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PRJNA207719: Tissue specific transcriptome profiling

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Results for nr2f1b+nr2f5

Z-value: 0.59

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Transcription factors associated with nr2f1b+nr2f5

Gene Symbol Gene ID Gene Info
nr2f1b
ENSDARG00000017168 nuclear receptor subfamily 2, group F, member 1b
nr2f5
ENSDARG00000033172 nuclear receptor subfamily 2, group F, member 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f1bdr11_v1_chr10_+_43797130_43797130-0.961.0e-02Click!
nr2f5dr11_v1_chr16_+_46294337_46294337-0.059.4e-01Click!

Activity profile of nr2f1b+nr2f5 motif

Sorted Z-values of nr2f1b+nr2f5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_6010177 0.58 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr18_+_8340886 0.51 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr7_+_4474880 0.49 ENSDART00000143528
si:dkey-83f18.14
si:dkey-83f18.14
chr3_-_19517462 0.49 ENSDART00000162027
CU571315.2

chr20_+_53577502 0.42 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr22_+_344763 0.39 ENSDART00000181934
CU914780.1

chr21_+_28445052 0.37 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr19_+_8606883 0.37 ENSDART00000054469
ENSDART00000185264
s100a10a
S100 calcium binding protein A10a
chr13_-_13754091 0.36 ENSDART00000131255
ky
kyphoscoliosis peptidase
chr18_-_49283058 0.34 ENSDART00000076554
si:zfos-464b6.2
si:zfos-464b6.2
chr17_+_5351922 0.32 ENSDART00000105394
runx2a
runt-related transcription factor 2a
chr18_-_11729 0.31 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr19_+_7938121 0.30 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
si:dkey-266f7.5
chr5_+_64856666 0.30 ENSDART00000050863
zgc:101858
zgc:101858
chr14_+_34558480 0.30 ENSDART00000075170
pttg1
pituitary tumor-transforming 1
chr13_+_22249636 0.29 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr2_+_52847049 0.29 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr24_+_42149453 0.26 ENSDART00000128766
serpinb1l3
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr20_+_25581627 0.25 ENSDART00000030229
cyp2p9
cytochrome P450, family 2, subfamily P, polypeptide 9
chr25_+_1549838 0.25 ENSDART00000115001
avpr1aa
arginine vasopressin receptor 1Aa
chr19_+_26828502 0.24 ENSDART00000183654
ENSDART00000126006
ENSDART00000185341
FP085398.1

chr10_-_76352 0.24 ENSDART00000186560
ENSDART00000144722
dyrk1aa
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr22_+_37888249 0.24 ENSDART00000076082
fetub
fetuin B
chr1_+_56229674 0.23 ENSDART00000127714
c3a.2
complement component c3a, duplicate 2
chr1_+_144284 0.22 ENSDART00000064061
prozb
protein Z, vitamin K-dependent plasma glycoprotein b
chr15_-_41756454 0.21 ENSDART00000139498
ENSDART00000099302
ftr72
finTRIM family, member 72
chr15_+_22394074 0.21 ENSDART00000109931
oafa
OAF homolog a (Drosophila)
chr4_-_13613148 0.21 ENSDART00000067164
ENSDART00000111247
irf5
interferon regulatory factor 5
chr24_+_42149296 0.21 ENSDART00000154231
serpinb1l3
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr15_+_34933552 0.19 ENSDART00000155368
zgc:66024
zgc:66024
chr4_-_77120928 0.19 ENSDART00000174154
CU467646.1

chr20_-_16906623 0.19 ENSDART00000012859
ENSDART00000171628
psma6b
proteasome subunit alpha 6b
chr5_-_8910703 0.19 ENSDART00000097221
adamts12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr2_+_58841181 0.19 ENSDART00000164102
cirbpa
cold inducible RNA binding protein a
chr24_+_37700259 0.18 ENSDART00000066556
zmp:0000000624
zmp:0000000624
chr8_+_23711842 0.18 ENSDART00000128783
ppardb
peroxisome proliferator-activated receptor delta b
chr13_+_50778187 0.18 ENSDART00000159597
dntt
deoxynucleotidyltransferase, terminal
chr8_-_13419049 0.17 ENSDART00000133656
pimr101
Pim proto-oncogene, serine/threonine kinase, related 101
chr8_-_13471916 0.17 ENSDART00000146558
pimr105
Pim proto-oncogene, serine/threonine kinase, related 105
chr1_-_20824411 0.17 ENSDART00000182810
tll1
tolloid-like 1
chr24_-_22003031 0.17 ENSDART00000133627
si:rp71-1f1.5
si:rp71-1f1.5
chr24_-_22015751 0.16 ENSDART00000147055
si:rp71-1f1.6
si:rp71-1f1.6
chr1_-_18772241 0.16 ENSDART00000147645
ENSDART00000133194
ENSDART00000147525
ENSDART00000191493
tbc1d1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr8_-_13454281 0.15 ENSDART00000141959
CR354547.2

chr4_+_73215536 0.15 ENSDART00000174290
LO018260.2
Danio rerio protein NLRC3-like (LOC101883187), mRNA.
chr24_+_42127983 0.15 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr24_+_42132962 0.14 ENSDART00000187739
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr5_-_25084318 0.14 ENSDART00000089339
dph7
diphthamide biosynthesis 7
chr9_-_9980704 0.14 ENSDART00000130243
ENSDART00000193475
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr2_-_5502256 0.14 ENSDART00000193037
saga
S-antigen; retina and pineal gland (arrestin) a
chr16_+_20895904 0.14 ENSDART00000052662
hoxa13b
homeobox A13b
chr13_-_50546634 0.14 ENSDART00000192127
CU570781.2

chr8_-_13442871 0.13 ENSDART00000144887
pimr106
Pim proto-oncogene, serine/threonine kinase, related 106
chr8_-_13486258 0.13 ENSDART00000137459
pimr104
Pim proto-oncogene, serine/threonine kinase, related 104
chr4_+_9011448 0.13 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr22_-_26834043 0.13 ENSDART00000087202
si:dkey-44g23.5
si:dkey-44g23.5
chr19_+_7506380 0.12 ENSDART00000182837
prcc
papillary renal cell carcinoma (translocation-associated)
chr17_+_389218 0.12 ENSDART00000162898
si:rp71-62i8.1
si:rp71-62i8.1
chr7_+_27251376 0.12 ENSDART00000173521
ENSDART00000173962
sox6
SRY (sex determining region Y)-box 6
chr5_+_54400971 0.11 ENSDART00000169695
bspry
B-box and SPRY domain containing
chr1_-_55785722 0.10 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr14_+_46118834 0.10 ENSDART00000124417
ENSDART00000017785
naa15a
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a
chr4_+_1530287 0.10 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr22_+_18316144 0.10 ENSDART00000137985
gatad2ab
GATA zinc finger domain containing 2Ab
chr21_+_5882300 0.09 ENSDART00000165065
uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr18_-_6975175 0.09 ENSDART00000134194
si:dkey-266m15.6
si:dkey-266m15.6
chr2_-_16449504 0.09 ENSDART00000144801
atr
ATR serine/threonine kinase
chr17_+_14711765 0.09 ENSDART00000012889
cx28.6
connexin 28.6
chr7_-_2039060 0.08 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr14_+_2487672 0.07 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr2_+_21605547 0.06 ENSDART00000112014
mplkip
M-phase specific PLK1 interacting protein
chr4_+_9011825 0.06 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr15_-_34933560 0.05 ENSDART00000006288
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr23_+_25822742 0.05 ENSDART00000184436
r3hdml
R3H domain containing-like
chr17_-_53282539 0.05 ENSDART00000164953
FO704905.1

chr24_+_42117231 0.05 ENSDART00000067734
snx16
sorting nexin 16
chr4_+_76441823 0.04 ENSDART00000163932
si:dkey-16p6.1
si:dkey-16p6.1
chr9_+_500052 0.04 ENSDART00000166707
CU984600.1

chr8_-_13428740 0.04 ENSDART00000131826
CR354547.3

chr10_-_29831944 0.04 ENSDART00000063923
ENSDART00000136264
zpr1
ZPR1 zinc finger
chr5_-_40292299 0.04 ENSDART00000097525
snx18a
sorting nexin 18a
chr4_+_1722899 0.03 ENSDART00000021139
fgfr1op2
FGFR1 oncogene partner 2
chr2_+_33382648 0.03 ENSDART00000137207
ENSDART00000098831
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_+_41917499 0.03 ENSDART00000028673
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr18_+_7073130 0.03 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr15_+_27364394 0.02 ENSDART00000122101
tbx2b
T-box 2b
chr2_+_2904080 0.02 ENSDART00000110416
eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr1_-_40132831 0.01 ENSDART00000135647
si:ch211-113e8.10
si:ch211-113e8.10
chr24_-_21991770 0.01 ENSDART00000147296
si:rp71-1f1.4
si:rp71-1f1.4
chr1_-_26544268 0.01 ENSDART00000152117
si:ch211-202n12.2
si:ch211-202n12.2
chr7_-_26446726 0.00 ENSDART00000173607
zgc:172079
zgc:172079

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f1b+nr2f5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.1 0.4 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 0.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.5 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0033046 negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway