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PRJNA207719: Tissue specific transcriptome profiling

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Results for nr4a3

Z-value: 0.91

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Transcription factors associated with nr4a3

Gene Symbol Gene ID Gene Info
ENSDARG00000055854 nuclear receptor subfamily 4, group A, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a3dr11_v1_chr16_+_27345383_27345383-0.385.2e-01Click!

Activity profile of nr4a3 motif

Sorted Z-values of nr4a3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_19220459 0.75 ENSDART00000163070
si:dkey-21e2.7
chr18_+_38321039 0.70 ENSDART00000132534
ENSDART00000111260
ENSDART00000192806
ALX homeobox 4b
chr2_-_42234484 0.60 ENSDART00000132617
ENSDART00000136690
ENSDART00000141358
apolipoprotein M
chr15_-_21239416 0.56 ENSDART00000155787
si:dkey-105h12.2
chr10_-_32524771 0.53 ENSDART00000066793
diacylglycerol O-acyltransferase 2
chr16_-_31675669 0.52 ENSDART00000168848
ENSDART00000158331
complement component 1, r subcomponent
chr12_+_14084291 0.52 ENSDART00000189734
si:ch211-217a12.1
chr7_+_35068036 0.51 ENSDART00000022139
zgc:136461
chr19_+_11214007 0.50 ENSDART00000127362
si:ch73-109i22.2
chr16_-_31976269 0.50 ENSDART00000139664
serine/threonine/tyrosine kinase 1
chr8_+_1170015 0.49 ENSDART00000081457
ENSDART00000164116
chemokine (C-C motif) ligand 27a
chr22_-_24818066 0.48 ENSDART00000143443
vitellogenin 6
chr5_-_14509137 0.48 ENSDART00000180742
si:ch211-244o22.2
chr9_-_22822084 0.48 ENSDART00000142020
nebulin
chr9_+_35077546 0.48 ENSDART00000142688
si:dkey-192g7.3
chr9_+_23770666 0.46 ENSDART00000182493
si:ch211-219a4.3
chr9_-_22821901 0.46 ENSDART00000101711
nebulin
chr12_+_46634736 0.45 ENSDART00000008009
tripartite motif containing 16
chr1_-_43915423 0.45 ENSDART00000181915
ENSDART00000113673
secretory calcium-binding phosphoprotein 5
chr21_-_22724980 0.44 ENSDART00000035469
complement component 1, q subcomponent, A chain
chr7_+_13988075 0.43 ENSDART00000186812
furin (paired basic amino acid cleaving enzyme) a
chr15_-_108414 0.42 ENSDART00000170044
apolipoprotein A-Ib
chr3_+_55100045 0.42 ENSDART00000113098
hemoglobin, alpha adult 1
chr3_+_12816362 0.41 ENSDART00000163743
ENSDART00000170788
cytochrome P450, family 2, subfamily K, polypeptide 6
chr25_+_29160102 0.40 ENSDART00000162854
pyruvate kinase M1/2b
chr3_+_31662126 0.40 ENSDART00000113441
myosin, light chain kinase 5
chr22_-_14262115 0.39 ENSDART00000168264
si:ch211-246m6.5
chr7_-_26924903 0.39 ENSDART00000124363
ALX homeobox 4a
chr1_-_52431220 0.39 ENSDART00000111256
zgc:194101
chr20_+_37794633 0.38 ENSDART00000022060
activating transcription factor 3
chr23_+_44614056 0.38 ENSDART00000188379
enolase 3, (beta, muscle)
chr4_+_76752707 0.38 ENSDART00000082121
membrane-spanning 4-domains, subfamily A, member 17A.4
chr9_+_23772516 0.37 ENSDART00000183126
si:ch211-219a4.3
chr1_+_1789357 0.37 ENSDART00000006449
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2
chr19_-_35439237 0.37 ENSDART00000145883
anillin, actin binding protein
chr5_+_29831235 0.34 ENSDART00000109660
F11 receptor, tandem duplicate 1
chr19_-_7110617 0.34 ENSDART00000104838
proteasome subunit beta 8A
chr14_+_21905492 0.34 ENSDART00000054437
TBC1 domain family, member 10C
chr1_-_39859626 0.32 ENSDART00000053763
dCMP deaminase
chr20_-_26937453 0.32 ENSDART00000139756
finTRIM family, member 97
chr20_+_36806398 0.32 ENSDART00000153317
ABRA C-terminal like
chr24_-_26820698 0.32 ENSDART00000147788
fibronectin type III domain containing 3Bb
chr22_+_987788 0.31 ENSDART00000149486
differentially expressed in FDCP 6b homolog (mouse)
chr1_-_52498146 0.31 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr3_-_33970431 0.31 ENSDART00000151313
ighj2-4
chr16_+_23913943 0.30 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr8_-_22542467 0.30 ENSDART00000182588
ENSDART00000134542
cold shock domain containing E1, RNA-binding
chr12_-_4185554 0.30 ENSDART00000152313
si:dkey-32n7.7
chr15_+_3246475 0.29 ENSDART00000189565

chr4_-_77135076 0.29 ENSDART00000174184
zgc:173770
chr18_-_40708537 0.29 ENSDART00000077577
si:ch211-132b12.8
chr3_+_12848123 0.28 ENSDART00000166689
si:ch211-8c17.4
chr4_-_77130289 0.28 ENSDART00000174380

chr5_-_30984010 0.28 ENSDART00000182367
spinster homolog 3 (Drosophila)
chr3_+_3454610 0.28 ENSDART00000024900
zgc:165453
chr11_+_42587900 0.27 ENSDART00000167529
ankyrin repeat and SOCS box containing 14a
chr4_-_77116266 0.27 ENSDART00000174249

chr25_+_9003230 0.27 ENSDART00000180330
ENSDART00000142917
recombination activating gene 1
chr21_-_5879897 0.26 ENSDART00000184034
ribosomal protein L35
chr10_-_26202766 0.26 ENSDART00000136393
FH2 domain containing 3
chr22_+_6254194 0.26 ENSDART00000112388
ENSDART00000135176
ribonuclease like 4
chr9_-_9419704 0.26 ENSDART00000138996
si:ch211-214p13.9
chr3_-_26921475 0.26 ENSDART00000130281
class II, major histocompatibility complex, transactivator
chr6_-_35046735 0.25 ENSDART00000143649
UDP-N-acetylglucosamine pyrophosphorylase 1
chr12_-_29305533 0.25 ENSDART00000189410
SH2 domain containing 4Bb
chr15_-_16884912 0.25 ENSDART00000062135
zgc:103681
chr12_-_29305220 0.25 ENSDART00000153458
SH2 domain containing 4Bb
chr25_-_35095129 0.25 ENSDART00000099866
ENSDART00000099868
kinesin family member 15
chr22_+_9806867 0.24 ENSDART00000137182
ENSDART00000106103
si:ch211-236g6.1
chr2_-_58075414 0.24 ENSDART00000161920
nectin cell adhesion molecule 4
chr8_+_22478090 0.24 ENSDART00000170263
si:ch211-261n11.7
chr23_+_46183410 0.24 ENSDART00000167596
ENSDART00000151149
ENSDART00000150896
bloodthirsty-related gene family, member 31
chr18_-_16801033 0.24 ENSDART00000100100
adrenomedullin b
chr4_-_77135340 0.24 ENSDART00000180581
ENSDART00000179901

chr23_+_24272421 0.24 ENSDART00000029974
chloride channel K
chr19_-_703898 0.23 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr7_-_32021853 0.23 ENSDART00000134521
kinesin family member 18A
chr1_+_58182400 0.22 ENSDART00000144784
si:ch211-15j1.1
chr1_+_58260886 0.22 ENSDART00000110453
si:dkey-222h21.8
chr4_-_77120928 0.21 ENSDART00000174154

chr12_-_44072716 0.21 ENSDART00000162509
si:ch73-329n5.3
chr1_-_52497834 0.21 ENSDART00000136469
ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr23_+_3594171 0.21 ENSDART00000159609
si:dkey-9l20.3
chr3_+_56876280 0.21 ENSDART00000154197
amnion associated transmembrane protein
chr3_-_3448095 0.21 ENSDART00000078886
si:dkey-46g23.5
chr24_-_28419444 0.21 ENSDART00000105749
negative regulator of reactive oxygen species
chr20_+_6535438 0.21 ENSDART00000145763
si:ch211-191a24.4
chr23_-_27701361 0.21 ENSDART00000186688
ENSDART00000183985
DnaJ (Hsp40) homolog, subfamily C, member 22
chr22_-_31020690 0.21 ENSDART00000130604
ssu-2 homolog, tandem duplicate 4
chr2_-_17115256 0.21 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr16_-_24668620 0.21 ENSDART00000012807
paraoxonase 3, tandem duplicate 2
chr7_+_41887429 0.21 ENSDART00000115090
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr8_-_21091961 0.21 ENSDART00000100281
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2
chr8_-_38616712 0.20 ENSDART00000141827
si:ch211-198d23.1
chr15_-_23206562 0.20 ENSDART00000110360
coiled-coil domain containing 153
chr21_-_1640547 0.20 ENSDART00000151041
zgc:152948
chr24_-_2843107 0.20 ENSDART00000165290
cytochrome b5 type A (microsomal)
chr1_-_58868306 0.20 ENSDART00000166615
dynamin 2b
chr5_-_38197080 0.20 ENSDART00000140708
si:ch211-284e13.9
chr7_+_14005111 0.20 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr22_-_38274188 0.20 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr25_+_27923846 0.20 ENSDART00000047007
solute carrier family 13 member 1
chr22_+_19407531 0.20 ENSDART00000141060
si:dkey-78l4.2
chr15_+_28268135 0.20 ENSDART00000152536
ENSDART00000188550
myosin Ic, paralog b
chr23_+_24124684 0.19 ENSDART00000144478
si:dkey-21o19.2
chr18_-_48550426 0.19 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr20_-_26936887 0.19 ENSDART00000160827
finTRIM family, member 79
chr16_+_50289916 0.19 ENSDART00000168861
ENSDART00000167332
hepcidin antimicrobial peptide
chr17_+_15213496 0.19 ENSDART00000058351
ENSDART00000131663
glucosamine-phosphate N-acetyltransferase 1
chr19_+_2877079 0.19 ENSDART00000160847
HGH1 homolog (S. cerevisiae)
chr1_+_57050899 0.18 ENSDART00000152601
si:ch211-1f22.14
chr7_-_5039562 0.18 ENSDART00000154438
leukotriene B4 receptor
chr20_+_6535176 0.18 ENSDART00000054652
si:ch211-191a24.4
chr7_+_22586800 0.18 ENSDART00000035325
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr4_-_16451375 0.17 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
chr23_+_42454292 0.17 ENSDART00000171459
y cytochrome P450, family 2, subfamily AA, polypeptide 2
chr1_-_59139599 0.17 ENSDART00000152233
si:ch1073-110a20.3
chr16_-_19568795 0.17 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr10_-_690072 0.17 ENSDART00000164871
ENSDART00000142833
GLIS family zinc finger 3
chr8_-_52909850 0.17 ENSDART00000161943
nuclear receptor subfamily 6, group A, member 1a
chr1_+_38153944 0.17 ENSDART00000135666
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr12_-_145076 0.17 ENSDART00000160926
dynein, axonemal, heavy chain 9
chr6_+_7414215 0.17 ENSDART00000049339
SRY (sex determining region Y)-box 21a
chr6_-_35439406 0.16 ENSDART00000073784
regulator of G protein signaling 5a
chr18_-_43866526 0.16 ENSDART00000111309
trehalase (brush-border membrane glycoprotein)
chr23_-_16737161 0.16 ENSDART00000132573
si:ch211-224l10.4
chr20_+_49119633 0.16 ENSDART00000151435
CD109 molecule
chr3_-_34561624 0.16 ENSDART00000129313
septin 9a
chr13_-_214122 0.16 ENSDART00000169273
protein phosphatase 1, regulatory subunit 21
chr5_+_36896933 0.16 ENSDART00000151984
serine/arginine-rich splicing factor 7a
chr16_-_11859309 0.16 ENSDART00000145754
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr1_-_9644630 0.16 ENSDART00000123725
ENSDART00000161164
UDP glucuronosyltransferase 5 family, polypeptide B3
chr21_+_6034783 0.16 ENSDART00000169613
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr19_+_2631565 0.16 ENSDART00000171487
family with sequence similarity 126, member A
chr24_+_13869092 0.16 ENSDART00000176492
EYA transcriptional coactivator and phosphatase 1
chr8_+_22477922 0.16 ENSDART00000189766
ENSDART00000179717
si:ch211-261n11.7
chr5_-_36549024 0.16 ENSDART00000097671
zgc:158432
chr18_-_46295132 0.16 ENSDART00000190940
phospholipase D family, member 3
chr4_-_10972912 0.16 ENSDART00000102496
si:ch211-161n3.3
chr22_-_28668442 0.15 ENSDART00000182377
collagen, type VIII, alpha 1b
chr1_-_57129179 0.15 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
chr5_-_3839285 0.15 ENSDART00000122292
MLX interacting protein like
chr15_+_5973909 0.15 ENSDART00000126886
ENSDART00000189618
immunoglobulin superfamily, member 5b
chr24_-_25186895 0.15 ENSDART00000081029
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_+_30501135 0.15 ENSDART00000165869
si:dkey-13n23.3
chr20_+_18260358 0.15 ENSDART00000187734
ENSDART00000191947
ENSDART00000057039
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_+_33172066 0.15 ENSDART00000174013
si:ch211-194p6.12
chr3_+_23047241 0.15 ENSDART00000103858
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr2_-_3045861 0.14 ENSDART00000105818
ENSDART00000187575
guanylate kinase 1a
chr25_+_418932 0.14 ENSDART00000059193
protogenin homolog b (Gallus gallus)
chr1_+_56886214 0.14 ENSDART00000152718
ENSDART00000182408
si:ch211-1f22.8
chr3_+_30257582 0.14 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
myosin binding protein C, fast type a
chr17_-_27200025 0.14 ENSDART00000192699
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr18_-_48492951 0.14 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr20_+_49081967 0.14 ENSDART00000112689
crooked neck pre-mRNA splicing factor 1
chr22_-_7050 0.14 ENSDART00000127829
ATPase family, AAA domain containing 3
chr4_-_17741513 0.14 ENSDART00000141680
myosin binding protein C, slow type
chr10_+_45031398 0.14 ENSDART00000160536
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr25_+_7591293 0.14 ENSDART00000130416

chr21_-_40083432 0.13 ENSDART00000141160
ENSDART00000191195
info solute carrier family 13 (sodium-dependent citrate transporter), member 5a
chr10_+_26646104 0.13 ENSDART00000187685
adhesion G protein-coupled receptor G4b
chr17_-_12196865 0.13 ENSDART00000154694
kinesin family member 28
chr7_-_51775688 0.13 ENSDART00000149793
bone morphogenetic protein 15
chr5_-_8907819 0.13 ENSDART00000188523
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr5_+_37406358 0.13 ENSDART00000162811
kelch-like family member 13
chr12_+_47439 0.13 ENSDART00000114732
mitochondrial ribosomal protein L58
chr20_-_36887516 0.13 ENSDART00000076313
taxilin beta a
chr14_+_31788733 0.12 ENSDART00000109063
CD40 ligand
chr12_+_45238292 0.12 ENSDART00000057983
mitochondrial ribosomal protein L38
chr22_-_4913031 0.12 ENSDART00000132062
si:ch73-256j6.3
chr10_+_26645953 0.12 ENSDART00000131482
adhesion G protein-coupled receptor G4b
chr7_+_29012033 0.12 ENSDART00000173909
ENSDART00000145762
dynein, axonemal, assembly factor 1
chr22_-_6923347 0.12 ENSDART00000082048

chr16_-_30927454 0.12 ENSDART00000184015
solute carrier family 45, member 4
chr13_-_11578304 0.12 ENSDART00000171145
si:ch211-132e22.4
chr7_-_59256806 0.12 ENSDART00000167955
meiosis 1 associated protein
chr23_+_5736226 0.12 ENSDART00000134527
ENSDART00000112220
finTRIM family, member 57
chr14_+_30413312 0.12 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr20_-_36887176 0.12 ENSDART00000143515
ENSDART00000146994
taxilin beta a
chr19_+_19652439 0.12 ENSDART00000165934
3-hydroxyisobutyrate dehydrogenase a
chr14_-_17121676 0.12 ENSDART00000170154
ENSDART00000060479
smoothelin-like 1
chr19_-_17972734 0.12 ENSDART00000126298
integrator complex subunit 8
chr11_-_12530304 0.11 ENSDART00000143061
zgc:174354
chr9_-_42861080 0.11 ENSDART00000193688
titin, tandem duplicate 1
chr4_+_70013627 0.11 ENSDART00000180432
si:dkey-190j3.4
chr16_+_52343905 0.11 ENSDART00000131051
interferon lambda receptor 1
chr2_+_5793908 0.11 ENSDART00000145219
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1b
chr17_-_25303486 0.11 ENSDART00000162235
peptidylprolyl isomerase E (cyclophilin E)
chr5_-_39698224 0.11 ENSDART00000076929
protein kinase, cGMP-dependent, type II
chr1_+_24557414 0.11 ENSDART00000076519
dCTP pyrophosphatase 1
chr12_-_3940768 0.10 ENSDART00000134292
zgc:92040
chr6_-_16948040 0.10 ENSDART00000156433
Pim proto-oncogene, serine/threonine kinase, related 30
chr7_-_71331690 0.10 ENSDART00000149682
DEAH (Asp-Glu-Ala-His) box helicase 15
chr23_+_42396934 0.10 ENSDART00000169821
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr25_-_15245475 0.10 ENSDART00000142943
coiled-coil domain containing 73
chr10_+_10351685 0.10 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr18_+_44769027 0.10 ENSDART00000145190
ilvB (bacterial acetolactate synthase)-like
chr6_-_16868834 0.10 ENSDART00000156503
Pim proto-oncogene, serine/threonine kinase, related 41
chr5_+_52167986 0.10 ENSDART00000162256
ENSDART00000073626
solute carrier family 14 (urea transporter), member 2
chr3_-_34052882 0.10 ENSDART00000151463
immunoglobulin heavy variable 11-1

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.4 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.4 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.4 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.2 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.1 0.2 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.2 GO:0005991 trehalose metabolic process(GO:0005991)
0.0 0.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.6 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.5 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.1 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.3 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.3 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.2 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.1 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.5 GO:0032355 response to estradiol(GO:0032355)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005948 acetolactate synthase complex(GO:0005948)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.5 GO:0045735 nutrient reservoir activity(GO:0045735)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.1 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.2 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.2 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 0.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0003984 acetolactate synthase activity(GO:0003984)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.0 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis