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PRJNA207719: Tissue specific transcriptome profiling

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Results for pou5f3

Z-value: 0.69

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Transcription factors associated with pou5f3

Gene Symbol Gene ID Gene Info
pou5f3
ENSDARG00000044774 POU domain, class 5, transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou5f3dr11_v1_chr21_-_13690712_13690712-0.247.0e-01Click!

Activity profile of pou5f3 motif

Sorted Z-values of pou5f3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_40994259 0.63 ENSDART00000101562
adra2c
adrenoceptor alpha 2C
chr4_-_8903240 0.60 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr4_-_5302162 0.53 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr7_+_61050329 0.50 ENSDART00000115355
nwd2
NACHT and WD repeat domain containing 2
chr22_+_15507218 0.43 ENSDART00000125450
gpc1a
glypican 1a
chr21_+_39361040 0.43 ENSDART00000085453
cluhb
clustered mitochondria (cluA/CLU1) homolog b
chr22_+_5106751 0.42 ENSDART00000138967
atcaya
ataxia, cerebellar, Cayman type a
chr13_-_39830999 0.41 ENSDART00000115089
zgc:171482
zgc:171482
chr7_-_72155022 0.41 ENSDART00000187984
zmp:0000001168
zmp:0000001168
chr11_-_36001495 0.40 ENSDART00000190330
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr8_-_22698651 0.38 ENSDART00000181411
iqsec2a
IQ motif and Sec7 domain 2a
chr8_+_7740004 0.37 ENSDART00000170184
ENSDART00000187811
fgd1
FYVE, RhoGEF and PH domain containing 1
chr19_-_43552252 0.37 ENSDART00000138308
gpr186
G protein-coupled receptor 186
chr8_-_16592491 0.32 ENSDART00000101655
calr
calreticulin
chr24_-_21989406 0.32 ENSDART00000032963
apoob
apolipoprotein O, b
chr20_-_34868814 0.32 ENSDART00000153049
stmn4
stathmin-like 4
chr11_+_7528599 0.30 ENSDART00000171813
adgrl2a
adhesion G protein-coupled receptor L2a
chr24_-_20641000 0.28 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr25_+_26923193 0.26 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr9_+_12444494 0.24 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr8_+_43016714 0.22 ENSDART00000142671
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr11_+_19060278 0.21 ENSDART00000164294
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr24_+_3328354 0.17 ENSDART00000147468
bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr13_+_18545819 0.15 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
zgc:154058
chr2_-_20120904 0.15 ENSDART00000186002
ENSDART00000124724
dpydb
dihydropyrimidine dehydrogenase b
chr11_+_19060079 0.14 ENSDART00000158123
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr13_+_31172833 0.13 ENSDART00000176378
CR931802.3

chr7_-_24644893 0.13 ENSDART00000048921
rgp1
GP1 homolog, RAB6A GEF complex partner 1
chr16_-_31351419 0.13 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr24_-_25004553 0.12 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr24_+_17007407 0.12 ENSDART00000110652
zfx
zinc finger protein, X-linked
chr8_-_44238526 0.12 ENSDART00000061115
ENSDART00000132473
ENSDART00000138019
ENSDART00000133021
piwil1
piwi-like RNA-mediated gene silencing 1
chr7_+_33424044 0.11 ENSDART00000180260
glceb
glucuronic acid epimerase b
chr18_+_7543347 0.08 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr4_+_6869847 0.06 ENSDART00000036646
dock4b
dedicator of cytokinesis 4b
chr24_-_7321928 0.04 ENSDART00000167570
ENSDART00000045150
actr3b
ARP3 actin related protein 3 homolog B
chr11_+_13193747 0.04 ENSDART00000173336
si:dkey-9a6.4
si:dkey-9a6.4

Network of associatons between targets according to the STRING database.

First level regulatory network of pou5f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.1 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.4 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha