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PRJNA207719: Tissue specific transcriptome profiling

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Results for prrx1a+prrx1b

Z-value: 0.86

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Transcription factors associated with prrx1a+prrx1b

Gene Symbol Gene ID Gene Info
ENSDARG00000033971 paired related homeobox 1a
ENSDARG00000042027 paired related homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prrx1bdr11_v1_chr20_+_34512130_34512130-0.662.3e-01Click!
prrx1adr11_v1_chr2_-_23172708_23172708-0.533.6e-01Click!

Activity profile of prrx1a+prrx1b motif

Sorted Z-values of prrx1a+prrx1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 1.82 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr1_+_17676745 0.63 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr16_-_22294265 0.60 ENSDART00000124718
aquaporin 10a
chr6_+_23887314 0.56 ENSDART00000163188
zinc finger protein 648
chr2_+_38039857 0.50 ENSDART00000159951
calsequestrin 1a
chr20_+_31287356 0.49 ENSDART00000007688
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr25_+_31267268 0.47 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr11_+_36243774 0.47 ENSDART00000023323
zgc:172270
chr23_+_26026383 0.45 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr21_+_27382893 0.43 ENSDART00000005682
actinin alpha 3a
chr21_+_6556635 0.38 ENSDART00000139598
procollagen, type V, alpha 1
chr7_+_66822229 0.37 ENSDART00000112109
lymphatic vessel endothelial hyaluronic receptor 1a
chr2_-_39558643 0.36 ENSDART00000139860
ENSDART00000145231
ENSDART00000141721
cerebellin 7
chr18_+_5490668 0.36 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr2_+_30916188 0.35 ENSDART00000137012
myomesin 1a (skelemin)
chr11_-_34097418 0.34 ENSDART00000028301
ENSDART00000138579
tryptophan 2,3-dioxygenase b
chr10_+_23537576 0.34 ENSDART00000130515

chr13_-_31622195 0.33 ENSDART00000057432
SIX homeobox 1a
chr16_-_42872571 0.33 ENSDART00000154757
ENSDART00000102345
thioredoxin interacting protein b
chr25_+_29160102 0.32 ENSDART00000162854
pyruvate kinase M1/2b
chr2_+_16781015 0.32 ENSDART00000155147
ENSDART00000003845
transferrin-a
chr1_-_56080112 0.31 ENSDART00000075469
ENSDART00000161473
complement component c3a, duplicate 6
chr25_+_31277415 0.30 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr16_+_23984755 0.30 ENSDART00000145328
apolipoprotein C-II
chr22_-_23668356 0.29 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
complement factor H
chr2_+_37227011 0.29 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr6_+_6924637 0.29 ENSDART00000065551
ENSDART00000151393
sterile alpha motif and leucine zipper containing kinase AZK
chr21_-_20757866 0.28 ENSDART00000163003
growth hormone receptor b
chr7_+_20147202 0.28 ENSDART00000011398
si:ch73-335l21.1
chr13_+_24279021 0.27 ENSDART00000058629
actin, alpha 1b, skeletal muscle
chr16_-_27749172 0.27 ENSDART00000145198
STEAP family member 4
chr15_-_21165237 0.26 ENSDART00000157069
si:ch211-212c13.8
chr15_-_14625373 0.25 ENSDART00000171841
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr14_-_21123551 0.25 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
chr19_-_5669122 0.25 ENSDART00000112211
si:ch211-264f5.2
chr17_+_30704068 0.25 ENSDART00000062793
apolipoprotein Ba
chr22_+_21324398 0.25 ENSDART00000168509
SHC (Src homology 2 domain containing) transforming protein 2
chr12_-_25294769 0.24 ENSDART00000153306
hydroxycarboxylic acid receptor 1-4
chr7_+_41303572 0.24 ENSDART00000012692
regulator of G protein signaling 9 binding protein
chr11_+_13224281 0.24 ENSDART00000102557
ENSDART00000178706
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr2_+_20605186 0.23 ENSDART00000128505
olfactomedin-like 2Bb
chr17_+_43863708 0.23 ENSDART00000133874
ENSDART00000140316
ENSDART00000142929
ENSDART00000148090
zgc:66313
chr23_+_41679586 0.23 ENSDART00000067662

chr8_-_39739056 0.23 ENSDART00000147992
si:ch211-170d8.5
chr6_+_43234213 0.23 ENSDART00000112474
ADP-ribosylation factor-like 6 interacting protein 5a
chr1_-_49250490 0.22 ENSDART00000150386
si:ch73-6k14.2
chr9_-_394088 0.21 ENSDART00000169014
si:dkey-11f4.7
chr23_+_28770225 0.21 ENSDART00000132179
ENSDART00000142273
mannan-binding lectin serine peptidase 2
chr7_+_56098590 0.21 ENSDART00000098453
cadherin 15, type 1, M-cadherin (myotubule)
chr24_+_21346796 0.21 ENSDART00000126519
shisa family member 2b
chr2_+_20604775 0.20 ENSDART00000131501
olfactomedin-like 2Bb
chr11_+_2391649 0.20 ENSDART00000104571
insulin-like growth factor binding protein 6a
chr4_-_2945306 0.20 ENSDART00000128934
ENSDART00000019518
AE binding protein 2
chr25_-_13728111 0.20 ENSDART00000169865
lecithin-cholesterol acyltransferase
chr8_+_50190742 0.19 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr8_+_15254564 0.19 ENSDART00000024433
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr12_+_2428247 0.19 ENSDART00000152529
leucine rich repeat containing 18b
chr25_+_34641536 0.19 ENSDART00000167033

chr2_-_38284648 0.18 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
chr22_-_910926 0.18 ENSDART00000180075

chr4_+_2267641 0.18 ENSDART00000165503
si:ch73-89b15.3
chr19_-_25113660 0.18 ENSDART00000035538
protein tyrosine phosphatase type IVA, member 3
chr21_-_42831033 0.18 ENSDART00000160998
serine/threonine kinase 10
chr10_+_34001444 0.18 ENSDART00000149934
klotho
chr24_-_38657683 0.18 ENSDART00000154843
si:ch1073-164k15.3
chr24_-_25098719 0.18 ENSDART00000193651
pleckstrin homology-like domain, family B, member 2b
chr16_+_29509133 0.18 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr16_-_42066523 0.18 ENSDART00000180538
ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr1_+_12009673 0.18 ENSDART00000080100
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr23_+_39695827 0.18 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr5_+_57924611 0.18 ENSDART00000050949
B-cell translocation gene 4
chr6_+_41191482 0.17 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr11_+_13223625 0.17 ENSDART00000161275
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr23_+_45282858 0.17 ENSDART00000162353

chr22_-_24284447 0.17 ENSDART00000149894
si:ch211-117l17.4
chr6_+_8626427 0.17 ENSDART00000193660
thrombospondin-type laminin G domain and EAR repeats a
chr10_-_21545091 0.16 ENSDART00000029122
ENSDART00000132207
zgc:165539
chr22_-_38274188 0.16 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr14_-_46173265 0.16 ENSDART00000164321
zmp:0000000758
chr25_-_10769039 0.15 ENSDART00000186758
ENSDART00000121724
low density lipoprotein receptor-related protein 5
chr1_-_18811517 0.15 ENSDART00000142026
si:dkey-167i21.2
chr5_+_20613466 0.15 ENSDART00000161209
ENSDART00000136632
si:ch211-240b21.5
chr9_+_29548195 0.15 ENSDART00000176057
ring finger protein 17
chr18_-_8030073 0.15 ENSDART00000151490
SH3 and multiple ankyrin repeat domains 3a
chr23_-_36441693 0.15 ENSDART00000024354
cysteine sulfinic acid decarboxylase
chr10_+_45031398 0.15 ENSDART00000160536
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr1_-_9195629 0.15 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr25_+_20089986 0.15 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr16_-_16761164 0.15 ENSDART00000135872
si:dkey-27n14.1
chr25_+_3327071 0.15 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr19_-_47323267 0.15 ENSDART00000190077

chr12_-_25294096 0.15 ENSDART00000183398
hydroxycarboxylic acid receptor 1-4
chr16_-_31598771 0.15 ENSDART00000016386
thyroglobulin
chr8_+_25034544 0.15 ENSDART00000123300
neugrin, neurite outgrowth associated
chr5_-_43859148 0.14 ENSDART00000162746
ENSDART00000128763
si:ch211-204c21.1
chr20_+_37393134 0.14 ENSDART00000128321
adhesion G protein-coupled receptor G6
chr6_+_37894220 0.14 ENSDART00000087311
oculocutaneous albinism II
chr5_-_7199998 0.14 ENSDART00000167316

chr8_-_18203274 0.14 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
ELOVL fatty acid elongase 8b
chr2_-_51303937 0.14 ENSDART00000164111
si:ch211-215e19.8
chr4_-_77331797 0.14 ENSDART00000162325
solute carrier organic anion transporter family, member 1F3
chr3_+_32594357 0.13 ENSDART00000151639
unc-119 lipid binding chaperone B homolog 2
chr21_-_28439596 0.13 ENSDART00000089980
ENSDART00000132844
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr22_-_38274995 0.13 ENSDART00000179786
ELAV like neuron-specific RNA binding protein 2
chr25_+_31227747 0.13 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr21_-_20733615 0.13 ENSDART00000145544
si:ch211-22d5.2
chr6_+_3334710 0.13 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr3_-_32170850 0.13 ENSDART00000055307
ENSDART00000157366
troponin T type 1 (skeletal, slow)
chr9_+_47966167 0.13 ENSDART00000183345
G protein-coupled bile acid receptor 1
chr20_+_23498255 0.13 ENSDART00000149922
palladin, cytoskeletal associated protein
chr12_+_27231607 0.13 ENSDART00000066270
transmembrane protein 106A
chr21_+_5272059 0.13 ENSDART00000141981
lipoxygenase homology domains 1a
chr25_+_10923100 0.13 ENSDART00000157055
si:ch211-147g22.7
chr7_-_55648336 0.12 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr5_+_40224938 0.12 ENSDART00000142897
si:dkey-193c22.2
chr13_-_9091354 0.12 ENSDART00000140319
ENSDART00000142697
si:dkey-112g5.13
chr15_+_17030941 0.12 ENSDART00000062069
perilipin 2
chr14_-_29826659 0.12 ENSDART00000138413
sorbin and SH3 domain containing 2b
chr24_-_25442342 0.12 ENSDART00000177140
ENSDART00000138215
phosphate regulating endopeptidase homolog, X-linked
chr11_-_26375575 0.12 ENSDART00000079255
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr15_-_18213515 0.12 ENSDART00000101635
bloodthirsty-related gene family, member 21
chr5_-_57655092 0.12 ENSDART00000074290
melanoma inhibitory activity
chr3_-_16493528 0.12 ENSDART00000142099
si:ch211-23l10.3
chr21_+_26720803 0.12 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr1_-_43684584 0.12 ENSDART00000074609
succinate-CoA ligase, alpha subunit
chr20_-_30920356 0.12 ENSDART00000022951
kinesin family member 25
chr17_-_13058515 0.12 ENSDART00000172450
ENSDART00000170255

chr10_-_34107919 0.11 ENSDART00000167428
ENSDART00000145279
Pim proto-oncogene, serine/threonine kinase, related 144
Pim proto-oncogene, serine/threonine kinase, related 146
chr12_+_27232173 0.11 ENSDART00000193714
transmembrane protein 106A
chr14_+_5835134 0.11 ENSDART00000054867
ancient ubiquitous protein 1
chr3_+_16922226 0.11 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr1_+_15204633 0.11 ENSDART00000188410
intelectin 1
chr1_-_45049603 0.11 ENSDART00000023336
ribosomal protein S6
chr23_+_32101202 0.11 ENSDART00000000992
zgc:56699
chr9_+_55455801 0.11 ENSDART00000144757
ENSDART00000186543
matrix-remodelling associated 5b
chr24_+_24086491 0.11 ENSDART00000145092
lipase, member Ib
chr22_+_1821718 0.11 ENSDART00000132220
zinc finger protein 1002
chr15_+_36096689 0.11 ENSDART00000049849
collagen, type IV, alpha 3
chr22_+_5971404 0.11 ENSDART00000122153

chr5_-_39698224 0.11 ENSDART00000076929
protein kinase, cGMP-dependent, type II
chr23_-_31763753 0.11 ENSDART00000053399
aldehyde dehydrogenase 8 family, member A1
chr3_+_26019426 0.11 ENSDART00000135389
ENSDART00000182411
FAD-dependent oxidoreductase domain containing 2
chr25_-_19648154 0.11 ENSDART00000148570
ATPase plasma membrane Ca2+ transporting 1b
chr18_+_33171765 0.11 ENSDART00000064153
si:ch73-125k17.2
chr13_-_41901225 0.10 ENSDART00000167582
inositol polyphosphate multikinase a
chr4_-_16345227 0.10 ENSDART00000079521
keratocan
chr15_-_17813680 0.10 ENSDART00000158556

chr7_+_20030888 0.10 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr7_+_48667081 0.10 ENSDART00000083473
transient receptor potential cation channel, subfamily M, member 5
chr11_+_2391469 0.10 ENSDART00000182121
insulin-like growth factor binding protein 6a
chr20_-_7583486 0.10 ENSDART00000144729
ubiquitin specific peptidase 24
chr12_-_990149 0.10 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr13_+_30228077 0.10 ENSDART00000100813
ENSDART00000147729
ENSDART00000133404
ribosomal protein S24
chr2_+_15203322 0.10 ENSDART00000144171
ATP-binding cassette, sub-family A (ABC1), member 4b
chr1_-_42289704 0.10 ENSDART00000150124
si:ch211-71k14.1
chr7_-_27685365 0.10 ENSDART00000188342
calcitonin/calcitonin-related polypeptide, alpha
chr21_+_21817975 0.10 ENSDART00000151292
ENSDART00000166704
sialidase 3 (membrane sialidase), tandem duplicate 5
chr14_-_899170 0.10 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr7_-_6467510 0.10 ENSDART00000166041
Histone H3.2
chr13_-_29505604 0.10 ENSDART00000110005
cadherin-related family member 1a
chr21_+_42717424 0.10 ENSDART00000166936
ENSDART00000172135
SH3 and PX domains 2B
chr7_+_54222156 0.10 ENSDART00000165201
ENSDART00000158518
protein kinase C and casein kinase substrate in neurons 3
chr5_-_12063381 0.10 ENSDART00000026749
nipsnap homolog 1 (C. elegans)
chr6_+_39942417 0.10 ENSDART00000183256
inositol 1,4,5-trisphosphate receptor, type 1a
chr8_-_43834442 0.10 ENSDART00000191927
adhesion G protein-coupled receptor D1
chr21_+_43404945 0.10 ENSDART00000142234
FERM domain containing 7
chr20_-_27225876 0.10 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
chr4_-_16001118 0.10 ENSDART00000041070
ENSDART00000125389
mesoderm specific transcript
chr22_-_10470663 0.10 ENSDART00000143352
osteomodulin
chr12_+_16281312 0.10 ENSDART00000152500
protein phosphatase 1, regulatory subunit 3Cb
chr11_-_45148743 0.10 ENSDART00000187124
ENSDART00000172878
ENSDART00000170993
calcium activated nucleotidase 1b
arylformamidase
chr5_-_30481263 0.10 ENSDART00000086734
pleckstrin homology-like domain, family B, member 1a
chr5_-_23715861 0.10 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr6_+_43426599 0.10 ENSDART00000056457
microphthalmia-associated transcription factor a
chr20_+_48129759 0.09 ENSDART00000148494
translocation associated membrane protein 2
chr7_-_48667056 0.09 ENSDART00000006378
cyclin-dependent kinase inhibitor 1Ca
chr23_+_20689255 0.09 ENSDART00000182420
ubiquitin specific peptidase 21
chr16_-_16643377 0.09 ENSDART00000185748
tenascin XBa
chr8_+_2575993 0.09 ENSDART00000112914
si:ch211-51h9.7
chr18_-_16801033 0.09 ENSDART00000100100
adrenomedullin b
chr14_-_17068712 0.09 ENSDART00000170277
paired-like homeobox 2bb
chr3_-_13921173 0.09 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
chr13_-_31017960 0.09 ENSDART00000145287
WDFY family member 4
chr17_+_21486047 0.09 ENSDART00000104608
phospholipase A2, group IVF, tandem duplicate 2
chr5_+_6672870 0.09 ENSDART00000126598
paxillin a
chr1_+_44003654 0.09 ENSDART00000131337
si:dkey-22i16.10
chr10_-_34089779 0.09 ENSDART00000140070
Pim proto-oncogene, serine/threonine kinase, related 144
chr7_+_22586800 0.09 ENSDART00000035325
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr4_+_39742119 0.09 ENSDART00000176004

chr12_+_18663154 0.09 ENSDART00000057918
si:ch211-147h1.4
chr14_+_44794936 0.09 ENSDART00000128881
zgc:195212
chr20_-_43775495 0.09 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matrilin 3a
chr14_+_8715527 0.09 ENSDART00000170754
potassium channel, subfamily K, member 4a
chr3_-_5555500 0.09 ENSDART00000176133
ENSDART00000057464
tripartite motif containing 35-31
chr19_+_10339538 0.09 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr12_+_20412564 0.09 ENSDART00000186783
Rho GTPase activating protein 17a
chr19_+_15440841 0.09 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr10_-_34200750 0.09 ENSDART00000137279
Pim proto-oncogene, serine/threonine kinase, related 148
chr2_+_50967947 0.08 ENSDART00000162288
si:ch211-249o11.5
chr4_+_53268458 0.08 ENSDART00000165335
si:dkey-250k10.1

Network of associatons between targets according to the STRING database.

First level regulatory network of prrx1a+prrx1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.6 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.4 GO:0015695 organic cation transport(GO:0015695)
0.1 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.4 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.3 GO:0014857 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.1 0.3 GO:0015677 copper ion import(GO:0015677)
0.1 0.2 GO:0060292 long term synaptic depression(GO:0060292)
0.1 3.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.2 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.0 0.5 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.4 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.2 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 3.0 GO:0005861 troponin complex(GO:0005861)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.0 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.6 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.1 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.4 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.3 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.2 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions