ISMARA results: prdm4

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PRJNA207719: Tissue specific transcriptome profiling

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Results for prdm4

Z-value: 0.71

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Transcription factors associated with prdm4

Gene Symbol	Gene ID	Gene Info
prdm4 NCBI UniProt	ENSDARG00000017366	PR domain containing 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
prdm4	dr11_v1_chr4_-_14926106_14926106	0.29	6.3e-01	Click!

Activity profile of prdm4 motif

Sorted Z-values of prdm4 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_+_31621774 Show fit	0.85	ENSDART00000076636	fzd2 NCBI UniProt Show fit	frizzled class receptor 2
chr9_+_41690153 Show fit	0.46	ENSDART00000100226	ctdsp1 NCBI UniProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr9_-_13355071 Show fit	0.44	ENSDART00000084055	fzd7a NCBI UniProt Show fit	frizzled class receptor 7a
chr23_-_24682244 Show fit	0.43	ENSDART00000104035	ctdsp2 NCBI UniProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chrM_+_9735 Show fit	0.39	ENSDART00000093613	mt-co3 NCBI UniProt Show fit	cytochrome c oxidase III, mitochondrial
chr22_-_21046843 Show fit	0.35	ENSDART00000133982	ssbp4 NCBI UniProt Show fit	single stranded DNA binding protein 4
chr22_-_21046654 Show fit	0.27	ENSDART00000064902	ssbp4 NCBI UniProt Show fit	single stranded DNA binding protein 4
chr9_+_15893093 Show fit	0.17	ENSDART00000099483 ENSDART00000134657	si:dkey-14o1.20 NCBI UniProt Show fit	si:dkey-14o1.20
chr11_-_6868474 Show fit	0.17	ENSDART00000168372	lsm4 NCBI UniProt Show fit	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr24_+_29912509 Show fit	0.15	ENSDART00000168422	frrs1b NCBI UniProt Show fit	ferric-chelate reductase 1b

Showing 1 to 10 of 25 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0061341	non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1	0.4	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.3	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)

Showing 1 to 6 of 6 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0005688	U6 snRNP(GO:0005688)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.9	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.4	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0019777	Atg12 transferase activity(GO:0019777)

Showing 1 to 6 of 6 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network

Showing 1 to 2 of 2 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Total log-likelihood	Term	Description
0.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects

Showing 1 to 3 of 3 entries

Results for prdm4

Z-value: 0.71

Motif logo

Transcription factors associated with prdm4

Activity-expression correlation:

Activity profile of prdm4 motif

Sorted Z-values of prdm4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: