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PRJNA207719: Tissue specific transcriptome profiling

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Results for pou4f3_pou4f1+pou4f4

Z-value: 3.28

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Transcription factors associated with pou4f3_pou4f1+pou4f4

Gene Symbol Gene ID Gene Info
pou4f3
ENSDARG00000006206 POU class 4 homeobox 3
pou4f1
ENSDARG00000005559 POU class 4 homeobox 1
pou4f4
ENSDARG00000044375 zgc
pou4f4
ENSDARG00000111929 zgc

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou4f1dr11_v1_chr6_+_4539953_45399530.975.0e-03Click!
zgc:158291dr11_v1_chr21_+_38312549_383125490.903.7e-02Click!
pou4f3dr11_v1_chr9_+_54290896_542908960.751.4e-01Click!

Activity profile of pou4f3_pou4f1+pou4f4 motif

Sorted Z-values of pou4f3_pou4f1+pou4f4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_21688176 4.74 ENSDART00000063825
sprn
shadow of prion protein
chr23_-_27345425 4.58 ENSDART00000022042
ENSDART00000191870
scn8aa
sodium channel, voltage gated, type VIII, alpha subunit a
chr20_+_9355912 4.13 ENSDART00000142337
si:dkey-174m14.3
si:dkey-174m14.3
chr5_+_58372164 3.91 ENSDART00000057910
nrgna
neurogranin (protein kinase C substrate, RC3) a
chr24_-_3419998 3.79 ENSDART00000066839
slc35g2b
solute carrier family 35, member G2b
chr2_+_50608099 3.57 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr24_+_14713776 3.48 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr23_-_24195723 3.42 ENSDART00000145489
ano11
anoctamin 11
chr21_-_13123176 3.32 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr23_-_24195519 3.30 ENSDART00000112370
ENSDART00000180377
ano11
anoctamin 11
chr16_+_10318893 3.27 ENSDART00000055380
tubb5
tubulin, beta 5
chr11_+_6819050 3.01 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr4_+_12111154 3.01 ENSDART00000036779
tmem178b
transmembrane protein 178B
chr23_-_29376859 2.95 ENSDART00000146411
sst6
somatostatin 6
chr13_-_43599898 2.75 ENSDART00000084416
ENSDART00000145705
ablim1a
actin binding LIM protein 1a
chr16_+_14029283 2.74 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr16_-_12953739 2.70 ENSDART00000103894
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr11_+_37137196 2.62 ENSDART00000172950
wnk2
WNK lysine deficient protein kinase 2
chr2_+_39108339 2.53 ENSDART00000085675
clstn2
calsyntenin 2
chr9_-_6661657 2.52 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
pou3f3a
POU class 3 homeobox 3a
chr6_-_39489190 2.42 ENSDART00000151299
scn8ab
sodium channel, voltage gated, type VIII, alpha subunit b
chr2_+_25929619 2.42 ENSDART00000137746
slc7a14a
solute carrier family 7, member 14a
chr20_-_34801181 2.34 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr9_-_18735256 2.29 ENSDART00000143165
tsc22d1
TSC22 domain family, member 1
chr25_-_13614863 2.19 ENSDART00000121859
fa2h
fatty acid 2-hydroxylase
chr14_-_18672561 2.18 ENSDART00000166730
ENSDART00000006998
slitrk4
SLIT and NTRK-like family, member 4
chr5_+_4054704 2.18 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr4_+_9669717 2.16 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr5_-_23429228 2.07 ENSDART00000049291
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr17_-_51893123 2.01 ENSDART00000103350
ENSDART00000017329
numb
numb homolog (Drosophila)
chr20_-_31808779 1.97 ENSDART00000133788
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr7_-_28148310 1.96 ENSDART00000044208
lmo1
LIM domain only 1
chr5_-_31689796 1.96 ENSDART00000184319
ENSDART00000190229
ENSDART00000186294
ENSDART00000170313
ENSDART00000147065
ENSDART00000134427
ENSDART00000098172
sh3glb2b
SH3-domain GRB2-like endophilin B2b
chr17_+_33999630 1.93 ENSDART00000167085
ENSDART00000155030
ENSDART00000168522
ENSDART00000191799
ENSDART00000189684
ENSDART00000153942
ENSDART00000187272
ENSDART00000127692
gphna
gephyrin a
chr20_+_22045089 1.93 ENSDART00000063564
ENSDART00000187013
ENSDART00000161552
ENSDART00000174478
ENSDART00000063568
ENSDART00000152247
nmu
neuromedin U
chr3_+_22578369 1.93 ENSDART00000187695
ENSDART00000182678
ENSDART00000112270
tanc2a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr16_+_10776688 1.87 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr12_-_10705916 1.84 ENSDART00000164038
FO704786.1

chr11_-_38083397 1.78 ENSDART00000086516
ENSDART00000184033
klhdc8a
kelch domain containing 8A
chr1_-_22861348 1.77 ENSDART00000139412
SMIM18
si:dkey-92j12.6
chr19_+_30662529 1.69 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr19_-_10196370 1.69 ENSDART00000091707
dbpa
D site albumin promoter binding protein a
chr11_+_23957440 1.63 ENSDART00000190721
cntn2
contactin 2
chr9_+_7030016 1.60 ENSDART00000148047
ENSDART00000148181
inpp4aa
inositol polyphosphate-4-phosphatase type I Aa
chr5_-_30418636 1.58 ENSDART00000098285
atf5a
activating transcription factor 5a
chr22_-_3564563 1.57 ENSDART00000145114
ptprsa
protein tyrosine phosphatase, receptor type, s, a
chr23_-_27692717 1.57 ENSDART00000053878
ENSDART00000145028
IKZF4
si:dkey-166n8.9
chr22_+_15507218 1.56 ENSDART00000125450
gpc1a
glypican 1a
chr1_+_38758261 1.56 ENSDART00000182756
wdr17
WD repeat domain 17
chr10_+_42423318 1.52 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr1_+_38758445 1.45 ENSDART00000136300
wdr17
WD repeat domain 17
chr22_-_28226948 1.44 ENSDART00000147686
si:dkey-222p3.1
si:dkey-222p3.1
chr1_+_31113951 1.44 ENSDART00000129362
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr12_+_2446837 1.43 ENSDART00000112032
ARHGAP22
si:dkey-191m6.4
chr6_-_16394528 1.43 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr3_-_23407720 1.41 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr20_+_37661547 1.38 ENSDART00000007253
aig1
androgen-induced 1 (H. sapiens)
chr11_+_19060278 1.37 ENSDART00000164294
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr6_-_41229787 1.37 ENSDART00000065013
synpr
synaptoporin
chr9_+_34319333 1.37 ENSDART00000035522
ENSDART00000146480
pou2f1b
POU class 2 homeobox 1b
chr6_-_35446110 1.37 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr1_-_15797663 1.37 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr20_-_44575103 1.36 ENSDART00000192573
ubxn2a
UBX domain protein 2A
chr11_+_23760470 1.35 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
nfasca
neurofascin homolog (chicken) a
chr7_+_73397283 1.35 ENSDART00000174390
CABZ01081780.1

chr20_+_41756996 1.33 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr11_+_25101220 1.33 ENSDART00000183700
ndrg3a
ndrg family member 3a
chr19_+_37620342 1.31 ENSDART00000158960
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr7_-_69298271 1.30 ENSDART00000122935
phlpp2
PH domain and leucine rich repeat protein phosphatase 2
chr20_+_27298783 1.30 ENSDART00000013861
ppp4r4
protein phosphatase 4, regulatory subunit 4
chr5_+_70271799 1.25 ENSDART00000101316
znf618
zinc finger protein 618
chr4_+_6869847 1.25 ENSDART00000036646
dock4b
dedicator of cytokinesis 4b
chr25_-_13614702 1.25 ENSDART00000165510
ENSDART00000190959
fa2h
fatty acid 2-hydroxylase
chr3_-_16055432 1.24 ENSDART00000123621
ENSDART00000023859
atp6v0ca
ATPase H+ transporting V0 subunit ca
chr6_+_45494227 1.24 ENSDART00000159863
cntn4
contactin 4
chr2_+_22702488 1.22 ENSDART00000076647
kif1ab
kinesin family member 1Ab
chr3_-_23406964 1.21 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr15_+_32297441 1.20 ENSDART00000153657
trim3a
tripartite motif containing 3a
chr16_-_49505275 1.19 ENSDART00000160784
satb1b
SATB homeobox 1b
chr17_+_26208630 1.17 ENSDART00000087084
grid1a
glutamate receptor, ionotropic, delta 1a
chr20_+_31076488 1.16 ENSDART00000136255
ENSDART00000008840
otofa
otoferlin a
chr15_-_14552101 1.14 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr17_+_26352372 1.13 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr3_-_28665291 1.10 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr18_+_34362608 1.09 ENSDART00000131478
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr3_-_28048475 1.07 ENSDART00000150888
rbfox1
RNA binding fox-1 homolog 1
chr13_-_39830999 1.02 ENSDART00000115089
zgc:171482
zgc:171482
chr25_+_21833287 1.01 ENSDART00000187606
ckmt1
creatine kinase, mitochondrial 1
chr25_+_24291156 1.00 ENSDART00000083407
b4galnt4a
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr15_+_24704798 1.00 ENSDART00000192470
LRRC75A
si:dkey-151p21.7
chr17_-_20287530 1.00 ENSDART00000078703
ENSDART00000191289
add3b
adducin 3 (gamma) b
chr16_+_1353894 0.99 ENSDART00000148426
celf3b
cugbp, Elav-like family member 3b
chr18_-_47662696 0.99 ENSDART00000184260
CABZ01073963.1

chr1_+_44491077 0.97 ENSDART00000073736
rtn4rl2a
reticulon 4 receptor-like 2 a
chr9_-_23147026 0.96 ENSDART00000167266
lypd6b
LY6/PLAUR domain containing 6B
chr16_+_43401005 0.96 ENSDART00000110994
sqlea
squalene epoxidase a
chr24_-_26622423 0.96 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr20_+_20638034 0.94 ENSDART00000189759
rtn1b
reticulon 1b
chr6_+_21740672 0.94 ENSDART00000193734
lhfpl4a
lipoma HMGIC fusion partner-like 4a
chr6_+_38427570 0.93 ENSDART00000170612
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr17_+_31914877 0.93 ENSDART00000177801
FAM196A (1 of many)
family with sequence similarity 196 member A
chr14_+_34495216 0.92 ENSDART00000147756
wnt8a
wingless-type MMTV integration site family, member 8a
chr8_+_668184 0.91 ENSDART00000183788
rnf165b
ring finger protein 165b
chr20_+_17783404 0.91 ENSDART00000181946
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr13_+_27951688 0.91 ENSDART00000050303
b3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr2_-_9818640 0.90 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr21_-_39177564 0.90 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr19_+_42693855 0.89 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr3_-_61336841 0.89 ENSDART00000155414
tecpr1b
tectonin beta-propeller repeat containing 1b
chr8_+_7975745 0.89 ENSDART00000137920
si:ch211-169p10.1
si:ch211-169p10.1
chr10_+_40214877 0.86 ENSDART00000109689
gramd1ba
GRAM domain containing 1Ba
chr11_+_30057762 0.86 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr13_+_23282549 0.85 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr24_+_3328354 0.85 ENSDART00000147468
bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr9_+_44430705 0.84 ENSDART00000190696
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_+_25783801 0.84 ENSDART00000102455
gucy1a1
guanylate cyclase 1 soluble subunit alpha 1
chr10_+_38775959 0.83 ENSDART00000192990
dscama
Down syndrome cell adhesion molecule a
chr9_+_16449398 0.83 ENSDART00000006787
epha3
eph receptor A3
chr23_+_6232895 0.82 ENSDART00000139795
syt2a
synaptotagmin IIa
chr8_-_39952727 0.82 ENSDART00000181310
cabp1a
calcium binding protein 1a
chr7_+_12371061 0.81 ENSDART00000053860
saxo2
stabilizer of axonemal microtubules 2
chr2_-_22286828 0.81 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr21_+_26389391 0.81 ENSDART00000077197
tmsb
thymosin, beta
chr10_+_38775408 0.81 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr9_+_11034967 0.81 ENSDART00000152081
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr16_+_29630965 0.80 ENSDART00000185820
ENSDART00000192105
ENSDART00000153683
ENSDART00000186713
VPS72
si:ch211-203d17.1
chr6_-_6423885 0.80 ENSDART00000092257
si:ch211-194e18.2
si:ch211-194e18.2
chr23_-_30431333 0.79 ENSDART00000146633
camta1a
calmodulin binding transcription activator 1a
chr17_+_9009098 0.79 ENSDART00000180856
akap6
A kinase (PRKA) anchor protein 6
chr13_+_8604710 0.79 ENSDART00000091097
socs5b
suppressor of cytokine signaling 5b
chr20_+_20750284 0.78 ENSDART00000181524
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr2_-_24348948 0.77 ENSDART00000136559
ano8a
anoctamin 8a
chr11_+_34523132 0.77 ENSDART00000192257
zmat3
zinc finger, matrin-type 3
chr14_-_47849216 0.77 ENSDART00000192796
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_5422439 0.76 ENSDART00000055047
ENSDART00000142248
stk16
serine/threonine kinase 16
chr14_+_36231126 0.76 ENSDART00000141766
elovl6
ELOVL fatty acid elongase 6
chr5_-_41103583 0.75 ENSDART00000051070
ENSDART00000074781
golph3
golgi phosphoprotein 3
chr13_+_12299997 0.73 ENSDART00000108535
gabrb1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr11_+_19060079 0.72 ENSDART00000158123
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr25_-_4148719 0.72 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr17_+_15983247 0.72 ENSDART00000154275
clmn
calmin
chr13_+_36622100 0.72 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr10_-_27566481 0.72 ENSDART00000078920
auts2a
autism susceptibility candidate 2a
chr22_-_32360464 0.71 ENSDART00000148886
pcbp4
poly(rC) binding protein 4
chr8_+_30600386 0.69 ENSDART00000164976
specc1la
sperm antigen with calponin homology and coiled-coil domains 1-like a
chr7_+_7019911 0.68 ENSDART00000172421
rbm14b
RNA binding motif protein 14b
chr5_-_26323137 0.67 ENSDART00000133823
arvcfb
ARVCF, delta catenin family member b
chr22_-_17585618 0.67 ENSDART00000183123
pip5k1ca
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr3_+_33440615 0.67 ENSDART00000146005
gtpbp1
GTP binding protein 1
chr2_+_22042745 0.66 ENSDART00000132039
tox
thymocyte selection-associated high mobility group box
chr18_-_23875370 0.65 ENSDART00000130163
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr2_-_30784198 0.64 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr11_+_19370447 0.63 ENSDART00000186154
prickle2b
prickle homolog 2b
chr9_+_11034314 0.62 ENSDART00000032695
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr2_-_24348642 0.62 ENSDART00000181739
ano8a
anoctamin 8a
chr15_-_11681653 0.62 ENSDART00000180160
fkrp
fukutin related protein
chr19_-_47455944 0.62 ENSDART00000190005
tfap2e
transcription factor AP-2 epsilon
chr20_-_11178022 0.60 ENSDART00000152246
flrt2
fibronectin leucine rich transmembrane protein 2
chr21_+_27278120 0.60 ENSDART00000193882
si:dkey-175m17.7
si:dkey-175m17.7
chr20_-_31075972 0.59 ENSDART00000122927
si:ch211-198b3.4
si:ch211-198b3.4
chr19_-_43552252 0.59 ENSDART00000138308
gpr186
G protein-coupled receptor 186
chr5_+_42393896 0.57 ENSDART00000189550
BX548073.13

chr7_+_27059330 0.57 ENSDART00000173919
plekha7b
pleckstrin homology domain containing, family A member 7b
chr11_-_1956204 0.57 ENSDART00000185541
nr1d4b
nuclear receptor subfamily 1, group D, member 4b
chr1_-_21901589 0.55 ENSDART00000140553
frmpd1a
FERM and PDZ domain containing 1a
chr22_-_29906764 0.54 ENSDART00000019786
smc3
structural maintenance of chromosomes 3
chr13_-_32635859 0.54 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr2_+_32846602 0.53 ENSDART00000056649
tmem53
transmembrane protein 53
chr12_-_19151708 0.53 ENSDART00000057124
tefa
thyrotrophic embryonic factor a
chr12_+_8168272 0.53 ENSDART00000054092
arid5b
AT-rich interaction domain 5B
chr22_+_11153590 0.52 ENSDART00000188207
bcor
BCL6 corepressor
chr9_-_40931637 0.52 ENSDART00000165103
C2orf88
Small membrane A-kinase anchor protein
chr8_-_22838364 0.52 ENSDART00000187954
ENSDART00000185368
ENSDART00000188210
magixa
MAGI family member, X-linked a
chr3_-_45250924 0.51 ENSDART00000109017
usp31
ubiquitin specific peptidase 31
chr19_-_3574060 0.51 ENSDART00000105120
tmem170b
transmembrane protein 170B
chr13_+_1944451 0.50 ENSDART00000125914
hmgcll1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr20_-_10120442 0.49 ENSDART00000144970
meis2b
Meis homeobox 2b
chr9_+_44431174 0.48 ENSDART00000149726
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr7_-_25895189 0.48 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr17_+_2162916 0.47 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr2_+_38742338 0.47 ENSDART00000177290
carmil3
capping protein regulator and myosin 1 linker 3
chr17_-_8673278 0.46 ENSDART00000171850
ENSDART00000017337
ENSDART00000148504
ENSDART00000148808
ctbp2a
C-terminal binding protein 2a
chr7_-_71829649 0.46 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr24_+_17142881 0.46 ENSDART00000177272
ENSDART00000192259
ENSDART00000191029
mllt10
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr23_+_21479958 0.45 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
si:dkey-1c11.1
chr1_+_22851261 0.45 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr13_-_30700460 0.45 ENSDART00000139073
rassf4
Ras association (RalGDS/AF-6) domain family member 4
chr20_-_2361226 0.44 ENSDART00000172130
EPB41L2
si:ch73-18b11.1
chr18_+_40355408 0.44 ENSDART00000167134
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr20_+_30610547 0.43 ENSDART00000122256
ccr6a
chemokine (C-C motif) receptor 6a
chr1_-_44581937 0.43 ENSDART00000009858
tmx2b
thioredoxin-related transmembrane protein 2b
chr17_+_15983557 0.43 ENSDART00000190806
clmn
calmin
chr20_-_39103119 0.42 ENSDART00000143379
rcan2
regulator of calcineurin 2
chr17_-_8673567 0.42 ENSDART00000192714
ENSDART00000012546
ctbp2a
C-terminal binding protein 2a
chr15_-_14469704 0.41 ENSDART00000185077
numbl
numb homolog (Drosophila)-like
chr19_-_45960191 0.41 ENSDART00000052434
ENSDART00000172732
eif3hb
eukaryotic translation initiation factor 3, subunit H, b
chr4_-_9173552 0.41 ENSDART00000042963
chst11
carbohydrate (chondroitin 4) sulfotransferase 11
chr20_-_40766387 0.40 ENSDART00000061173
hsdl1
hydroxysteroid dehydrogenase like 1
chr7_+_6941583 0.39 ENSDART00000160709
ENSDART00000157634
rbm14b
RNA binding motif protein 14b
chr20_-_6196989 0.39 ENSDART00000013343
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6

Network of associatons between targets according to the STRING database.

First level regulatory network of pou4f3_pou4f1+pou4f4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0007638 mechanosensory behavior(GO:0007638)
1.0 3.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.7 2.9 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.7 6.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.5 1.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3 0.9 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.3 0.9 GO:0090247 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.3 0.8 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.3 1.1 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.2 4.1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.2 0.7 GO:0060843 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
0.2 3.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 2.6 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 1.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 2.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 2.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 1.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.7 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.9 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.6 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.5 GO:0001964 startle response(GO:0001964)
0.1 2.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.9 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 1.6 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.8 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 1.9 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 3.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 1.7 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.1 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 1.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.0 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.3 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.3 GO:0015871 choline transport(GO:0015871)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 1.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.0 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 0.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 2.0 GO:0050708 regulation of protein secretion(GO:0050708)
0.1 1.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 2.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.6 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 5.2 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.5 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.5 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 2.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 1.4 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.1 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)
0.0 1.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 2.4 GO:0006865 amino acid transport(GO:0006865)
0.0 0.5 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.6 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 1.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 2.2 GO:0030041 actin filament polymerization(GO:0030041)
0.0 3.2 GO:0030334 regulation of cell migration(GO:0030334)
0.0 0.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.3 0.9 GO:0097189 apoptotic body(GO:0097189)
0.3 7.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 3.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 4.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 6.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.9 GO:0014704 intercalated disc(GO:0014704)
0.1 2.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 1.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.9 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 3.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 4.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.3 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 2.2 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.8 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.6 1.9 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.4 8.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 0.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.0 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 1.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 2.6 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 1.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 2.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 0.5 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 2.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 2.0 GO:0045159 myosin II binding(GO:0045159)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 8.5 GO:0005254 chloride channel activity(GO:0005254)
0.1 1.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 3.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0070122 isopeptidase activity(GO:0070122)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 3.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.7 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 1.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 5.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.4 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 1.6 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism