ISMARA results: olig3_olig2+olig4

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PRJNA207719: Tissue specific transcriptome profiling

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Results for olig3_olig2+olig4_olig1

Z-value: 0.67

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Transcription factors associated with olig3_olig2+olig4_olig1

Gene Symbol	Gene ID	Gene Info
olig3 NCBI UniProt	ENSDARG00000074253	oligodendrocyte transcription factor 3
olig2 NCBI UniProt	ENSDARG00000040946	oligodendrocyte lineage transcription factor 2
olig4 NCBI UniProt	ENSDARG00000052610	oligodendrocyte transcription factor 4
olig4 NCBI UniProt	ENSDARG00000116678	oligodendrocyte transcription factor 4
olig1 NCBI UniProt	ENSDARG00000040948	oligodendrocyte transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
olig4	dr11_v1_chr13_+_45967179_45967179	0.49	4.1e-01	Click!
olig1	dr11_v1_chr9_-_32730487_32730487	0.45	4.4e-01	Click!
olig2	dr11_v1_chr9_-_32753535_32753535	0.36	5.5e-01	Click!

Activity profile of olig3_olig2+olig4_olig1 motif

Sorted Z-values of olig3_olig2+olig4_olig1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_1518360 Show fit	0.41	ENSDART00000182788	c8b NCBI UniProt Show fit	complement component 8, beta polypeptide
chr22_-_24818066 Show fit	0.33	ENSDART00000143443	vtg6 NCBI UniProt Show fit	vitellogenin 6
chr21_+_6751405 Show fit	0.30	ENSDART00000037265 ENSDART00000146371	olfm1b NCBI UniProt Show fit	olfactomedin 1b
chr8_-_39952727 Show fit	0.27	ENSDART00000181310	cabp1a NCBI UniProt Show fit	calcium binding protein 1a
chr15_+_36457888 Show fit	0.26	ENSDART00000155100	si:dkey-262k9.2 NCBI UniProt Show fit	si:dkey-262k9.2
chr18_+_13164325 Show fit	0.26	ENSDART00000189057	tat NCBI UniProt Show fit	tyrosine aminotransferase
chr14_-_25599002 Show fit	0.26	ENSDART00000040955	slc25a48 NCBI UniProt Show fit	solute carrier family 25, member 48
chr16_+_50289916 Show fit	0.25	ENSDART00000168861 ENSDART00000167332	hamp NCBI UniProt Show fit	hepcidin antimicrobial peptide
chr22_-_18116635 Show fit	0.25	ENSDART00000005724	ncanb NCBI UniProt Show fit	neurocan b
chr2_-_17947389 Show fit	0.24	ENSDART00000190089 ENSDART00000191872 ENSDART00000184039 ENSDART00000179791	ptprfb NCBI UniProt Show fit	protein tyrosine phosphatase, receptor type, f, b

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of olig3_olig2+olig4_olig1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	GO:0032355	response to estradiol(GO:0032355)
0.0	0.4	GO:0019835	cytolysis(GO:0019835)
0.1	0.3	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.3	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.3	GO:0032570	response to progesterone(GO:0032570)
0.0	0.3	GO:0006567	threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0	0.3	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.2	GO:0006844	acyl carnitine transport(GO:0006844)
0.0	0.2	GO:0019370	leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0	0.2	GO:0032656	interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)

Showing 1 to 10 of 61 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.3	GO:0034361	very-low-density lipoprotein particle(GO:0034361)
0.2	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	GO:0005579	membrane attack complex(GO:0005579)
0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	GO:0032545	CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1	GO:0005955	calcineurin complex(GO:0005955)
0.1	GO:0070695	FHF complex(GO:0070695)
0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)

Showing 1 to 10 of 20 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0045735	nutrient reservoir activity(GO:0045735)
0.1	0.3	GO:0008743	L-threonine 3-dehydrogenase activity(GO:0008743)
0.0	0.3	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.2	GO:0015227	acyl carnitine transmembrane transporter activity(GO:0015227)
0.0	0.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.2	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0036374	peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)

Showing 1 to 10 of 44 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway

Showing 1 to 1 of 1 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis

Showing 1 to 2 of 2 entries

Results for olig3_olig2+olig4_olig1

Z-value: 0.67

Motif logo

Transcription factors associated with olig3_olig2+olig4_olig1

Activity-expression correlation:

Activity profile of olig3_olig2+olig4_olig1 motif

Sorted Z-values of olig3_olig2+olig4_olig1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of olig3_olig2+olig4_olig1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: