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PRJNA207719: Tissue specific transcriptome profiling

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Results for runx2a+runx2b

Z-value: 1.28

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Transcription factors associated with runx2a+runx2b

Gene Symbol Gene ID Gene Info
runx2a
ENSDARG00000040261 RUNX family transcription factor 2a
runx2b
ENSDARG00000059233 RUNX family transcription factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx2bdr11_v1_chr20_-_44055095_440551230.866.3e-02Click!
runx2adr11_v1_chr17_+_5351922_53519220.296.4e-01Click!

Activity profile of runx2a+runx2b motif

Sorted Z-values of runx2a+runx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_23277939 1.43 ENSDART00000003514
plp1b
proteolipid protein 1b
chr19_+_30633453 1.30 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr24_-_4973765 1.15 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr5_-_23277385 0.94 ENSDART00000134982
plp1b
proteolipid protein 1b
chr7_+_25858380 0.90 ENSDART00000148780
ENSDART00000079218
mtmr1a
myotubularin related protein 1a
chr2_-_44282796 0.89 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr2_-_44283554 0.89 ENSDART00000184684
mpz
myelin protein zero
chr7_+_46368520 0.84 ENSDART00000192821
znf536
zinc finger protein 536
chr13_+_27316632 0.84 ENSDART00000016121
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr23_-_15878879 0.84 ENSDART00000010119
eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr13_+_27316934 0.83 ENSDART00000164533
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr19_-_9867001 0.77 ENSDART00000091695
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr15_+_29088426 0.71 ENSDART00000187290
si:ch211-137a8.4
si:ch211-137a8.4
chr15_+_39977461 0.70 ENSDART00000063786
cab39
calcium binding protein 39
chr1_+_15137901 0.69 ENSDART00000111475
pcdh7a
protocadherin 7a
chr25_+_34984333 0.65 ENSDART00000154760
ccdc136b
coiled-coil domain containing 136b
chr15_+_19544052 0.62 ENSDART00000062560
zgc:77784
zgc:77784
chr21_+_7582036 0.61 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr22_-_33679277 0.61 ENSDART00000169948
FO904977.1

chr8_+_14778292 0.61 ENSDART00000089971
cacna1ea
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr9_+_38883388 0.60 ENSDART00000135902
map2
microtubule-associated protein 2
chr7_-_33829824 0.60 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr2_-_44280061 0.60 ENSDART00000136818
mpz
myelin protein zero
chr8_+_36803415 0.60 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr2_+_22694382 0.58 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr5_-_6377865 0.56 ENSDART00000031775
zgc:73226
zgc:73226
chr16_+_31853919 0.56 ENSDART00000133886
atn1
atrophin 1
chr20_+_5564042 0.55 ENSDART00000090934
ENSDART00000127050
nrxn3b
neurexin 3b
chr1_+_49266886 0.55 ENSDART00000137179
caly
calcyon neuron-specific vesicular protein
chr15_-_12545683 0.55 ENSDART00000162807
scn2b
sodium channel, voltage-gated, type II, beta
chr9_+_42066030 0.55 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr17_+_26815021 0.54 ENSDART00000086885
asmt2
acetylserotonin O-methyltransferase 2
chr5_+_44190974 0.54 ENSDART00000182634
ENSDART00000190626
TMEM8B
si:dkey-84j12.1
chr19_+_16222618 0.54 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
ptprua
protein tyrosine phosphatase, receptor type, U, a
chr3_-_22212764 0.53 ENSDART00000155490
maptb
microtubule-associated protein tau b
chr7_-_38633867 0.53 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr9_+_38888025 0.52 ENSDART00000148306
map2
microtubule-associated protein 2
chr7_-_12065668 0.52 ENSDART00000101537
mex3b
mex-3 RNA binding family member B
chr8_+_25173317 0.50 ENSDART00000142006
gpr61
G protein-coupled receptor 61
chr13_+_7292061 0.50 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr16_+_50741154 0.49 ENSDART00000101627
IGLON5
zgc:110372
chr1_+_41854298 0.48 ENSDART00000192672
smox
spermine oxidase
chr14_-_46616487 0.47 ENSDART00000105417
ENSDART00000166550
ENSDART00000105418
prom1a
prominin 1a
chr22_+_20195280 0.47 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
si:dkey-110c1.7
chr7_+_23515966 0.47 ENSDART00000186893
ENSDART00000186189
zgc:109889
zgc:109889
chr4_+_41602 0.47 ENSDART00000159640
phtf2
putative homeodomain transcription factor 2
chr4_+_17336557 0.46 ENSDART00000111650
pmch
pro-melanin-concentrating hormone
chr4_-_2525916 0.46 ENSDART00000134123
ENSDART00000132581
ENSDART00000019508
csrp2
cysteine and glycine-rich protein 2
chr19_+_37857936 0.46 ENSDART00000189289
nxph1
neurexophilin 1
chr2_-_31936966 0.45 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amph
amphiphysin
chr6_+_13933464 0.45 ENSDART00000109144
ptprnb
protein tyrosine phosphatase, receptor type, Nb
chr3_+_54168007 0.45 ENSDART00000109894
olfm2a
olfactomedin 2a
chr23_-_36724575 0.44 ENSDART00000159560
agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr4_+_20255160 0.44 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr20_+_38725662 0.43 ENSDART00000181873
uts1
urotensin 1
chr10_-_17103651 0.43 ENSDART00000108959
RNF208
ring finger protein 208
chr6_+_38381957 0.43 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr4_+_11375894 0.43 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr10_+_21797276 0.43 ENSDART00000169105
pcdh1g29
protocadherin 1 gamma 29
chr7_+_38770167 0.42 ENSDART00000190827
arhgap1
Rho GTPase activating protein 1
chr5_-_28606916 0.42 ENSDART00000026107
ENSDART00000137717
tnc
tenascin C
chr3_+_28576173 0.42 ENSDART00000151189
sept12
septin 12
chr10_+_19338255 0.42 ENSDART00000113737
lrrtm4l1
leucine rich repeat transmembrane neuronal 4 like 1
chr21_-_21096437 0.42 ENSDART00000186552
ank1b
ankyrin 1, erythrocytic b
chr13_-_23095006 0.42 ENSDART00000089242
kif1bp
kif1 binding protein
chr3_+_15271943 0.42 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr21_-_42100471 0.42 ENSDART00000166148
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_-_8428736 0.42 ENSDART00000138435
ENSDART00000121823
syngr3b
synaptogyrin 3b
chr13_+_35856463 0.41 ENSDART00000171056
ENSDART00000017202
kcnk1b
potassium channel, subfamily K, member 1b
chr18_+_18612388 0.41 ENSDART00000186455
st3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr15_-_45538773 0.41 ENSDART00000113494
MB21D2
Mab-21 domain containing 2
chr17_-_46457622 0.41 ENSDART00000130215
TMEM179 (1 of many)
transmembrane protein 179
chr17_+_13031497 0.41 ENSDART00000115208
fbxo33
F-box protein 33
chr13_-_51247529 0.40 ENSDART00000191774
ENSDART00000083788
AL929217.1

chr2_-_50298337 0.40 ENSDART00000155125
cntnap2b
contactin associated protein like 2b
chr8_-_17067364 0.40 ENSDART00000132687
rab3c
RAB3C, member RAS oncogene family
chr4_-_8882572 0.40 ENSDART00000190060
mpped1
metallophosphoesterase domain containing 1
chr24_-_31843173 0.40 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr11_+_24994705 0.39 ENSDART00000129211
zgc:92107
zgc:92107
chr7_-_72605673 0.39 ENSDART00000123887
MAPK8IP1 (1 of many)
mitogen-activated protein kinase 8 interacting protein 1
chr9_+_17984358 0.39 ENSDART00000192399
akap11
A kinase (PRKA) anchor protein 11
chr5_-_32445835 0.39 ENSDART00000170919
ncs1a
neuronal calcium sensor 1a
chr23_-_637347 0.39 ENSDART00000132175
l1camb
L1 cell adhesion molecule, paralog b
chr19_-_3482138 0.38 ENSDART00000168139
hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr2_-_22286828 0.38 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr11_-_44999858 0.38 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr9_+_7909490 0.38 ENSDART00000133063
ENSDART00000109288
myo16
myosin XVI
chr21_+_21201346 0.38 ENSDART00000142961
rictorb
RPTOR independent companion of MTOR, complex 2b
chr3_+_15773991 0.37 ENSDART00000089923
znf652
zinc finger protein 652
chr3_-_28428198 0.37 ENSDART00000151546
rbfox1
RNA binding fox-1 homolog 1
chr3_-_36440705 0.37 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr3_+_14339728 0.36 ENSDART00000184127
plppr2a
phospholipid phosphatase related 2a
chr13_+_11440389 0.36 ENSDART00000186463
zbtb18
zinc finger and BTB domain containing 18
chr3_+_29600917 0.36 ENSDART00000048867
sstr3
somatostatin receptor 3
chr16_+_11483811 0.36 ENSDART00000169012
ENSDART00000173042
grik5
glutamate receptor, ionotropic, kainate 5
chr20_-_30035326 0.35 ENSDART00000141068
sox11b
SRY (sex determining region Y)-box 11b
chr10_-_7974155 0.35 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr24_-_24848612 0.35 ENSDART00000190941
crhb
corticotropin releasing hormone b
chr7_-_40993456 0.35 ENSDART00000031700
en2a
engrailed homeobox 2a
chr14_-_14746767 0.35 ENSDART00000183755
ENSDART00000190938
ogt.1
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr23_+_27789795 0.34 ENSDART00000141458
kmt2d
lysine (K)-specific methyltransferase 2D
chr2_+_24722771 0.34 ENSDART00000147207
pik3r2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr16_-_32672883 0.34 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
pnisr
PNN-interacting serine/arginine-rich protein
chr23_+_28582865 0.34 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr15_-_24869826 0.34 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr6_+_13806466 0.34 ENSDART00000043522
tmem198b
transmembrane protein 198b
chr21_-_35324091 0.33 ENSDART00000185042
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr11_-_27057572 0.33 ENSDART00000043091
iqsec1b
IQ motif and Sec7 domain 1b
chr8_-_50888806 0.33 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr18_+_45573416 0.33 ENSDART00000132184
ENSDART00000145288
kifc3
kinesin family member C3
chr2_-_40135942 0.33 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
epha4a
eph receptor A4a
chr13_+_40019001 0.33 ENSDART00000158820
golga7bb
golgin A7 family, member Bb
chr15_-_34213898 0.33 ENSDART00000191945
ENSDART00000186089
etv1
ets variant 1
chr25_+_19954576 0.33 ENSDART00000149335
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr15_-_34214440 0.33 ENSDART00000167052
etv1
ets variant 1
chr13_-_10261383 0.32 ENSDART00000080808
six3a
SIX homeobox 3a
chr9_-_37749973 0.32 ENSDART00000087663
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr6_-_16394528 0.32 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr5_-_2752573 0.32 ENSDART00000168121
lzts3a
leucine zipper, putative tumor suppressor family member 3a
chr16_-_9869056 0.32 ENSDART00000149312
ncalda
neurocalcin delta a
chr25_+_21324588 0.31 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr19_+_42693855 0.31 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr10_+_10738880 0.31 ENSDART00000004181
slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr5_-_38342992 0.31 ENSDART00000140337
mink1
misshapen-like kinase 1
chr12_+_32159272 0.31 ENSDART00000153167
hlfb
hepatic leukemia factor b
chr17_-_200316 0.31 ENSDART00000190561
CABZ01083778.1

chr1_+_10018466 0.31 ENSDART00000113551
trim2b
tripartite motif containing 2b
chr3_+_37197686 0.30 ENSDART00000151144
fmnl1a
formin-like 1a
chr19_+_5146460 0.30 ENSDART00000150740
si:dkey-89b17.4
si:dkey-89b17.4
chr7_+_72882446 0.30 ENSDART00000131113
ENSDART00000174223
ADGRL3
adhesion G protein-coupled receptor L3
chr12_+_18543783 0.30 ENSDART00000148326
ENSDART00000134530
mlst8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr4_+_3980247 0.30 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr5_-_52277643 0.30 ENSDART00000010757
rgmb
repulsive guidance molecule family member b
chr9_-_28867562 0.30 ENSDART00000189597
ENSDART00000060321
zgc:91818
zgc:91818
chr1_+_6817292 0.30 ENSDART00000145822
ENSDART00000092118
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr3_-_1204341 0.30 ENSDART00000089646
fam234b
family with sequence similarity 234, member B
chr6_+_23810529 0.30 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr6_-_10305918 0.29 ENSDART00000090994
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr25_-_7925269 0.29 ENSDART00000014274
glcea
glucuronic acid epimerase a
chr25_+_20119466 0.29 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr4_-_9533345 0.29 ENSDART00000128501
si:ch73-139j3.4
si:ch73-139j3.4
chr15_+_46108548 0.29 ENSDART00000099023
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr24_+_37080771 0.29 ENSDART00000159942
kcnc3b
potassium voltage-gated channel, Shaw-related subfamily, member 3b
chr6_+_55357188 0.29 ENSDART00000158219
pltp
phospholipid transfer protein
chr16_-_21591533 0.29 ENSDART00000159870
ddr1
discoidin domain receptor tyrosine kinase 1
chr18_-_21267103 0.29 ENSDART00000136285
pnp6
purine nucleoside phosphorylase 6
chr20_-_31781941 0.29 ENSDART00000139417
stxbp5a
syntaxin binding protein 5a (tomosyn)
chr6_+_29860776 0.28 ENSDART00000028406
dlg1
discs, large homolog 1 (Drosophila)
chr5_+_61657702 0.28 ENSDART00000134387
ENSDART00000171248
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr23_+_26979174 0.28 ENSDART00000018654
rnd1b
Rho family GTPase 1b
chr8_+_8735285 0.28 ENSDART00000165655
elk1
ELK1, member of ETS oncogene family
chr25_-_32449235 0.28 ENSDART00000115343
atp8b4
ATPase phospholipid transporting 8B4
chr25_-_7925019 0.28 ENSDART00000183309
glcea
glucuronic acid epimerase a
chr2_+_31948352 0.28 ENSDART00000192611
ankhb
ANKH inorganic pyrophosphate transport regulator b
chr13_-_29424454 0.28 ENSDART00000026765
slc18a3a
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr6_-_12314475 0.28 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr7_+_31051603 0.27 ENSDART00000108721
tjp1a
tight junction protein 1a
chr14_-_2163454 0.27 ENSDART00000160123
ENSDART00000169653
pcdh2ab9
pcdh2ac
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr3_-_37476278 0.27 ENSDART00000083442
si:ch211-278a6.1
si:ch211-278a6.1
chr1_-_55810730 0.27 ENSDART00000100551
zgc:136908
zgc:136908
chr15_+_6117502 0.27 ENSDART00000188293
PCP4 (1 of many)
Purkinje cell protein 4
chr7_+_63325819 0.27 ENSDART00000085612
ENSDART00000161436
pcdh7b
protocadherin 7b
chr10_+_26515946 0.27 ENSDART00000134276
synj1
synaptojanin 1
chr18_+_45573251 0.26 ENSDART00000191309
kifc3
kinesin family member C3
chr5_+_62374092 0.26 ENSDART00000082965
CU928117.1

chr9_-_46842179 0.26 ENSDART00000054137
igfbp5b
insulin-like growth factor binding protein 5b
chr3_+_36160979 0.26 ENSDART00000038525
si:ch211-234h8.7
si:ch211-234h8.7
chr7_-_18598661 0.26 ENSDART00000182109
DTX4
si:ch211-119e14.2
chr8_+_13849999 0.26 ENSDART00000143784
doc2d
double C2-like domains, delta
chr15_+_17446796 0.26 ENSDART00000157189
snx19b
sorting nexin 19b
chr25_+_31929325 0.26 ENSDART00000181095
apba2a
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr11_+_37144328 0.26 ENSDART00000162830
wnk2
WNK lysine deficient protein kinase 2
chr15_+_37197494 0.26 ENSDART00000166203
aplp1
amyloid beta (A4) precursor-like protein 1
chr15_-_35252522 0.25 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr14_+_24845941 0.25 ENSDART00000187513
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr23_-_7799184 0.25 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr9_+_35860975 0.25 ENSDART00000134447
rcan1a
regulator of calcineurin 1a
chr1_+_2101541 0.25 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
mbnl2
muscleblind-like splicing regulator 2
chr8_-_39859688 0.25 ENSDART00000019907
unc119.1
unc-119 homolog 1
chr19_-_5812319 0.25 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr17_+_691453 0.25 ENSDART00000159271
fancm
Fanconi anemia, complementation group M
chr2_-_42871286 0.25 ENSDART00000087823
adcy8
adenylate cyclase 8 (brain)
chr16_-_22863348 0.25 ENSDART00000147609
shc1
SHC (Src homology 2 domain containing) transforming protein 1
chr4_-_15420452 0.25 ENSDART00000016230
plxna4
plexin A4
chr21_+_34992550 0.25 ENSDART00000109041
ENSDART00000135400
tmprss15
transmembrane protease, serine 15
chr23_-_27822920 0.25 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr15_+_42767803 0.25 ENSDART00000164879
slc8a2b
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr18_-_40508528 0.24 ENSDART00000185249
chrna5
cholinergic receptor, nicotinic, alpha 5
chr10_+_21796477 0.24 ENSDART00000176255
pcdh1g29
protocadherin 1 gamma 29
chr8_+_26432677 0.24 ENSDART00000078369
ENSDART00000131925
zgc:136971
zgc:136971
chr24_-_18877118 0.24 ENSDART00000092783
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr5_+_23597144 0.24 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
kat5b
K(lysine) acetyltransferase 5b
chr21_+_33503835 0.24 ENSDART00000125658
clint1b
clathrin interactor 1b
chr23_-_29376859 0.24 ENSDART00000146411
sst6
somatostatin 6
chr13_+_17468161 0.23 ENSDART00000008906
znf503
zinc finger protein 503
chr8_+_29856013 0.23 ENSDART00000061981
ENSDART00000149610
hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
chr24_-_10919588 0.23 ENSDART00000131204
asap1b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr12_-_48992527 0.23 ENSDART00000169696
CDHR1 (1 of many)
cadherin related family member 1
chr20_+_18225329 0.23 ENSDART00000144172
kctd1
potassium channel tetramerization domain containing 1
chr18_-_41375120 0.23 ENSDART00000098673
ptx3a
pentraxin 3, long a

Network of associatons between targets according to the STRING database.

First level regulatory network of runx2a+runx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.6 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.2 0.5 GO:0030186 melatonin metabolic process(GO:0030186)
0.2 1.2 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 2.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.3 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.6 GO:0021767 mammillary body development(GO:0021767)
0.1 0.4 GO:0015677 copper ion import(GO:0015677)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.3 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.5 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.3 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.2 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.1 0.7 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.3 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.1 GO:0002837 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.2 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.3 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.2 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 1.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.5 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519) spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0001709 cell fate determination(GO:0001709)
0.0 1.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.3 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.2 GO:0046661 male sex differentiation(GO:0046661)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0048389 intermediate mesoderm development(GO:0048389)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.2 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.6 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 1.1 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.6 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 GO:0043209 myelin sheath(GO:0043209)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.5 GO:0071914 prominosome(GO:0071914)
0.1 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925) basal part of cell(GO:0045178)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.6 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 0.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.5 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.3 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.3 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.4 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0033745 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions