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PRJNA207719: Tissue specific transcriptome profiling

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Results for nr2c2

Z-value: 0.91

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Transcription factors associated with nr2c2

Gene Symbol Gene ID Gene Info
nr2c2
ENSDARG00000042477 nuclear receptor subfamily 2, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2c2dr11_v1_chr8_+_53120278_531202780.177.9e-01Click!

Activity profile of nr2c2 motif

Sorted Z-values of nr2c2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_60036767 1.25 ENSDART00000155009
tgm8
transglutaminase 8
chr23_-_45705525 1.19 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr22_-_15587360 1.02 ENSDART00000142717
ENSDART00000138978
tpm4a
tropomyosin 4a
chr3_+_39566999 0.94 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr7_+_31871830 0.92 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr7_+_31838320 0.91 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr17_+_53424415 0.82 ENSDART00000157022
slc9a1b
solute carrier family 9 member A1b
chr21_-_19006631 0.77 ENSDART00000080269
ENSDART00000191682
pgam2
phosphoglycerate mutase 2 (muscle)
chr11_+_11201096 0.71 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr10_+_35417099 0.66 ENSDART00000063398
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr5_-_36837846 0.61 ENSDART00000032481
ckma
creatine kinase, muscle a
chr15_-_29598679 0.57 ENSDART00000155153
si:ch211-207n23.2
si:ch211-207n23.2
chr9_-_43082945 0.56 ENSDART00000142257
ccdc141
coiled-coil domain containing 141
chr16_-_22713152 0.56 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
si:ch211-105c13.3
chr23_+_42810055 0.54 ENSDART00000186647
myl9a
myosin, light chain 9a, regulatory
chr10_-_22797959 0.51 ENSDART00000183269
pcolcea
procollagen C-endopeptidase enhancer a
chr3_-_12187245 0.47 ENSDART00000189553
ENSDART00000165131
srl
sarcalumenin
chr6_-_40722200 0.46 ENSDART00000035101
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr18_+_1615 0.44 ENSDART00000082450
homer2
homer scaffolding protein 2
chr11_+_77526 0.43 ENSDART00000193521
CABZ01072242.1

chr17_+_53425037 0.43 ENSDART00000154983
fabp10b
fatty acid binding protein 10b, liver basic
chr1_-_59240975 0.42 ENSDART00000166170
mvb12a
multivesicular body subunit 12A
chr6_-_40722480 0.41 ENSDART00000188187
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr3_-_34561624 0.38 ENSDART00000129313
sept9a
septin 9a
chr14_+_989733 0.38 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr6_-_14004772 0.37 ENSDART00000185629
zgc:92027
zgc:92027
chr6_+_1787160 0.37 ENSDART00000113505
myl9b
myosin, light chain 9b, regulatory
chr1_+_58353661 0.37 ENSDART00000140074
si:dkey-222h21.2
si:dkey-222h21.2
chr3_+_27770110 0.37 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr17_+_15788100 0.36 ENSDART00000027667
rragd
ras-related GTP binding D
chr17_+_33418475 0.35 ENSDART00000169145
snap23.1
synaptosomal-associated protein 23.1
chr9_+_35077546 0.35 ENSDART00000142688
si:dkey-192g7.3
si:dkey-192g7.3
chr8_+_15251448 0.35 ENSDART00000063717
zgc:171480
zgc:171480
chr16_-_24612871 0.35 ENSDART00000155614
ENSDART00000154787
ENSDART00000155983
ENSDART00000156519
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr6_+_27339962 0.35 ENSDART00000193726
klhl30
kelch-like family member 30
chr23_+_19790962 0.34 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr3_-_18410968 0.34 ENSDART00000041842
ndufb10
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr7_+_24114694 0.34 ENSDART00000127177
mrpl52
mitochondrial ribosomal protein L52
chr25_+_15647993 0.33 ENSDART00000186578
ENSDART00000031828
spon1b
spondin 1b
chr6_-_49873020 0.32 ENSDART00000148511
gnas
GNAS complex locus
chr7_+_24115082 0.32 ENSDART00000182718
mrpl52
mitochondrial ribosomal protein L52
chr11_-_6974022 0.31 ENSDART00000172851
COMP
si:ch211-43f4.1
chr3_+_301479 0.30 ENSDART00000165169
CABZ01075611.1

chr23_-_44903048 0.30 ENSDART00000149103
fhdc5
FH2 domain containing 5
chr8_+_31872992 0.30 ENSDART00000146933
c7a
complement component 7a
chr22_-_31020690 0.30 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr3_-_32590164 0.30 ENSDART00000151151
tspan4b
tetraspanin 4b
chr5_+_22579975 0.30 ENSDART00000080877
tnfsf10l4
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr19_+_2631565 0.29 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr21_-_308852 0.29 ENSDART00000151613
lhfpl2a
LHFPL tetraspan subfamily member 2a
chr13_-_37127970 0.29 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr5_+_24282570 0.29 ENSDART00000041905
zdhhc23a
zinc finger, DHHC-type containing 23a
chr22_+_29994093 0.28 ENSDART00000104778
si:dkey-286j15.3
si:dkey-286j15.3
chr18_+_8917766 0.28 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr20_-_49117438 0.27 ENSDART00000057700
naa20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr16_-_25233515 0.27 ENSDART00000058943
zgc:110182
zgc:110182
chr20_+_15015557 0.27 ENSDART00000039345
myoc
myocilin
chr5_+_9246018 0.26 ENSDART00000081769
ENSDART00000183189
susd1
sushi domain containing 1
chr1_+_58182400 0.26 ENSDART00000144784
si:ch211-15j1.1
si:ch211-15j1.1
chr14_-_29859067 0.26 ENSDART00000136380
sorbs2b
sorbin and SH3 domain containing 2b
chr1_-_47431453 0.26 ENSDART00000101104
gja5b
gap junction protein, alpha 5b
chr10_-_29272707 0.26 ENSDART00000022605
ENSDART00000184594
ENSDART00000185371
tmem126a
transmembrane protein 126A
chr1_-_17797802 0.26 ENSDART00000041215
sorbs2a
sorbin and SH3 domain containing 2a
chr20_+_47953047 0.25 ENSDART00000079734
hadhaa
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr3_+_1179601 0.25 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr4_-_16833518 0.25 ENSDART00000179867
ldhba
lactate dehydrogenase Ba
chr25_+_25766033 0.25 ENSDART00000103638
ENSDART00000039952
idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_+_58470287 0.24 ENSDART00000160245
ENSDART00000169945
si:ch73-236c18.7
si:ch73-236c18.7
chr23_-_28808480 0.24 ENSDART00000078167
dffa
DNA fragmentation factor, alpha polypeptide
chr22_+_19486711 0.23 ENSDART00000144389
ENSDART00000139256
ENSDART00000160855
si:dkey-78l4.10
si:dkey-78l4.10
chr16_+_54875530 0.23 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr1_+_58221372 0.23 ENSDART00000138467
si:dkey-222h21.10
si:dkey-222h21.10
chr12_-_47782623 0.23 ENSDART00000115742
selenou1b
selenoprotein U1b
chr24_+_81527 0.23 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr4_-_991043 0.23 ENSDART00000184706
naga
N-acetylgalactosaminidase, alpha
chr25_+_14694876 0.23 ENSDART00000050478
ENSDART00000188093
mpped2
metallophosphoesterase domain containing 2b
chr5_-_26330313 0.22 ENSDART00000148656
arvcfb
ARVCF, delta catenin family member b
chr6_-_25165693 0.22 ENSDART00000167259
znf326
zinc finger protein 326
chr16_-_24605969 0.22 ENSDART00000163305
ENSDART00000167121
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr8_-_25329967 0.21 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr20_-_47953524 0.21 ENSDART00000167986
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr1_+_23783349 0.21 ENSDART00000007531
slit2
slit homolog 2 (Drosophila)
chr1_-_59232267 0.21 ENSDART00000169658
ENSDART00000163257
akap8l
A kinase (PRKA) anchor protein 8-like
chr7_-_2090594 0.21 ENSDART00000183166
si:cabz01007802.1
si:cabz01007802.1
chr2_+_35880600 0.21 ENSDART00000004277
lamc1
laminin, gamma 1
chr10_+_20128267 0.21 ENSDART00000064615
dmtn
dematin actin binding protein
chr18_-_43866526 0.21 ENSDART00000111309
treh
trehalase (brush-border membrane glycoprotein)
chr14_+_34501245 0.21 ENSDART00000131424
lcp2b
lymphocyte cytosolic protein 2b
chr1_-_51720633 0.20 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr1_-_26664840 0.20 ENSDART00000102500
anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr12_+_22870372 0.20 ENSDART00000182264
ENSDART00000191789
ENSDART00000130594
ENSDART00000190433
afap1
actin filament associated protein 1
chr21_-_22317920 0.19 ENSDART00000191083
ENSDART00000108701
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr20_-_26937453 0.19 ENSDART00000139756
ftr97
finTRIM family, member 97
chr2_-_25143373 0.19 ENSDART00000160108
nceh1a
neutral cholesterol ester hydrolase 1a
chr7_+_59649399 0.19 ENSDART00000123520
ENSDART00000040771
rpl34
ribosomal protein L34
chr1_+_58312680 0.18 ENSDART00000138007
si:dkey-222h21.10
si:dkey-222h21.10
chr8_+_4745340 0.18 ENSDART00000182894
ufd1l
ubiquitin recognition factor in ER associated degradation 1
chr7_+_24520518 0.18 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr8_-_979735 0.18 ENSDART00000149612
znf366
zinc finger protein 366
chr13_-_36566260 0.17 ENSDART00000030133
synj2bp
synaptojanin 2 binding protein
chr5_+_43870389 0.17 ENSDART00000141002
zgc:112966
zgc:112966
chr3_-_7134113 0.17 ENSDART00000180849
BX005085.6

chr15_-_6946286 0.17 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr2_-_7666021 0.17 ENSDART00000180007
CABZ01021592.1

chr23_-_29394505 0.17 ENSDART00000017728
pgd
phosphogluconate dehydrogenase
chr20_-_32270866 0.17 ENSDART00000153140
armc2
armadillo repeat containing 2
chr14_+_15331486 0.17 ENSDART00000172077
ENSDART00000183370
ENSDART00000182467
SPINK2
si:dkey-203a12.5
si:dkey-203a12.4
si:dkey-203a12.5
chr11_+_6116503 0.17 ENSDART00000176170
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr11_+_11751006 0.17 ENSDART00000180372
ENSDART00000081018
jupa
junction plakoglobin a
chr8_+_25629941 0.17 ENSDART00000186925
wasa
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr3_+_40289418 0.17 ENSDART00000017304
cpsf4
cleavage and polyadenylation specific factor 4
chr1_+_58119117 0.17 ENSDART00000146788
si:ch211-15j1.5
si:ch211-15j1.5
chr19_+_40861853 0.17 ENSDART00000126470
zgc:85777
zgc:85777
chr1_+_15062 0.16 ENSDART00000169005
cep97
centrosomal protein 97
chr14_+_30413758 0.16 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr23_+_17437554 0.16 ENSDART00000184282
BX649300.3

chr6_+_39930825 0.16 ENSDART00000182352
ENSDART00000186643
ENSDART00000190513
ENSDART00000065092
ENSDART00000188645
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr3_-_19495814 0.16 ENSDART00000162248
CU571315.3

chr14_-_48103207 0.16 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr23_-_10696626 0.16 ENSDART00000177571
foxp1a
forkhead box P1a
chr24_-_2843107 0.16 ENSDART00000165290
cyb5a
cytochrome b5 type A (microsomal)
chr1_+_57145072 0.16 ENSDART00000152776
si:ch73-94k4.4
si:ch73-94k4.4
chr25_-_35106751 0.16 ENSDART00000180682
ENSDART00000073457
zgc:194989
zgc:194989
chr1_+_58139102 0.15 ENSDART00000134826
si:ch211-15j1.4
si:ch211-15j1.4
chr13_+_41819817 0.15 ENSDART00000185778
CABZ01066611.1

chr7_+_19374683 0.15 ENSDART00000162700
snrpf
small nuclear ribonucleoprotein polypeptide F
chr5_-_68927728 0.15 ENSDART00000132838
ank1a
ankyrin 1, erythrocytic a
chr2_-_56649883 0.15 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr12_-_34580988 0.15 ENSDART00000152926
bahcc1b
BAH domain and coiled-coil containing 1b
chr13_+_713941 0.15 ENSDART00000109737
cox15
cytochrome c oxidase assembly homolog 15 (yeast)
chr9_-_32684008 0.15 ENSDART00000041751
ercc1
excision repair cross-complementation group 1
chr4_-_75172216 0.15 ENSDART00000127522
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr16_-_19568388 0.14 ENSDART00000141616
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr20_+_27093042 0.14 ENSDART00000024595
ubr7
ubiquitin protein ligase E3 component n-recognin 7
chr16_-_5115993 0.14 ENSDART00000138654
ttk
ttk protein kinase
chr10_+_589501 0.14 ENSDART00000188415
LO018557.1

chr20_+_36806398 0.14 ENSDART00000153317
abracl
ABRA C-terminal like
chr24_+_9590188 0.14 ENSDART00000137092
si:dkey-96n2.1
si:dkey-96n2.1
chr3_+_22432069 0.14 ENSDART00000123054
wnk4b
WNK lysine deficient protein kinase 4b
chr21_+_15704556 0.14 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr4_+_47656992 0.14 ENSDART00000161148
znf1040
zinc finger protein 1040
chr16_+_7985886 0.14 ENSDART00000126041
ano10a
anoctamin 10a
chr10_+_11265387 0.14 ENSDART00000038888
hsdl2
hydroxysteroid dehydrogenase like 2
chr5_+_35786141 0.13 ENSDART00000022043
ENSDART00000127383
stard8
StAR-related lipid transfer (START) domain containing 8
chr15_+_34963316 0.13 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr7_+_59649746 0.13 ENSDART00000181067
rpl34
ribosomal protein L34
chr7_+_38267136 0.13 ENSDART00000173613
gpatch1
G patch domain containing 1
chr21_+_31253048 0.13 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr3_+_1749793 0.13 ENSDART00000149308
si:dkeyp-52c3.7
si:dkeyp-52c3.7
chr16_+_28602423 0.13 ENSDART00000182350
crot
carnitine O-octanoyltransferase
chr20_-_34164278 0.13 ENSDART00000153128
hmcn1
hemicentin 1
chr17_-_8976307 0.13 ENSDART00000092113
zranb1b
zinc finger, RAN-binding domain containing 1b
chr1_-_54063520 0.13 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr1_+_58303892 0.13 ENSDART00000147678
CR769768.1

chr14_+_30413312 0.13 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr14_-_29858883 0.13 ENSDART00000141034
sorbs2b
sorbin and SH3 domain containing 2b
chr10_+_24692076 0.13 ENSDART00000181600
tpte
transmembrane phosphatase with tensin homology
chr5_-_30984010 0.13 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr1_+_58290933 0.13 ENSDART00000140536
si:dkey-222h21.6
si:dkey-222h21.6
chr5_+_38276582 0.12 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_-_58868306 0.12 ENSDART00000166615
dnm2b
dynamin 2b
chr8_+_40275830 0.12 ENSDART00000164414
orai1a
ORAI calcium release-activated calcium modulator 1a
chr16_-_32128345 0.12 ENSDART00000102100
ENSDART00000137699
cnot3a
CCR4-NOT transcription complex, subunit 3a
chr11_-_29816429 0.12 ENSDART00000069132
cybb
cytochrome b-245, beta polypeptide (chronic granulomatous disease)
chr6_-_40429411 0.12 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr7_-_24046999 0.12 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr4_+_34119824 0.12 ENSDART00000165637
si:ch211-223g7.6
si:ch211-223g7.6
chr20_-_51656512 0.12 ENSDART00000129965
LO018154.1

chr7_-_19613388 0.12 ENSDART00000173664
si:ch211-212k18.13
si:ch211-212k18.13
chr7_-_40578733 0.12 ENSDART00000173926
ENSDART00000010035
dnajb6b
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr16_+_42830152 0.12 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr15_+_47618221 0.12 ENSDART00000168722
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
chr1_+_58260886 0.12 ENSDART00000110453
si:dkey-222h21.8
si:dkey-222h21.8
chr7_-_35393900 0.12 ENSDART00000173769
lpcat2
lysophosphatidylcholine acyltransferase 2
chr4_+_38981587 0.12 ENSDART00000142713
si:dkey-66k12.3
si:dkey-66k12.3
chr1_+_58312187 0.11 ENSDART00000142285
si:dkey-222h21.10
si:dkey-222h21.10
chr21_-_1640547 0.11 ENSDART00000151041
zgc:152948
zgc:152948
chr4_-_50926767 0.11 ENSDART00000183430
si:ch211-208f21.3
si:ch211-208f21.3
chr7_+_34297271 0.11 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_-_9648542 0.11 ENSDART00000172628
clcn1a
chloride channel, voltage-sensitive 1a
chr14_-_34700633 0.11 ENSDART00000150358
ablim3
actin binding LIM protein family, member 3
chr7_+_34296789 0.11 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr8_+_2530065 0.11 ENSDART00000063943
mrpl40
mitochondrial ribosomal protein L40
chr14_+_97017 0.11 ENSDART00000159300
ENSDART00000169523
mcm7
minichromosome maintenance complex component 7
chr15_-_1844048 0.11 ENSDART00000102410
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr23_+_17865554 0.11 ENSDART00000181009
ENSDART00000162822
naca
nascent polypeptide-associated complex alpha subunit
chr1_+_58150000 0.11 ENSDART00000137836
si:ch211-15j1.3
si:ch211-15j1.3
chr6_+_42475730 0.11 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr18_-_127558 0.11 ENSDART00000149556
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr11_-_44999858 0.11 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr8_-_2529878 0.10 ENSDART00000056767
acaa2
acetyl-CoA acyltransferase 2
chr24_-_11446156 0.10 ENSDART00000143921
ENSDART00000066778
acad11
acyl-CoA dehydrogenase family, member 11
chr19_-_32600823 0.10 ENSDART00000134149
ENSDART00000187858
zgc:91944
zgc:91944
chr8_+_8699085 0.10 ENSDART00000021209
uxt
ubiquitously-expressed, prefoldin-like chaperone
chr1_-_44314 0.10 ENSDART00000160050
tmem39a
transmembrane protein 39A
chr13_+_45980163 0.10 ENSDART00000074547
ENSDART00000005195
bsdc1
BSD domain containing 1
chr20_+_46513651 0.10 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr5_-_32890807 0.10 ENSDART00000007512
pole3
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr17_-_22137199 0.10 ENSDART00000089689
mrps5
mitochondrial ribosomal protein S5
chr7_-_8156169 0.10 ENSDART00000182960
ENSDART00000190184
ENSDART00000190885
ENSDART00000189867
ENSDART00000160836
si:cabz01030277.1
si:ch211-163c2.3
si:cabz01030277.1
si:ch211-163c2.3

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 1.2 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 0.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.2 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.1 0.8 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.2 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.7 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.4 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.1 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:1905133 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.9 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 1.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272) heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0030534 adult behavior(GO:0030534)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.2 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.0 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 1.2 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.8 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.8 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.2 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.2 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0016415 octanoyltransferase activity(GO:0016415)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling