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PRJNA207719: Tissue specific transcriptome profiling

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Results for nr6a1a

Z-value: 2.37

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Transcription factors associated with nr6a1a

Gene Symbol Gene ID Gene Info
nr6a1a
ENSDARG00000101508 nuclear receptor subfamily 6, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr6a1adr11_v1_chr8_-_52938439_52938439-0.731.6e-01Click!

Activity profile of nr6a1a motif

Sorted Z-values of nr6a1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_12660318 3.98 ENSDART00000008498
adh8a
alcohol dehydrogenase 8a
chr20_+_10539293 3.03 ENSDART00000182265
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr4_-_17409533 2.13 ENSDART00000011943
pah
phenylalanine hydroxylase
chr22_-_24858042 2.08 ENSDART00000137998
ENSDART00000078216
ENSDART00000138378
vtg7
vitellogenin 7
chr3_+_19299309 2.01 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr20_+_10545514 2.01 ENSDART00000153667
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_+_1769475 1.82 ENSDART00000079073
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr15_-_26549693 1.67 ENSDART00000186432
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr6_-_8498908 1.52 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr6_-_8498676 1.46 ENSDART00000148627
pglyrp2
peptidoglycan recognition protein 2
chr9_-_48700806 1.42 ENSDART00000026210
rdh1
retinol dehydrogenase 1
chr20_-_30370884 1.40 ENSDART00000062429
allc
allantoicase
chr2_-_50225411 1.32 ENSDART00000147117
ENSDART00000000042
mcm6l
MCM6 minichromosome maintenance deficient 6, like
chr3_-_3448095 1.28 ENSDART00000078886
A2ML1 (1 of many)
si:dkey-46g23.5
chr15_+_14854666 1.27 ENSDART00000163066
diabloa
diablo, IAP-binding mitochondrial protein a
chr16_-_45235947 1.27 ENSDART00000164436
si:dkey-33i11.4
si:dkey-33i11.4
chr5_-_37103487 1.26 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr21_-_30658509 1.24 ENSDART00000139764
si:dkey-22f5.9
si:dkey-22f5.9
chr7_+_19482084 1.19 ENSDART00000173873
si:ch211-212k18.7
si:ch211-212k18.7
chr16_+_49249669 1.19 ENSDART00000181899
LO018128.1

chr21_-_43636595 1.17 ENSDART00000151115
ENSDART00000151486
ENSDART00000151778
si:ch1073-263o8.2
si:ch1073-263o8.2
chr25_-_29415369 1.16 ENSDART00000110774
ENSDART00000019183
ugt5a2
ugt5a1
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr2_+_51028269 1.14 ENSDART00000161254
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr8_+_19514294 1.13 ENSDART00000170622
si:ch73-281k2.5
si:ch73-281k2.5
chr3_+_21189766 1.12 ENSDART00000078807
zgc:123295
zgc:123295
chr19_-_14155781 1.07 ENSDART00000169232
nr0b2b
nuclear receptor subfamily 0, group B, member 2b
chr24_-_9989634 1.06 ENSDART00000115275
zgc:152652
zgc:152652
chr9_-_48701035 1.06 ENSDART00000178332
rdh1
retinol dehydrogenase 1
chr25_+_34576067 1.01 ENSDART00000157519
trpm1b
transient receptor potential cation channel, subfamily M, member 1b
chr25_+_3327071 1.01 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr10_-_22497980 1.01 ENSDART00000185549
CT573337.2

chr24_-_9979342 1.01 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr12_-_4346085 1.00 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr7_-_60831082 0.99 ENSDART00000073654
ENSDART00000136999
pcxb
pyruvate carboxylase b
chr18_+_8340886 0.98 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr25_+_22107643 0.98 ENSDART00000089680
sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr3_+_39540014 0.98 ENSDART00000074848
zgc:165423
zgc:165423
chr22_+_25086942 0.98 ENSDART00000061117
rrbp1b
ribosome binding protein 1b
chr25_+_10830269 0.98 ENSDART00000175736
si:ch211-147g22.5
si:ch211-147g22.5
chr2_-_37210397 0.97 ENSDART00000084938
apoda.1
apolipoprotein Da, duplicate 1
chr22_+_25086567 0.97 ENSDART00000192114
ENSDART00000177284
ENSDART00000180296
ENSDART00000190384
rrbp1b
ribosome binding protein 1b
chr15_+_28410664 0.94 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr19_+_32855139 0.92 ENSDART00000052082
rpl30
ribosomal protein L30
chr5_-_41531629 0.91 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr19_-_42571829 0.90 ENSDART00000102606
zgc:103438
zgc:103438
chr25_+_3326885 0.89 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr8_-_14091886 0.86 ENSDART00000137857
si:ch211-229n2.7
si:ch211-229n2.7
chr22_-_23781083 0.86 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
cfhl3
complement factor H like 3
chr16_+_29509133 0.83 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr1_-_7998493 0.83 ENSDART00000185901
si:dkey-79f11.5
si:dkey-79f11.5
chr23_-_10175898 0.83 ENSDART00000146185
krt5
keratin 5
chr13_+_8306399 0.81 ENSDART00000080339
galm
galactose mutarotase
chr20_+_25581627 0.81 ENSDART00000030229
cyp2p9
cytochrome P450, family 2, subfamily P, polypeptide 9
chr11_+_14333441 0.80 ENSDART00000171969
ptbp1b
polypyrimidine tract binding protein 1b
chr4_+_77948517 0.79 ENSDART00000149305
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr2_-_23569833 0.78 ENSDART00000138889
si:dkey-58b18.10
si:dkey-58b18.10
chr12_+_45676667 0.77 ENSDART00000016553
si:ch73-111m19.2
si:ch73-111m19.2
chr9_+_42270043 0.76 ENSDART00000137435
si:dkey-10c21.1
si:dkey-10c21.1
chr10_+_37927100 0.76 ENSDART00000172548
bhlha9
basic helix-loop-helix family, member a9
chr9_+_13682133 0.76 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr8_-_8489886 0.74 ENSDART00000183334
abt1
activator of basal transcription 1
chr22_-_17781213 0.74 ENSDART00000137984
si:ch73-63e15.2
si:ch73-63e15.2
chr3_+_32112004 0.72 ENSDART00000105272
zgc:173593
zgc:173593
chr21_+_20901505 0.71 ENSDART00000132741
c7b
complement component 7b
chr7_+_52122224 0.71 ENSDART00000174268
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr3_-_36823643 0.70 ENSDART00000131340
ENSDART00000185075
abcc6b.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2
chr15_+_26600611 0.70 ENSDART00000155352
slc47a3
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr2_+_30032303 0.70 ENSDART00000151841
rbm33b
RNA binding motif protein 33b
chr3_-_1970820 0.69 ENSDART00000136467
si:ch211-254c8.3
si:ch211-254c8.3
chr22_-_17462895 0.68 ENSDART00000160415
si:ch211-197g15.6
si:ch211-197g15.6
chr5_-_41834999 0.68 ENSDART00000135772
si:dkey-65b12.6
si:dkey-65b12.6
chr7_-_37917517 0.67 ENSDART00000173795
heatr3
HEAT repeat containing 3
chr5_-_50992690 0.67 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr3_+_2669813 0.67 ENSDART00000014205
CR388047.1

chr3_-_10677890 0.67 ENSDART00000155382
ENSDART00000171319
si:ch1073-144j5.2
si:ch1073-144j5.2
chr9_-_14055959 0.67 ENSDART00000146675
fer1l6
fer-1-like family member 6
chr22_+_21152847 0.66 ENSDART00000007321
crlf1b
cytokine receptor-like factor 1b
chr2_-_23538794 0.66 ENSDART00000143857
si:dkey-58b18.10
si:dkey-58b18.10
chr3_+_24612191 0.65 ENSDART00000190998
zgc:171506
zgc:171506
chr10_+_33393829 0.65 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr24_+_19986432 0.65 ENSDART00000184402
CR381686.5

chr25_+_18587338 0.65 ENSDART00000180287
met
MET proto-oncogene, receptor tyrosine kinase
chr8_-_2153147 0.64 ENSDART00000124093
si:dkeyp-117b11.1
si:dkeyp-117b11.1
chr22_-_22337382 0.64 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr10_-_36793412 0.64 ENSDART00000185966
dhrs13a.2
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 2
chr25_-_13188678 0.64 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr21_-_17956739 0.63 ENSDART00000148154
stx2a
syntaxin 2a
chr1_-_11104805 0.63 ENSDART00000147648
knl1
kinetochore scaffold 1
chr9_-_1970071 0.63 ENSDART00000080608
hoxd10a
homeobox D10a
chr2_-_20120904 0.62 ENSDART00000186002
ENSDART00000124724
dpydb
dihydropyrimidine dehydrogenase b
chr2_-_23600821 0.62 ENSDART00000146217
BX677666.1

chr3_-_7656059 0.62 ENSDART00000170917
junbb
JunB proto-oncogene, AP-1 transcription factor subunit b
chr9_-_12888082 0.61 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr21_-_5879897 0.61 ENSDART00000184034
rpl35
ribosomal protein L35
chr19_+_7878122 0.61 ENSDART00000131917
si:dkeyp-85e10.2
si:dkeyp-85e10.2
chr10_+_40629616 0.61 ENSDART00000147476
CR396590.9

chr5_-_11971946 0.61 ENSDART00000166285
si:ch73-47f2.1
si:ch73-47f2.1
chr8_-_45759137 0.61 ENSDART00000123878
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr7_-_58826164 0.60 ENSDART00000171095
sox32
SRY (sex determining region Y)-box 32
chr22_+_21153031 0.60 ENSDART00000166342
crlf1b
cytokine receptor-like factor 1b
chr3_+_13469704 0.60 ENSDART00000166806
zgc:77748
zgc:77748
chr21_-_22869802 0.58 ENSDART00000189917
polq
polymerase (DNA directed), theta
chr5_+_9259971 0.58 ENSDART00000163060
susd1
sushi domain containing 1
chr19_+_4038589 0.57 ENSDART00000169271
btr23
bloodthirsty-related gene family, member 23
chr21_+_43702016 0.57 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr19_-_5135345 0.56 ENSDART00000151787
gnb3b
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr25_-_13202208 0.56 ENSDART00000168155
si:ch211-194m7.4
si:ch211-194m7.4
chr17_+_450956 0.56 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr3_-_36824190 0.56 ENSDART00000172943
abcc6b.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2
chr5_+_22579975 0.55 ENSDART00000080877
tnfsf10l4
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr10_+_44719697 0.55 ENSDART00000158087
scarb1
scavenger receptor class B, member 1
chr25_-_35143360 0.55 ENSDART00000188033
zgc:165555
zgc:165555
chr25_+_14092871 0.54 ENSDART00000067239
guca1g
guanylate cyclase activator 1g
chr16_-_12319822 0.53 ENSDART00000127453
ENSDART00000184526
trpv6
transient receptor potential cation channel, subfamily V, member 6
chr16_-_34195002 0.53 ENSDART00000054026
rcc1
regulator of chromosome condensation 1
chr3_+_30921246 0.53 ENSDART00000076850
cldni
claudin i
chr5_+_50879545 0.53 ENSDART00000128402
nol6
nucleolar protein 6 (RNA-associated)
chr21_-_17956416 0.52 ENSDART00000026737
stx2a
syntaxin 2a
chr2_-_44344321 0.52 ENSDART00000084174
lig1
ligase I, DNA, ATP-dependent
chr18_+_36631923 0.52 ENSDART00000098980
znf296
zinc finger protein 296
chr8_+_44703864 0.51 ENSDART00000016225
star
steroidogenic acute regulatory protein
chr16_+_21790870 0.51 ENSDART00000155039
trim108
tripartite motif containing 108
chr8_-_20245892 0.51 ENSDART00000136911
acer1
alkaline ceramidase 1
chr18_-_26854959 0.51 ENSDART00000057553
ch25hl1.1
cholesterol 25-hydroxylase like 1, tandem duplicate 1
chr10_-_11383900 0.50 ENSDART00000101045
plac8.1
placenta-specific 8, tandem duplicate 1
chr7_+_21272833 0.50 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr14_+_34514336 0.50 ENSDART00000024440
foxi3b
forkhead box I3b
chr14_+_16034447 0.50 ENSDART00000161348
prelid1a
PRELI domain containing 1a
chr10_+_7719796 0.50 ENSDART00000191795
ggcx
gamma-glutamyl carboxylase
chr5_-_26936861 0.49 ENSDART00000191032
htra4
HtrA serine peptidase 4
chr5_+_9434288 0.49 ENSDART00000162089
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr23_+_36087219 0.49 ENSDART00000154825
hoxc3a
homeobox C3a
chr25_-_34512102 0.49 ENSDART00000087450
klf13
Kruppel-like factor 13
chr16_+_23960933 0.48 ENSDART00000146077
apoeb
apolipoprotein Eb
chr3_+_31662126 0.48 ENSDART00000113441
mylk5
myosin, light chain kinase 5
chr3_-_32957702 0.48 ENSDART00000146586
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr8_+_42717005 0.48 ENSDART00000181656
ENSDART00000180320
ENSDART00000181293
zgc:194007
zgc:194007
chr5_-_41841675 0.48 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr1_+_24557414 0.48 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr3_+_1749793 0.48 ENSDART00000149308
si:dkeyp-52c3.7
si:dkeyp-52c3.7
chr12_-_17024079 0.48 ENSDART00000129027
ifit11
interferon-induced protein with tetratricopeptide repeats 11
chr13_-_14926318 0.47 ENSDART00000142785
cdc25b
cell division cycle 25B
chr14_+_6535426 0.47 ENSDART00000055961
thg1l
tRNA-histidine guanylyltransferase 1-like
chr4_+_29620959 0.47 ENSDART00000133110
si:ch211-214c20.1
si:ch211-214c20.1
chr15_-_41720173 0.47 ENSDART00000155585
ENSDART00000075909
ftr76
finTRIM family, member 76
chr8_+_44478294 0.46 ENSDART00000006898
si:ch73-211l2.3
si:ch73-211l2.3
chr5_+_1983495 0.46 ENSDART00000179860
CT573103.2

chr24_+_34069675 0.46 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr3_+_4346854 0.46 ENSDART00000004273
si:dkey-73p2.3
si:dkey-73p2.3
chr12_+_30788912 0.45 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr2_-_42492201 0.45 ENSDART00000180762
ENSDART00000009093
esyt2a
extended synaptotagmin-like protein 2a
chr24_-_25256230 0.45 ENSDART00000155780
hhla2b.1
HERV-H LTR-associating 2b, tandem duplicate 1
chr11_+_2198831 0.45 ENSDART00000160515
hoxc6b
homeobox C6b
chr23_-_43393083 0.45 ENSDART00000112758
zgc:174862
zgc:174862
chr19_-_703898 0.45 ENSDART00000181096
ENSDART00000121462
slc6a19a.2
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr7_-_24181159 0.43 ENSDART00000181206
zgc:153151
zgc:153151
chr7_-_15370042 0.43 ENSDART00000128183
ANPEP
si:ch211-276a23.5
chr5_-_9090178 0.43 ENSDART00000091472
kcnv2b
potassium channel, subfamily V, member 2b
chr22_+_9126557 0.43 ENSDART00000190669
si:ch211-156p11.1
si:ch211-156p11.1
chr6_+_42338309 0.43 ENSDART00000015277
gpx1b
glutathione peroxidase 1b
chr3_+_23697997 0.43 ENSDART00000184299
ENSDART00000078466
hoxb3a
homeobox B3a
chr9_-_44939104 0.42 ENSDART00000192903
vil1
villin 1
chr4_+_58668661 0.42 ENSDART00000188815
CR388148.2

chr4_-_34775762 0.42 ENSDART00000167262
si:dkey-146m20.14
si:dkey-146m20.14
chr17_-_6765877 0.42 ENSDART00000193102
CR352340.1

chr5_-_9948497 0.41 ENSDART00000183196
tor4ab
torsin family 4, member Ab
chr16_+_23961276 0.41 ENSDART00000192754
apoeb
apolipoprotein Eb
chr22_-_6229275 0.41 ENSDART00000146045
ENSDART00000179730
si:ch211-274k16.2
si:ch211-274k16.2
chr3_+_12484008 0.41 ENSDART00000182229
vasnb
vasorin b
chr18_+_8912113 0.41 ENSDART00000147467
tmem243a
transmembrane protein 243, mitochondrial a
chr5_+_8246603 0.41 ENSDART00000167373
si:ch1073-475a24.1
si:ch1073-475a24.1
chr9_+_29548195 0.40 ENSDART00000176057
rnf17
ring finger protein 17
chr25_+_23280220 0.40 ENSDART00000153940
ptprjb.1
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr2_+_52232630 0.40 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr14_+_32838110 0.40 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr21_-_33126697 0.40 ENSDART00000189293
ENSDART00000084559
CU019662.1

chr1_+_56886214 0.40 ENSDART00000152718
ENSDART00000182408
si:ch211-1f22.8
si:ch211-1f22.8
chr4_-_39479644 0.39 ENSDART00000183332
si:dkey-261o4.6
si:dkey-261o4.6
chr17_+_6538733 0.39 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr1_-_8566567 0.39 ENSDART00000114613
ptcd1
pentatricopeptide repeat domain 1
chr9_+_24088062 0.38 ENSDART00000126198
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr20_-_43771871 0.38 ENSDART00000153304
matn3a
matrilin 3a
chr4_-_75795899 0.38 ENSDART00000157925
si:dkey-261j11.1
si:dkey-261j11.1
chr4_+_76973771 0.38 ENSDART00000142978
si:dkey-240n22.3
si:dkey-240n22.3
chr8_+_22472584 0.38 ENSDART00000138303
si:dkey-23c22.9
si:dkey-23c22.9
chr17_-_8862424 0.37 ENSDART00000064633
nkl.4
NK-lysin tandem duplicate 4
chr3_-_39627412 0.37 ENSDART00000123292
si:dkey-27o4.1
si:dkey-27o4.1
chr3_-_49015203 0.37 ENSDART00000186138
BX769173.2

chr14_+_32837914 0.37 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr25_-_16742438 0.37 ENSDART00000156091
galnt8a.1
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 1
chr17_+_38566717 0.37 ENSDART00000145147
sptb
spectrin, beta, erythrocytic
chr4_+_60547709 0.37 ENSDART00000158732
si:dkey-211i20.5
si:dkey-211i20.5
chr25_-_12804450 0.37 ENSDART00000169717
ca5a
carbonic anhydrase Va
chr20_+_35445462 0.36 ENSDART00000124497
tdrd6
tudor domain containing 6
chr7_-_16034324 0.36 ENSDART00000002498
ENSDART00000162962
elp4
elongator acetyltransferase complex subunit 4
chr25_+_17860962 0.36 ENSDART00000163153
pth1a
parathyroid hormone 1a
chr16_-_17197546 0.36 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr2_+_7818368 0.36 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr4_-_38829098 0.36 ENSDART00000151932
si:dkey-59l11.10
si:dkey-59l11.10
chr15_-_28082310 0.36 ENSDART00000152620
dhrs13a.3
dehydrogenase/reductase (SDR family) member 13a, duplicate 3

Network of associatons between targets according to the STRING database.

First level regulatory network of nr6a1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.6 4.0 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.5 1.4 GO:0000256 allantoin catabolic process(GO:0000256)
0.4 2.5 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.4 1.2 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 1.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.3 0.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.7 GO:0000480 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.6 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 3.8 GO:0042574 retinal metabolic process(GO:0042574)
0.2 0.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 0.5 GO:0035376 sterol import(GO:0035376) recognition of apoptotic cell(GO:0043654) cholesterol import(GO:0070508)
0.2 2.1 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 0.9 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.2 0.8 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.5 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.2 0.8 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 0.5 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.6 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 1.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.4 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 9.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.4 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.5 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.3 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 0.8 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.6 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1 0.7 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.4 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.4 GO:0016037 light absorption(GO:0016037)
0.1 0.2 GO:0033212 iron assimilation(GO:0033212)
0.1 0.3 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.8 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 0.6 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 1.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.6 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 2.1 GO:0032355 response to estradiol(GO:0032355)
0.1 1.0 GO:0046686 response to cadmium ion(GO:0046686)
0.1 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 1.3 GO:0000302 response to reactive oxygen species(GO:0000302)
0.0 1.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 1.0 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.6 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 1.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.7 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0046661 male sex differentiation(GO:0046661)
0.0 1.0 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 1.1 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.0 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0048844 artery morphogenesis(GO:0048844)
0.0 2.2 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.3 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 1.4 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0050821 protein stabilization(GO:0050821)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.0 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 1.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.5 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.2 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.4 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0032433 filopodium tip(GO:0032433)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 1.3 GO:0042555 MCM complex(GO:0042555)
0.1 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.3 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 14.9 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.8 4.0 GO:0051903 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.5 2.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.4 3.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 1.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 1.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 2.1 GO:0045735 nutrient reservoir activity(GO:0045735)
0.3 0.9 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 1.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.3 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 2.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 0.5 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 1.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.5 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 1.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.7 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 9.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.5 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.4 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.5 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.5 GO:0010853 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.7 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0004096 catalase activity(GO:0004096)
0.0 0.2 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 1.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 1.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.0 GO:0019955 cytokine binding(GO:0019955)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0050661 NADP binding(GO:0050661)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.7 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 1.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)