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PRJNA207719: Tissue specific transcriptome profiling

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Results for onecut1+onecutl

Z-value: 2.85

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Transcription factors associated with onecut1+onecutl

Gene Symbol Gene ID Gene Info
onecut1
ENSDARG00000007982 one cut homeobox 1
onecutl
ENSDARG00000040253 one cut domain, family member, like
onecut1
ENSDARG00000112251 one cut homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
onecutldr11_v1_chr16_-_29528198_295281980.894.2e-02Click!
onecut1dr11_v1_chr18_+_38755023_387550240.771.3e-01Click!

Activity profile of onecut1+onecutl motif

Sorted Z-values of onecut1+onecutl motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_7885707 3.03 ENSDART00000029981
ppp3cb
protein phosphatase 3, catalytic subunit, beta isozyme
chr8_-_31919624 2.48 ENSDART00000085573
rgs7bpa
regulator of G protein signaling 7 binding protein a
chr8_-_19051906 2.47 ENSDART00000089024
sema6bb
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr25_+_4837915 2.16 ENSDART00000168016
gnb5a
guanine nucleotide binding protein (G protein), beta 5a
chr19_-_9829965 2.16 ENSDART00000136842
ENSDART00000142766
cacng8a
calcium channel, voltage-dependent, gamma subunit 8a
chr13_+_16521898 2.10 ENSDART00000122557
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr21_-_27881752 2.09 ENSDART00000132583
nrxn2a
neurexin 2a
chr2_+_35240485 2.02 ENSDART00000179804
tnr
tenascin R (restrictin, janusin)
chr15_-_19677511 2.02 ENSDART00000043743
si:dkey-4p15.3
si:dkey-4p15.3
chr10_+_1638876 2.00 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
sgsm1b
small G protein signaling modulator 1b
chr3_-_12890670 1.95 ENSDART00000159934
ENSDART00000188607
btbd17b
BTB (POZ) domain containing 17b
chr2_+_35240764 1.95 ENSDART00000015827
tnr
tenascin R (restrictin, janusin)
chr21_-_41305748 1.93 ENSDART00000170457
nsg2
neuronal vesicle trafficking associated 2
chr10_+_7182168 1.93 ENSDART00000172766
psd3l
pleckstrin and Sec7 domain containing 3, like
chr21_+_9628854 1.92 ENSDART00000161753
ENSDART00000160711
mapk10
mitogen-activated protein kinase 10
chr12_+_24344611 1.89 ENSDART00000093094
nrxn1a
neurexin 1a
chr8_+_7740004 1.89 ENSDART00000170184
ENSDART00000187811
fgd1
FYVE, RhoGEF and PH domain containing 1
chr16_-_44649053 1.88 ENSDART00000184807
CR925804.2

chr7_+_23580082 1.78 ENSDART00000183245
si:dkey-172j4.3
si:dkey-172j4.3
chr20_+_3108597 1.75 ENSDART00000133435
CEP170B (1 of many)
si:ch73-212j7.1
chr10_+_25222367 1.71 ENSDART00000042767
grm5a
glutamate receptor, metabotropic 5a
chr15_-_25392589 1.71 ENSDART00000124205
si:dkey-54n8.4
si:dkey-54n8.4
chr23_+_28648864 1.70 ENSDART00000189096
l1cama
L1 cell adhesion molecule, paralog a
chr9_-_18424844 1.68 ENSDART00000154351
enox1
ecto-NOX disulfide-thiol exchanger 1
chr24_-_17444067 1.62 ENSDART00000155843
cntnap2a
contactin associated protein like 2a
chr6_+_55174744 1.60 ENSDART00000023562
SYT2
synaptotagmin 2
chr25_-_11088839 1.60 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr17_-_20979077 1.59 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr5_+_55626693 1.58 ENSDART00000168908
ENSDART00000161412
ntrk2b
neurotrophic tyrosine kinase, receptor, type 2b
chr13_+_16522608 1.58 ENSDART00000182838
ENSDART00000143200
kcnma1a
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr3_-_18711288 1.58 ENSDART00000183885
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr1_-_21409877 1.58 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr9_-_35557397 1.56 ENSDART00000100681
ncam2
neural cell adhesion molecule 2
chr15_+_26399538 1.55 ENSDART00000159589
rtn4rl1b
reticulon 4 receptor-like 1b
chr12_+_24344963 1.54 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
nrxn1a
neurexin 1a
chr7_-_22132265 1.52 ENSDART00000125284
ENSDART00000112978
nlgn2a
neuroligin 2a
chr6_+_3828560 1.52 ENSDART00000185273
ENSDART00000179091
gad1b
glutamate decarboxylase 1b
chr10_+_37137464 1.52 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr11_+_25111846 1.50 ENSDART00000128705
ENSDART00000190058
ndrg3a
ndrg family member 3a
chr15_-_24869826 1.50 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr4_+_10365857 1.49 ENSDART00000138890
kcnd2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr9_+_22631672 1.48 ENSDART00000101770
ENSDART00000126015
ENSDART00000145005
etv5a
ets variant 5a
chr24_+_24461558 1.42 ENSDART00000182424
bhlhe22
basic helix-loop-helix family, member e22
chr12_-_3756405 1.42 ENSDART00000150839
fam57bb
family with sequence similarity 57, member Bb
chr12_-_4781801 1.40 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr19_-_867071 1.40 ENSDART00000122257
eomesa
eomesodermin homolog a
chr14_+_22172047 1.40 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr19_+_25649626 1.39 ENSDART00000146947
tac1
tachykinin 1
chr3_-_28665291 1.39 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr1_+_12767318 1.39 ENSDART00000162652
pcdh10a
protocadherin 10a
chr19_-_9882821 1.38 ENSDART00000147128
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr25_+_19954576 1.38 ENSDART00000149335
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr16_+_5184402 1.36 ENSDART00000156685
soga3a
SOGA family member 3a
chr2_+_38608290 1.35 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr15_-_18429550 1.35 ENSDART00000136208
ncam1b
neural cell adhesion molecule 1b
chr5_-_23429228 1.32 ENSDART00000049291
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr6_-_38419318 1.32 ENSDART00000138026
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr7_+_30875273 1.31 ENSDART00000173693
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr3_-_23407720 1.31 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr12_-_13886952 1.30 ENSDART00000110503
adam11
ADAM metallopeptidase domain 11
chr8_+_23916647 1.28 ENSDART00000143152
cpne5a
copine Va
chr17_-_16133249 1.28 ENSDART00000030919
pnoca
prepronociceptin a
chr7_+_73649686 1.27 ENSDART00000185589
PCP4L1
si:dkey-46i9.1
chr16_+_21738194 1.24 ENSDART00000163688
FP085428.1
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr19_+_37701450 1.22 ENSDART00000087694
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr17_+_8183393 1.17 ENSDART00000155957
tulp4b
tubby like protein 4b
chr13_+_35746440 1.15 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr12_+_39685485 1.13 ENSDART00000163403
LO017650.1

chr3_-_23406964 1.13 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr5_-_29750377 1.12 ENSDART00000051474
barhl1a
BarH-like homeobox 1a
chr16_+_30301539 1.12 ENSDART00000186018
LO017848.1

chr7_+_32722227 1.11 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr9_+_46644633 1.10 ENSDART00000160285
slc4a3
solute carrier family 4 (anion exchanger), member 3
chr18_-_26510545 1.09 ENSDART00000135133
FRMD5
si:ch211-69m14.1
chr6_-_32349153 1.09 ENSDART00000140004
angptl3
angiopoietin-like 3
chr20_-_44575103 1.08 ENSDART00000192573
ubxn2a
UBX domain protein 2A
chr1_+_20069535 1.08 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr21_+_9576176 1.07 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mapk10
mitogen-activated protein kinase 10
chr4_-_4507761 1.07 ENSDART00000130588
tbc1d30
TBC1 domain family, member 30
chr7_-_52842007 1.06 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr24_-_30091937 1.06 ENSDART00000148249
plppr4b
phospholipid phosphatase related 4b
chr21_-_17482465 1.04 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr15_+_47418565 1.04 ENSDART00000155709
clpb
ClpB homolog, mitochondrial AAA ATPase chaperonin
chr15_-_26686908 1.04 ENSDART00000185254
pitpnm3
PITPNM family member 3
chr20_+_405811 1.03 ENSDART00000149311
gpr63
G protein-coupled receptor 63
chr9_+_32358514 1.03 ENSDART00000144608
plcl1
phospholipase C like 1
chr19_-_8880688 1.02 ENSDART00000039629
celf3a
cugbp, Elav-like family member 3a
chr24_-_21674950 1.01 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr15_-_5467477 1.01 ENSDART00000123839
arrb1
arrestin, beta 1
chr23_-_44494401 1.01 ENSDART00000114640
ENSDART00000148532
actl6b
actin-like 6B
chr16_-_24518027 1.00 ENSDART00000134120
ENSDART00000143761
cadm4
cell adhesion molecule 4
chr5_+_3501859 0.98 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr3_+_43467595 0.98 ENSDART00000188300
galr2b
galanin receptor 2b
chr19_+_27479563 0.97 ENSDART00000049368
ENSDART00000185426
atat1
alpha tubulin acetyltransferase 1
chr19_+_9533008 0.95 ENSDART00000104607
fam131ba
family with sequence similarity 131, member Ba
chr2_-_31735142 0.95 ENSDART00000130903
ralyl
RALY RNA binding protein like
chr17_-_35076730 0.94 ENSDART00000146590
mboat2a
membrane bound O-acyltransferase domain containing 2a
chr25_-_3979288 0.94 ENSDART00000157117
myrf
myelin regulatory factor
chr9_+_11034314 0.94 ENSDART00000032695
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr20_-_39273987 0.91 ENSDART00000127173
clu
clusterin
chr5_-_63515210 0.90 ENSDART00000022348
prdm12b
PR domain containing 12b
chr9_+_22632126 0.90 ENSDART00000139434
etv5a
ets variant 5a
chr16_+_10346277 0.89 ENSDART00000081092
si:dkeyp-77h1.4
si:dkeyp-77h1.4
chr18_-_42313798 0.88 ENSDART00000098639
cntn5
contactin 5
chr18_-_20816103 0.86 ENSDART00000143233
cttnbp2
cortactin binding protein 2
chr5_-_52277643 0.85 ENSDART00000010757
rgmb
repulsive guidance molecule family member b
chr1_+_19930520 0.85 ENSDART00000158344
apbb2b
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr17_-_10249095 0.81 ENSDART00000159963
sstr1a
somatostatin receptor 1a
chr14_-_2933185 0.80 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr1_+_2712956 0.79 ENSDART00000126093
gpc6a
glypican 6a
chr13_+_31070181 0.78 ENSDART00000110560
ENSDART00000146088
si:ch211-223a10.1
si:ch211-223a10.1
chr7_+_33314925 0.78 ENSDART00000148590
coro2ba
coronin, actin binding protein, 2Ba
chr14_+_8127893 0.77 ENSDART00000169091
psd2
pleckstrin and Sec7 domain containing 2
chr4_+_20318127 0.77 ENSDART00000028856
ENSDART00000132909
cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr16_-_26435431 0.76 ENSDART00000187526
megf8
multiple EGF-like-domains 8
chr22_+_17359346 0.76 ENSDART00000145434
gpr52
G protein-coupled receptor 52
chr7_-_54217547 0.76 ENSDART00000162777
ENSDART00000188268
ENSDART00000165875
csnk1g1
casein kinase 1, gamma 1
chr1_-_44704261 0.76 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr15_-_26636826 0.76 ENSDART00000087632
slc47a4
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr7_-_12789251 0.75 ENSDART00000052750
adamtsl3
ADAMTS-like 3
chr1_+_49814942 0.75 ENSDART00000164936
lef1
lymphoid enhancer-binding factor 1
chr16_+_55168245 0.75 ENSDART00000171109
eomesb
eomesodermin homolog b
chr2_-_2096055 0.75 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr3_-_47876427 0.75 ENSDART00000180844
ENSDART00000124480
adgrl1a
adhesion G protein-coupled receptor L1a
chr18_-_44611252 0.74 ENSDART00000173095
spred3
sprouty-related, EVH1 domain containing 3
chr15_+_17441734 0.74 ENSDART00000153729
snx19b
sorting nexin 19b
chr3_-_55531450 0.72 ENSDART00000155376
tex2
testis expressed 2
chr19_-_17526735 0.71 ENSDART00000189391
thrb
thyroid hormone receptor beta
chr16_+_52105227 0.71 ENSDART00000150025
ENSDART00000097863
MAN1C1
si:ch73-373m9.1
chr15_-_1003553 0.71 ENSDART00000154195
si:dkey-77f5.6
si:dkey-77f5.6
chr19_+_27479838 0.70 ENSDART00000103922
atat1
alpha tubulin acetyltransferase 1
chr12_-_25065916 0.69 ENSDART00000159167
socs5a
suppressor of cytokine signaling 5a
chr3_+_39853788 0.69 ENSDART00000154869
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr22_+_110158 0.68 ENSDART00000143698
prkar2ab
protein kinase, cAMP-dependent, regulatory, type II, alpha, B
chr16_-_39900665 0.68 ENSDART00000136719
rbms3
RNA binding motif, single stranded interacting protein
chr8_-_16259063 0.67 ENSDART00000057590
dmrta2
DMRT-like family A2
chr21_-_31143903 0.67 ENSDART00000111571
rap1gap2b
RAP1 GTPase activating protein 2b
chr13_+_42406883 0.66 ENSDART00000084354
cpeb3
cytoplasmic polyadenylation element binding protein 3
chr7_+_57725708 0.65 ENSDART00000056466
ENSDART00000142259
ENSDART00000166198
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr20_-_50014936 0.65 ENSDART00000148892
extl3
exostosin-like glycosyltransferase 3
chr11_+_6819050 0.63 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr20_-_7000225 0.63 ENSDART00000100098
adcy1a
adenylate cyclase 1a
chr11_+_43114108 0.62 ENSDART00000013642
ENSDART00000190266
foxg1b
forkhead box G1b
chr1_-_25438737 0.62 ENSDART00000134470
fhdc1
FH2 domain containing 1
chr9_+_54417141 0.61 ENSDART00000056810
drd1b
dopamine receptor D1b
chr2_+_21486529 0.61 ENSDART00000047468
inhbab
inhibin, beta Ab
chr18_-_12612699 0.61 ENSDART00000090335
hipk2
homeodomain interacting protein kinase 2
chr18_-_37007061 0.61 ENSDART00000136432
map3k10
mitogen-activated protein kinase kinase kinase 10
chr20_-_20931197 0.60 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr16_-_21181128 0.60 ENSDART00000133403
pde11al
phosphodiesterase 11a, like
chr2_+_38881165 0.59 ENSDART00000141850
carmil3
capping protein regulator and myosin 1 linker 3
chr3_-_61205711 0.58 ENSDART00000055062
pvalb1
parvalbumin 1
chr6_-_18739519 0.57 ENSDART00000170998
tnrc6c2
trinucleotide repeat containing 6C2
chr7_+_72460911 0.57 ENSDART00000160682
ENSDART00000168532
HECTD4
HECT domain E3 ubiquitin protein ligase 4
chr18_-_37007294 0.57 ENSDART00000088309
map3k10
mitogen-activated protein kinase kinase kinase 10
chr25_-_31118923 0.56 ENSDART00000009126
ENSDART00000188286
kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr17_-_50233493 0.56 ENSDART00000172266
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr11_-_17713987 0.55 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr14_+_11762991 0.54 ENSDART00000110004
frmpd3
FERM and PDZ domain containing 3
chr18_-_370286 0.54 ENSDART00000162633
si:ch211-79l17.1
si:ch211-79l17.1
chr21_+_1324416 0.53 ENSDART00000176557
TCF4
transcription factor 4
chr16_-_40727455 0.53 ENSDART00000162331
si:dkey-22o22.2
si:dkey-22o22.2
chr9_+_36356740 0.52 ENSDART00000139033
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr15_-_14375452 0.52 ENSDART00000160675
ENSDART00000164028
ENSDART00000171642
dpf1
D4, zinc and double PHD fingers family 1
chr16_+_23960744 0.52 ENSDART00000058965
apoeb
apolipoprotein Eb
chr2_+_35806672 0.52 ENSDART00000137384
rasal2
RAS protein activator like 2
chr7_+_28006096 0.51 ENSDART00000173843
tub
tubby bipartite transcription factor
chr12_+_38770654 0.50 ENSDART00000155367
kif19
kinesin family member 19
chr13_-_33000649 0.50 ENSDART00000133677
rbm25a
RNA binding motif protein 25a
chr9_+_37754845 0.50 ENSDART00000100592
pdia5
protein disulfide isomerase family A, member 5
chr8_-_40555340 0.49 ENSDART00000163348
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr16_-_46393154 0.49 ENSDART00000132154
si:ch73-59c19.1
si:ch73-59c19.1
chr24_-_35707552 0.49 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr1_+_41498697 0.48 ENSDART00000114230
dtx4
deltex 4, E3 ubiquitin ligase
chr2_+_56463167 0.48 ENSDART00000123392
rab11bb
RAB11B, member RAS oncogene family, b
chr5_-_22952156 0.48 ENSDART00000111146
si:ch211-26b3.4
si:ch211-26b3.4
chr14_-_33083539 0.48 ENSDART00000160173
dlg3
discs, large homolog 3 (Drosophila)
chr1_+_44710955 0.48 ENSDART00000131296
ENSDART00000142187
ssrp1b
structure specific recognition protein 1b
chr6_-_4214297 0.47 ENSDART00000191433
trak2
trafficking protein, kinesin binding 2
chr12_+_22407852 0.47 ENSDART00000178840
hdlbpb
high density lipoprotein binding protein b
chr10_-_309894 0.46 ENSDART00000163287
CABZ01049607.1

chr16_+_25116827 0.45 ENSDART00000163244
si:ch211-261d7.6
si:ch211-261d7.6
chr20_-_39273505 0.45 ENSDART00000153114
clu
clusterin
chr1_-_10071422 0.45 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr5_+_19165949 0.44 ENSDART00000140710
unc13ba
unc-13 homolog Ba (C. elegans)
chr10_+_44057502 0.44 ENSDART00000183868
grk3
G protein-coupled receptor kinase 3
chr2_+_45300512 0.43 ENSDART00000144704
camsap2b
calmodulin regulated spectrin-associated protein family, member 2b
chr6_+_37754763 0.43 ENSDART00000110770
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr11_+_18873113 0.42 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr8_-_22157301 0.42 ENSDART00000158383
nphp4
nephronophthisis 4
chr16_+_23960933 0.42 ENSDART00000146077
apoeb
apolipoprotein Eb
chr5_+_50788329 0.42 ENSDART00000050979
fam81b
family with sequence similarity 81, member B
chr10_+_44057177 0.42 ENSDART00000164610
grk3
G protein-coupled receptor kinase 3
chr15_-_23442891 0.41 ENSDART00000059376
ube4a
ubiquitination factor E4A (UFD2 homolog, yeast)
chr20_+_20731052 0.41 ENSDART00000047662
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr7_-_31938938 0.40 ENSDART00000132353
bdnf
brain-derived neurotrophic factor
chr5_-_201600 0.40 ENSDART00000158495
CABZ01088906.1

chr18_+_3498989 0.40 ENSDART00000172373
ompa
olfactory marker protein a
chr4_+_77920666 0.40 ENSDART00000129523
ttll1
tubulin tyrosine ligase-like family, member 1
chr3_-_55649319 0.39 ENSDART00000176127
axin2
axin 2 (conductin, axil)

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut1+onecutl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.5 2.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 1.6 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.5 1.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.7 GO:0007624 ultradian rhythm(GO:0007624)
0.3 1.6 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.3 0.9 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 3.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.3 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 1.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.3 1.0 GO:1900120 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 2.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 0.6 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 3.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 3.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 0.7 GO:0046552 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.2 1.0 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.8 GO:0014896 muscle hypertrophy(GO:0014896)
0.2 0.8 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.1 1.5 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.7 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.6 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 0.1 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 4.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 1.0 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 0.9 GO:0043217 myelin maintenance(GO:0043217)
0.1 1.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 1.6 GO:0048899 anterior lateral line development(GO:0048899)
0.1 0.3 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.0 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 0.3 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.5 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.9 GO:0003315 heart rudiment formation(GO:0003315)
0.1 1.4 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.4 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.3 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.6 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.1 1.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.5 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.8 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 4.3 GO:0007254 JNK cascade(GO:0007254)
0.1 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0021982 pineal gland development(GO:0021982)
0.0 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 3.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 1.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.4 GO:0021576 hindbrain formation(GO:0021576)
0.0 0.8 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 1.0 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.6 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.4 GO:1901214 regulation of neuron death(GO:1901214)
0.0 4.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.7 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.7 GO:0006475 internal protein amino acid acetylation(GO:0006475) internal peptidyl-lysine acetylation(GO:0018393)
0.0 2.9 GO:0051260 protein homooligomerization(GO:0051260)
0.0 2.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0021634 optic nerve formation(GO:0021634)
0.0 6.1 GO:0007411 axon guidance(GO:0007411)
0.0 0.7 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 1.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993) vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) negative regulation of systemic arterial blood pressure(GO:0003085) vasodilation(GO:0042311)
0.0 0.7 GO:0035336 long-chain fatty acid metabolic process(GO:0001676) long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 1.6 GO:0036293 response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293)
0.0 0.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0061138 morphogenesis of a branching epithelium(GO:0061138)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 1.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.5 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.1 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 1.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.3 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 1.6 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0060077 inhibitory synapse(GO:0060077)
0.5 3.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 1.6 GO:0033010 paranodal junction(GO:0033010)
0.2 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.8 GO:1990071 TRAPPII protein complex(GO:1990071)
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 6.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.4 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.0 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.7 GO:0043679 axon terminus(GO:0043679)
0.0 1.7 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 1.3 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 3.4 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 2.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.5 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 1.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 8.3 GO:0043005 neuron projection(GO:0043005)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.5 1.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.5 3.0 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 1.4 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.3 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 3.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.7 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 3.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 0.6 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 2.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 1.0 GO:0004966 galanin receptor activity(GO:0004966)
0.1 2.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.3 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 4.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 1.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 2.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.4 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 1.7 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 2.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits