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PRJNA207719: Tissue specific transcriptome profiling

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Results for nr2f6a+nr2f6b

Z-value: 0.27

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Transcription factors associated with nr2f6a+nr2f6b

Gene Symbol Gene ID Gene Info
nr2f6b
ENSDARG00000003165 nuclear receptor subfamily 2, group F, member 6b
nr2f6a
ENSDARG00000003607 nuclear receptor subfamily 2, group F, member 6a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f6adr11_v1_chr2_+_24374669_243746690.875.4e-02Click!
nr2f6bdr11_v1_chr11_+_6116096_6116096-0.405.1e-01Click!

Activity profile of nr2f6a+nr2f6b motif

Sorted Z-values of nr2f6a+nr2f6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_45128375 0.28 ENSDART00000164805
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr22_-_11833317 0.22 ENSDART00000125423
ENSDART00000000192
ptpn4b
protein tyrosine phosphatase, non-receptor type 4b
chr24_-_21172122 0.21 ENSDART00000154259
atp6v1ab
ATPase H+ transporting V1 subunit Ab
chr25_-_19420949 0.18 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr10_+_20128267 0.18 ENSDART00000064615
dmtn
dematin actin binding protein
chr1_+_58353661 0.17 ENSDART00000140074
si:dkey-222h21.2
si:dkey-222h21.2
chr24_+_39137001 0.17 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr1_+_25848231 0.16 ENSDART00000027973
fabp2
fatty acid binding protein 2, intestinal
chr19_+_2275019 0.16 ENSDART00000136138
itgb8
integrin, beta 8
chr23_+_30730121 0.16 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr23_-_45504991 0.16 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr18_-_12957451 0.15 ENSDART00000140403
srgap1a
SLIT-ROBO Rho GTPase activating protein 1a
chr24_-_1021318 0.14 ENSDART00000181403
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr18_+_16330025 0.14 ENSDART00000142353
nts
neurotensin
chr18_+_31410652 0.13 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr18_+_27515640 0.13 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr15_+_47386939 0.13 ENSDART00000128224
FO904873.1

chr21_+_1119046 0.13 ENSDART00000184678
CABZ01088049.1

chr22_-_3595439 0.12 ENSDART00000083308
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr18_-_1185772 0.12 ENSDART00000143245
nptnb
neuroplastin b
chr9_-_25255490 0.10 ENSDART00000141502
htr2aa
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr8_+_36803415 0.10 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr5_-_26330313 0.09 ENSDART00000148656
arvcfb
ARVCF, delta catenin family member b
chr9_-_37613792 0.09 ENSDART00000138345
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr7_+_25000060 0.09 ENSDART00000039265
ENSDART00000141814
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr25_+_15647993 0.08 ENSDART00000186578
ENSDART00000031828
spon1b
spondin 1b
chr5_+_49744713 0.08 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr2_-_56649883 0.08 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr13_-_37127970 0.08 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr24_+_39034090 0.07 ENSDART00000185763
capn15
calpain 15
chr6_+_40952031 0.07 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr18_-_18850302 0.07 ENSDART00000131965
ENSDART00000167624
tgm2l
transglutaminase 2, like
chr12_+_46708920 0.06 ENSDART00000153089
exoc7
exocyst complex component 7
chr25_+_20119466 0.06 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr12_+_26670778 0.06 ENSDART00000144355
arhgap12b
Rho GTPase activating protein 12b
chr2_-_41571454 0.06 ENSDART00000022643
znf622
zinc finger protein 622
chr8_+_8012570 0.06 ENSDART00000183429
si:ch211-169p10.1
si:ch211-169p10.1
chr11_-_44999858 0.06 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr4_-_75172216 0.06 ENSDART00000127522
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr23_-_42810664 0.05 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr11_+_30729745 0.05 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr25_+_18587338 0.05 ENSDART00000180287
met
MET proto-oncogene, receptor tyrosine kinase
chr12_+_49125510 0.04 ENSDART00000185804
FO704607.1

chr17_+_23926796 0.04 ENSDART00000021177
pex13
peroxisomal biogenesis factor 13
chr2_-_22659450 0.04 ENSDART00000115025
thap4
THAP domain containing 4
chr24_-_7587401 0.04 ENSDART00000093163
galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr23_+_36340520 0.04 ENSDART00000011201
copz1
coatomer protein complex, subunit zeta 1
chr23_-_46126444 0.04 ENSDART00000030004
CABZ01071903.1

chr22_-_16997887 0.04 ENSDART00000138233
nfia
nuclear factor I/A
chr19_-_3056235 0.04 ENSDART00000137020
bop1
block of proliferation 1
chr23_+_2914577 0.04 ENSDART00000184897
DHX35
zgc:158828
chr7_-_36113098 0.03 ENSDART00000064913
fto
fat mass and obesity associated
chr25_+_22017182 0.03 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr7_-_24520866 0.03 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr18_-_7399767 0.03 ENSDART00000181689
si:dkey-30c15.13
si:dkey-30c15.13
chr22_-_16997475 0.03 ENSDART00000090237
nfia
nuclear factor I/A
chr3_+_1179601 0.03 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr9_+_32859967 0.03 ENSDART00000168992
si:dkey-145p14.5
si:dkey-145p14.5
chr9_+_34380299 0.03 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr1_+_58182400 0.03 ENSDART00000144784
si:ch211-15j1.1
si:ch211-15j1.1
chr23_-_21797517 0.02 ENSDART00000110041
lrrc38a
leucine rich repeat containing 38a
chr4_-_858434 0.02 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr1_+_58303892 0.02 ENSDART00000147678
CR769768.1

chr8_-_4097722 0.02 ENSDART00000135006
cux2b
cut-like homeobox 2b
chr1_+_23783349 0.02 ENSDART00000007531
slit2
slit homolog 2 (Drosophila)
chr13_+_45980163 0.02 ENSDART00000074547
ENSDART00000005195
bsdc1
BSD domain containing 1
chr17_+_450956 0.02 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr12_+_48681601 0.02 ENSDART00000187831
uros
uroporphyrinogen III synthase
chr7_+_48297842 0.02 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr6_+_40775800 0.01 ENSDART00000085090
si:ch211-157b11.8
si:ch211-157b11.8
chr15_+_47618221 0.01 ENSDART00000168722
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
chr22_-_16997246 0.01 ENSDART00000090242
nfia
nuclear factor I/A
chr17_-_25303486 0.01 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr23_+_27912079 0.01 ENSDART00000171859
BX539336.1

chr12_-_31457301 0.01 ENSDART00000043887
ENSDART00000148603
acsl5
acyl-CoA synthetase long chain family member 5
chr1_+_58221372 0.01 ENSDART00000138467
si:dkey-222h21.10
si:dkey-222h21.10
chr23_+_44634187 0.01 ENSDART00000143688
si:ch73-265d7.2
si:ch73-265d7.2
chr1_+_58442694 0.01 ENSDART00000160897
zgc:194906
zgc:194906
chr21_-_44512893 0.01 ENSDART00000166853
zgc:136410
zgc:136410
chr17_-_6954719 0.01 ENSDART00000188180
zbtb24
zinc finger and BTB domain containing 24
chr1_-_51720633 0.00 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr1_+_58260886 0.00 ENSDART00000110453
si:dkey-222h21.8
si:dkey-222h21.8
chr9_-_28990649 0.00 ENSDART00000078823
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr7_+_38267136 0.00 ENSDART00000173613
gpatch1
G patch domain containing 1
chr3_-_41292275 0.00 ENSDART00000144088
sdk1a
sidekick cell adhesion molecule 1a
chr4_-_16451375 0.00 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr8_+_8699085 0.00 ENSDART00000021209
uxt
ubiquitously-expressed, prefoldin-like chaperone
chr9_-_15208129 0.00 ENSDART00000137043
ENSDART00000131512
pard3bb
par-3 family cell polarity regulator beta b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f6a+nr2f6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.0 GO:0042245 RNA repair(GO:0042245)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.0 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions