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PRJNA207719: Tissue specific transcriptome profiling

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Results for nr2e3

Z-value: 0.85

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Transcription factors associated with nr2e3

Gene Symbol Gene ID Gene Info
nr2e3
ENSDARG00000045904 nuclear receptor subfamily 2, group E, member 3
nr2e3
ENSDARG00000113178 nuclear receptor subfamily 2, group E, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2e3dr11_v1_chr25_+_22274642_222746420.593.0e-01Click!

Activity profile of nr2e3 motif

Sorted Z-values of nr2e3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_47633438 0.72 ENSDART00000139096
si:ch211-251b21.1
si:ch211-251b21.1
chr13_+_27316934 0.69 ENSDART00000164533
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr3_-_34801041 0.60 ENSDART00000103043
nsfa
N-ethylmaleimide-sensitive factor a
chr6_+_38427357 0.54 ENSDART00000148678
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_-_10275320 0.51 ENSDART00000170078
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr2_+_47582681 0.48 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr3_-_28665291 0.48 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr11_-_1024483 0.45 ENSDART00000017551
slc6a1b
solute carrier family 6 (neurotransmitter transporter), member 1b
chr2_+_47582488 0.44 ENSDART00000149967
scg2b
secretogranin II (chromogranin C), b
chr24_-_29997145 0.44 ENSDART00000135094
palmdb
palmdelphin b
chr24_+_39158283 0.42 ENSDART00000053139
atp6v0cb
ATPase H+ transporting V0 subunit cb
chr8_+_3820134 0.42 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr13_+_38520927 0.42 ENSDART00000137299
ENSDART00000111080
adgrb3
adhesion G protein-coupled receptor B3
chr23_-_29502287 0.39 ENSDART00000141075
ENSDART00000053807
kif1b
kinesin family member 1B
chr20_-_28698172 0.37 ENSDART00000190635
sipa1l1
signal-induced proliferation-associated 1 like 1
chr21_+_25643880 0.37 ENSDART00000192392
ENSDART00000145091
tmem151a
transmembrane protein 151A
chr5_-_30588539 0.37 ENSDART00000086686
ENSDART00000159163
ENSDART00000142958
c2cd2l
c2cd2-like
chr4_+_4816695 0.37 ENSDART00000136962
slc13a4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr5_+_58397646 0.35 ENSDART00000180759
HEPACAM
hepatic and glial cell adhesion molecule
chr8_+_16025554 0.35 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr10_+_7182168 0.34 ENSDART00000172766
psd3l
pleckstrin and Sec7 domain containing 3, like
chr3_-_27868183 0.33 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr16_-_12914288 0.33 ENSDART00000184221
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr8_-_23416362 0.33 ENSDART00000063005
gpr173
G protein-coupled receptor 173
chr23_+_19564392 0.33 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr14_-_43000836 0.32 ENSDART00000162714
pcdh10b
protocadherin 10b
chr6_+_55277419 0.32 ENSDART00000083670
CABZ01041604.1

chr14_-_21618005 0.32 ENSDART00000043162
reep2
receptor accessory protein 2
chr5_-_28606916 0.31 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr22_+_34701848 0.31 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr20_+_34913069 0.31 ENSDART00000007584
snap25a
synaptosomal-associated protein, 25a
chr2_+_34767171 0.31 ENSDART00000145451
astn1
astrotactin 1
chr12_+_9320783 0.31 ENSDART00000152526
kcnh6b
potassium voltage-gated channel, subfamily H (eag-related), member 6b
chr13_+_27316632 0.30 ENSDART00000016121
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr7_+_13418812 0.30 ENSDART00000191905
ENSDART00000091567
dagla
diacylglycerol lipase, alpha
chr3_+_7617353 0.30 ENSDART00000165551
zgc:109949
zgc:109949
chr25_+_21829777 0.30 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr8_+_31941650 0.29 ENSDART00000138217
htr1aa
5-hydroxytryptamine (serotonin) receptor 1A a
chr5_+_36768674 0.29 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr22_-_3595439 0.29 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr20_-_31905968 0.29 ENSDART00000142806
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr10_-_7974155 0.29 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr3_+_15271943 0.29 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr24_+_2519761 0.29 ENSDART00000106619
nrn1a
neuritin 1a
chr14_-_46617228 0.28 ENSDART00000161010
ENSDART00000171054
prom1a
prominin 1a
chr6_+_38427570 0.28 ENSDART00000170612
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr12_-_37734973 0.28 ENSDART00000140353
sdk2b
sidekick cell adhesion molecule 2b
chr10_+_34685135 0.28 ENSDART00000184999
nbeaa
neurobeachin a
chr20_-_44576949 0.27 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr19_+_37925616 0.27 ENSDART00000148348
nxph1
neurexophilin 1
chr3_-_43821381 0.27 ENSDART00000166021
snn
stannin
chr15_-_34213898 0.27 ENSDART00000191945
ENSDART00000186089
etv1
ets variant 1
chr25_+_7670683 0.26 ENSDART00000040275
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr6_-_29143463 0.26 ENSDART00000087440
fam69ab
family with sequence similarity 69, member Ab
chr9_-_31596016 0.26 ENSDART00000142289
nalcn
sodium leak channel, non-selective
chr6_+_38381957 0.26 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr9_-_35334642 0.26 ENSDART00000157195
ncam2
neural cell adhesion molecule 2
chr14_-_2202652 0.26 ENSDART00000171316
si:dkey-262j3.7
si:dkey-262j3.7
chr4_-_5019113 0.26 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr10_+_7182423 0.25 ENSDART00000186788
psd3l
pleckstrin and Sec7 domain containing 3, like
chr2_+_50608099 0.25 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr14_-_2163454 0.25 ENSDART00000160123
ENSDART00000169653
pcdh2ab9
pcdh2ac
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr21_+_10076203 0.25 ENSDART00000190383
CABZ01043506.1

chr5_+_23242370 0.25 ENSDART00000051532
agtr2
angiotensin II receptor, type 2
chr9_+_17348745 0.25 ENSDART00000147488
slain1a
SLAIN motif family, member 1a
chr14_-_25599002 0.24 ENSDART00000040955
slc25a48
solute carrier family 25, member 48
chr6_-_52400896 0.24 ENSDART00000187624
mmp24
matrix metallopeptidase 24
chr14_-_46213571 0.23 ENSDART00000056734
setd7
SET domain containing (lysine methyltransferase) 7
chr12_+_26632448 0.23 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr7_+_50448478 0.23 ENSDART00000098815
serinc4
serine incorporator 4
chr8_+_29856013 0.23 ENSDART00000061981
ENSDART00000149610
hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
chr14_-_30724165 0.23 ENSDART00000020936
fibpa
fibroblast growth factor (acidic) intracellular binding protein a
chr25_-_7686201 0.23 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
si:ch211-286c4.6
chr24_-_24163201 0.23 ENSDART00000140170
map7d2b
MAP7 domain containing 2b
chr1_+_22851745 0.23 ENSDART00000138235
ENSDART00000016488
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr10_+_45128375 0.22 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr9_+_42063906 0.22 ENSDART00000048893
pcbp3
poly(rC) binding protein 3
chr24_-_18809433 0.22 ENSDART00000152009
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr16_+_5774977 0.22 ENSDART00000134202
ccka
cholecystokinin a
chr19_+_42231431 0.21 ENSDART00000102698
jtb
jumping translocation breakpoint
chr2_-_37043540 0.21 ENSDART00000131834
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr2_-_8017579 0.21 ENSDART00000040209
ephb3a
eph receptor B3a
chr22_+_20208185 0.21 ENSDART00000142748
si:dkey-110c1.7
si:dkey-110c1.7
chr9_-_3671911 0.21 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr13_+_16522608 0.21 ENSDART00000182838
ENSDART00000143200
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr7_-_46781614 0.21 ENSDART00000173891
tshz3b
teashirt zinc finger homeobox 3b
chr1_-_42778510 0.21 ENSDART00000190172
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr19_-_5812319 0.21 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr10_+_21776911 0.21 ENSDART00000163077
ENSDART00000186093
pcdh1g22
protocadherin 1 gamma 22
chr20_-_909953 0.21 ENSDART00000011283
cnr1
cannabinoid receptor 1
chr18_-_7342950 0.21 ENSDART00000081356
caps2
calcyphosine 2
chr10_+_24504464 0.21 ENSDART00000141387
mtus2a
microtubule associated tumor suppressor candidate 2a
chr12_+_42436328 0.21 ENSDART00000167324
ebf3a
early B cell factor 3a
chr9_-_35557397 0.20 ENSDART00000100681
ncam2
neural cell adhesion molecule 2
chr8_-_14080534 0.20 ENSDART00000042867
dedd
death effector domain containing
chr3_+_17456428 0.20 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
si:ch211-210g13.5
chr17_-_3986236 0.20 ENSDART00000188794
ENSDART00000160830
PLCB1
si:ch1073-140o9.2
chr16_-_13004166 0.20 ENSDART00000133735
cacng7b
calcium channel, voltage-dependent, gamma subunit 7b
chr12_-_10705916 0.20 ENSDART00000164038
FO704786.1

chr24_+_15020402 0.20 ENSDART00000148102
dok6
docking protein 6
chr24_+_15277216 0.20 ENSDART00000081449
socs6a
suppressor of cytokine signaling 6a
chr17_+_51499789 0.20 ENSDART00000187701
CABZ01067581.1

chr20_-_15132151 0.20 ENSDART00000063884
si:dkey-239i20.4
si:dkey-239i20.4
chr25_-_12203952 0.20 ENSDART00000158204
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr18_-_38087875 0.20 ENSDART00000111301
luzp2
leucine zipper protein 2
chr10_+_2981090 0.19 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr6_-_51386656 0.19 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
ptprt
protein tyrosine phosphatase, receptor type, t
chr12_+_26471712 0.19 ENSDART00000162115
ndel1a
nudE neurodevelopment protein 1-like 1a
chr20_+_19238382 0.19 ENSDART00000136757
fndc4a
fibronectin type III domain containing 4a
chr21_+_32332616 0.19 ENSDART00000154105
si:ch211-247j9.1
si:ch211-247j9.1
chr4_+_68476490 0.19 ENSDART00000168543
si:dkey-237g15.2
si:dkey-237g15.2
chr22_-_17574511 0.19 ENSDART00000181496
pip5k1ca
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr3_-_43821191 0.19 ENSDART00000186816
snn
stannin
chr5_-_33607062 0.19 ENSDART00000048350
si:dkey-34e4.1
si:dkey-34e4.1
chr10_+_33902264 0.19 ENSDART00000193793
fryb
furry homolog b (Drosophila)
chr9_-_6661657 0.19 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
pou3f3a
POU class 3 homeobox 3a
chr17_-_44247707 0.19 ENSDART00000126097
otx2b
orthodenticle homeobox 2b
chr6_-_12314475 0.19 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr23_-_17657348 0.18 ENSDART00000054736
bhlhe23
basic helix-loop-helix family, member e23
chr22_-_18022416 0.18 ENSDART00000141563
ncanb
neurocan b
chr9_+_30720048 0.18 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr9_-_12034444 0.18 ENSDART00000038651
znf804a
zinc finger protein 804A
chr1_-_54997746 0.18 ENSDART00000152666
slc25a23a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr1_+_32521469 0.18 ENSDART00000113818
ENSDART00000152580
nlgn4a
neuroligin 4a
chr7_-_35126374 0.18 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr9_+_6079528 0.18 ENSDART00000142167
st6gal2a
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr20_-_34453623 0.18 ENSDART00000005609
kifap3a
kinesin-associated protein 3a
chr6_+_37754763 0.18 ENSDART00000110770
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr9_-_40935934 0.18 ENSDART00000155604
C2orf88
Small membrane A-kinase anchor protein
chr4_+_23223881 0.18 ENSDART00000133056
ENSDART00000089126
trhde.1
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr18_+_50276653 0.18 ENSDART00000192120
si:dkey-105e17.1
si:dkey-105e17.1
chr15_+_7992906 0.18 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr5_-_10946232 0.18 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr15_-_14486534 0.17 ENSDART00000179368
numbl
numb homolog (Drosophila)-like
chr20_-_50239406 0.17 ENSDART00000128053
tmem121ab
transmembrane protein 121Ab
chr9_-_16133263 0.17 ENSDART00000077187
myo1b
myosin IB
chr18_-_8857137 0.17 ENSDART00000126331
prrt4
proline-rich transmembrane protein 4
chr23_-_28294763 0.17 ENSDART00000139537
znf385a
zinc finger protein 385A
chr18_-_38088099 0.17 ENSDART00000146120
luzp2
leucine zipper protein 2
chr6_-_35310224 0.17 ENSDART00000148997
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr11_-_37995501 0.17 ENSDART00000192096
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr5_-_43959972 0.17 ENSDART00000180517
si:ch211-204c21.1
si:ch211-204c21.1
chr12_+_25600685 0.17 ENSDART00000077157
six3b
SIX homeobox 3b
chr22_+_31930650 0.17 ENSDART00000092090
dock3
dedicator of cytokinesis 3
chr8_-_29851706 0.17 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr7_+_63325819 0.17 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b
chr20_-_34868814 0.17 ENSDART00000153049
stmn4
stathmin-like 4
chr18_-_23875219 0.17 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr9_+_17983463 0.16 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr11_+_13071645 0.16 ENSDART00000162259
zfyve9b
zinc finger, FYVE domain containing 9b
chr8_-_15398760 0.16 ENSDART00000162011
agbl4
ATP/GTP binding protein-like 4
chr12_+_32368574 0.16 ENSDART00000086389
ANKFN1
si:ch211-277e21.2
chr18_-_14734678 0.16 ENSDART00000142462
tshz3a
teashirt zinc finger homeobox 3a
chr18_-_6824518 0.16 ENSDART00000141132
ppp6r2b
protein phosphatase 6, regulatory subunit 2b
chr9_+_17982737 0.16 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr16_-_9383629 0.16 ENSDART00000084264
ENSDART00000166958
adcy2a
adenylate cyclase 2a
chr12_+_2631711 0.16 ENSDART00000114209
gdf10b
growth differentiation factor 10b
chr23_+_2778813 0.16 ENSDART00000142621
top1
DNA topoisomerase I
chr18_-_23874929 0.16 ENSDART00000134910
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr6_+_32338334 0.16 ENSDART00000065149
dock7
dedicator of cytokinesis 7
chr10_+_15255198 0.16 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr5_+_32009080 0.16 ENSDART00000186885
scai
suppressor of cancer cell invasion
chr10_+_15255012 0.16 ENSDART00000023766
vldlr
very low density lipoprotein receptor
chr18_-_7382003 0.16 ENSDART00000101238
ENSDART00000178284
bbs10
Bardet-Biedl syndrome 10
chr20_+_32523576 0.16 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr6_-_13408680 0.16 ENSDART00000151566
fmnl2b
formin-like 2b
chr14_-_2036604 0.16 ENSDART00000192446
BX005294.2

chr4_-_63923523 0.16 ENSDART00000144330
si:dkey-179k24.1
si:dkey-179k24.1
chr7_-_5487593 0.15 ENSDART00000136594
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr14_+_45028062 0.15 ENSDART00000184717
ENSDART00000185481
ATP8A1
ATPase phospholipid transporting 8A1
chr4_-_5077158 0.15 ENSDART00000155915
ahcyl2
adenosylhomocysteinase-like 2
chr25_-_7925019 0.15 ENSDART00000183309
glcea
glucuronic acid epimerase a
chr20_-_28349144 0.15 ENSDART00000179690
ENSDART00000188059
ino80
INO80 complex subunit
chr12_+_31744217 0.15 ENSDART00000190361
RNF157
si:dkey-49c17.3
chr25_+_33033633 0.15 ENSDART00000192336
tln2b
talin 2b
chr1_-_36151377 0.15 ENSDART00000037516
znf827
zinc finger protein 827
chr11_-_28911172 0.15 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr18_+_37120096 0.15 ENSDART00000147385
sipa1l3
signal-induced proliferation-associated 1 like 3
chr10_-_7909839 0.15 ENSDART00000139868
slc35e4
solute carrier family 35, member E4
chr10_+_22782522 0.15 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chrM_+_8894 0.15 ENSDART00000093611
mt-atp8
ATP synthase 8, mitochondrial
chr8_+_13364950 0.15 ENSDART00000159760
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr21_+_34976600 0.15 ENSDART00000191672
ENSDART00000139635
rbm11
RNA binding motif protein 11
chr6_+_39222598 0.15 ENSDART00000154991
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr20_-_31252809 0.14 ENSDART00000137236
hpcal1
hippocalcin-like 1
chr5_+_38263240 0.14 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr12_+_9320446 0.14 ENSDART00000112507
kcnh6b
potassium voltage-gated channel, subfamily H (eag-related), member 6b
chr5_+_19712011 0.14 ENSDART00000131924
fam222a
family with sequence similarity 222, member A
chr7_+_21752168 0.14 ENSDART00000173641
kdm6ba
lysine (K)-specific demethylase 6B, a
chr24_+_37080771 0.14 ENSDART00000159942
kcnc3b
potassium voltage-gated channel, Shaw-related subfamily, member 3b
chr21_+_10794914 0.14 ENSDART00000084035
znf532
zinc finger protein 532
chr8_-_1838315 0.14 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr6_-_46403475 0.14 ENSDART00000154148
camk1a
calcium/calmodulin-dependent protein kinase Ia
chr22_+_1049367 0.14 ENSDART00000065380
camk1ga
calcium/calmodulin-dependent protein kinase IGa
chr20_+_29690901 0.14 ENSDART00000142669
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr21_-_7691293 0.14 ENSDART00000093339
pde8b
phosphodiesterase 8B
chr9_-_4506819 0.14 ENSDART00000113975
kcnj3a
potassium inwardly-rectifying channel, subfamily J, member 3a
chr9_-_25444091 0.14 ENSDART00000002428
acvr2aa
activin A receptor type 2Aa
chr3_+_46425262 0.13 ENSDART00000153690
sc:d0202
sc:d0202
chr18_+_40355408 0.13 ENSDART00000167134
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2e3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0048913 Golgi vesicle docking(GO:0048211) anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.1 0.4 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.1 0.3 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.1 0.3 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.3 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 0.2 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 0.2 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.1 GO:0035046 pronuclear migration(GO:0035046)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.2 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.1 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0046661 male sex differentiation(GO:0046661)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.3 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.1 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.0 1.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) multi-organism behavior(GO:0051705)
0.0 0.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.0 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.1 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.0 GO:0060137 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.0 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.0 0.1 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0 1.0 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.3 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.4 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.4 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 1.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 0.2 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.0 0.4 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation