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PRJNA207719: Tissue specific transcriptome profiling

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Results for pou3f1

Z-value: 0.97

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Transcription factors associated with pou3f1

Gene Symbol Gene ID Gene Info
pou3f1
ENSDARG00000009823 POU class 3 homeobox 1
pou3f1
ENSDARG00000112302 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou3f1dr11_v1_chr16_+_33593116_335931160.951.2e-02Click!

Activity profile of pou3f1 motif

Sorted Z-values of pou3f1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_30563115 1.39 ENSDART00000028566
si:ch211-200p22.4
si:ch211-200p22.4
chr22_+_20195280 1.29 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
si:dkey-110c1.7
chr23_+_28731379 0.99 ENSDART00000047378
cort
cortistatin
chr18_-_36135799 0.97 ENSDART00000059344
b3gat1a
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr23_+_44307996 0.97 ENSDART00000042430
dlg4b
discs, large homolog 4b (Drosophila)
chr19_-_28367413 0.90 ENSDART00000079092
si:dkey-261i16.5
si:dkey-261i16.5
chr19_-_30562648 0.90 ENSDART00000171006
hpcal4
hippocalcin like 4
chr3_-_5964557 0.86 ENSDART00000184738
BX284638.1

chr21_-_27185915 0.86 ENSDART00000135052
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr9_-_18877597 0.85 ENSDART00000099446
kctd4
potassium channel tetramerization domain containing 4
chr23_+_36771593 0.85 ENSDART00000078240
march9
membrane-associated ring finger (C3HC4) 9
chr16_-_12173399 0.84 ENSDART00000142574
clstn3
calsyntenin 3
chr7_+_40228422 0.83 ENSDART00000052222
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr6_-_13187168 0.81 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
adam23a
ADAM metallopeptidase domain 23a
chr16_-_12173554 0.80 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr12_+_48480632 0.76 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr16_-_43971258 0.75 ENSDART00000141941
zfpm2a
zinc finger protein, FOG family member 2a
chr7_-_38633867 0.73 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr22_+_5106751 0.73 ENSDART00000138967
atcaya
ataxia, cerebellar, Cayman type a
chr21_+_41743493 0.72 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr10_+_22003750 0.72 ENSDART00000109420
kcnip1b
Kv channel interacting protein 1 b
chr2_-_34555945 0.72 ENSDART00000056671
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr3_-_6519691 0.71 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
GGA3 (1 of many)
si:ch73-157i16.3
chr17_-_15528597 0.69 ENSDART00000150232
fyna
FYN proto-oncogene, Src family tyrosine kinase a
chr3_+_33345348 0.69 ENSDART00000059262
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr16_+_45746549 0.66 ENSDART00000190403
paqr6
progestin and adipoQ receptor family member VI
chr23_+_28582865 0.63 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr13_+_33117528 0.63 ENSDART00000085719
si:ch211-10a23.2
si:ch211-10a23.2
chr6_-_13188667 0.62 ENSDART00000191654
adam23a
ADAM metallopeptidase domain 23a
chr5_-_24000211 0.62 ENSDART00000188865
map7d2a
MAP7 domain containing 2a
chr5_-_16996482 0.60 ENSDART00000144501
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr6_+_4539953 0.60 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr22_-_38516922 0.58 ENSDART00000151257
ENSDART00000151785
klc4
kinesin light chain 4
chr2_+_24203229 0.57 ENSDART00000138088
map4l
microtubule associated protein 4 like
chr16_+_43152727 0.56 ENSDART00000125590
ENSDART00000154493
adam22
ADAM metallopeptidase domain 22
chr4_-_8903240 0.55 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr8_+_28593707 0.55 ENSDART00000097213
tcf15
transcription factor 15
chr18_-_12957451 0.54 ENSDART00000140403
srgap1a
SLIT-ROBO Rho GTPase activating protein 1a
chr22_-_7400471 0.54 ENSDART00000161215
si:dkey-57c15.1
si:dkey-57c15.1
chr16_+_39159752 0.53 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr14_-_40389699 0.53 ENSDART00000181581
ENSDART00000173398
pcdh19
protocadherin 19
chr20_+_27298783 0.51 ENSDART00000013861
ppp4r4
protein phosphatase 4, regulatory subunit 4
chr6_-_13308813 0.51 ENSDART00000065372
kcnj3b
potassium inwardly-rectifying channel, subfamily J, member 3b
chr22_-_11954861 0.50 ENSDART00000131611
si:dkeyp-4h4.1
si:dkeyp-4h4.1
chr12_+_46960579 0.49 ENSDART00000149032
oat
ornithine aminotransferase
chr2_+_2563192 0.48 ENSDART00000055713
CABZ01033000.1

chr20_-_39188476 0.47 ENSDART00000152858
rcan2
regulator of calcineurin 2
chr10_+_33895315 0.46 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr22_+_14051894 0.46 ENSDART00000142548
aox6
aldehyde oxidase 6
chr4_+_31259 0.45 ENSDART00000166826
phtf2
putative homeodomain transcription factor 2
chr5_+_30624183 0.45 ENSDART00000141444
abcg4a
ATP-binding cassette, sub-family G (WHITE), member 4a
chr1_+_46194333 0.45 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr7_-_24699985 0.45 ENSDART00000052802
calb2b
calbindin 2b
chr22_+_413349 0.44 ENSDART00000082453
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr8_-_15398760 0.44 ENSDART00000162011
agbl4
ATP/GTP binding protein-like 4
chr20_+_18225329 0.44 ENSDART00000144172
kctd1
potassium channel tetramerization domain containing 1
chr17_+_15882533 0.43 ENSDART00000164124
gabrr2a
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr6_+_41096058 0.42 ENSDART00000028373
fkbp5
FK506 binding protein 5
chr25_-_25736958 0.41 ENSDART00000166308
cib2
calcium and integrin binding family member 2
chr13_+_28705143 0.40 ENSDART00000183338
ldb1a
LIM domain binding 1a
chr5_-_46896541 0.40 ENSDART00000133240
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr19_-_31707892 0.40 ENSDART00000088427
ripor2
RHO family interacting cell polarization regulator 2
chr18_+_7286788 0.39 ENSDART00000022998
ANO2 (1 of many)
si:ch73-86n2.1
chr17_+_33719415 0.38 ENSDART00000132294
fut8a
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr18_+_38749547 0.38 ENSDART00000143735
si:ch211-215d8.2
si:ch211-215d8.2
chr6_+_45692026 0.37 ENSDART00000164759
cntn4
contactin 4
chr1_+_7679328 0.37 ENSDART00000163488
ENSDART00000190070
en1b
engrailed homeobox 1b
chr5_-_25406807 0.36 ENSDART00000089748
rorb
RAR-related orphan receptor B
chr9_-_31915423 0.35 ENSDART00000060051
fgf14
fibroblast growth factor 14
chr19_+_2726819 0.34 ENSDART00000187122
ENSDART00000112414
rapgef5a
Rap guanine nucleotide exchange factor (GEF) 5a
chr22_+_18786797 0.34 ENSDART00000141864
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr22_+_18389271 0.34 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr15_+_39096736 0.33 ENSDART00000129511
ENSDART00000014877
robo2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr21_-_30254185 0.33 ENSDART00000101054
dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr21_-_25573064 0.33 ENSDART00000134310
CR388166.1

chr1_+_1599979 0.33 ENSDART00000097626
urp2
urotensin II-related peptide
chr7_+_61050329 0.31 ENSDART00000115355
nwd2
NACHT and WD repeat domain containing 2
chr9_-_18735256 0.31 ENSDART00000143165
tsc22d1
TSC22 domain family, member 1
chr17_-_37052622 0.31 ENSDART00000186408
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr13_-_33822550 0.31 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr19_-_19556778 0.30 ENSDART00000164060
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr20_-_45060241 0.30 ENSDART00000185227
klhl29
kelch-like family member 29
chr4_+_20255160 0.30 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr25_-_26673570 0.29 ENSDART00000154917
ciartb
circadian associated repressor of transcription b
chr24_-_40009446 0.29 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr17_+_20500229 0.29 ENSDART00000088490
neurl1ab
neuralized E3 ubiquitin protein ligase 1Ab
chr15_+_42933236 0.28 ENSDART00000167763
slc8a2b
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr16_-_26435431 0.28 ENSDART00000187526
megf8
multiple EGF-like-domains 8
chr11_-_35575791 0.28 ENSDART00000031441
ENSDART00000188513
ENSDART00000183609
sema3fb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr15_-_30815826 0.27 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr1_+_31725154 0.27 ENSDART00000112333
ENSDART00000189801
cnnm2b
cyclin and CBS domain divalent metal cation transport mediator 2b
chr21_+_5888641 0.27 ENSDART00000091331
prodha
proline dehydrogenase (oxidase) 1a
chr9_-_21507083 0.27 ENSDART00000137922
aff3
AF4/FMR2 family, member 3
chr13_+_29773153 0.27 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
pax2a
paired box 2a
chr6_-_19381993 0.27 ENSDART00000164114
grb2a
growth factor receptor-bound protein 2a
chr18_+_660578 0.27 ENSDART00000161203
CELF6
si:dkey-205h23.2
chr13_+_42406883 0.27 ENSDART00000084354
cpeb3
cytoplasmic polyadenylation element binding protein 3
chr4_-_9579299 0.26 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr9_+_34331368 0.26 ENSDART00000147913
pou2f1b
POU class 2 homeobox 1b
chr7_+_10701938 0.26 ENSDART00000158162
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr25_-_15045338 0.26 ENSDART00000161165
ENSDART00000165774
ENSDART00000172538
pax6a
paired box 6a
chr24_+_41931585 0.25 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr14_+_23874062 0.24 ENSDART00000172149
sh3rf2
SH3 domain containing ring finger 2
chr13_-_24877577 0.24 ENSDART00000182705
kat6b
K(lysine) acetyltransferase 6B
chr19_+_41464870 0.24 ENSDART00000102778
dlx6a
distal-less homeobox 6a
chr5_-_26323137 0.24 ENSDART00000133823
arvcfb
ARVCF, delta catenin family member b
chr15_-_18361475 0.24 ENSDART00000155866
zbtb16b
zinc finger and BTB domain containing 16b
chr7_+_31074636 0.24 ENSDART00000173805
tjp1a
tight junction protein 1a
chr9_-_25444091 0.24 ENSDART00000002428
acvr2aa
activin A receptor type 2Aa
chr4_+_12292274 0.24 ENSDART00000061070
ENSDART00000150786
mkrn1
makorin, ring finger protein, 1
chr13_+_28618086 0.23 ENSDART00000087001
cnnm2a
cyclin and CBS domain divalent metal cation transport mediator 2a
chr1_+_8984068 0.23 ENSDART00000122568
tlr2
toll-like receptor 2
chr14_-_34700633 0.23 ENSDART00000150358
ablim3
actin binding LIM protein family, member 3
chr7_+_13824150 0.23 ENSDART00000035067
abhd2a
abhydrolase domain containing 2a
chr22_-_10397600 0.23 ENSDART00000181964
ENSDART00000142886
nisch
nischarin
chr13_+_29778610 0.23 ENSDART00000132004
pax2a
paired box 2a
chr23_+_2825940 0.23 ENSDART00000135781
plcg1
phospholipase C, gamma 1
chr11_+_25634041 0.22 ENSDART00000033657
grm6b
glutamate receptor, metabotropic 6b
chr5_+_9147497 0.22 ENSDART00000003273
rchy1
ring finger and CHY zinc finger domain containing 1
chr10_-_5821584 0.22 ENSDART00000166388
il6st
interleukin 6 signal transducer
chr16_+_25074029 0.22 ENSDART00000155465
si:dkeyp-84f3.9
si:dkeyp-84f3.9
chr7_+_25920792 0.21 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr8_-_43574935 0.21 ENSDART00000051139
ncor2
nuclear receptor corepressor 2
chr9_-_30502010 0.21 ENSDART00000149483
si:dkey-229b18.3
si:dkey-229b18.3
chr1_-_20593778 0.21 ENSDART00000124770
ugt8
UDP glycosyltransferase 8
chr11_-_41130239 0.20 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr3_+_26223376 0.20 ENSDART00000128284
nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr20_+_20751425 0.20 ENSDART00000177048
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr7_-_26497947 0.20 ENSDART00000058910
sox19b
SRY (sex determining region Y)-box 19b
chr12_+_16087077 0.20 ENSDART00000141898
znf281b
zinc finger protein 281b
chr21_-_32467099 0.19 ENSDART00000186354
zgc:123105
zgc:123105
chr17_-_25831569 0.19 ENSDART00000148743
hhat
hedgehog acyltransferase
chr6_-_54111928 0.19 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a
chr1_-_24918686 0.19 ENSDART00000148076
fbxw7
F-box and WD repeat domain containing 7
chr18_+_22606259 0.19 ENSDART00000128965
bcar1
breast cancer anti-estrogen resistance 1
chr14_-_48939560 0.19 ENSDART00000021736
scocb
short coiled-coil protein b
chr2_-_39036604 0.18 ENSDART00000129963
rbp1
retinol binding protein 1b, cellular
chr10_+_33744098 0.18 ENSDART00000147775
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr9_+_12444494 0.18 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr10_+_44940693 0.18 ENSDART00000157515
cnnm4a
cyclin and CBS domain divalent metal cation transport mediator 4a
chr22_-_32392252 0.18 ENSDART00000148681
ENSDART00000137945
pcbp4
poly(rC) binding protein 4
chr23_+_20518504 0.17 ENSDART00000114246
adnpb
activity-dependent neuroprotector homeobox b
chr7_+_20965880 0.17 ENSDART00000062003
efnb3b
ephrin-B3b
chr17_-_30473374 0.17 ENSDART00000155021
si:ch211-175f11.5
si:ch211-175f11.5
chr1_+_54013457 0.17 ENSDART00000012104
ENSDART00000126339
dla
deltaA
chr1_-_31350148 0.17 ENSDART00000085370
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr19_-_32042105 0.17 ENSDART00000088358
znf704
zinc finger protein 704
chr12_+_28986308 0.17 ENSDART00000153178
si:rp71-1c10.8
si:rp71-1c10.8
chr25_+_25737386 0.17 ENSDART00000108476
lrrc61
leucine rich repeat containing 61
chr19_-_26770083 0.17 ENSDART00000193811
ENSDART00000174455
prrc2a
proline-rich coiled-coil 2A
chr7_-_46777876 0.17 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr7_-_4036184 0.16 ENSDART00000019949
ndrg2
NDRG family member 2
chr17_-_4245311 0.16 ENSDART00000055379
gdf3
growth differentiation factor 3
chr19_-_26769867 0.16 ENSDART00000043776
ENSDART00000159489
ENSDART00000138675
prrc2a
proline-rich coiled-coil 2A
chr2_-_56131312 0.16 ENSDART00000097755
jund
JunD proto-oncogene, AP-1 transcription factor subunit
chr23_-_36934944 0.16 ENSDART00000109976
ENSDART00000162179
acap3a
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr10_-_27196093 0.16 ENSDART00000185282
auts2a
autism susceptibility candidate 2a
chr4_-_16406737 0.15 ENSDART00000013085
dcn
decorin
chr1_-_17587552 0.15 ENSDART00000039917
acsl1a
acyl-CoA synthetase long chain family member 1a
chr25_+_27923846 0.15 ENSDART00000047007
slc13a1
solute carrier family 13 member 1
chr8_+_8238727 0.14 ENSDART00000144838
plxnb3
plexin B3
chr11_+_21586335 0.14 ENSDART00000091182
FAM72B
zgc:101564
chr16_-_21620947 0.14 ENSDART00000115011
ENSDART00000183125
ENSDART00000188856
ENSDART00000189460
ddr1
discoidin domain receptor tyrosine kinase 1
chr14_+_37545639 0.14 ENSDART00000173192
pcdh1b
protocadherin 1b
chr5_+_63785339 0.14 ENSDART00000050871
rgs3b
regulator of G protein signaling 3b
chr10_+_42521943 0.14 ENSDART00000010420
ENSDART00000075303
actr1
ARP1 actin related protein 1, centractin
chr3_+_30190419 0.14 ENSDART00000157320
akt1s1
AKT1 substrate 1 (proline-rich)
chr3_-_21118969 0.13 ENSDART00000129016
maza
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr6_+_18418651 0.13 ENSDART00000171097
ENSDART00000167798
rab11fip4b
RAB11 family interacting protein 4 (class II) b
chr20_-_2361226 0.13 ENSDART00000172130
EPB41L2
si:ch73-18b11.1
chr24_-_37484123 0.13 ENSDART00000111623
cluap1
clusterin associated protein 1
chr2_-_7185460 0.13 ENSDART00000092078
rc3h1b
ring finger and CCCH-type domains 1b
chr1_+_27825980 0.13 ENSDART00000160524
pspc1
paraspeckle component 1
chr15_-_1622468 0.12 ENSDART00000149008
ENSDART00000034456
kpna4
karyopherin alpha 4 (importin alpha 3)
chr19_-_6239248 0.12 ENSDART00000014127
pou2f2a
POU class 2 homeobox 2a
chr6_+_23935045 0.12 ENSDART00000162993
gadd45ab
growth arrest and DNA-damage-inducible, alpha, b
chr14_-_28001986 0.12 ENSDART00000054115
tsc22d3
TSC22 domain family, member 3
chr1_+_32051581 0.12 ENSDART00000146602
sts
steroid sulfatase (microsomal), isozyme S
chr2_-_37684641 0.11 ENSDART00000012191
hiat1a
hippocampus abundant transcript 1a
chr2_-_3616363 0.11 ENSDART00000144699
pter
phosphotriesterase related
chr7_+_69470442 0.11 ENSDART00000189593
gabarapb
GABA(A) receptor-associated protein b
chr8_+_31777633 0.11 ENSDART00000142519
oxct1a
3-oxoacid CoA transferase 1a
chr17_+_26352372 0.11 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr23_-_893547 0.11 ENSDART00000136805
rbm10
RNA binding motif protein 10
chr16_+_49089123 0.11 ENSDART00000187494
plcl2
phospholipase C like 2
chr25_+_5604512 0.11 ENSDART00000042781
plxnb2b
plexin b2b
chr4_+_12013043 0.10 ENSDART00000130692
cry1aa
cryptochrome circadian clock 1aa
chr17_-_4245902 0.10 ENSDART00000151851
gdf3
growth differentiation factor 3
chr21_+_26390549 0.10 ENSDART00000185643
tmsb
thymosin, beta
chr10_+_39304422 0.10 ENSDART00000019267
kcnj1b
potassium inwardly-rectifying channel, subfamily J, member 1b
chr10_-_26225548 0.10 ENSDART00000132019
ENSDART00000079194
arfip2b
ADP-ribosylation factor interacting protein 2b
chr5_+_69733096 0.10 ENSDART00000169013
arl6ip4
ADP-ribosylation factor-like 6 interacting protein 4
chr16_+_34046733 0.10 ENSDART00000058424
fam46ba
family with sequence similarity 46, member Ba
chr21_-_35853245 0.10 ENSDART00000172245
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr22_-_18491813 0.10 ENSDART00000105419
si:ch211-212d10.2
si:ch211-212d10.2
chr1_-_40411944 0.10 ENSDART00000144135
maml3
mastermind-like transcriptional coactivator 3
chr23_-_26725637 0.10 ENSDART00000157844
hspg2
heparan sulfate proteoglycan 2
chr21_+_8427059 0.10 ENSDART00000143151
dennd1a
DENN/MADD domain containing 1A
chr7_+_60396957 0.09 ENSDART00000121545
brms1
breast cancer metastasis suppressor 1
chr2_-_24317240 0.09 ENSDART00000078975
trnau1apb
tRNA selenocysteine 1 associated protein 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of pou3f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.2 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.0 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.1 0.5 GO:0060074 synapse maturation(GO:0060074)
0.1 0.4 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.4 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.9 GO:0042044 fluid transport(GO:0042044)
0.1 0.7 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.2 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.5 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.2 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.2 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.3 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.3 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.2 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.1 GO:0021742 abducens nucleus development(GO:0021742)
0.0 0.2 GO:0055016 hypochord development(GO:0055016)
0.0 0.4 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.6 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.3 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 1.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0030141 secretory granule(GO:0030141)
0.0 1.1 GO:0042383 sarcolemma(GO:0042383)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.7 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity