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PRJNA207719: Tissue specific transcriptome profiling

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Results for otx2b

Z-value: 1.11

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Transcription factors associated with otx2b

Gene Symbol Gene ID Gene Info
ENSDARG00000011235 orthodenticle homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx2bdr11_v1_chr17_-_44249720_442497200.968.9e-03Click!

Activity profile of otx2b motif

Sorted Z-values of otx2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_34220194 1.67 ENSDART00000145859
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23b
chr22_+_5103349 1.50 ENSDART00000083474
ataxia, cerebellar, Cayman type a
chr16_+_32059785 1.30 ENSDART00000134459
si:dkey-40m6.8
chr17_-_12389259 1.07 ENSDART00000185724
synaptosomal-associated protein, 25b
chr14_-_36378494 1.06 ENSDART00000058503
glycoprotein M6Aa
chr16_-_33059246 0.95 ENSDART00000171718
ENSDART00000168305
ENSDART00000166401
synaptosomal-associated protein 91
chr3_+_34919810 0.95 ENSDART00000055264
carbonic anhydrase Xb
chr15_+_33070939 0.84 ENSDART00000164928
mab-21-like 1
chr11_-_29082175 0.82 ENSDART00000123245
immunoglobin superfamily, member 21a
chr12_-_10275320 0.79 ENSDART00000170078
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr11_-_29082429 0.79 ENSDART00000041443
immunoglobin superfamily, member 21a
chr11_+_39672874 0.75 ENSDART00000046663
ENSDART00000157659
calmodulin binding transcription activator 1b
chr15_-_18574716 0.75 ENSDART00000142010
ENSDART00000019006
neural cell adhesion molecule 1b
chr15_-_26636826 0.75 ENSDART00000087632
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr6_+_36942966 0.74 ENSDART00000028895
neuronal growth regulator 1
chr21_-_28235361 0.73 ENSDART00000164458
neurexin 2a
chr11_-_4235811 0.69 ENSDART00000121716
si:ch211-236d3.4
chr7_-_49594995 0.64 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr5_-_28606916 0.64 ENSDART00000026107
ENSDART00000137717
tenascin C
chr10_-_21054059 0.64 ENSDART00000139733
protocadherin 1a
chr14_-_4273396 0.63 ENSDART00000127318
FERM and PDZ domain containing 1b
chr5_-_28625515 0.62 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tenascin C
chr9_+_13714379 0.62 ENSDART00000017593
ENSDART00000145503
transmembrane protein 237a
chr19_-_9503473 0.61 ENSDART00000091615
intermediate filament family orphan 1a
chr24_+_24923166 0.61 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr21_+_32338897 0.61 ENSDART00000110137
si:ch211-247j9.1
chr13_-_36184701 0.59 ENSDART00000146522
mitogen-activated protein kinase kinase kinase 9
chr14_-_30587814 0.59 ENSDART00000144912
ENSDART00000149714
transmembrane protein 265
chr2_-_30784198 0.59 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr17_+_35097024 0.58 ENSDART00000026152
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr17_-_20979077 0.58 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr23_-_7125494 0.57 ENSDART00000111929
solute carrier organic anion transporter family, member 4A1
chr21_-_40782393 0.56 ENSDART00000075808
amyloid beta (A4) precursor protein-binding, family B, member 3
chr19_-_8880688 0.56 ENSDART00000039629
cugbp, Elav-like family member 3a
chr2_+_25929619 0.54 ENSDART00000137746
solute carrier family 7, member 14a
chr22_+_438714 0.53 ENSDART00000136491
cadherin, EGF LAG seven-pass G-type receptor 2
chr7_+_30970045 0.52 ENSDART00000155974
tight junction protein 1a
chr3_-_28665291 0.52 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr3_+_1492174 0.51 ENSDART00000112979
SRY (sex determining region Y)-box 10
chr3_-_33574576 0.48 ENSDART00000184881

chr7_-_41489822 0.48 ENSDART00000006724
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr12_+_39685485 0.48 ENSDART00000163403

chr5_-_14390445 0.46 ENSDART00000026120
adaptor-related protein complex 3, mu 2 subunit
chr11_+_25010491 0.46 ENSDART00000167285
zgc:92107
chr13_-_36525982 0.45 ENSDART00000114744
phosphofurin acidic cluster sorting protein 2
chr12_+_25640480 0.45 ENSDART00000105608
protein kinase C, epsilon a
chr6_-_20875111 0.45 ENSDART00000115118
ENSDART00000159916
tensin 1a
chr7_-_41489997 0.45 ENSDART00000174300
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr14_+_34966598 0.45 ENSDART00000004550
ring finger protein 145a
chr12_+_41991635 0.44 ENSDART00000186161
ENSDART00000192510
transcription elongation regulator 1 like
chr10_+_29963518 0.44 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
neurotrimin
chr23_-_28294763 0.43 ENSDART00000139537
zinc finger protein 385A
chr1_-_39909985 0.43 ENSDART00000181673
storkhead box 2a
chr1_-_20273227 0.42 ENSDART00000146084
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr13_-_36184476 0.42 ENSDART00000057185
mitogen-activated protein kinase kinase kinase 9
chr7_-_52842605 0.41 ENSDART00000083002
microtubule-associated protein 1Aa
chr4_-_5077158 0.41 ENSDART00000155915
adenosylhomocysteinase-like 2
chr25_-_7925269 0.41 ENSDART00000014274
glucuronic acid epimerase a
chr18_+_10784730 0.41 ENSDART00000028938
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr17_+_25289431 0.41 ENSDART00000161002
kelch repeat and BTB (POZ) domain containing 11
chr1_-_17650223 0.41 ENSDART00000043484
si:dkey-256e7.5
chr21_+_32339158 0.40 ENSDART00000161723
si:ch211-247j9.1
chr2_-_1569250 0.40 ENSDART00000167202
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr12_+_15622621 0.40 ENSDART00000079784
phospholipase C, delta 3b
chr9_-_18568927 0.40 ENSDART00000084668
ecto-NOX disulfide-thiol exchanger 1
chr18_+_7639401 0.40 ENSDART00000092416
RAB, member of RAS oncogene family-like 2
chr1_-_16507812 0.40 ENSDART00000169081
myotubularin related protein 7b
chr25_-_7925019 0.39 ENSDART00000183309
glucuronic acid epimerase a
chr14_-_2400668 0.39 ENSDART00000172717
ENSDART00000182882
si:ch73-233f7.1
chr20_+_53278746 0.39 ENSDART00000074249
G protein-coupled receptor 6
chr5_+_43072951 0.38 ENSDART00000193905
ENSDART00000026020
WD repeat domain 54
chr14_-_2933185 0.37 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
chr20_-_20821783 0.36 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
creatine kinase, brain b
chr14_-_32503363 0.35 ENSDART00000034883
MCF.2 cell line derived transforming sequence a
chr2_+_30878864 0.35 ENSDART00000009326
opioid receptor, kappa 1
chr2_-_4797512 0.35 ENSDART00000160765
tyrosine kinase, non-receptor, 2b
chr3_-_61593274 0.35 ENSDART00000154132
ENSDART00000055071
neuronal pentraxin 2a
chr16_+_14710436 0.35 ENSDART00000027982
collagen, type XIV, alpha 1a
chr9_+_11034967 0.34 ENSDART00000152081
acid-sensing (proton-gated) ion channel family member 4a
chr6_+_32415132 0.33 ENSDART00000155790
KN motif and ankyrin repeat domains 4
chr2_+_28995776 0.31 ENSDART00000138733
cadherin 12, type 2a (N-cadherin 2)
chr17_+_18117029 0.30 ENSDART00000154646
ENSDART00000179739
B cell CLL/lymphoma 11Ba
chr25_-_19090479 0.30 ENSDART00000027465
ENSDART00000177670
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr16_+_11151699 0.30 ENSDART00000140674
capicua transcriptional repressor b
chr17_+_10593398 0.30 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr7_-_18656069 0.29 ENSDART00000021559
coronin, actin binding protein, 1B
chr10_+_4095917 0.28 ENSDART00000114533
meningioma 1a
chr10_-_7988396 0.27 ENSDART00000141445
ENSDART00000024282
EWS RNA-binding protein 1a
chr1_-_11075403 0.27 ENSDART00000102903
ENSDART00000170290
dystrophin
chr16_-_37372613 0.27 ENSDART00000124090
si:ch211-208k15.1
chr3_+_15296824 0.27 ENSDART00000043801
calcium binding protein 5b
chr7_+_66884291 0.26 ENSDART00000187499
SET binding factor 2
chr7_+_19904136 0.26 ENSDART00000173452
si:ch211-285j22.3
chr9_+_26103814 0.26 ENSDART00000026011
ephrin-B2a
chr5_+_34981584 0.24 ENSDART00000134795
ankyrin repeat, family A (RFXANK-like), 2
chr17_-_21617618 0.24 ENSDART00000109031
G protein-coupled receptor 26
chr11_-_27702778 0.24 ENSDART00000045942
ENSDART00000125352
PHD finger protein 2
chr5_+_59494079 0.24 ENSDART00000148727
GTF2I repeat domain containing 1
chrM_+_15308 0.23 ENSDART00000093625
cytochrome b, mitochondrial
chr24_-_1303935 0.23 ENSDART00000159212
ENSDART00000159267
ENSDART00000164904
neuropilin 1a
chr17_-_31058900 0.23 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
echinoderm microtubule associated protein like 1
chr20_-_9963713 0.23 ENSDART00000104234
gap junction protein delta 2b
chr13_+_31205439 0.22 ENSDART00000132326
protein tyrosine phosphatase, non-receptor type 20
chr1_+_33383644 0.22 ENSDART00000187194
dehydrogenase/reductase (SDR family) X-linked
chr24_+_3478871 0.22 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
WD repeat domain 37
chr7_+_19903924 0.22 ENSDART00000159112
si:ch211-285j22.3
chr7_+_39011852 0.22 ENSDART00000093009
diacylglycerol kinase, zeta a
chr11_-_29563437 0.22 ENSDART00000163958
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr10_-_25561751 0.22 ENSDART00000147089
glutamate receptor, ionotropic, kainate 1a
chr5_-_27994679 0.22 ENSDART00000132740
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr16_+_24684107 0.21 ENSDART00000183920
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr2_+_11923824 0.21 ENSDART00000153873
TROVE domain family, member 2
chr6_-_17999776 0.20 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
regulatory associated protein of MTOR, complex 1
chr2_+_31476065 0.20 ENSDART00000049219
calcium channel, voltage-dependent, beta 2b
chr24_-_18876877 0.19 ENSDART00000186269
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr13_-_47800342 0.19 ENSDART00000121817
fibulin 7
chr17_-_50010121 0.19 ENSDART00000122747
transmembrane protein 30Aa
chr4_-_9173552 0.19 ENSDART00000042963
carbohydrate (chondroitin 4) sulfotransferase 11
chr15_+_37559570 0.19 ENSDART00000085522
heat shock protein, alpha-crystallin-related, b6
chr25_+_33002963 0.19 ENSDART00000187366

chr7_+_39011355 0.19 ENSDART00000173855
diacylglycerol kinase, zeta a
chr23_-_27050083 0.18 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
chr11_-_3860199 0.18 ENSDART00000082420
GATA binding protein 2a
chr2_-_48171441 0.18 ENSDART00000123040
phosphofructokinase, platelet b
chr15_+_42599501 0.18 ENSDART00000177646
glutamate receptor, ionotropic, kainate 1b
chr7_-_64770456 0.18 ENSDART00000192618
zinc finger, DHHC-type containing 21
chr24_-_18877118 0.18 ENSDART00000092783
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr3_-_30885250 0.18 ENSDART00000109104
lysine methyltransferase 5C
chr7_+_57866292 0.17 ENSDART00000138757
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr7_+_38395197 0.17 ENSDART00000138669
centrosomal protein 89
chr20_-_34768301 0.17 ENSDART00000142482
progestin and adipoQ receptor family member VIII
chr11_-_3860534 0.17 ENSDART00000082425
GATA binding protein 2a
chr14_+_14847745 0.16 ENSDART00000189302
ENSDART00000188336
coiled-coil domain containing 142
chr25_+_29688671 0.16 ENSDART00000073478
bromodomain containing 1b
chr20_-_16548912 0.16 ENSDART00000137601
checkpoint suppressor 1
chr11_+_2506516 0.15 ENSDART00000130886
ENSDART00000189767
si:ch73-190f16.2
chr10_-_27199135 0.14 ENSDART00000189511
ENSDART00000180314
autism susceptibility candidate 2a
chr13_+_17468161 0.14 ENSDART00000008906
zinc finger protein 503
chr15_+_29116063 0.13 ENSDART00000016112
ENSDART00000153609
ENSDART00000155630
calpain, small subunit 1 b
chr12_-_35582683 0.13 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr25_-_16818195 0.13 ENSDART00000185215
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr5_-_17876709 0.13 ENSDART00000141978
si:dkey-112e17.1
chr11_-_40257225 0.13 ENSDART00000139009
si:ch211-193i15.2
chr7_+_66884570 0.13 ENSDART00000082664
SET binding factor 2
chr14_+_1124409 0.12 ENSDART00000190043
ENSDART00000106708
ENSDART00000160246
SEC24 homolog B, COPII coat complex component
chr12_+_6098713 0.12 ENSDART00000139054
sphingomyelin synthase 1
chr22_+_30184039 0.12 ENSDART00000049075
adducin 3 (gamma) a
chr25_-_16818380 0.12 ENSDART00000155401
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr14_+_14847304 0.12 ENSDART00000169932
coiled-coil domain containing 142
chr2_-_32513538 0.11 ENSDART00000056640
ATP-binding cassette, sub-family F (GCN20), member 2a
chr1_-_26293203 0.10 ENSDART00000180140
CXXC finger 4
chr2_-_48171112 0.10 ENSDART00000156258
phosphofructokinase, platelet b
chr8_+_14381272 0.10 ENSDART00000057642
acyl-CoA binding domain containing 6
chr9_-_8454060 0.10 ENSDART00000110158
insulin receptor substrate 2b
chr5_+_37290260 0.10 ENSDART00000113642
zgc:163098
chr21_-_27251112 0.10 ENSDART00000137667
MAP/microtubule affinity-regulating kinase 2a
chr14_+_5861435 0.09 ENSDART00000041279
ENSDART00000147341
tubulin, beta 4B class IVb
chr19_-_2115040 0.08 ENSDART00000020497
sorting nexin 13
chr12_-_10508952 0.07 ENSDART00000152806
zgc:152977
chr2_-_16217344 0.07 ENSDART00000152031
Rho guanine nucleotide exchange factor (GEF) 4
chr3_-_32170850 0.07 ENSDART00000055307
ENSDART00000157366
troponin T type 1 (skeletal, slow)
chr1_+_44523516 0.07 ENSDART00000147702
zinc finger, DHHC-type containing 5a
chr24_+_37533728 0.06 ENSDART00000061203
ras homolog family member T2
chr20_+_16721933 0.06 ENSDART00000063950
proteasome 26S subunit, ATPase 1b
chr5_+_63767376 0.06 ENSDART00000138898
regulator of G protein signaling 3b
chr19_+_43884120 0.06 ENSDART00000139684
ENSDART00000142312
lysophospholipase II
chr16_+_16265850 0.06 ENSDART00000181265
SET domain containing 2
chr14_-_46395408 0.06 ENSDART00000147537
Bardet-Biedl syndrome 7
chr23_-_27152866 0.06 ENSDART00000141305
si:dkey-157g16.6
chr10_-_18468385 0.06 ENSDART00000183302
si:dkey-28o19.1
chr12_-_35582521 0.06 ENSDART00000162175
ENSDART00000168958
SEC24 homolog C, COPII coat complex component
chr13_-_50614639 0.06 ENSDART00000170527
ventral expressed homeobox
chr13_+_1089942 0.05 ENSDART00000054322
cannabinoid receptor interacting protein 1b
chr12_+_33460794 0.05 ENSDART00000007053
ENSDART00000142716
nuclear prelamin A recognition factor
chr8_-_25566347 0.05 ENSDART00000138289
ENSDART00000078022
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr15_-_15469079 0.05 ENSDART00000132637
ENSDART00000004220
RAB34, member RAS oncogene family a
chr20_-_1141722 0.05 ENSDART00000152675
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr12_+_11080776 0.05 ENSDART00000079336
retinoic acid receptor, alpha a
chr6_+_36795225 0.05 ENSDART00000171504
si:ch73-29l19.1
chr20_-_34754617 0.05 ENSDART00000148066
zinc finger protein 395b
chr18_+_9323211 0.05 ENSDART00000166114
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr11_-_16215143 0.05 ENSDART00000027014
RAB7, member RAS oncogene family
chr25_+_19753890 0.04 ENSDART00000190268
ENSDART00000128852
cadherin EGF LAG seven-pass G-type receptor 1b
chr2_-_50272077 0.04 ENSDART00000127623
cullin 1a
chr15_-_38154616 0.04 ENSDART00000099392
immunity-related GTPase family, q2
chr10_-_3394256 0.03 ENSDART00000158315
ENSDART00000111241
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr6_-_36795111 0.03 ENSDART00000160669
ENSDART00000104256
ENSDART00000187751
ENSDART00000161928
ENSDART00000183264
optic atrophy 1 (autosomal dominant)
chr18_+_49969568 0.03 ENSDART00000126916
MOB kinase activator 2b
chr8_+_20503842 0.03 ENSDART00000100328
casein kinase 1, gamma 2b
chr2_-_38337122 0.03 ENSDART00000076523
ENSDART00000187473
solute carrier family 7 (amino acid transporter light chain, L system), member 8b
chr9_-_32343673 0.03 ENSDART00000078499
raftlin family member 2
chr11_+_30296332 0.02 ENSDART00000192843
UDP glucuronosyltransferase 1 family, polypeptide B7
chr16_+_42829735 0.02 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr1_+_55080797 0.01 ENSDART00000077390
lectin, galactoside-binding-like a
chr10_+_35554219 0.01 ENSDART00000077373
zinc finger, DHHC-type containing 20a
chr7_-_17780048 0.01 ENSDART00000183336
si:dkey-106g10.7
chr14_+_21754521 0.00 ENSDART00000111839
lysine (K)-specific demethylase 2Ab
chr14_-_32089117 0.00 ENSDART00000158014
si:ch211-69b22.5

Network of associatons between targets according to the STRING database.

First level regulatory network of otx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.2 1.0 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 1.5 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.3 GO:0061614 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.9 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 1.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.4 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.2 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.4 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 1.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 1.0 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.5 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.5 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 1.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.3 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.9 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.0 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 1.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.7 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction