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PRJNA207719: Tissue specific transcriptome profiling

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Results for rxraa+rxrab+rxrba+rxrgb

Z-value: 1.10

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Transcription factors associated with rxraa+rxrab+rxrba+rxrgb

Gene Symbol Gene ID Gene Info
ENSDARG00000004697 retinoid X receptor, gamma b
ENSDARG00000035127 retinoid x receptor, alpha b
ENSDARG00000057737 retinoid X receptor, alpha a
ENSDARG00000078954 retinoid x receptor, beta a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rxrabdr11_v1_chr5_-_64511428_64511428-0.884.6e-02Click!
rxrgbdr11_v1_chr20_+_33875256_338752560.838.2e-02Click!
rxraadr11_v1_chr21_+_17880511_17880511-0.838.5e-02Click!
rxrbadr11_v1_chr19_-_7272921_7273057-0.828.6e-02Click!

Activity profile of rxraa+rxrab+rxrba+rxrgb motif

Sorted Z-values of rxraa+rxrab+rxrba+rxrgb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_34297271 0.91 ENSDART00000180342
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr23_-_45705525 0.88 ENSDART00000148959
endothelin receptor type Ab
chr7_+_34296789 0.85 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr21_-_19006631 0.84 ENSDART00000080269
ENSDART00000191682
phosphoglycerate mutase 2 (muscle)
chr12_-_6033824 0.83 ENSDART00000131301
ENSDART00000139419
ENSDART00000032050
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 1
chr11_+_18037729 0.80 ENSDART00000111624
zgc:175135
chr11_+_18053333 0.78 ENSDART00000075750
zgc:175135
chr13_+_50375800 0.74 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr22_+_38229321 0.73 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
chr7_-_52096498 0.72 ENSDART00000098688
ENSDART00000098690
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr17_+_450956 0.70 ENSDART00000183022
ENSDART00000171386
zgc:194887
chr2_-_24289641 0.68 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myosin heavy chain 7-like
chr21_+_20771082 0.66 ENSDART00000079732
3-oxoacid CoA transferase 1b
chr11_+_11201096 0.66 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr2_+_22659787 0.66 ENSDART00000043956
zgc:161973
chr2_-_39017838 0.65 ENSDART00000048838
retinol binding protein 2b, cellular
chr2_-_57076687 0.65 ENSDART00000161523
solute carrier family 25, member 42
chr17_+_30450163 0.64 ENSDART00000104257
lipin 1
chr6_+_60055168 0.62 ENSDART00000008752
phosphoenolpyruvate carboxykinase 1 (soluble)
chr19_-_41213718 0.60 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr7_+_69019851 0.60 ENSDART00000162891

chr7_-_51953613 0.59 ENSDART00000142042
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr6_-_59563597 0.59 ENSDART00000166311
inhibin beta E subunit
chr22_-_23612854 0.58 ENSDART00000165885
complement factor H like 5
chr20_+_47953047 0.56 ENSDART00000079734
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr9_-_43082945 0.55 ENSDART00000142257
coiled-coil domain containing 141
chr18_-_17415580 0.54 ENSDART00000150077
ENSDART00000100190
carboxylesterase 2 (intestine, liver)
chr17_-_32370047 0.51 ENSDART00000145487
Kruppel-like factor 11b
chr11_+_18157260 0.51 ENSDART00000144659
zgc:173545
chr7_-_52096287 0.51 ENSDART00000174068
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr7_+_31838320 0.50 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
myosin binding protein C, cardiac
chr11_+_18130300 0.50 ENSDART00000169146
zgc:175135
chr22_-_20126230 0.48 ENSDART00000138688
cAMP responsive element binding protein 3-like 3a
chr20_-_24443680 0.48 ENSDART00000191337

chr7_+_31871830 0.47 ENSDART00000139899
myosin binding protein C, cardiac
chr20_+_54304800 0.47 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr3_+_12744083 0.46 ENSDART00000158554
ENSDART00000169545
cytochrome P450, family 2, subfamily k, polypeptide 21
chr23_+_42434348 0.46 ENSDART00000161027
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr6_+_154556 0.46 ENSDART00000193153
zinc finger, GATA-like protein 1
chr13_+_829585 0.46 ENSDART00000029051
glutathione S-transferase, alpha tandem duplicate 2
chr13_+_41819817 0.45 ENSDART00000185778

chr22_-_38274188 0.45 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr11_-_22303678 0.45 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr7_-_51953807 0.45 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr6_+_60036767 0.44 ENSDART00000155009
transglutaminase 8
chr12_-_47774807 0.43 ENSDART00000193831

chr6_+_43353271 0.42 ENSDART00000191775

chr20_+_54309148 0.42 ENSDART00000099360
zona pellucida glycoprotein 2, tandem duplicate 1
chr19_+_46113828 0.42 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr20_+_54295213 0.42 ENSDART00000074085
zona pellucida glycoprotein 2, tandem duplicate 3
chr6_+_153146 0.41 ENSDART00000097468
zinc finger, GATA-like protein 1
chr21_-_1640547 0.41 ENSDART00000151041
zgc:152948
chr8_+_40284973 0.41 ENSDART00000018401
ORAI calcium release-activated calcium modulator 1a
chr20_+_54312970 0.41 ENSDART00000024598
ENSDART00000193172
zona pellucida glycoprotein 2, tandem duplicate 5
chr5_-_36837846 0.41 ENSDART00000032481
creatine kinase, muscle a
chr11_+_24313931 0.40 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr20_+_54299419 0.40 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr20_+_572037 0.40 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
SET and MYND domain containing 2b
chr22_-_7050 0.39 ENSDART00000127829
ATPase family, AAA domain containing 3
chr2_+_52847049 0.39 ENSDART00000121980
cAMP responsive element binding protein 3-like 3b
chr22_-_15587360 0.38 ENSDART00000142717
ENSDART00000138978
tropomyosin 4a
chr7_-_24046999 0.38 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dehydrogenase/reductase (SDR family) member 4
chr5_-_69940868 0.38 ENSDART00000185924
ENSDART00000097357
UDP glucuronosyltransferase 2 family, polypeptide A4
chr13_-_34683370 0.37 ENSDART00000113661
kinesin family member 16Bb
chr17_+_53297822 0.37 ENSDART00000168297
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr23_-_44903048 0.37 ENSDART00000149103
FH2 domain containing 5
chr25_+_36347126 0.37 ENSDART00000152449
si:ch211-113a14.22
chr7_-_2090594 0.37 ENSDART00000183166
si:cabz01007802.1
chr19_+_40861853 0.36 ENSDART00000126470
zgc:85777
chr23_-_12788113 0.36 ENSDART00000103231
ENSDART00000146640
ENSDART00000180549
si:dkey-96f10.1
chr21_-_30166097 0.36 ENSDART00000130676
heparin-binding EGF-like growth factor b
chr11_+_18175893 0.35 ENSDART00000177625
zgc:173545
chr22_-_5171362 0.35 ENSDART00000124889
tumor necrosis factor, alpha-induced protein 8-like 1
chr21_+_25777425 0.35 ENSDART00000021620
claudin d
chr20_+_15015557 0.35 ENSDART00000039345
myocilin
chr8_+_48491387 0.35 ENSDART00000086053
si:ch211-263k4.2
chr3_+_12732382 0.35 ENSDART00000158403
cytochrome P450, family 2, subfamily k, polypeptide 19
chr5_-_36549024 0.35 ENSDART00000097671
zgc:158432
chr20_-_25522911 0.34 ENSDART00000063058
cytochrome P450, family 2, subfamily N, polypeptide 13
chr2_-_14793343 0.33 ENSDART00000132264
si:ch73-366i20.1
chr19_+_32166702 0.33 ENSDART00000021798
fatty acid binding protein 11a
chr14_-_48103207 0.33 ENSDART00000056712
electron-transferring-flavoprotein dehydrogenase
chr2_+_42191592 0.32 ENSDART00000144716
caveolae associated protein 4a
chr20_-_48604621 0.32 ENSDART00000161769
ENSDART00000157871
microsomal glutathione S-transferase 3a
chr6_+_1787160 0.32 ENSDART00000113505
myosin, light chain 9b, regulatory
chr6_-_7082108 0.32 ENSDART00000081760
Indian hedgehog homolog b
chr16_-_23800484 0.32 ENSDART00000139964
ribosomal protein S27, isoform 2
chr8_-_2529878 0.31 ENSDART00000056767
acetyl-CoA acyltransferase 2
chr3_+_12718100 0.31 ENSDART00000162343
ENSDART00000192425
cytochrome P450, family 2, subfamily k, polypeptide 20
chr2_+_3823813 0.31 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
Niemann-Pick disease, type C1
chr23_-_23179417 0.31 ENSDART00000122945
ENSDART00000091662
NOC2-like nucleolar associated transcriptional repressor
chr9_+_35077546 0.31 ENSDART00000142688
si:dkey-192g7.3
chr3_-_18805225 0.31 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr15_+_26603395 0.31 ENSDART00000188667
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr17_-_12408109 0.30 ENSDART00000155509
ankyrin repeat and EF-hand domain containing 1b
chr14_+_30340251 0.30 ENSDART00000148448
microtubule associated tumor suppressor 1a
chr20_-_48604199 0.30 ENSDART00000161762
ENSDART00000170894
microsomal glutathione S-transferase 3a
chr12_-_5120175 0.29 ENSDART00000160729
retinol binding protein 4, plasma
chr23_-_16737161 0.28 ENSDART00000132573
si:ch211-224l10.4
chr22_-_14262115 0.28 ENSDART00000168264
si:ch211-246m6.5
chr5_-_41875834 0.28 ENSDART00000133592
si:dkey-65b12.10
chr12_-_34580988 0.28 ENSDART00000152926
BAH domain and coiled-coil containing 1b
chr14_-_46238186 0.28 ENSDART00000173245
si:ch211-113d11.6
chr13_+_844150 0.27 ENSDART00000058260
glutathione S-transferase, alpha tandem duplicate 1
chr24_-_26820698 0.27 ENSDART00000147788
fibronectin type III domain containing 3Bb
chr6_-_28117995 0.27 ENSDART00000147253
si:ch73-194h10.3
chr1_-_49505449 0.27 ENSDART00000187294
ENSDART00000132171
si:dkeyp-80c12.5
chr10_-_690072 0.27 ENSDART00000164871
ENSDART00000142833
GLIS family zinc finger 3
chr15_+_28268135 0.27 ENSDART00000152536
ENSDART00000188550
myosin Ic, paralog b
chr22_+_9039620 0.27 ENSDART00000188929
si:ch211-213a13.2
chr24_-_11446156 0.26 ENSDART00000143921
ENSDART00000066778
acyl-CoA dehydrogenase family, member 11
chr3_-_34561624 0.26 ENSDART00000129313
septin 9a
chr21_+_15704556 0.26 ENSDART00000024858
ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr20_-_14114078 0.26 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr5_-_1962500 0.26 ENSDART00000150163
ribosomal protein, large, P0
chr20_-_47953524 0.26 ENSDART00000167986
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr3_+_16922226 0.26 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr15_-_6946286 0.26 ENSDART00000019330
enoyl CoA hydratase 1, peroxisomal
chr12_-_36268723 0.26 ENSDART00000113740
potassium inwardly-rectifying channel, subfamily J, member 16
chr12_-_5120339 0.26 ENSDART00000168759
retinol binding protein 4, plasma
chr17_-_12196865 0.26 ENSDART00000154694
kinesin family member 28
chr9_-_22834860 0.25 ENSDART00000146486
nebulin
chr20_+_35445462 0.25 ENSDART00000124497
tudor domain containing 6
chr18_+_17611627 0.25 ENSDART00000046891
cholesteryl ester transfer protein, plasma
chr8_+_11687254 0.25 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr8_+_39802506 0.25 ENSDART00000018862
HNF1 homeobox a
chr2_+_57801960 0.25 ENSDART00000147966
si:dkeyp-68b7.10
chr20_+_46286082 0.25 ENSDART00000073519
trace amine associated receptor 14f
chr4_-_14531687 0.25 ENSDART00000182093
ENSDART00000159447
plexin b2a
chr7_+_71664624 0.24 ENSDART00000170273
elastin microfibril interfacer 2b
chr19_-_27564458 0.24 ENSDART00000123155
si:dkeyp-46h3.6
chr16_-_19568388 0.24 ENSDART00000141616
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr15_-_16884912 0.24 ENSDART00000062135
zgc:103681
chr8_+_32742650 0.24 ENSDART00000138117
hemicentin 2
chr23_-_1587955 0.23 ENSDART00000136037
fibronectin type III domain containing 7b
chr2_-_26476030 0.23 ENSDART00000145262
ENSDART00000132125
acyl-CoA dehydrogenase medium chain
chr17_+_20173882 0.23 ENSDART00000155379
si:ch211-248a14.8
chr21_-_37194365 0.22 ENSDART00000100286
fibroblast growth factor receptor 4
chr11_+_29965822 0.22 ENSDART00000127049
interleukin-1 family member A
chr8_+_30664077 0.22 ENSDART00000138750
adenosine A2a receptor a
chr25_-_35113891 0.22 ENSDART00000190724
zgc:165555
chr5_+_43870389 0.22 ENSDART00000141002
zgc:112966
chr21_+_29179887 0.22 ENSDART00000161941
si:ch211-57b15.1
chr21_+_29077509 0.22 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr2_-_31686353 0.22 ENSDART00000126177
ENSDART00000056679
E2F transcription factor 5
chr5_-_3839285 0.22 ENSDART00000122292
MLX interacting protein like
chr15_+_9121054 0.22 ENSDART00000193889
prostaglandin I2 receptor
chr18_-_48492951 0.22 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr24_-_25186895 0.21 ENSDART00000081029
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_-_65189 0.21 ENSDART00000168412
hydroxysteroid (17-beta) dehydrogenase 4
chr1_+_58094551 0.21 ENSDART00000146316
si:ch211-114l13.1
chr13_-_28688104 0.21 ENSDART00000133827
polycomb group ring finger 6
chr1_+_57176256 0.20 ENSDART00000152741
si:dkey-27j5.6
chr11_+_77526 0.20 ENSDART00000193521

chr9_+_13638329 0.20 ENSDART00000143432
amyotrophic lateral sclerosis 2a (juvenile)
chr21_-_5879897 0.20 ENSDART00000184034
ribosomal protein L35
chr19_+_7043634 0.20 ENSDART00000133954
major histocompatibility complex class I UKA
chr13_-_40726865 0.20 ENSDART00000099847
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr25_-_30429607 0.20 ENSDART00000162429
ENSDART00000176535
si:ch211-93f2.1
chr17_+_30546579 0.20 ENSDART00000154385
NHS-like 1a
chr16_-_1503023 0.20 ENSDART00000036348
single-minded family bHLH transcription factor 1a
chr15_-_28082310 0.20 ENSDART00000152620
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr19_-_27564980 0.20 ENSDART00000171967
si:dkeyp-46h3.8
chr24_-_21913426 0.20 ENSDART00000081178
C1q and TNF related 9
chr25_-_35591022 0.19 ENSDART00000188317
ENSDART00000187609
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr1_+_56955349 0.19 ENSDART00000152758
si:ch211-1f22.10
chr1_-_9641845 0.19 ENSDART00000121490
ENSDART00000159411
UDP glucuronosyltransferase 5 family, polypeptide B2
UDP glucuronosyltransferase 5 family, polypeptide B3
chr21_-_13055195 0.19 ENSDART00000133517
myogenesis regulating glycosidase (putative)
chr5_+_31605322 0.19 ENSDART00000135037
si:dkey-220k22.3
chr11_-_29996344 0.19 ENSDART00000003712
ENSDART00000126110
angiotensin I converting enzyme 2
chr5_+_42141917 0.19 ENSDART00000172201
ENSDART00000140743
transient receptor potential cation channel, subfamily V, member 1
chr23_+_27068225 0.19 ENSDART00000054238
major intrinsic protein of lens fiber a
chr20_-_42241150 0.19 ENSDART00000142791
NUS1 dehydrodolichyl diphosphate synthase subunit
chr4_+_57099307 0.19 ENSDART00000131654
si:ch211-238e22.2
chr12_-_4408828 0.19 ENSDART00000152447
si:ch211-173d10.1
chr11_-_6974022 0.19 ENSDART00000172851
si:ch211-43f4.1
chr12_-_34713888 0.18 ENSDART00000153272
BAH domain and coiled-coil containing 1b
chr22_-_4913031 0.18 ENSDART00000132062
si:ch73-256j6.3
chr22_-_4931063 0.18 ENSDART00000144103
si:ch73-256j6.2
chr15_-_23206562 0.18 ENSDART00000110360
coiled-coil domain containing 153
chr20_+_1088658 0.18 ENSDART00000162991

chr5_+_37035978 0.18 ENSDART00000167418
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr18_-_34549721 0.18 ENSDART00000137101
ENSDART00000021880
signal sequence receptor, gamma
chr16_+_54875530 0.18 ENSDART00000149795
nuclear receptor subfamily 0, group B, member 2a
chr17_+_6538733 0.18 ENSDART00000193712
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr13_+_13668991 0.18 ENSDART00000148266
Pim proto-oncogene, serine/threonine kinase, related 48
chr7_-_6279138 0.18 ENSDART00000173299
si:ch211-220f21.2
chr24_+_2961098 0.18 ENSDART00000163760
ENSDART00000170835
enoyl-CoA delta isomerase 2
chr5_-_30984010 0.18 ENSDART00000182367
spinster homolog 3 (Drosophila)
chr22_-_17595310 0.18 ENSDART00000099056
glutathione peroxidase 4a
chr10_+_43994471 0.17 ENSDART00000138242
ENSDART00000186359
claudin 5b
chr17_+_28670132 0.17 ENSDART00000076344
ENSDART00000164981
ENSDART00000182851
HECT domain containing 1
chr4_-_62561290 0.17 ENSDART00000155084
si:dkey-28k24.2
chr9_+_53637932 0.17 ENSDART00000188962

chr12_+_2648043 0.17 ENSDART00000082220
growth differentiation factor 2
chr23_+_17437554 0.17 ENSDART00000184282

chr9_+_8380728 0.17 ENSDART00000133501
si:ch1073-75o15.4
chr23_-_16734009 0.17 ENSDART00000125449
si:ch211-224l10.4
chr20_-_154989 0.17 ENSDART00000064542
ribosome production factor 2 homolog
chr4_-_76154252 0.17 ENSDART00000161269

Network of associatons between targets according to the STRING database.

First level regulatory network of rxraa+rxrab+rxrba+rxrgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.0 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 0.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.2 0.6 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.9 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 0.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 0.4 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.1 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 3.8 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.2 GO:0072020 proximal straight tubule development(GO:0072020)
0.1 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.2 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.3 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.2 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.2 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) vitamin transmembrane transport(GO:0035461) coenzyme transport(GO:0051182)
0.0 0.2 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.3 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.2 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 0.1 GO:0055057 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 1.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161) negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.3 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.5 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.5 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.9 GO:0048599 oocyte development(GO:0048599)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.2 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 2.1 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.1 GO:0044246 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.6 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.6 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.5 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.0 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.2 GO:0005948 acetolactate synthase complex(GO:0005948)
0.0 0.2 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.6 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 0.6 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.8 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.4 GO:1990825 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.1 0.7 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 1.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.3 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.2 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 4.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.2 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.1 0.2 GO:0003984 acetolactate synthase activity(GO:0003984)
0.1 0.9 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.0 1.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0070891 lipoteichoic acid binding(GO:0070891)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives