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PRJNA207719: Tissue specific transcriptome profiling

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Results for scrt1a+scrt1b+scrt2

Z-value: 0.82

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Transcription factors associated with scrt1a+scrt1b+scrt2

Gene Symbol Gene ID Gene Info
scrt1b
ENSDARG00000040214 scratch family zinc finger 1b
scrt2
ENSDARG00000056175 scratch family zinc finger 2
scrt1a
ENSDARG00000100821 scratch family zinc finger 1a
scrt1b
ENSDARG00000110984 scratch family zinc finger 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
scrt2dr11_v1_chr8_+_28527776_28527776-0.847.8e-02Click!
scrt1bdr11_v1_chr16_-_31188715_31188715-0.801.0e-01Click!
scrt1adr11_v1_chr19_+_1184878_1184878-0.751.4e-01Click!

Activity profile of scrt1a+scrt1b+scrt2 motif

Sorted Z-values of scrt1a+scrt1b+scrt2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_59851537 1.33 ENSDART00000180997
CU693479.1

chr13_+_8840772 0.87 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr10_+_9550419 0.64 ENSDART00000064977
si:ch211-243g18.2
si:ch211-243g18.2
chr20_+_40150612 0.59 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr19_+_7636941 0.58 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr19_-_3303995 0.57 ENSDART00000105150
si:ch211-133n4.9
si:ch211-133n4.9
chr23_+_36083529 0.51 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr10_-_41352502 0.50 ENSDART00000052971
ENSDART00000128156
rab11fip1b
RAB11 family interacting protein 1 (class I) b
chr19_+_31183495 0.49 ENSDART00000088618
meox2b
mesenchyme homeobox 2b
chr6_-_52675630 0.45 ENSDART00000083830
sdc4
syndecan 4
chr16_-_39570832 0.43 ENSDART00000039832
tgfbr2b
transforming growth factor beta receptor 2b
chr10_+_31809226 0.43 ENSDART00000087898
foxo1b
forkhead box O1 b
chr16_-_32975951 0.41 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr21_-_11646878 0.39 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
cast
calpastatin
chr15_+_3284684 0.38 ENSDART00000179778
foxo1a
forkhead box O1 a
chr7_+_61184551 0.38 ENSDART00000190788
zgc:194930
zgc:194930
chr17_-_2690083 0.38 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr23_-_32157865 0.37 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr5_-_9216758 0.36 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr7_-_29292206 0.35 ENSDART00000086753
dapk2a
death-associated protein kinase 2a
chr13_-_28688104 0.34 ENSDART00000133827
pcgf6
polycomb group ring finger 6
chr15_-_41245962 0.33 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr24_-_21903360 0.33 ENSDART00000091252
spata13
spermatogenesis associated 13
chr16_+_34111919 0.32 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr17_-_5583345 0.32 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr2_+_2470687 0.32 ENSDART00000184024
ENSDART00000061955
myl13
myosin, light chain 13
chr19_+_24575077 0.30 ENSDART00000167469
si:dkeyp-92c9.4
si:dkeyp-92c9.4
chr1_+_53377432 0.30 ENSDART00000177581
ucp1
uncoupling protein 1
chr20_+_34512130 0.28 ENSDART00000131637
prrx1b
paired related homeobox 1b
chr24_-_21903588 0.28 ENSDART00000180991
spata13
spermatogenesis associated 13
chr2_+_9560740 0.28 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr18_-_6766354 0.28 ENSDART00000132611
adm2b
adrenomedullin 2b
chr24_+_13735616 0.28 ENSDART00000184267
msc
musculin (activated B-cell factor-1)
chr10_-_13396720 0.27 ENSDART00000030976
il11ra
interleukin 11 receptor, alpha
chr11_+_6650966 0.27 ENSDART00000131236
si:dkey-246j7.1
si:dkey-246j7.1
chr13_-_42560662 0.26 ENSDART00000124898
CR792417.1

chr11_+_21076872 0.26 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr3_+_42923275 0.26 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr7_+_22585447 0.26 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr13_+_13578552 0.25 ENSDART00000101673
foxi2
forkhead box I2
chr17_+_26543690 0.25 ENSDART00000156417
sparcl2
SPARC-like 2
chr16_+_14684916 0.24 ENSDART00000138611
col14a1a
collagen, type XIV, alpha 1a
chr17_-_30521043 0.24 ENSDART00000087111
itsn2b
intersectin 2b
chr17_-_49443399 0.24 ENSDART00000155293
cga
glycoprotein hormones, alpha polypeptide
chr17_-_49443247 0.24 ENSDART00000059245
cga
glycoprotein hormones, alpha polypeptide
chr22_-_6144428 0.23 ENSDART00000106118
si:dkey-19a16.4
si:dkey-19a16.4
chr5_+_44806374 0.23 ENSDART00000184237
ctsla
cathepsin La
chr18_+_38191346 0.23 ENSDART00000052703
nucb2b
nucleobindin 2b
chr11_+_7261981 0.22 ENSDART00000130400
ENSDART00000155427
reep6
receptor accessory protein 6
chr2_+_3201345 0.22 ENSDART00000130349
wnt9a
wingless-type MMTV integration site family, member 9A
chr8_-_1051438 0.22 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr14_+_35424539 0.22 ENSDART00000171809
ENSDART00000162185
sytl4
synaptotagmin-like 4
chr20_-_52271262 0.21 ENSDART00000135463
rhpn1
rhophilin, Rho GTPase binding protein 1
chr4_+_16710001 0.21 ENSDART00000035899
pkp2
plakophilin 2
chr7_+_49664174 0.21 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr7_-_7823662 0.21 ENSDART00000167652
cxcl8b.3
chemokine (C-X-C motif) ligand 8b, duplicate 3
chr25_-_3139805 0.20 ENSDART00000166625
epx
eosinophil peroxidase
chr3_+_37574885 0.20 ENSDART00000055225
wnt9b
wingless-type MMTV integration site family, member 9B
chr15_+_17848590 0.20 ENSDART00000168940
zgc:113279
zgc:113279
chr2_+_10766744 0.20 ENSDART00000015379
gfi1aa
growth factor independent 1A transcription repressor a
chr12_-_28818720 0.19 ENSDART00000134453
ENSDART00000141727
prr15lb
proline rich 15-like b
chr8_-_9684872 0.19 ENSDART00000132158
ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr20_+_34511678 0.19 ENSDART00000061588
prrx1b
paired related homeobox 1b
chr16_-_17072440 0.19 ENSDART00000002493
ENSDART00000178443
tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr20_-_52271015 0.19 ENSDART00000074307
rhpn1
rhophilin, Rho GTPase binding protein 1
chr4_-_8040436 0.19 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr15_+_5923851 0.19 ENSDART00000152520
ENSDART00000145827
ENSDART00000121529
sh3bgr
SH3 domain binding glutamate-rich protein
chr25_-_29074064 0.19 ENSDART00000165603
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr4_-_8035520 0.18 ENSDART00000146146
si:ch211-240l19.7
si:ch211-240l19.7
chr4_+_2228754 0.18 ENSDART00000166058
cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr20_+_21583639 0.18 ENSDART00000131069
esr2a
estrogen receptor 2a
chr7_-_71456117 0.18 ENSDART00000042492
sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr13_-_36844945 0.18 ENSDART00000129562
ENSDART00000150899
nin
ninein (GSK3B interacting protein)
chr13_-_39159810 0.17 ENSDART00000131508
col9a1b
collagen, type IX, alpha 1b
chr8_-_24970790 0.17 ENSDART00000141267
si:ch211-199o1.2
si:ch211-199o1.2
chr4_-_78026285 0.17 ENSDART00000168273
CCT2
chaperonin containing TCP1 subunit 2
chr3_+_53240562 0.17 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr12_+_33484458 0.16 ENSDART00000000069
slc9a3r1a
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr14_+_29941266 0.16 ENSDART00000112757
fam149a
family with sequence similarity 149 member A
chr12_+_13742953 0.16 ENSDART00000152257
ppp1r16a
protein phosphatase 1, regulatory subunit 16A
chr24_+_24086491 0.16 ENSDART00000145092
lipib
lipase, member Ib
chr25_+_30074947 0.16 ENSDART00000154849
si:ch211-147k10.5
si:ch211-147k10.5
chr23_+_37579107 0.16 ENSDART00000169376
plekhg5b
pleckstrin homology domain containing, family G (with RhoGef domain) member 5b
chr2_-_10563576 0.16 ENSDART00000185818
ENSDART00000190887
ccdc18
coiled-coil domain containing 18
chr12_-_4916969 0.15 ENSDART00000161680
ifnphi4
interferon phi 4
chr7_-_18700364 0.15 ENSDART00000112359
si:ch211-119e14.9
si:ch211-119e14.9
chr2_-_32247341 0.15 ENSDART00000146452
fam49ba
family with sequence similarity 49, member Ba
chr23_+_38245610 0.15 ENSDART00000191386
znf217
zinc finger protein 217
chr8_+_26034623 0.15 ENSDART00000004521
ENSDART00000142555
arih2
ariadne homolog 2 (Drosophila)
chr7_+_4625915 0.15 ENSDART00000108557
si:ch211-225k7.3
si:ch211-225k7.3
chr3_-_50046004 0.15 ENSDART00000109544
si:ch1073-100f3.2
si:ch1073-100f3.2
chr17_+_34186632 0.14 ENSDART00000014306
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr13_+_24584401 0.14 ENSDART00000057599
fuom
fucose mutarotase
chr14_+_22152060 0.14 ENSDART00000082697
ENSDART00000054982
gabra6a
gamma-aminobutyric acid (GABA) A receptor, alpha 6a
chr24_+_26742226 0.14 ENSDART00000079721
ghsrb
growth hormone secretagogue receptor b
chr17_-_47090440 0.14 ENSDART00000163542
CABZ01056321.1

chr18_-_10995410 0.14 ENSDART00000136751
tspan33b
tetraspanin 33b
chr23_-_15090782 0.13 ENSDART00000133624
si:ch211-218g4.2
si:ch211-218g4.2
chr8_+_9684479 0.13 ENSDART00000132031
mon1ba
MON1 secretory trafficking family member Ba
chr7_+_4524059 0.13 ENSDART00000187693
si:dkey-83f18.4
si:dkey-83f18.4
chr23_+_4741543 0.13 ENSDART00000144761
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
chr2_-_10564019 0.12 ENSDART00000132167
ccdc18
coiled-coil domain containing 18
chr4_+_8532580 0.12 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr21_+_3778498 0.11 ENSDART00000139813
tor1
torsin family 1
chr3_-_34103123 0.11 ENSDART00000180590
ighv6-1
immunoglobulin heavy variable 6-1
chr15_+_15390882 0.11 ENSDART00000062024
ca4b
carbonic anhydrase IV b
chr14_-_46897067 0.11 ENSDART00000058789
qdpra
quinoid dihydropteridine reductase a
chr8_-_13985032 0.10 ENSDART00000140576
igf3
insulin-like growth factor 3
chr24_+_25913162 0.10 ENSDART00000143099
ENSDART00000184814
map3k15
mitogen-activated protein kinase kinase kinase 15
chr5_-_16218777 0.10 ENSDART00000141698
kremen1
kringle containing transmembrane protein 1
chr3_-_30158395 0.10 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr9_+_44034990 0.10 ENSDART00000162406
itga4
integrin alpha 4
chr3_+_34846201 0.10 ENSDART00000055263
itga3a
integrin, alpha 3a
chr14_+_6423973 0.10 ENSDART00000051556
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr21_-_9562272 0.10 ENSDART00000162225
ENSDART00000163874
ENSDART00000168173
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr7_-_20836625 0.10 ENSDART00000192566
cldn15a
claudin 15a
chr7_-_54677143 0.09 ENSDART00000163748
ccnd1
cyclin D1
chr5_-_1047222 0.09 ENSDART00000181112
mbd2
methyl-CpG binding domain protein 2
chr6_+_27361978 0.09 ENSDART00000065238
crocc2
ciliary rootlet coiled-coil, rootletin family member 2
chr1_-_21204114 0.09 ENSDART00000141077
si:dkey-253i9.4
si:dkey-253i9.4
chr24_-_10897511 0.09 ENSDART00000145593
ENSDART00000102484
ENSDART00000066784
fam49bb
family with sequence similarity 49, member Bb
chr15_+_20529197 0.09 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr11_+_39928828 0.09 ENSDART00000137516
ENSDART00000134082
vamp3
vesicle-associated membrane protein 3 (cellubrevin)
chr8_+_46939566 0.08 ENSDART00000139422
espn
espin
chr23_+_27740592 0.08 ENSDART00000137875
dhh
desert hedgehog
chr2_-_26476030 0.08 ENSDART00000145262
ENSDART00000132125
acadm
acyl-CoA dehydrogenase medium chain
chr5_-_29587351 0.08 ENSDART00000136446
ENSDART00000051434
entpd2a.1
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 1
chr22_+_26600834 0.07 ENSDART00000157411
adcy9
adenylate cyclase 9
chr9_+_48415043 0.07 ENSDART00000159930
lrp2a
low density lipoprotein receptor-related protein 2a
chr22_-_10891213 0.07 ENSDART00000145229
arhgef18b
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr16_-_33930759 0.07 ENSDART00000177453
dnali1
dynein, axonemal, light intermediate chain 1
chr23_+_27740788 0.07 ENSDART00000053871
dhh
desert hedgehog
chr13_+_25486608 0.07 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr17_-_6508406 0.06 ENSDART00000002778
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr23_-_31400792 0.06 ENSDART00000132736
lca5
Leber congenital amaurosis 5
chr21_+_22237964 0.06 ENSDART00000003181
myo7ab
myosin VIIAb
chr11_+_14321113 0.06 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
ptbp1b
polypyrimidine tract binding protein 1b
chr5_+_27525477 0.06 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr19_+_41520892 0.05 ENSDART00000182218
ENSDART00000115123
crtc2
CREB regulated transcription coactivator 2
chr21_-_4849029 0.05 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr8_+_11425048 0.05 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr3_-_61494840 0.05 ENSDART00000101957
baiap2l1b
BAI1-associated protein 2-like 1b
chr4_+_18489207 0.05 ENSDART00000135276
si:dkey-202b22.5
si:dkey-202b22.5
chr9_+_44034790 0.05 ENSDART00000166110
ENSDART00000176954
itga4
integrin alpha 4
chr12_+_28854963 0.05 ENSDART00000153227
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr3_-_31079186 0.05 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr25_-_893464 0.05 ENSDART00000159321
znf609a
zinc finger protein 609a
chr21_+_20229926 0.04 ENSDART00000025860
si:dkey-247m21.3
si:dkey-247m21.3
chr2_+_25378457 0.03 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr12_+_20678187 0.03 ENSDART00000146762
st6galnac1.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 1
chr19_+_1831911 0.03 ENSDART00000166653
ptk2aa
protein tyrosine kinase 2aa
chr22_-_6362442 0.03 ENSDART00000149907
ENSDART00000106104
zgc:113298
zgc:113298
chr12_+_5209822 0.03 ENSDART00000152610
SLC35G1
si:ch211-197g18.2
chr11_+_21587950 0.02 ENSDART00000162251
FAM72B
zgc:101564
chr16_+_33930864 0.02 ENSDART00000125945
snip1
Smad nuclear interacting protein
chr4_+_31085014 0.02 ENSDART00000172541
si:dkey-47k16.4
si:dkey-47k16.4
chr8_-_44868020 0.02 ENSDART00000142712
cacna1fa
calcium channel, voltage-dependent, L type, alpha 1F subunit a
chr6_+_37308716 0.02 ENSDART00000085498
ptger3
prostaglandin E receptor 3 (subtype EP3)
chr24_+_22022109 0.02 ENSDART00000133686
ropn1l
rhophilin associated tail protein 1-like
chr6_+_46309795 0.01 ENSDART00000154817
si:dkeyp-67f1.1
si:dkeyp-67f1.1
chr21_+_8276989 0.01 ENSDART00000028265
nr5a1b
nuclear receptor subfamily 5, group A, member 1b
chr10_-_19523752 0.01 ENSDART00000160057
si:ch211-127i16.2
si:ch211-127i16.2
chr23_-_43713757 0.00 ENSDART00000192175
abce1
ATP-binding cassette, sub-family E (OABP), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of scrt1a+scrt1b+scrt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
0.1 0.5 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.1 0.2 GO:0002631 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0051793 medium-chain fatty acid metabolic process(GO:0051791) medium-chain fatty acid catabolic process(GO:0051793)
0.0 0.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.7 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.2 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.0 GO:0032098 regulation of appetite(GO:0032098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)