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PRJNA207719: Tissue specific transcriptome profiling

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Results for osr2

Z-value: 0.61

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Transcription factors associated with osr2

Gene Symbol Gene ID Gene Info
osr2
ENSDARG00000038006 odd-skipped related transciption factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
osr2dr11_v1_chr16_-_54405976_544059760.741.6e-01Click!

Activity profile of osr2 motif

Sorted Z-values of osr2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_29418620 0.34 ENSDART00000172634
ryr3
ryanodine receptor 3
chr7_+_42206543 0.26 ENSDART00000112543
phkb
phosphorylase kinase, beta
chr22_-_28871787 0.22 ENSDART00000104828
gtpbp2b
GTP binding protein 2b
chr14_+_36246726 0.21 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr15_-_39848822 0.20 ENSDART00000155230
si:dkey-263j23.1
si:dkey-263j23.1
chr14_+_23717165 0.19 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr13_+_30696286 0.18 ENSDART00000192411
cxcl18a.1
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr18_-_27316599 0.18 ENSDART00000028294
zgc:56106
zgc:56106
chr3_-_28120092 0.18 ENSDART00000151143
rbfox1
RNA binding fox-1 homolog 1
chr19_-_25519310 0.17 ENSDART00000089882
C1GALT1 (1 of many)
si:dkey-202e17.1
chr5_+_13373593 0.17 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr20_+_30490682 0.16 ENSDART00000184871
myt1la
myelin transcription factor 1-like, a
chr6_+_46431848 0.15 ENSDART00000181056
ENSDART00000144569
ENSDART00000064865
ENSDART00000133992
stau1
staufen double-stranded RNA binding protein 1
chr19_-_25519612 0.15 ENSDART00000133150
C1GALT1 (1 of many)
si:dkey-202e17.1
chr7_+_42206847 0.15 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr6_+_54576520 0.15 ENSDART00000093199
ENSDART00000127519
ENSDART00000157142
tead3b
TEA domain family member 3 b
chr23_+_36095260 0.14 ENSDART00000127384
hoxc9a
homeobox C9a
chr7_-_42206720 0.13 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr12_-_38548299 0.13 ENSDART00000153374
si:dkey-1f1.3
si:dkey-1f1.3
chr5_-_48307804 0.12 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb
chr19_-_6134802 0.11 ENSDART00000140051
cica
capicua transcriptional repressor a
chr8_+_10835456 0.11 ENSDART00000151388
mapk13
mitogen-activated protein kinase 13
chr18_-_39200557 0.11 ENSDART00000132367
ENSDART00000183672
si:ch211-235f12.2
mapk6
si:ch211-235f12.2
mitogen-activated protein kinase 6
chr3_+_25907266 0.10 ENSDART00000170324
ENSDART00000192633
tom1
target of myb1 membrane trafficking protein
chr10_+_38512270 0.10 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr16_-_13680692 0.10 ENSDART00000047452
ube2s
ubiquitin-conjugating enzyme E2S
chr14_+_48964628 0.09 ENSDART00000105427
mif
macrophage migration inhibitory factor
chr12_+_28856151 0.09 ENSDART00000152969
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr6_-_40884453 0.09 ENSDART00000017968
ENSDART00000154100
sirt4
sirtuin 4
chr21_-_25250594 0.07 ENSDART00000163862
nfrkb
nuclear factor related to kappaB binding protein
chr7_+_38090515 0.07 ENSDART00000131387
cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr3_-_32958505 0.06 ENSDART00000147374
ENSDART00000136919
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr19_-_9503473 0.06 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr13_+_29778610 0.06 ENSDART00000132004
pax2a
paired box 2a
chr18_-_46010 0.05 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_+_35344031 0.04 ENSDART00000167140
si:dkey-34d22.1
si:dkey-34d22.1
chr11_+_31285127 0.03 ENSDART00000160154
si:dkey-238i5.2
si:dkey-238i5.2
chr18_-_45736 0.03 ENSDART00000148373
ENSDART00000148950
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr23_-_36003282 0.02 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr25_-_19395476 0.02 ENSDART00000182622
map1ab
microtubule-associated protein 1Ab
chr13_-_27621246 0.02 ENSDART00000102232
kcnq5a
potassium voltage-gated channel, KQT-like subfamily, member 5a
chr8_-_22639794 0.02 ENSDART00000188029
iqsec2a
IQ motif and Sec7 domain 2a
chr2_+_5446882 0.02 ENSDART00000083260
dusp28
dual specificity phosphatase 28
chr2_+_3986083 0.02 ENSDART00000188979
mkxb
mohawk homeobox b
chr16_-_13612650 0.01 ENSDART00000080372
dbpb
D site albumin promoter binding protein b
chr10_-_13239367 0.01 ENSDART00000001253
si:busm1-57f23.1
si:busm1-57f23.1

Network of associatons between targets according to the STRING database.

First level regulatory network of osr2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions