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PRJNA207719: Tissue specific transcriptome profiling

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Results for roraa+rorab

Z-value: 0.86

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Transcription factors associated with roraa+rorab

Gene Symbol Gene ID Gene Info
rorab
ENSDARG00000001910 RAR-related orphan receptor A, paralog b
roraa
ENSDARG00000031768 RAR-related orphan receptor A, paralog a
rorab
ENSDARG00000109324 RAR-related orphan receptor A, paralog b
rorab
ENSDARG00000113275 RAR-related orphan receptor A, paralog b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
roraadr11_v1_chr25_+_33939728_339397280.866.4e-02Click!
rorabdr11_v1_chr7_-_29625509_296255090.847.7e-02Click!

Activity profile of roraa+rorab motif

Sorted Z-values of roraa+rorab motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_5678071 0.88 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
zgc:158689
chr25_-_19374710 0.86 ENSDART00000184483
ENSDART00000188706
map1ab
microtubule-associated protein 1Ab
chr1_+_12763920 0.81 ENSDART00000189465
pcdh10a
protocadherin 10a
chr2_+_34767171 0.75 ENSDART00000145451
astn1
astrotactin 1
chr4_+_2620751 0.70 ENSDART00000013924
gpr22a
G protein-coupled receptor 22a
chr10_-_17103651 0.67 ENSDART00000108959
RNF208
ring finger protein 208
chr23_+_19564392 0.66 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr7_+_29133321 0.66 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr16_-_28856112 0.66 ENSDART00000078543
syt11b
synaptotagmin XIb
chr17_+_22381215 0.65 ENSDART00000162670
ENSDART00000128875
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr23_+_44741500 0.62 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr14_-_33454595 0.61 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr1_-_23110740 0.60 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr3_-_19091024 0.60 ENSDART00000188485
ENSDART00000110554
grin2ca
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr7_+_40228422 0.60 ENSDART00000052222
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr19_+_30662529 0.60 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr20_+_5564042 0.58 ENSDART00000090934
ENSDART00000127050
nrxn3b
neurexin 3b
chr23_-_19953089 0.56 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr7_+_50109239 0.56 ENSDART00000021605
LRRC4C (1 of many)
si:dkey-6l15.1
chr21_+_7582036 0.55 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr10_+_1638876 0.55 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
sgsm1b
small G protein signaling modulator 1b
chr22_-_11124419 0.54 ENSDART00000149634
atp6ap2
ATPase H+ transporting accessory protein 2
chr18_+_45571378 0.53 ENSDART00000077251
kifc3
kinesin family member C3
chr3_-_60142530 0.52 ENSDART00000153247
si:ch211-120g10.1
si:ch211-120g10.1
chr14_-_31465905 0.51 ENSDART00000173108
gpc3
glypican 3
chr18_-_42333428 0.51 ENSDART00000034225
cntn5
contactin 5
chr10_+_17850934 0.49 ENSDART00000113666
ENSDART00000145936
phf24
PHD finger protein 24
chr7_+_67494107 0.49 ENSDART00000185653
cpne7
copine VII
chr11_+_28476298 0.48 ENSDART00000122319
lrrc38b
leucine rich repeat containing 38b
chr17_+_25290136 0.47 ENSDART00000173295
kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr7_-_48805181 0.47 ENSDART00000015884
mfge8a
milk fat globule-EGF factor 8 protein a
chr13_-_31452516 0.46 ENSDART00000193268
rtn1a
reticulon 1a
chr19_-_32487469 0.46 ENSDART00000050130
gmpr
guanosine monophosphate reductase
chr1_-_50859053 0.45 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr8_-_9570511 0.45 ENSDART00000044000
plxna3
plexin A3
chr23_-_15284757 0.45 ENSDART00000139135
sulf2b
sulfatase 2b
chr8_+_14792830 0.45 ENSDART00000139972
cacna1ea
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr5_+_43470544 0.44 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr4_-_1360495 0.44 ENSDART00000164623
ptn
pleiotrophin
chr2_-_16380283 0.43 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr8_+_51084993 0.42 ENSDART00000127709
ENSDART00000053768
DISP3
si:dkey-32e23.6
chr1_+_9708801 0.42 ENSDART00000189621
elfn1b
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr1_-_44704261 0.42 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr9_-_29844596 0.42 ENSDART00000138574
il1rapl1a
interleukin 1 receptor accessory protein-like 1a
chr20_-_25709247 0.41 ENSDART00000146711
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr18_-_42313798 0.40 ENSDART00000098639
cntn5
contactin 5
chr11_-_29650930 0.40 ENSDART00000166969
chd5
chromodomain helicase DNA binding protein 5
chr22_-_17574511 0.38 ENSDART00000181496
pip5k1ca
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr7_+_44484853 0.36 ENSDART00000189079
ENSDART00000121826
bean1
brain expressed, associated with NEDD4, 1
chr4_-_17629444 0.36 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr2_+_30787128 0.36 ENSDART00000189233
atp6v1h
ATPase H+ transporting V1 subunit H
chr24_-_10919588 0.36 ENSDART00000131204
asap1b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr17_+_23554932 0.35 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr5_-_55395964 0.35 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr5_+_36870737 0.35 ENSDART00000145182
slc8a2a
solute carrier family 8 (sodium/calcium exchanger), member 2a
chr18_-_1185772 0.34 ENSDART00000143245
nptnb
neuroplastin b
chr17_+_15534815 0.34 ENSDART00000159426
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr10_+_23060391 0.34 ENSDART00000079711
slc25a1a
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr6_-_49159207 0.34 ENSDART00000041942
tspan2a
tetraspanin 2a
chr19_-_5103313 0.33 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr25_-_1235457 0.33 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr17_-_45254585 0.32 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a
chr19_-_5805923 0.31 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr3_-_15889508 0.31 ENSDART00000148363
cramp1
cramped chromatin regulator homolog 1
chr8_+_43016714 0.30 ENSDART00000142671
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr5_+_20693724 0.30 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr18_-_14922872 0.29 ENSDART00000091722
panx2
pannexin 2
chr15_-_14486534 0.29 ENSDART00000179368
numbl
numb homolog (Drosophila)-like
chr18_+_16330025 0.29 ENSDART00000142353
nts
neurotensin
chr14_-_29859067 0.29 ENSDART00000136380
sorbs2b
sorbin and SH3 domain containing 2b
chr9_+_4306122 0.28 ENSDART00000193722
ENSDART00000190521
kalrna
kalirin RhoGEF kinase a
chr21_+_39432248 0.28 ENSDART00000179938
pafah1b1b
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr11_+_5842632 0.28 ENSDART00000111374
ENSDART00000158599
ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, (NADH-coenzyme Q reductase)
chr6_-_11523987 0.27 ENSDART00000189363
gulp1b
GULP, engulfment adaptor PTB domain containing 1b
chr22_+_18816662 0.27 ENSDART00000132476
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr3_-_42016693 0.26 ENSDART00000184741
ttyh3a
tweety family member 3a
chr19_+_19976990 0.26 ENSDART00000052627
npvf
neuropeptide VF precursor
chr3_-_26191960 0.26 ENSDART00000113843
ypel3
yippee-like 3
chr1_+_23783349 0.26 ENSDART00000007531
slit2
slit homolog 2 (Drosophila)
chr5_+_31860043 0.25 ENSDART00000036235
ENSDART00000140541
iscub
iron-sulfur cluster assembly enzyme b
chr6_+_40523370 0.25 ENSDART00000033819
prkcda
protein kinase C, delta a
chr6_-_45995401 0.25 ENSDART00000154392
ca16b
carbonic anhydrase XVI b
chr3_+_13637383 0.25 ENSDART00000166000
si:ch211-194b1.1
si:ch211-194b1.1
chr9_+_17982737 0.25 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr13_-_22907260 0.24 ENSDART00000143097
rufy2
RUN and FYVE domain containing 2
chr20_-_14680897 0.24 ENSDART00000063857
ENSDART00000161314
scrn2
secernin 2
chr3_+_32698424 0.24 ENSDART00000055340
fus
FUS RNA binding protein
chr12_+_28799988 0.24 ENSDART00000022724
pnpo
pyridoxamine 5'-phosphate oxidase
chr6_-_10320676 0.24 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr20_+_16750177 0.23 ENSDART00000185357
calm1b
calmodulin 1b
chr16_-_23885482 0.22 ENSDART00000132243
osgin2
oxidative stress induced growth inhibitor family member 2
chr15_-_11341635 0.22 ENSDART00000055220
rab30
RAB30, member RAS oncogene family
chr7_+_48805534 0.22 ENSDART00000145375
ENSDART00000148744
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr12_+_17439580 0.22 ENSDART00000189257
atad1b
ATPase family, AAA domain containing 1b
chr3_+_15360879 0.22 ENSDART00000083976
sh2b1
SH2B adaptor protein 1
chr1_+_31725154 0.22 ENSDART00000112333
ENSDART00000189801
cnnm2b
cyclin and CBS domain divalent metal cation transport mediator 2b
chr7_-_4036184 0.21 ENSDART00000019949
ndrg2
NDRG family member 2
chr3_-_45250924 0.21 ENSDART00000109017
usp31
ubiquitin specific peptidase 31
chr14_+_33525196 0.20 ENSDART00000085335
zdhhc9
zinc finger, DHHC-type containing 9
chr6_+_45692026 0.20 ENSDART00000164759
cntn4
contactin 4
chr22_+_30184039 0.20 ENSDART00000049075
add3a
adducin 3 (gamma) a
chr5_+_5689476 0.20 ENSDART00000022729
unm_sa808
un-named sa808
chr18_+_14529005 0.20 ENSDART00000186379
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chrM_+_3803 0.20 ENSDART00000093596
mt-nd1
NADH dehydrogenase 1, mitochondrial
chr17_+_23964132 0.20 ENSDART00000154823
xpo1b
exportin 1 (CRM1 homolog, yeast) b
chr24_+_29449690 0.20 ENSDART00000105743
ENSDART00000193556
ENSDART00000145816
ntng1a
netrin g1a
chr19_+_37620342 0.19 ENSDART00000158960
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr14_-_30490465 0.19 ENSDART00000173107
micu3b
mitochondrial calcium uptake family, member 3b
chr7_+_48805725 0.19 ENSDART00000166543
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr19_-_5103141 0.19 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr4_+_20954929 0.18 ENSDART00000143674
nav3
neuron navigator 3
chr10_-_25561751 0.18 ENSDART00000147089
grik1a
glutamate receptor, ionotropic, kainate 1a
chr6_+_51773873 0.18 ENSDART00000156516
tmem74b
transmembrane protein 74B
chr9_-_16877456 0.18 ENSDART00000161105
ENSDART00000160869
fbxl3a
F-box and leucine-rich repeat protein 3a
chr10_+_20128267 0.18 ENSDART00000064615
dmtn
dematin actin binding protein
chr1_+_54901028 0.18 ENSDART00000137352
zfyve27
zinc finger, FYVE domain containing 27
chr7_-_56180680 0.17 ENSDART00000098438
spg7
spastic paraplegia 7
chr17_-_7371564 0.17 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr15_+_5116179 0.17 ENSDART00000101937
pgm2l1
phosphoglucomutase 2-like 1
chr11_+_7432533 0.17 ENSDART00000180977
adgrl2a
adhesion G protein-coupled receptor L2a
chr18_+_9382847 0.17 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr16_+_21242491 0.17 ENSDART00000145886
osbpl3b
oxysterol binding protein-like 3b
chr18_-_29962234 0.16 ENSDART00000144996
si:ch73-103b9.2
si:ch73-103b9.2
chr13_-_29406534 0.16 ENSDART00000100877
zgc:153142
zgc:153142
chr6_-_15603675 0.16 ENSDART00000143502
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr16_+_12236339 0.16 ENSDART00000132468
tpi1b
triosephosphate isomerase 1b
chr11_+_24819324 0.16 ENSDART00000184549
kdm5ba
lysine (K)-specific demethylase 5Ba
chr10_-_26273629 0.16 ENSDART00000147790
dchs1b
dachsous cadherin-related 1b
chr21_+_44581654 0.15 ENSDART00000187201
ENSDART00000180360
ENSDART00000191543
ENSDART00000180039
ENSDART00000186308
TMEM164
transmembrane protein 164
chr15_+_31820536 0.15 ENSDART00000045921
frya
furry homolog a (Drosophila)
chr2_-_8688759 0.15 ENSDART00000010257
miga1
mitoguardin 1
chr17_+_30448452 0.14 ENSDART00000153939
lpin1
lipin 1
chr9_-_30502010 0.14 ENSDART00000149483
si:dkey-229b18.3
si:dkey-229b18.3
chr10_-_7988396 0.14 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr2_-_4797512 0.14 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr7_+_40884012 0.13 ENSDART00000149395
shha
sonic hedgehog a
chr7_-_30227878 0.13 ENSDART00000173514
znf710b
zinc finger protein 710b
chr11_+_24819624 0.13 ENSDART00000155514
kdm5ba
lysine (K)-specific demethylase 5Ba
chr16_-_45327616 0.13 ENSDART00000158733
si:dkey-33i11.1
si:dkey-33i11.1
chr6_+_3710865 0.12 ENSDART00000170781
phospho2
phosphatase, orphan 2
chr17_+_15535501 0.12 ENSDART00000002932
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr19_+_43669122 0.12 ENSDART00000139151
si:ch211-193k19.1
si:ch211-193k19.1
chr7_+_40083601 0.12 ENSDART00000099046
zgc:112356
zgc:112356
chr7_+_39079071 0.12 ENSDART00000181845
dgkza
diacylglycerol kinase, zeta a
chr11_+_19068442 0.12 ENSDART00000171766
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr15_+_1705167 0.12 ENSDART00000081940
otol1b
otolin 1b
chr16_+_27349585 0.12 ENSDART00000142573
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr3_-_25148047 0.12 ENSDART00000089325
mief1
mitochondrial elongation factor 1
chr9_-_30808073 0.12 ENSDART00000146300
klf5b
Kruppel-like factor 5b
chr6_-_12788539 0.12 ENSDART00000156415
dock9b
dedicator of cytokinesis 9b
chr5_+_1219187 0.11 ENSDART00000129490
gb:bc139872
expressed sequence BC139872
chr9_-_43213229 0.11 ENSDART00000139775
sestd1
SEC14 and spectrin domains 1
chr8_+_42917515 0.11 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr2_+_2168547 0.11 ENSDART00000029347
higd1a
HIG1 hypoxia inducible domain family, member 1A
chr14_+_9583588 0.11 ENSDART00000164101
tmem129
transmembrane protein 129, E3 ubiquitin protein ligase
chr22_-_834106 0.11 ENSDART00000105873
cry4
cryptochrome circadian clock 4
chr8_+_8012570 0.10 ENSDART00000183429
si:ch211-169p10.1
si:ch211-169p10.1
chr8_+_25893071 0.10 ENSDART00000078161
tmem115
transmembrane protein 115
chr21_+_15709061 0.10 ENSDART00000065772
ddt
D-dopachrome tautomerase
chr18_-_12451772 0.10 ENSDART00000175083
si:ch211-1e14.1
si:ch211-1e14.1
chr23_+_42813415 0.10 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr11_+_24900123 0.10 ENSDART00000044987
ENSDART00000148023
timm17a
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr18_+_39327010 0.10 ENSDART00000012164
tmod2
tropomodulin 2
chr13_+_31172833 0.09 ENSDART00000176378
CR931802.3

chr12_+_46708920 0.09 ENSDART00000153089
exoc7
exocyst complex component 7
chr8_+_25902170 0.09 ENSDART00000193130
rhoab
ras homolog gene family, member Ab
chr5_-_29780752 0.09 ENSDART00000137400
ENSDART00000145021
cfap77
cilia and flagella associated protein 77
chr5_+_41322783 0.08 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr11_+_30729745 0.08 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr19_-_3574060 0.08 ENSDART00000105120
tmem170b
transmembrane protein 170B
chr14_+_2095394 0.08 ENSDART00000186847
CT573264.2

chr1_+_39859782 0.08 ENSDART00000149984
irf2a
interferon regulatory factor 2a
chr24_+_39186940 0.07 ENSDART00000155817
spsb3b
splA/ryanodine receptor domain and SOCS box containing 3b
chr3_+_24060454 0.07 ENSDART00000143088
cbx1a
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr17_+_2214283 0.07 ENSDART00000189187
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr25_+_34749812 0.07 ENSDART00000185712
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr19_+_20724347 0.07 ENSDART00000090757
kat2b
K(lysine) acetyltransferase 2B
chr7_+_38265363 0.06 ENSDART00000009386
gpatch1
G patch domain containing 1
chr25_-_31396479 0.06 ENSDART00000156828
prr33
proline rich 33
chr22_+_11153590 0.06 ENSDART00000188207
bcor
BCL6 corepressor
chr16_-_35427060 0.06 ENSDART00000172294
ctps1b
CTP synthase 1b
chr10_+_20113830 0.05 ENSDART00000139722
dmtn
dematin actin binding protein
chr18_+_36066389 0.05 ENSDART00000059347
bckdha
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr12_+_7399403 0.05 ENSDART00000103526
bicc1b
BicC family RNA binding protein 1b
chr10_+_17592273 0.05 ENSDART00000141221
KCNN2
si:dkey-76p7.5
chr21_-_30031396 0.05 ENSDART00000157167
pwwp2a
PWWP domain containing 2A
chr14_-_29858883 0.05 ENSDART00000141034
sorbs2b
sorbin and SH3 domain containing 2b
chr13_+_15800742 0.05 ENSDART00000146234
apopt1
apoptogenic 1, mitochondrial
chr17_-_8673567 0.05 ENSDART00000192714
ENSDART00000012546
ctbp2a
C-terminal binding protein 2a
chr8_+_21225064 0.05 ENSDART00000129210
cry1ba
cryptochrome circadian clock 1ba
chr5_-_35456269 0.04 ENSDART00000051312
ttc33
tetratricopeptide repeat domain 33
chr17_-_7818944 0.04 ENSDART00000135538
ENSDART00000037541
rmnd1
required for meiotic nuclear division 1 homolog
chr7_+_22313533 0.04 ENSDART00000123457
TMEM102
si:dkey-11f12.2
chr7_+_22705656 0.04 ENSDART00000193008
si:dkey-165a24.9
si:dkey-165a24.9
chr17_-_8673278 0.03 ENSDART00000171850
ENSDART00000017337
ENSDART00000148504
ENSDART00000148808
ctbp2a
C-terminal binding protein 2a
chr1_+_27977297 0.03 ENSDART00000180692
ENSDART00000166819
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr15_-_25304710 0.03 ENSDART00000190690
pafah1b1a
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a
chr20_-_31018569 0.03 ENSDART00000136039
fndc1
fibronectin type III domain containing 1
chr9_-_43213057 0.03 ENSDART00000059448
ENSDART00000133589
sestd1
SEC14 and spectrin domains 1
chr13_-_18195942 0.03 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16

Network of associatons between targets according to the STRING database.

First level regulatory network of roraa+rorab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.6 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.5 GO:0021767 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.3 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.3 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.2 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.1 0.3 GO:0045938 regulation of endocrine process(GO:0044060) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) endocrine hormone secretion(GO:0060986)
0.1 0.5 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.2 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 0.4 GO:0048069 eye pigmentation(GO:0048069)
0.0 1.0 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.5 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.8 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.7 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.6 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.5 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.7 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.1 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.2 GO:0072576 liver morphogenesis(GO:0072576)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0071376 neutrophil homeostasis(GO:0001780) response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.7 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0032438 melanosome organization(GO:0032438)
0.0 0.0 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.7 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.6 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0097268 cytoophidium(GO:0097268)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 1.0 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 0.5 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.4 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.4 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE