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PRJNA207719: Tissue specific transcriptome profiling

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Results for pax2a+pax5

Z-value: 3.03

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Transcription factors associated with pax2a+pax5

Gene Symbol Gene ID Gene Info
ENSDARG00000028148 paired box 2a
ENSDARG00000037383 paired box 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax2adr11_v1_chr13_+_29778610_297786100.932.1e-02Click!
pax5dr11_v1_chr1_+_21731382_217313820.405.1e-01Click!

Activity profile of pax2a+pax5 motif

Sorted Z-values of pax2a+pax5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_12034444 2.74 ENSDART00000038651
zinc finger protein 804A
chr19_-_103289 2.43 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr5_+_36974931 2.18 ENSDART00000193063
gap junction protein delta 1a
chr14_+_50770537 1.98 ENSDART00000158723
synuclein, beta
chr5_+_38276582 1.77 ENSDART00000158532
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr11_-_44543082 1.74 ENSDART00000099568
G protein-coupled receptor 137Bb
chr3_-_46818001 1.70 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr14_-_36378494 1.63 ENSDART00000058503
glycoprotein M6Aa
chr8_-_23416362 1.60 ENSDART00000063005
G protein-coupled receptor 173
chr16_-_27628994 1.57 ENSDART00000157407
NAC alpha domain containing
chr13_-_9318891 1.57 ENSDART00000137364
si:dkey-33c12.3
chr9_+_38962017 1.55 ENSDART00000140436
microtubule-associated protein 2
chr14_+_22172047 1.54 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr1_+_14283692 1.47 ENSDART00000017679
protein phosphatase 2, regulatory subunit B, gamma a
chr3_-_1317290 1.45 ENSDART00000047094

chr21_+_19008168 1.43 ENSDART00000136196
ENSDART00000128381
ENSDART00000176624
neurofilament, light polypeptide a
chr13_-_226109 1.43 ENSDART00000161705
ENSDART00000172744
ENSDART00000163902
ENSDART00000158208
reticulon 4b
chr23_-_26522760 1.42 ENSDART00000142417
ENSDART00000135606
ENSDART00000122668
si:dkey-205h13.1
chr2_-_9646857 1.37 ENSDART00000056901
zgc:153615
chr7_+_30787903 1.37 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr12_-_35787801 1.36 ENSDART00000171682
apoptosis-associated tyrosine kinase b
chr10_-_17103651 1.36 ENSDART00000108959
ring finger protein 208
chr3_-_46817838 1.36 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr2_-_42864472 1.34 ENSDART00000134139
adenylate cyclase 8 (brain)
chr18_+_9635178 1.30 ENSDART00000183486
piccolo presynaptic cytomatrix protein b
chr6_-_14139503 1.30 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr3_-_22191132 1.28 ENSDART00000154226
ENSDART00000155528
ENSDART00000155190
microtubule-associated protein tau b
chr7_+_72882446 1.24 ENSDART00000131113
ENSDART00000174223
adhesion G protein-coupled receptor L3
chr15_-_16098531 1.23 ENSDART00000080377
aldolase C, fructose-bisphosphate, a
chr16_+_39146696 1.23 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr17_-_15528597 1.23 ENSDART00000150232
FYN proto-oncogene, Src family tyrosine kinase a
chr2_-_56385373 1.22 ENSDART00000169101
ceramide synthase 4b
chr8_-_21268303 1.22 ENSDART00000067211
G protein-coupled receptor 37 like 1b
chr25_+_6306885 1.21 ENSDART00000142705
ENSDART00000067510
cellular retinoic acid binding protein 1a
chr8_+_28065803 1.18 ENSDART00000178481
potassium voltage-gated channel, Shal-related subfamily, member 3
chr10_+_34394454 1.16 ENSDART00000110121
StAR-related lipid transfer (START) domain containing 13a
chr7_+_60551133 1.15 ENSDART00000148038
leucine rich repeat and fibronectin type III domain containing 4b
chr25_-_225964 1.14 ENSDART00000193424

chr21_-_27010796 1.14 ENSDART00000065398
ENSDART00000144342
ENSDART00000126542
protein phosphatase 1, regulatory (inhibitor) subunit 14Ba
chr7_+_29951997 1.12 ENSDART00000173453
alpha-tropomyosin
chr9_-_7421135 1.12 ENSDART00000144600
bridging integrator 1a
chr23_-_29502287 1.11 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr3_+_7617353 1.11 ENSDART00000165551
zgc:109949
chr23_+_40461411 1.11 ENSDART00000184223
SOGA family member 3b
chr9_+_17787864 1.11 ENSDART00000013111
diacylglycerol kinase, eta
chr25_+_33192796 1.11 ENSDART00000125892
ENSDART00000121680
ENSDART00000014851
zgc:171719
chr1_-_21409877 1.09 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr4_+_21129752 1.08 ENSDART00000169764
synaptotagmin Ia
chr8_+_23165749 1.08 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr23_+_45579497 1.07 ENSDART00000110381
early growth response 4
chr15_-_23342752 1.07 ENSDART00000020425
melanoma cell adhesion molecule b
chr11_-_103136 1.07 ENSDART00000173308
ENSDART00000162982
engulfment and cell motility 2
chr2_-_44283554 1.06 ENSDART00000184684
myelin protein zero
chr4_-_2162688 1.05 ENSDART00000148900
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr19_-_3240605 1.04 ENSDART00000105168
si:ch211-133n4.4
chr4_+_26628822 1.03 ENSDART00000191030
ENSDART00000186113
ENSDART00000186764
ENSDART00000165158
IQ motif and Sec7 domain 3a
chr7_+_29952169 1.01 ENSDART00000173540
ENSDART00000173940
ENSDART00000173906
ENSDART00000173772
ENSDART00000173506
ENSDART00000039657
alpha-tropomyosin
chr18_-_50862939 0.99 ENSDART00000180407

chr12_+_18606140 0.99 ENSDART00000161128
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, b
chr19_+_206835 0.99 ENSDART00000161137
sodium channel, voltage-gated, type I, beta b
chr3_-_22212764 0.99 ENSDART00000155490
microtubule-associated protein tau b
chr8_+_9867864 0.98 ENSDART00000188610
potassium voltage-gated channel, Shal-related subfamily, member 1
chr7_-_56793739 0.98 ENSDART00000082842
si:ch211-146m13.3
chr16_-_13730152 0.97 ENSDART00000138772
tweety family member 1
chr3_-_24980067 0.97 ENSDART00000048871
desumoylating isopeptidase 1a
chr10_+_466926 0.97 ENSDART00000145220
ARVCF, delta catenin family member a
chr2_-_5074812 0.97 ENSDART00000163728
discs, large (Drosophila) homolog 1, like
chr6_-_13187168 0.97 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr1_-_29045426 0.96 ENSDART00000019770
glycoprotein M6Ba
chr9_+_42066030 0.95 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr12_-_19103490 0.95 ENSDART00000060561
cold shock domain containing C2, RNA binding a
chr11_-_45171139 0.95 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
synaptogyrin 2b
chr23_+_9035578 0.94 ENSDART00000140455
cerebral cavernous malformation 2-like
chr2_+_58221163 0.94 ENSDART00000157939

chr5_-_22501663 0.93 ENSDART00000133174
si:dkey-27p18.5
chr19_+_31771270 0.93 ENSDART00000147474
stathmin 2b
chr13_+_4405282 0.92 ENSDART00000148280
proline rich 18
chr6_-_14040136 0.91 ENSDART00000065361
ENSDART00000179765
ets variant 5b
chr17_-_22048233 0.91 ENSDART00000155203
tau tubulin kinase 1b
chr7_-_23996133 0.91 ENSDART00000173761
si:dkey-183c6.8
chr20_+_19238382 0.91 ENSDART00000136757
fibronectin type III domain containing 4a
chr19_-_21716593 0.91 ENSDART00000155126
zinc finger protein 516
chr11_-_37509001 0.90 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr13_-_27675212 0.90 ENSDART00000141035
regulating synaptic membrane exocytosis 1a
chr17_+_26569601 0.90 ENSDART00000153897
neuron-derived neurotrophic factor , like
chr7_-_29625509 0.90 ENSDART00000173723
RAR-related orphan receptor A, paralog b
chr11_+_23957440 0.89 ENSDART00000190721
contactin 2
chr7_+_21768452 0.89 ENSDART00000127719
lysine (K)-specific demethylase 6B, a
chr24_+_3963684 0.89 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
phosphofructokinase, platelet a
chr21_+_5209716 0.88 ENSDART00000102539
ENSDART00000053148
ENSDART00000102536
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr3_-_28250722 0.88 ENSDART00000165936
RNA binding fox-1 homolog 1
chr2_-_40135942 0.88 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
eph receptor A4a
chr20_-_54462551 0.87 ENSDART00000171769
ENSDART00000169692
Enah/Vasp-like b
chr8_+_31248917 0.87 ENSDART00000112170
un-named hu7912
chr13_+_35746440 0.87 ENSDART00000187859
G protein-coupled receptor 75
chr16_-_43025885 0.87 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr23_-_24582606 0.86 ENSDART00000129910
transmembrane protein 240a
chr5_+_57641554 0.86 ENSDART00000171309
ENSDART00000157992
ENSDART00000164742
crystallin, alpha B, b
chr5_-_55395964 0.86 ENSDART00000145791
prune homolog 2 (Drosophila)
chr11_+_25101220 0.86 ENSDART00000183700
ndrg family member 3a
chr9_+_23900703 0.85 ENSDART00000127859
tripartite motif containing 63b
chr25_+_34984333 0.85 ENSDART00000154760
coiled-coil domain containing 136b
chr7_-_39203799 0.85 ENSDART00000173727
cholinergic receptor, muscarinic 4a
chr16_+_21738194 0.85 ENSDART00000163688
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr21_+_11684830 0.85 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr16_-_24518027 0.85 ENSDART00000134120
ENSDART00000143761
cell adhesion molecule 4
chr3_+_36862190 0.85 ENSDART00000149659
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr23_-_1557195 0.84 ENSDART00000136436
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr19_-_9472893 0.84 ENSDART00000045565
ENSDART00000137505
vesicle-associated membrane protein 1
chr16_+_28596555 0.84 ENSDART00000046209
ENSDART00000141708
acyl-CoA binding domain containing 7
chr21_+_11685009 0.83 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr13_-_31452516 0.83 ENSDART00000193268
reticulon 1a
chr23_+_4299887 0.82 ENSDART00000132604
l(3)mbt-like 1a (Drosophila)
chr22_-_17586064 0.82 ENSDART00000060786
ENSDART00000188303
ENSDART00000181212
ENSDART00000181951
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr16_+_5196226 0.82 ENSDART00000189704
SOGA family member 3a
chr16_-_18652646 0.81 ENSDART00000131438
formin homology 2 domain containing 3b
chr23_+_40460333 0.81 ENSDART00000184658
SOGA family member 3b
chr4_-_1360495 0.81 ENSDART00000164623
pleiotrophin
chr2_+_31833997 0.81 ENSDART00000066788
ependymin related 1
chr8_+_48603398 0.81 ENSDART00000074900
zgc:195023
chr21_-_23746916 0.81 ENSDART00000017229
neural cell adhesion molecule 1a
chr6_+_27146671 0.81 ENSDART00000156792
kinesin family member 1Aa
chr3_-_28258462 0.81 ENSDART00000191573
RNA binding fox-1 homolog 1
chr4_-_9586713 0.80 ENSDART00000145613
SH3 and multiple ankyrin repeat domains 3b
chr23_+_37323962 0.80 ENSDART00000102881
family with sequence similarity 43, member B
chr16_-_28856112 0.78 ENSDART00000078543
synaptotagmin XIb
chr11_-_11625630 0.78 ENSDART00000161821
ENSDART00000193152
si:dkey-28e7.3
chr9_+_35901554 0.78 ENSDART00000005086
ATPase Na+/K+ transporting subunit alpha 1b
chr5_-_55395384 0.78 ENSDART00000147298
ENSDART00000082577
prune homolog 2 (Drosophila)
chr19_+_37925616 0.77 ENSDART00000148348
neurexophilin 1
chr3_-_46817499 0.77 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr10_+_10636237 0.76 ENSDART00000136853
family with sequence similarity 163, member B
chr6_-_40006809 0.76 ENSDART00000085666
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr1_+_44491077 0.76 ENSDART00000073736
reticulon 4 receptor-like 2 a
chr14_+_17197132 0.76 ENSDART00000054598
reticulon 4 receptor-like 2b
chr14_+_25816874 0.76 ENSDART00000005499
glycine receptor, alpha 1
chr10_+_25222367 0.76 ENSDART00000042767
glutamate receptor, metabotropic 5a
chr7_-_22132265 0.76 ENSDART00000125284
ENSDART00000112978
neuroligin 2a
chr25_+_14017609 0.76 ENSDART00000129105
ENSDART00000125733
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr8_+_52503340 0.75 ENSDART00000168838
si:ch1073-392o20.1
chr7_+_29952719 0.75 ENSDART00000173737
alpha-tropomyosin
chr24_-_11127493 0.75 ENSDART00000144066
myosin VIIA and Rab interacting protein
chr2_-_34555945 0.75 ENSDART00000056671
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr5_-_31928913 0.75 ENSDART00000142919
slingshot protein phosphatase 1b
chr5_-_67911111 0.75 ENSDART00000051833
GS homeobox 1
chr17_-_26911852 0.75 ENSDART00000045842
regulator of calcineurin 3
chr13_-_36911118 0.74 ENSDART00000048739
tripartite motif containing 9
chr9_+_41612642 0.73 ENSDART00000138473
SPEG complex locus b
chr6_-_26080384 0.73 ENSDART00000157181
ENSDART00000154568
heparan sulfate 2-O-sulfotransferase 1b
chr10_-_34772211 0.73 ENSDART00000145450
ENSDART00000134307
doublecortin-like kinase 1a
chr5_-_31904562 0.73 ENSDART00000140640
coronin, actin binding protein, 1Cb
chr3_+_17806213 0.72 ENSDART00000055890
zinc finger protein 385C
chr20_+_31206346 0.72 ENSDART00000153388
otoferlin a
chr18_-_42395161 0.72 ENSDART00000098641
contactin 5
chr12_-_11570 0.71 ENSDART00000186179
shisa family member 6
chr9_+_40939336 0.71 ENSDART00000100386
myostatin b
chr24_-_34335265 0.71 ENSDART00000128690
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_625875 0.71 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr9_-_31278048 0.71 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr20_-_34868814 0.70 ENSDART00000153049
stathmin-like 4
chr19_+_1510971 0.70 ENSDART00000157721
solute carrier family 45 member 4
chr18_+_17660402 0.70 ENSDART00000143475
copine II
chr21_+_13182149 0.70 ENSDART00000140267
spectrin alpha, non-erythrocytic 1
chr6_-_32703317 0.69 ENSDART00000064833
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr17_+_23938283 0.69 ENSDART00000184391
si:ch211-189k9.2
chr7_+_38717624 0.69 ENSDART00000132522
synaptotagmin XIII
chr10_-_26163989 0.69 ENSDART00000136472
tripartite motif containing 3b
chr14_-_33936524 0.68 ENSDART00000112438
si:ch73-335m24.5
chr18_-_42172101 0.68 ENSDART00000124211
contactin 5
chr23_-_7799184 0.68 ENSDART00000190946
ENSDART00000165427
myelin transcription factor 1b
chr3_-_61099004 0.68 ENSDART00000112043
calcium channel, voltage-dependent, gamma subunit 4b
chr9_-_18877597 0.68 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr18_-_46208581 0.67 ENSDART00000141278
si:ch211-14c7.2
chr13_+_40034176 0.67 ENSDART00000189797
golgin A7 family, member Bb
chr3_+_15550522 0.67 ENSDART00000136912
ENSDART00000176218
si:dkey-93n13.3
chr1_+_41690402 0.67 ENSDART00000177298
F-box protein 41
chr25_+_7229046 0.67 ENSDART00000149965
ENSDART00000041820
leucine rich repeat and Ig domain containing 1a
chr19_+_10396042 0.67 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr24_-_17047918 0.66 ENSDART00000020204
methionine sulfoxide reductase B2
chr22_-_354592 0.66 ENSDART00000155769
transmembrane protein 240b
chr5_-_35252761 0.66 ENSDART00000051278
transportin 1
chr2_+_15776649 0.66 ENSDART00000156535
vav 3 guanine nucleotide exchange factor b
chr11_-_18800299 0.66 ENSDART00000156276
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr2_+_6181383 0.66 ENSDART00000153307
si:ch73-344o19.1
chr7_+_29955368 0.66 ENSDART00000173686
alpha-tropomyosin
chr20_+_88168 0.66 ENSDART00000149283
zgc:112001
chr9_+_17984358 0.66 ENSDART00000192399
A kinase (PRKA) anchor protein 11
chr11_-_11625369 0.65 ENSDART00000112328
si:dkey-28e7.3
chr16_+_41873708 0.65 ENSDART00000084631
ENSDART00000084639
ENSDART00000058611
sodium channel, voltage-gated, type I, beta a
chr24_-_29997145 0.65 ENSDART00000135094
palmdelphin b
chr21_-_21373242 0.65 ENSDART00000079629
protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr13_+_28702104 0.65 ENSDART00000135481
si:ch211-67n3.9
chr13_-_36184701 0.65 ENSDART00000146522
mitogen-activated protein kinase kinase kinase 9
chr22_+_18389271 0.65 ENSDART00000088270
YjeF N-terminal domain containing 3
chr5_+_22098591 0.64 ENSDART00000143676
zinc finger CCCH-type containing 12B
chr11_-_18799827 0.64 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr7_-_49594995 0.64 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr7_-_67894046 0.64 ENSDART00000168964
si:ch73-315f9.2
chr19_-_31707892 0.64 ENSDART00000088427
RHO family interacting cell polarization regulator 2
chr16_+_32559821 0.64 ENSDART00000093250
POU class 3 homeobox 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of pax2a+pax5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.6 1.8 GO:0097623 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.6 1.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 1.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 1.1 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.4 1.4 GO:0021557 oculomotor nerve development(GO:0021557)
0.3 1.0 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.3 1.2 GO:0060074 synapse maturation(GO:0060074)
0.3 3.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.3 0.9 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3 1.7 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.3 1.4 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.3 1.6 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.3 0.8 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.3 0.8 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.2 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2 1.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 0.6 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 1.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 1.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 0.5 GO:0042908 xenobiotic transport(GO:0042908)
0.2 0.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.7 GO:0030091 protein repair(GO:0030091)
0.2 0.7 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.2 0.2 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.2 0.6 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.5 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 0.5 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.2 1.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.6 GO:1901862 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.2 1.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.6 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.4 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.5 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.9 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 2.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.8 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.9 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 1.4 GO:0050936 xanthophore differentiation(GO:0050936)
0.1 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 2.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 2.2 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.5 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.7 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.6 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.5 GO:0055016 hypochord development(GO:0055016)
0.1 1.3 GO:0034333 adherens junction assembly(GO:0034333)
0.1 0.4 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 1.3 GO:0035108 limb morphogenesis(GO:0035108)
0.1 1.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 2.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.5 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 2.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.4 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.8 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.2 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.5 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.1 0.4 GO:0035989 tendon development(GO:0035989)
0.1 0.4 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 2.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.1 0.1 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.1 0.4 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 1.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.3 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.8 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 1.1 GO:0048899 anterior lateral line development(GO:0048899)
0.1 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.9 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.5 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.6 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.6 GO:0046661 male sex differentiation(GO:0046661)
0.1 0.2 GO:0010657 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.5 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 0.2 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.1 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.2 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 0.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.4 GO:0032196 transposition(GO:0032196)
0.1 1.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.6 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 2.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.2 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 2.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.6 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0031034 myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 2.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.4 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.0 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.7 GO:0033135 regulation of peptidyl-serine phosphorylation(GO:0033135)
0.0 0.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.7 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.8 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 1.7 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 1.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.2 GO:0044241 lipid digestion(GO:0044241)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.4 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 4.7 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0002093 auditory receptor cell morphogenesis(GO:0002093)
0.0 3.0 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0001964 startle response(GO:0001964)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.2 GO:0098926 postsynaptic signal transduction(GO:0098926)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.6 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.4 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.9 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.7 GO:0003323 glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.0 0.8 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.5 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.8 GO:0031103 axon regeneration(GO:0031103)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 2.4 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 2.6 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.6 GO:0038084 vascular endothelial growth factor signaling pathway(GO:0038084)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.5 GO:0039022 pronephric duct development(GO:0039022)
0.0 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0051125 regulation of actin nucleation(GO:0051125)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 2.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0070302 regulation of stress-activated MAPK cascade(GO:0032872) regulation of stress-activated protein kinase signaling cascade(GO:0070302)
0.0 0.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 1.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.0 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.3 GO:0033338 medial fin development(GO:0033338)
0.0 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.7 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.1 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0030901 midbrain development(GO:0030901)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.4 GO:0036269 swimming behavior(GO:0036269)
0.0 0.8 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 1.3 GO:0070509 calcium ion import(GO:0070509)
0.0 0.3 GO:0046058 cAMP metabolic process(GO:0046058)
0.0 0.1 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 3.4 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 0.4 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 2.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.0 GO:0033333 fin development(GO:0033333)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.8 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.3 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.2 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0033268 node of Ranvier(GO:0033268)
0.3 3.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.3 1.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.2 0.8 GO:0016460 myosin II complex(GO:0016460)
0.2 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 2.1 GO:0005922 connexon complex(GO:0005922)
0.2 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.6 GO:0060171 stereocilium membrane(GO:0060171)
0.1 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.8 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.9 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 2.0 GO:0043209 myelin sheath(GO:0043209)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.4 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.1 2.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 1.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.3 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 7.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.3 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.1 2.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 1.6 GO:0030426 growth cone(GO:0030426)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 3.5 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 4.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 12.5 GO:0043005 neuron projection(GO:0043005)
0.0 0.5 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031672 A band(GO:0031672)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.3 GO:0005884 actin filament(GO:0005884)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.9 GO:0005769 early endosome(GO:0005769)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.5 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1903136 cuprous ion binding(GO:1903136)
0.5 2.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 0.9 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.2 1.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 0.8 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.2 0.5 GO:0031704 apelin receptor binding(GO:0031704)
0.2 3.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.2 0.8 GO:2001070 starch binding(GO:2001070)
0.2 0.7 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.2 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 2.1 GO:0005243 gap junction channel activity(GO:0005243)
0.2 0.5 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.1 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.1 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.8 GO:0048156 tau protein binding(GO:0048156)
0.1 0.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 0.6 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.8 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.5 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 1.2 GO:0008443 phosphofructokinase activity(GO:0008443)
0.1 1.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 2.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.3 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.6 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 1.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.8 GO:0022829 wide pore channel activity(GO:0022829)
0.1 1.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.2 GO:0019894 kinesin binding(GO:0019894)
0.1 1.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 1.0 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 2.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 0.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.5 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.6 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.1 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.4 GO:0017022 myosin binding(GO:0017022)
0.1 0.2 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 1.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.8 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 2.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 2.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 6.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 5.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 5.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.0 0.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 3.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane