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PRJNA207719: Tissue specific transcriptome profiling

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Results for prdm4

Z-value: 0.71

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Transcription factors associated with prdm4

Gene Symbol Gene ID Gene Info
prdm4
ENSDARG00000017366 PR domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prdm4dr11_v1_chr4_-_14926106_149261060.296.3e-01Click!

Activity profile of prdm4 motif

Sorted Z-values of prdm4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_31621774 0.85 ENSDART00000076636
fzd2
frizzled class receptor 2
chr9_+_41690153 0.46 ENSDART00000100226
ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr9_-_13355071 0.44 ENSDART00000084055
fzd7a
frizzled class receptor 7a
chr23_-_24682244 0.43 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chrM_+_9735 0.39 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr22_-_21046843 0.35 ENSDART00000133982
ssbp4
single stranded DNA binding protein 4
chr22_-_21046654 0.27 ENSDART00000064902
ssbp4
single stranded DNA binding protein 4
chr9_+_15893093 0.17 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
si:dkey-14o1.20
chr11_-_6868474 0.17 ENSDART00000168372
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr24_+_29912509 0.15 ENSDART00000168422
frrs1b
ferric-chelate reductase 1b
chr4_-_2868112 0.15 ENSDART00000133843
pde3a
phosphodiesterase 3A, cGMP-inhibited
chr11_-_6868287 0.14 ENSDART00000037824
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr21_-_37027252 0.13 ENSDART00000076483
zgc:77151
zgc:77151
chr5_+_27442247 0.11 ENSDART00000184129
loxl2b
lysyl oxidase-like 2b
chr17_+_31611854 0.10 ENSDART00000011706
adprhl2
ADP-ribosylhydrolase like 2
chr6_-_9707599 0.10 ENSDART00000039280
fzd7b
frizzled class receptor 7b
chr10_+_43037064 0.09 ENSDART00000160159
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr3_+_32425202 0.09 ENSDART00000156464
prr12b
proline rich 12b
chr4_-_2867461 0.08 ENSDART00000160308
pde3a
phosphodiesterase 3A, cGMP-inhibited
chr10_-_3332362 0.08 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr1_+_12348213 0.06 ENSDART00000144920
ENSDART00000138759
ENSDART00000067082
clta
clathrin, light chain A
chr19_+_2670130 0.05 ENSDART00000152152
si:ch73-24k9.2
si:ch73-24k9.2
chr20_-_26001288 0.02 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr2_-_41723165 0.02 ENSDART00000155577
zgc:110158
zgc:110158
chr3_+_40407352 0.00 ENSDART00000155112
tnrc18
trinucleotide repeat containing 18

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects