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PRJNA207719: Tissue specific transcriptome profiling

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Results for six6a+six6b

Z-value: 0.60

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Transcription factors associated with six6a+six6b

Gene Symbol Gene ID Gene Info
six6a
ENSDARG00000025187 SIX homeobox 6a
six6b
ENSDARG00000031316 SIX homeobox 6b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
six6adr11_v1_chr13_+_31583034_315830340.602.8e-01Click!
six6bdr11_v1_chr20_-_20533865_205338650.504.0e-01Click!

Activity profile of six6a+six6b motif

Sorted Z-values of six6a+six6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_35745572 1.13 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr14_+_51098036 0.72 ENSDART00000184118
CABZ01078594.1

chr2_-_44946094 0.60 ENSDART00000036997
camk2n1a
calcium/calmodulin-dependent protein kinase II inhibitor 1a
chr14_+_50770537 0.48 ENSDART00000158723
sncb
synuclein, beta
chr9_+_38883388 0.41 ENSDART00000135902
map2
microtubule-associated protein 2
chr15_-_20939579 0.40 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr15_-_25527580 0.38 ENSDART00000167005
ENSDART00000157498
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr2_+_47581997 0.36 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr2_+_1881334 0.32 ENSDART00000161420
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr13_+_28819768 0.31 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr19_+_206835 0.31 ENSDART00000161137
scn1bb
sodium channel, voltage-gated, type I, beta b
chr19_-_32710922 0.31 ENSDART00000004034
hpca
hippocalcin
chr20_-_49729446 0.30 ENSDART00000111089
filip1b
filamin A interacting protein 1b
chr21_-_26250744 0.30 ENSDART00000044735
gria1b
glutamate receptor, ionotropic, AMPA 1b
chr21_-_42007213 0.28 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gabrg2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr10_+_39199547 0.27 ENSDART00000075943
ei24
etoposide induced 2.4
chr21_-_26250443 0.26 ENSDART00000123713
gria1b
glutamate receptor, ionotropic, AMPA 1b
chr7_+_20535869 0.25 ENSDART00000078181
zgc:158423
zgc:158423
chr5_-_39736383 0.23 ENSDART00000127123
rasgef1ba
RasGEF domain family, member 1Ba
chr3_-_39305291 0.22 ENSDART00000102674
plcd3a
phospholipase C, delta 3a
chr5_+_64368770 0.22 ENSDART00000162246
plpp7
phospholipid phosphatase 7 (inactive)
chr6_+_11026866 0.21 ENSDART00000189619
abcc6a
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a
chr21_-_42055872 0.21 ENSDART00000144767
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_-_27775236 0.20 ENSDART00000187983
XKR4
zgc:123035
chr8_-_33114202 0.19 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr3_-_18711288 0.19 ENSDART00000183885
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr3_-_22214029 0.19 ENSDART00000154818
maptb
microtubule-associated protein tau b
chr24_-_19719240 0.19 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr20_+_1960092 0.18 ENSDART00000191892
CABZ01103860.1

chr10_-_38243851 0.18 ENSDART00000166108
usp25
ubiquitin specific peptidase 25
chr22_-_12862415 0.18 ENSDART00000145156
ENSDART00000137280
glsa
glutaminase a
chr12_+_47448558 0.17 ENSDART00000185689
ENSDART00000105328
fmn2b
formin 2b
chr6_-_49159207 0.16 ENSDART00000041942
tspan2a
tetraspanin 2a
chr16_+_1802307 0.16 ENSDART00000180026
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr2_+_53357953 0.16 ENSDART00000187577
celf5b
cugbp, Elav-like family member 5b
chr20_+_12702923 0.15 ENSDART00000163499
zgc:153383
zgc:153383
chr2_-_30249746 0.15 ENSDART00000124153
ENSDART00000142575
elocb
elongin C paralog b
chr1_+_54198893 0.15 ENSDART00000158948
tsc2
TSC complex subunit 2
chr15_-_2596125 0.15 ENSDART00000114923
dnajc30b
DnaJ (Hsp40) homolog, subfamily C, member 30b
chr19_-_3906369 0.15 ENSDART00000160299
ENSDART00000169205
si:ch73-281i18.4
si:ch73-281i18.4
chr7_-_31932723 0.15 ENSDART00000014843
bdnf
brain-derived neurotrophic factor
chr3_-_21106093 0.15 ENSDART00000156566
maza
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr10_-_5821584 0.15 ENSDART00000166388
il6st
interleukin 6 signal transducer
chr5_-_57526807 0.14 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr7_-_36358735 0.14 ENSDART00000188392
fto
fat mass and obesity associated
chr2_-_144393 0.14 ENSDART00000156008
adcy1b
adenylate cyclase 1b
chr19_-_3925801 0.13 ENSDART00000129570
ENSDART00000163138
si:ch73-281i18.6
si:ch73-281i18.6
chr1_+_27713380 0.13 ENSDART00000169584
si:dkey-29d5.1
si:dkey-29d5.1
chr25_+_31277415 0.13 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr1_+_14466860 0.13 ENSDART00000114097
stim2a
tromal interaction molecule 2a
chr25_+_33072676 0.13 ENSDART00000182885
ENSDART00000181516
tln2b
talin 2b
chr2_-_30250311 0.12 ENSDART00000184144
elocb
elongin C paralog b
chr23_-_36934944 0.12 ENSDART00000109976
ENSDART00000162179
acap3a
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3a
chr18_-_14677936 0.12 ENSDART00000111995
si:dkey-238o13.4
si:dkey-238o13.4
chr6_-_18199062 0.12 ENSDART00000167513
ppp1r27b
protein phosphatase 1, regulatory subunit 27b
chr18_-_19350792 0.12 ENSDART00000147902
megf11
multiple EGF-like-domains 11
chr2_-_9607879 0.12 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr6_+_28124393 0.11 ENSDART00000089195
gpr17
G protein-coupled receptor 17
chr18_+_12058403 0.11 ENSDART00000140854
ENSDART00000193632
ENSDART00000190519
ENSDART00000190685
ENSDART00000112671
bicd1a
bicaudal D homolog 1a
chr17_+_28882977 0.11 ENSDART00000153937
prkd1
protein kinase D1
chr10_+_45302425 0.11 ENSDART00000159954
zmiz2
zinc finger, MIZ-type containing 2
chr10_-_43540196 0.11 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr16_+_30002605 0.11 ENSDART00000160555
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr10_+_7563755 0.11 ENSDART00000165877
purg
purine-rich element binding protein G
chr16_-_23471387 0.11 ENSDART00000180899
CR533578.1

chr10_+_44903676 0.10 ENSDART00000158553
zgc:114173
zgc:114173
chr24_+_13017586 0.10 ENSDART00000142457
stau2
staufen double-stranded RNA binding protein 2
chr7_+_71955486 0.10 ENSDART00000189349
CABZ01071171.1
Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA.
chr10_+_23060391 0.10 ENSDART00000079711
slc25a1a
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr12_+_17439580 0.10 ENSDART00000189257
atad1b
ATPase family, AAA domain containing 1b
chr15_-_42736433 0.10 ENSDART00000154379
si:ch211-181d7.1
si:ch211-181d7.1
chr12_+_2446837 0.10 ENSDART00000112032
ARHGAP22
si:dkey-191m6.4
chr20_+_37383034 0.09 ENSDART00000134997
ENSDART00000145927
adgrg6
adhesion G protein-coupled receptor G6
chr10_+_7564106 0.09 ENSDART00000159042
purg
purine-rich element binding protein G
chr22_-_10459880 0.09 ENSDART00000064801
ogn
osteoglycin
chr25_+_3306620 0.09 ENSDART00000182085
ENSDART00000034704
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr20_+_34596205 0.09 ENSDART00000138338
si:ch211-242b18.1
si:ch211-242b18.1
chr11_-_17755444 0.09 ENSDART00000154627
eogt
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr18_+_16133595 0.09 ENSDART00000080423
ctsd
cathepsin D
chr20_-_16849306 0.09 ENSDART00000131395
ENSDART00000027582
brms1lb
breast cancer metastasis-suppressor 1-like b
chr17_+_24722646 0.08 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr23_-_44226556 0.08 ENSDART00000149115
zgc:158659
zgc:158659
chr8_+_17143501 0.08 ENSDART00000061758
mier3b
mesoderm induction early response 1, family member 3 b
chr10_-_39198942 0.08 ENSDART00000077619
b3gat1b
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
chr25_-_24248000 0.08 ENSDART00000073527
spty2d1
SPT2 chromatin protein domain containing 1
chr18_+_19842569 0.07 ENSDART00000147470
iqch
IQ motif containing H
chr16_+_6632969 0.07 ENSDART00000109276
sall3a
spalt-like transcription factor 3a
chr13_+_49175624 0.07 ENSDART00000193550
egln1a
egl-9 family hypoxia-inducible factor 1a
chr8_-_28357177 0.07 ENSDART00000182319
KLHL12 (1 of many)
kelch like family member 12
chr8_-_21142550 0.07 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr20_-_40487208 0.07 ENSDART00000075070
ENSDART00000142029
hsf2
heat shock transcription factor 2
chr7_+_69428831 0.07 ENSDART00000186975
elp5
elongator acetyltransferase complex subunit 5
chr20_+_42918755 0.07 ENSDART00000134855
efr3bb
EFR3 homolog Bb (S. cerevisiae)
chr20_-_37287107 0.07 ENSDART00000076309
nmbr
neuromedin B receptor
chr19_+_27342479 0.06 ENSDART00000184687
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr24_-_20016817 0.06 ENSDART00000082201
ENSDART00000189448
slc22a13b
solute carrier family 22 member 13b
chr21_+_11105007 0.06 ENSDART00000128859
ENSDART00000193105
prlra
prolactin receptor a
chr21_-_35428039 0.06 ENSDART00000193298
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr16_+_44906324 0.06 ENSDART00000074960
cd22
cd22 molecule
chr8_-_13184989 0.06 ENSDART00000135738
zgc:194990
zgc:194990
chr15_-_31514818 0.06 ENSDART00000153978
hmgb1b
high mobility group box 1b
chr2_-_3611960 0.06 ENSDART00000184579
pter
phosphotriesterase related
chr12_-_16380961 0.06 ENSDART00000086984
hectd2
HECT domain containing 2
chr17_+_23255365 0.06 ENSDART00000180277
AL935174.5

chr18_+_36786842 0.06 ENSDART00000123264
si:ch211-160d20.3
si:ch211-160d20.3
chr4_+_76426308 0.06 ENSDART00000180424
ENSDART00000159789
FP074874.1
zgc:172128

zgc:172128
chr11_-_27702778 0.06 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr14_+_45883687 0.06 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr2_+_30249977 0.06 ENSDART00000109160
ENSDART00000135171
tmem70
transmembrane protein 70
chr23_+_1702624 0.06 ENSDART00000149357
rabggta
Rab geranylgeranyltransferase, alpha subunit
chr8_-_37461835 0.06 ENSDART00000013446
eif2d
eukaryotic translation initiation factor 2D
chr23_+_7710447 0.05 ENSDART00000168199
kif3b
kinesin family member 3B
chr5_-_30079434 0.05 ENSDART00000133981
bco2a
beta-carotene oxygenase 2a
chr14_-_2318590 0.05 ENSDART00000192735
pcdh2ab8
protocadherin 2 alpha b 8
chr14_-_17306261 0.05 ENSDART00000191747
jakmip1
janus kinase and microtubule interacting protein 1
chr24_-_39772045 0.05 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr23_-_38497705 0.05 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr4_-_13902188 0.05 ENSDART00000032805
gxylt1b
glucoside xylosyltransferase 1b
chr24_-_7587401 0.04 ENSDART00000093163
galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr13_+_46944607 0.04 ENSDART00000187352
fbxo5
F-box protein 5
chr18_+_43183749 0.04 ENSDART00000151166
nectin1b
nectin cell adhesion molecule 1b
chr1_-_19233890 0.04 ENSDART00000127145
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr8_-_12847483 0.04 ENSDART00000146186
si:dkey-104n9.1
si:dkey-104n9.1
chr13_-_18195942 0.04 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr18_+_31410652 0.04 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr23_-_24047054 0.04 ENSDART00000184308
ENSDART00000185902
CR925720.1

chr11_+_44804685 0.04 ENSDART00000163660
strn
striatin, calmodulin binding protein
chr5_+_68267908 0.04 ENSDART00000130835
tnfsf13
TNF superfamily member 13
chr3_+_18840810 0.04 ENSDART00000181137
ENSDART00000128626
ENSDART00000133332
tmem104
transmembrane protein 104
chr8_+_2575993 0.04 ENSDART00000112914
si:ch211-51h9.7
si:ch211-51h9.7
chr22_+_19640309 0.04 ENSDART00000061725
ENSDART00000140819
rgmd
RGM domain family, member D
chr10_-_25816558 0.03 ENSDART00000017240
postna
periostin, osteoblast specific factor a
chr4_+_11458078 0.03 ENSDART00000037600
ankrd16
ankyrin repeat domain 16
chr19_-_17774875 0.03 ENSDART00000151133
ENSDART00000130695
top2b
DNA topoisomerase II beta
chr4_-_73266929 0.03 ENSDART00000158194
wu:fc30c06
wu:fc30c06
chr7_-_7766920 0.03 ENSDART00000173376
intu
inturned planar cell polarity protein
chr12_-_21834611 0.03 ENSDART00000179553
thrab
thyroid hormone receptor alpha b
chr15_-_762319 0.03 ENSDART00000154306
ENSDART00000157492
si:dkey-7i4.16
znf1011
si:dkey-7i4.16
zinc finger protein 1011
chr21_-_25756119 0.03 ENSDART00000002341
cldnc
claudin c
chr25_+_1335530 0.03 ENSDART00000090803
fem1b
fem-1 homolog b (C. elegans)
chr20_-_51946052 0.02 ENSDART00000074325
dusp10
dual specificity phosphatase 10
chr14_+_26759332 0.02 ENSDART00000088484
ahnak
AHNAK nucleoprotein
chr3_-_61387273 0.02 ENSDART00000156479
znf1143
zinc finger protein 1143
chr10_+_41549819 0.02 ENSDART00000114210
CABZ01049847.1

chr5_+_25304499 0.02 ENSDART00000163425
carnmt1
carnosine N-methyltransferase 1
chr14_-_17576391 0.02 ENSDART00000161355
ENSDART00000168959
rnf4
ring finger protein 4
chr22_-_21845685 0.02 ENSDART00000105564
aes
amino-terminal enhancer of split
chr16_-_36979592 0.02 ENSDART00000168443
snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr5_+_31995683 0.02 ENSDART00000139744
scai
suppressor of cancer cell invasion
chr20_+_26987416 0.02 ENSDART00000012816
sel1l
sel-1 suppressor of lin-12-like (C. elegans)
chr7_+_22313533 0.02 ENSDART00000123457
TMEM102
si:dkey-11f12.2
chr25_+_15287036 0.02 ENSDART00000147572
hipk3a
homeodomain interacting protein kinase 3a
chr20_-_29471577 0.02 ENSDART00000043382
grem1a
gremlin 1a, DAN family BMP antagonist
chr19_+_35002479 0.02 ENSDART00000103266
wdyhv1
WDYHV motif containing 1
chr19_+_390298 0.01 ENSDART00000136361
sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr23_+_32335871 0.01 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr1_+_31657842 0.01 ENSDART00000057880
poll
polymerase (DNA directed), lambda
chr7_-_38807819 0.01 ENSDART00000132772
ENSDART00000052324
atg13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr6_-_32315494 0.01 ENSDART00000127879
atg4c
autophagy related 4C, cysteine peptidase
chr16_+_3185541 0.01 ENSDART00000024088
wdr21
WD repeat domain 21
chr7_+_38808027 0.01 ENSDART00000052323
harbi1
harbinger transposase derived 1
chr22_+_1431743 0.01 ENSDART00000182871
BX322657.2
Danio rerio si:dkeyp-53d3.6 (si:dkeyp-53d3.6), mRNA.
chr1_+_34701144 0.00 ENSDART00000150038
gtf2f2a
general transcription factor IIF, polypeptide 2a
chr15_-_30450898 0.00 ENSDART00000156584
msi2b
musashi RNA-binding protein 2b
chr13_+_21826096 0.00 ENSDART00000056432
zswim8
zinc finger, SWIM-type containing 8
chr20_-_9580446 0.00 ENSDART00000014168
zfp36l1b
zinc finger protein 36, C3H type-like 1b
chr2_-_23391266 0.00 ENSDART00000159048
ivns1abpb
influenza virus NS1A binding protein b
chr20_-_36393555 0.00 ENSDART00000153421
si:dkey-1j5.4
si:dkey-1j5.4
chr21_-_2707768 0.00 ENSDART00000165384
CABZ01101739.1

Network of associatons between targets according to the STRING database.

First level regulatory network of six6a+six6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.3 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.0 0.1 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.1 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.0 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.0 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0035516 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors