phosphatase 2, catalytic subunit, beta isozyme
chr3_+_27798094 0.09 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr17_+_21902058 0.09 ENSDART00000142178
plekha1a
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr1_+_513986 0.09 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr20_-_37813863 0.09 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr18_-_2727764 0.09 ENSDART00000160841
ARHGEF17
si:ch211-248g20.5
chr20_+_11731039 0.09 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr6_+_40354424 0.08 ENSDART00000047416
slc4a8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr7_-_30174882 0.08 ENSDART00000110409
frmd5
FERM domain containing 5
chr21_-_42876565 0.08 ENSDART00000126480
zmp:0000001268
zmp:0000001268
chr2_+_56265791 0.07 ENSDART00000168335
homer3a
homer scaffolding protein 3a
chr13_+_35339182 0.07 ENSDART00000019323
jag1b
jagged 1b
chr3_-_32902138 0.07 ENSDART00000144026
ENSDART00000083874
ENSDART00000145443
ENSDART00000148239
ENSDART00000134917
kat7a
K(lysine) acetyltransferase 7a
chr9_+_30421489 0.06 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr10_-_33621739 0.06 ENSDART00000142655
ENSDART00000128049
hunk
hormonally up-regulated Neu-associated kinase
chr10_-_2524917 0.06 ENSDART00000188642
CU856539.1

chr20_+_29209615 0.06 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr20_-_46362606 0.06 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr11_+_43043171 0.06 ENSDART00000180344
CABZ01092982.1

chr18_-_2433011 0.06 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr4_-_73756673 0.06 ENSDART00000174274
ENSDART00000192913
ENSDART00000113546
BX855614.4
si:dkey-262g12.14
zgc:171551

si:dkey-262g12.14
zgc:171551
chr9_-_14683574 0.05 ENSDART00000144022
pard3bb
par-3 family cell polarity regulator beta b
chr5_+_41477954 0.05 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr5_-_66397688 0.05 ENSDART00000161483
hip1rb
huntingtin interacting protein 1 related b
chr11_-_42554290 0.05 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr16_+_43765993 0.05 ENSDART00000149154
si:dkey-122a22.2
si:dkey-122a22.2
chr18_+_3332999 0.05 ENSDART00000160857
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr9_-_5263947 0.05 ENSDART00000088342
cytip
cytohesin 1 interacting protein
chr5_+_30635309 0.05 ENSDART00000183769
abcg4a
ATP-binding cassette, sub-family G (WHITE), member 4a
chr10_+_16036246 0.05 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr3_-_15734530 0.05 ENSDART00000141142
mvp
major vault protein
chr21_-_26490186 0.05 ENSDART00000009889
zgc:110540
zgc:110540
chr19_-_20430892 0.05 ENSDART00000111409
tbc1d5
TBC1 domain family, member 5
chr16_-_7828838 0.04 ENSDART00000191434
ENSDART00000108653
tcaim
T cell activation inhibitor, mitochondrial
chr16_+_13818743 0.04 ENSDART00000090191
flcn
folliculin
chr15_+_44366556 0.04 ENSDART00000133449
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
chr4_+_9011448 0.04 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr15_+_1796313 0.04 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr3_-_15734358 0.04 ENSDART00000137325
mvp
major vault protein
chr12_+_30265802 0.04 ENSDART00000182412
afap1l2
actin filament associated protein 1-like 2
chr17_+_16046314 0.04 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr1_+_21731382 0.04 ENSDART00000054395
pax5
paired box 5
chr20_-_1635922 0.04 ENSDART00000181502
CR846082.1

chr2_-_26720854 0.04 ENSDART00000148110
si:dkey-181m9.8
si:dkey-181m9.8
chr5_+_41477526 0.04 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr10_+_43039947 0.03 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr20_+_29209767 0.03 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr10_+_29698467 0.03 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr10_+_28160265 0.03 ENSDART00000022484
rnft1
ring finger protein, transmembrane 1
chr5_-_15283509 0.03 ENSDART00000052712
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr19_-_2861444 0.03 ENSDART00000169053
clec3bb
C-type lectin domain family 3, member Bb
chr20_-_14924858 0.03 ENSDART00000047039
dnm3a
dynamin 3a
chr5_+_20257225 0.03 ENSDART00000127919
ssh1a
slingshot protein phosphatase 1a
chr12_+_22580579 0.03 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr20_-_14925281 0.03 ENSDART00000152641
dnm3a
dynamin 3a
chr22_+_19218733 0.03 ENSDART00000183212
ENSDART00000133595
si:dkey-21e2.7
si:dkey-21e2.7
chr12_+_47446158 0.02 ENSDART00000152857
fmn2b
formin 2b
chr18_-_46256560 0.02 ENSDART00000171375
si:dkey-244a7.1
si:dkey-244a7.1
chr19_+_32401278 0.02 ENSDART00000184353
atxn1a
ataxin 1a
chr7_-_12464412 0.02 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr16_+_14707960 0.02 ENSDART00000137912
col14a1a
collagen, type XIV, alpha 1a
chr20_-_18382708 0.02 ENSDART00000170864
ENSDART00000166762
ENSDART00000191333
vipas39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr8_-_52562672 0.02 ENSDART00000159333
ENSDART00000159974
si:ch73-199g24.2
si:ch73-199g24.2
chr3_-_61065055 0.02 ENSDART00000074199
cacng1b
calcium channel, voltage-dependent, gamma subunit 1b
chr13_+_15190677 0.02 ENSDART00000142240
ENSDART00000129045
mavs
mitochondrial antiviral signaling protein
chr7_-_46777876 0.02 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr8_-_25034411 0.02 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr20_+_29209926 0.01 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr14_-_14640401 0.01 ENSDART00000168027
ENSDART00000167521
znf185
zinc finger protein 185 with LIM domain
chr14_+_22591624 0.01 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr16_+_13818500 0.01 ENSDART00000135245
flcn
folliculin
chr6_-_40922971 0.01 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr15_-_22074315 0.01 ENSDART00000149830
drd2a
dopamine receptor D2a
chr12_+_34891529 0.01 ENSDART00000015643
tbcc
tubulin folding cofactor C
chr14_-_4145594 0.01 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr11_-_40728380 0.01 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr4_-_45100253 0.01 ENSDART00000163870
si:dkey-51d8.3
si:dkey-51d8.3
chr24_-_35282568 0.01 ENSDART00000167406
ENSDART00000088609
sntg1
syntrophin, gamma 1
chr3_-_34084387 0.00 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr21_-_37790727 0.00 ENSDART00000162907
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr12_+_20352400 0.00 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr18_+_9362455 0.00 ENSDART00000187025
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab

Network of associatons between targets according to the STRING database.

First level regulatory network of noto+vax1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.0 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.0 GO:0019777 Atg12 transferase activity(GO:0019777)