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PRJNA207719: Tissue specific transcriptome profiling

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Results for sox14+sox14-1+sox21a

Z-value: 1.26

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Transcription factors associated with sox14+sox14-1+sox21a

Gene Symbol Gene ID Gene Info
sox21a
ENSDARG00000031664 SRY-box transcription factor 21a
sox14
ENSDARG00000070929 SRY-box transcription factor 14
sox21a
ENSDARG00000111842 SRY-box transcription factor 21a
sox14-1
ENSDARG00000111969 SRY-box transcription factor 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FQ377628.2dr11_v1_chr2_-_22575851_22575851-0.801.1e-01Click!
sox14dr11_v1_chr6_-_26559921_26559921-0.701.9e-01Click!
sox21adr11_v1_chr6_+_7414215_74142150.256.8e-01Click!

Activity profile of sox14+sox14-1+sox21a motif

Sorted Z-values of sox14+sox14-1+sox21a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_11457500 1.51 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr25_+_25202213 1.40 ENSDART00000150744
ccl39a.10
chemokine (C-C motif) ligand 39, duplicate 10
chr17_+_53292215 1.19 ENSDART00000170686
si:ch1073-416d2.3
si:ch1073-416d2.3
chr24_-_11076400 1.12 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr15_-_21132480 1.07 ENSDART00000078734
ENSDART00000157481
a2ml
alpha-2-macroglobulin-like
chr12_-_4346085 1.04 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr25_-_12982193 0.99 ENSDART00000159617
ccl39.5
chemokine (C-C motif) ligand 39, duplicate 5
chr19_-_7420867 0.90 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr23_-_3758637 0.89 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr12_-_17655683 0.87 ENSDART00000066411
dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr20_+_54312970 0.85 ENSDART00000024598
ENSDART00000193172
zp2.5
zona pellucida glycoprotein 2, tandem duplicate 5
chr2_-_39017838 0.81 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr22_-_15693085 0.74 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr5_+_43782267 0.73 ENSDART00000130355
nos2a
nitric oxide synthase 2a, inducible
chr3_-_34069637 0.73 ENSDART00000151588
ighv9-1
immunoglobulin heavy variable 9-1
chr18_+_46151505 0.71 ENSDART00000015034
ENSDART00000141287
blvrb
biliverdin reductase B
chr8_-_32385989 0.70 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr5_-_41531629 0.69 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr2_-_36933472 0.69 ENSDART00000170405
BX470229.2

chr16_-_51888952 0.69 ENSDART00000186407
ENSDART00000175435
rpl28
ribosomal protein L28
chr8_-_45760087 0.68 ENSDART00000025620
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr20_+_54309148 0.66 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr23_-_6641223 0.66 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr20_+_54295213 0.65 ENSDART00000074085
zp2.3
zona pellucida glycoprotein 2, tandem duplicate 3
chr20_+_54299419 0.65 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr22_-_24967348 0.64 ENSDART00000153490
ENSDART00000084871
fam20cl
family with sequence similarity 20, member C like
chr15_+_22390076 0.64 ENSDART00000183764
oafa
OAF homolog a (Drosophila)
chr1_-_49225890 0.63 ENSDART00000111598
cxcl18b
chemokine (C-X-C motif) ligand 18b
chr14_+_46313135 0.63 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr5_+_37068223 0.59 ENSDART00000164279
si:dkeyp-110c7.4
si:dkeyp-110c7.4
chr2_-_56348727 0.59 ENSDART00000060745
uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr12_-_2800809 0.59 ENSDART00000152682
ENSDART00000083784
ubtd1b
ubiquitin domain containing 1b
chr9_-_24244383 0.58 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr9_+_563547 0.57 ENSDART00000162761
CU984600.2

chr1_-_18848955 0.57 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr14_-_246342 0.56 ENSDART00000054823
aurkb
aurora kinase B
chr3_-_59297532 0.55 ENSDART00000187991
CABZ01053748.1

chr6_+_7466223 0.55 ENSDART00000148908
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr6_+_584632 0.55 ENSDART00000151150
zgc:92360
zgc:92360
chr16_-_17056630 0.53 ENSDART00000138715
plekhg6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr12_+_22576404 0.53 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr3_-_50139860 0.51 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr23_-_19715799 0.51 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
rpl10
ribosomal protein L10
chr10_-_342564 0.50 ENSDART00000157633
vaspa
vasodilator stimulated phosphoprotein a
chr8_-_46486009 0.49 ENSDART00000140431
sult1st9
sulfotransferase family 1, cytosolic sulfotransferase 9
chr2_+_36004381 0.48 ENSDART00000098706
lamc2
laminin, gamma 2
chr6_+_30668098 0.47 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr3_+_3545825 0.47 ENSDART00000109060
CR589947.1

chr8_-_20243389 0.46 ENSDART00000184904
acer1
alkaline ceramidase 1
chr25_-_13023569 0.45 ENSDART00000167232
ccl39.1
chemokine (C-C motif) ligand 39, duplicate 1
chr2_-_28420415 0.44 ENSDART00000183857
CABZ01056051.1

chr22_+_30631072 0.43 ENSDART00000059970
zmp:0000000606
zmp:0000000606
chr1_+_59088205 0.43 ENSDART00000150649
ENSDART00000100197
zgc:173915
zgc:173915
chr11_+_14280598 0.42 ENSDART00000163033
si:ch211-262i1.3
si:ch211-262i1.3
chr7_-_19915414 0.42 ENSDART00000144180
zgc:110591
zgc:110591
chr7_-_51953807 0.41 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr3_+_41714966 0.40 ENSDART00000155440
eif3ba
eukaryotic translation initiation factor 3, subunit Ba
chr11_-_11791718 0.40 ENSDART00000180476
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr16_-_40373836 0.39 ENSDART00000134498
si:dkey-242e21.3
si:dkey-242e21.3
chr5_-_30615901 0.39 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr15_+_29025090 0.39 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr15_+_37331585 0.39 ENSDART00000170715
zgc:171592
zgc:171592
chr7_-_34294613 0.39 ENSDART00000191632
CR388195.1

chr11_-_44498975 0.38 ENSDART00000173066
ENSDART00000189976
si:ch1073-365p7.2
si:ch1073-365p7.2
chr5_+_38680247 0.37 ENSDART00000132763
si:dkey-58f10.11
si:dkey-58f10.11
chr5_+_38631687 0.37 ENSDART00000147280
si:ch211-271e10.6
si:ch211-271e10.6
chr15_+_38006366 0.37 ENSDART00000156162
si:dkey-238d18.13
si:dkey-238d18.13
chr15_-_36533322 0.36 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr7_+_35268880 0.36 ENSDART00000182231
dpep2
dipeptidase 2
chr11_+_29965822 0.35 ENSDART00000127049
il1fma
interleukin-1 family member A
chr25_-_12998202 0.35 ENSDART00000171661
ccl39.3
chemokine (C-C motif) ligand 39, duplicate 3
chr19_-_32849036 0.35 ENSDART00000131518
si:dkey-284p5.3
si:dkey-284p5.3
chr16_+_35535375 0.35 ENSDART00000171675
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr23_+_10352921 0.35 ENSDART00000081193
KRT18 (1 of many)
si:ch211-133j6.3
chr2_+_36608387 0.35 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr4_+_69262318 0.35 ENSDART00000188841
si:ch211-209j12.6
si:ch211-209j12.6
chr21_-_44081540 0.34 ENSDART00000130833
FO704810.1

chr17_+_14711765 0.34 ENSDART00000012889
cx28.6
connexin 28.6
chr8_-_46457233 0.34 ENSDART00000113214
sult1st7
sulfotransferase family 1, cytosolic sulfotransferase 7
chr1_-_56717813 0.34 ENSDART00000159196
FO681314.1

chr17_-_6600899 0.33 ENSDART00000154074
ENSDART00000180912
ANKRD66
si:ch211-189e2.2
chr19_-_5125663 0.33 ENSDART00000005547
ENSDART00000132642
gnb3b
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr5_-_26181863 0.32 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr14_+_46313396 0.31 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr3_-_34054081 0.31 ENSDART00000151590
ighv1-2
immunoglobulin heavy variable 1-2
chr17_-_6599484 0.31 ENSDART00000156927
ANKRD66
si:ch211-189e2.2
chr6_+_17789481 0.31 ENSDART00000190768
CR376861.1

chr12_+_19030391 0.30 ENSDART00000153927
si:ch73-139e5.2
si:ch73-139e5.2
chr24_-_26485098 0.30 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr14_+_26439227 0.30 ENSDART00000054183
gpr137
G protein-coupled receptor 137
chr2_-_45510699 0.30 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr16_+_5926520 0.29 ENSDART00000162229
ulk4
unc-51 like kinase 4
chr17_-_44402713 0.29 ENSDART00000190343
BX548045.2

chr7_+_38380135 0.28 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr17_-_20228610 0.28 ENSDART00000125758
ebf3b
early B cell factor 3b
chr8_-_23884301 0.28 ENSDART00000185509
ENSDART00000147202
lhfpl5b
LHFPL tetraspan subfamily member 5b
chr8_-_30204650 0.28 ENSDART00000133209
zgc:162939
zgc:162939
chr1_-_55118745 0.28 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr14_-_38872536 0.28 ENSDART00000184315
ENSDART00000127479
gsr
glutathione reductase
chr6_+_12968101 0.27 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr11_+_36665359 0.27 ENSDART00000166144
si:ch211-11c3.9
si:ch211-11c3.9
chr4_-_43070566 0.27 ENSDART00000183779
si:dkey-54j5.2
si:dkey-54j5.2
chr24_-_26484298 0.27 ENSDART00000140647
eif5a
eukaryotic translation initiation factor 5A
chr19_+_43716607 0.27 ENSDART00000133199
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr10_+_32662886 0.26 ENSDART00000099841
rad51c
RAD51 paralog C
chr24_+_13642126 0.26 ENSDART00000126769
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr7_+_8324506 0.25 ENSDART00000168110
si:dkey-185m8.2
si:dkey-185m8.2
chr3_+_53240562 0.25 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr3_-_34068044 0.25 ENSDART00000187926
ighv10-1
immunoglobulin heavy variable 10-1
chr1_+_56755536 0.25 ENSDART00000157727
CABZ01049361.1

chr5_-_57686487 0.25 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr16_+_35535171 0.24 ENSDART00000167001
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr25_+_27405738 0.24 ENSDART00000183266
ENSDART00000115139
pot1
protection of telomeres 1 homolog
chr24_-_21914276 0.24 ENSDART00000128687
c1qtnf9
C1q and TNF related 9
chr12_-_33770299 0.24 ENSDART00000189849
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr6_+_43426599 0.24 ENSDART00000056457
mitfa
microphthalmia-associated transcription factor a
chr20_+_33922339 0.24 ENSDART00000019059
lmx1a
LIM homeobox transcription factor 1, alpha
chr13_+_30912938 0.23 ENSDART00000190003
drgx
dorsal root ganglia homeobox
chr4_+_5392094 0.23 ENSDART00000135122
si:dkey-14d8.20
si:dkey-14d8.20
chr15_+_38071874 0.23 ENSDART00000125770
si:ch73-380l3.5
si:ch73-380l3.5
chr20_+_35445462 0.23 ENSDART00000124497
tdrd6
tudor domain containing 6
chr16_-_21799407 0.23 ENSDART00000123717
FP015862.4

chr22_+_4443689 0.23 ENSDART00000185490
ticam1
toll-like receptor adaptor molecule 1
chr2_-_51500957 0.23 ENSDART00000172481
pigrl3.5
polymeric immunoglobulin receptor-like 3.5
chr19_-_11949996 0.23 ENSDART00000163478
ENSDART00000167299
cpsf1
cleavage and polyadenylation specific factor 1
chr22_+_24770744 0.23 ENSDART00000142882
si:rp71-23d18.4
si:rp71-23d18.4
chr9_+_21243985 0.23 ENSDART00000131586
si:rp71-68n21.12
si:rp71-68n21.12
chr13_-_37636147 0.22 ENSDART00000144065
si:dkey-188i13.8
si:dkey-188i13.8
chr4_+_39055027 0.22 ENSDART00000150397
znf977
zinc finger protein 977
chr1_+_218524 0.22 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr2_-_51512294 0.22 ENSDART00000185287
si:ch211-9d9.8
si:ch211-9d9.8
chr13_-_36761379 0.22 ENSDART00000131534
ENSDART00000029824
map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr10_+_33171501 0.22 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr9_-_21838045 0.22 ENSDART00000147471
acod1
aconitate decarboxylase 1
chr6_-_25371196 0.21 ENSDART00000187291
PKN2 (1 of many)
zgc:153916
chr7_+_9922607 0.21 ENSDART00000184532
ENSDART00000113396
cers3a
ceramide synthase 3a
chr3_-_10751491 0.21 ENSDART00000016351
zgc:112965
zgc:112965
chr4_-_22749553 0.21 ENSDART00000040033
nup107
nucleoporin 107
chr16_-_24703603 0.20 ENSDART00000131167
negaly6
neuromast-expressed gpi-anchored lymphocyte antigen 6
chr19_+_43715911 0.19 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr15_+_31471808 0.19 ENSDART00000110078
or102-3
odorant receptor, family C, subfamily 102, member 3
chr2_+_43864575 0.19 ENSDART00000151951
nlrb5
NOD-like receptor family B, member 5
chr20_-_7547080 0.19 ENSDART00000146135
usp24
ubiquitin specific peptidase 24
chr7_+_67381912 0.19 ENSDART00000167564
nfat5b
nuclear factor of activated T cells 5b
chr9_-_2936017 0.19 ENSDART00000102823
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr5_+_38743644 0.19 ENSDART00000137658
si:dkey-58f10.6
si:dkey-58f10.6
chr17_-_32863250 0.19 ENSDART00000167292
prox1a
prospero homeobox 1a
chr16_+_42464613 0.19 ENSDART00000162454
si:ch211-215k15.4
si:ch211-215k15.4
chr5_-_23715027 0.19 ENSDART00000139020
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr1_-_35695614 0.19 ENSDART00000133813
ENSDART00000145291
ENSDART00000176451
si:dkey-27h10.2
si:dkey-27h10.2
chr12_+_17865374 0.18 ENSDART00000169019
tmem130
transmembrane protein 130
chr23_-_35491587 0.18 ENSDART00000153794
fam110c
family with sequence similarity 110, member C
chr14_+_9462726 0.18 ENSDART00000063559
rell2
RELT-like 2
chr20_+_27749133 0.18 ENSDART00000089013
vrtn
vertebrae development associated
chr21_+_12056934 0.18 ENSDART00000125380
zgc:162344
zgc:162344
chr14_+_16036139 0.18 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr13_-_38088627 0.18 ENSDART00000175268
CT027676.1

chr5_-_26834511 0.18 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
si:ch211-102c2.4
chr5_+_38680061 0.18 ENSDART00000143259
si:dkey-58f10.11
si:dkey-58f10.11
chr16_-_32204470 0.18 ENSDART00000143928
rwdd1
RWD domain containing 1
chr3_-_5644028 0.17 ENSDART00000019957
ddx39ab
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr13_+_30912385 0.17 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr14_-_970853 0.17 ENSDART00000130801
acsl1b
acyl-CoA synthetase long chain family member 1b
chr19_-_41404870 0.17 ENSDART00000167772
sem1
SEM1, 26S proteasome complex subunit
chr11_+_16138065 0.17 ENSDART00000188616
pimr204
Pim proto-oncogene, serine/threonine kinase, related 204
chr6_-_39765546 0.17 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr17_+_2727807 0.16 ENSDART00000178759
kcnk10b
potassium channel, subfamily K, member 10b
chr21_-_16113477 0.16 ENSDART00000147588
cyb561a3b
cytochrome b561 family, member A3b
chr16_-_24703855 0.16 ENSDART00000182422
negaly6
neuromast-expressed gpi-anchored lymphocyte antigen 6
chr18_+_20034023 0.16 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr16_-_41488023 0.16 ENSDART00000169312
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr16_-_41487589 0.16 ENSDART00000188115
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr4_-_41209037 0.16 ENSDART00000151948
si:ch211-73m21.1
si:ch211-73m21.1
chr9_-_11560110 0.16 ENSDART00000176941
cryba2b
crystallin, beta A2b
chr21_-_16113799 0.16 ENSDART00000187848
cyb561a3b
cytochrome b561 family, member A3b
chr3_+_52078798 0.16 ENSDART00000156882
si:dkey-88e12.3
si:dkey-88e12.3
chr21_+_21621042 0.16 ENSDART00000134907
tgfb1b
transforming growth factor, beta 1b
chr14_+_30910114 0.15 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr3_-_18675688 0.15 ENSDART00000048218
slc5a11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr25_-_16160494 0.15 ENSDART00000146880
si:dkey-80c24.4
si:dkey-80c24.4
chr6_-_1591002 0.15 ENSDART00000087039
zgc:123305
zgc:123305
chr4_-_71110826 0.15 ENSDART00000167431
si:dkeyp-80d11.1
si:dkeyp-80d11.1
chr16_+_26846495 0.15 ENSDART00000078124
trim35-29
tripartite motif containing 35-29
chr15_+_11644866 0.15 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr20_+_9128256 0.14 ENSDART00000163883
ENSDART00000183072
ENSDART00000187276
bpnt1
bisphosphate nucleotidase 1
chr25_+_35058088 0.14 ENSDART00000156838
zgc:112234
zgc:112234
chr12_-_44010532 0.14 ENSDART00000183875
si:ch211-182p11.1
si:ch211-182p11.1
chr18_-_33254039 0.14 ENSDART00000099130
si:ch211-229c8.4
si:ch211-229c8.4
chr13_+_8677166 0.14 ENSDART00000181016
ENSDART00000135028
prop1
PROP paired-like homeobox 1
chr12_-_17479078 0.13 ENSDART00000079115
papss2b
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr2_-_6112862 0.13 ENSDART00000164269
prdx1
peroxiredoxin 1
chr15_-_37779978 0.13 ENSDART00000157202
si:dkey-42l23.3
si:dkey-42l23.3
chr2_+_36939749 0.13 ENSDART00000005382
gadd45bb
growth arrest and DNA-damage-inducible, beta b
chr11_+_583725 0.13 ENSDART00000189415
mkrn2os.2
MKRN2 opposite strand, tandem duplicate 2
chr25_-_15268443 0.12 ENSDART00000151827
ccdc73
coiled-coil domain containing 73
chr4_-_36139585 0.12 ENSDART00000132071
znf992
zinc finger protein 992
chr9_-_11560427 0.12 ENSDART00000127942
ENSDART00000061442
cryba2b
crystallin, beta A2b
chr12_-_4916969 0.12 ENSDART00000161680
ifnphi4
interferon phi 4
chr12_-_5998898 0.12 ENSDART00000142659
ENSDART00000004896
kat7b
K(lysine) acetyltransferase 7b
chr4_+_35901451 0.12 ENSDART00000131142
znf1088
zinc finger protein 1088

Network of associatons between targets according to the STRING database.

First level regulatory network of sox14+sox14-1+sox21a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0044878 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878) regulation of lymphocyte apoptotic process(GO:0070228)
0.2 0.5 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.6 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.7 GO:0030826 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.3 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.6 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 0.7 GO:0006833 water transport(GO:0006833)
0.1 3.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.3 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.9 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.2 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.9 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0000730 DNA recombinase assembly(GO:0000730)
0.0 0.5 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0030801 activation of adenylate cyclase activity(GO:0007190) positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of cyclase activity(GO:0031281) positive regulation of adenylate cyclase activity(GO:0045762) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.0 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.2 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.0 0.8 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0043388 cytidine to uridine editing(GO:0016554) positive regulation of DNA binding(GO:0043388)
0.0 1.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:0003313 heart rudiment development(GO:0003313)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 2.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.5 GO:0001843 neural tube closure(GO:0001843)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.1 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.1 GO:0071459 mitotic metaphase plate congression(GO:0007080) protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.3 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0008352 katanin complex(GO:0008352)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0022626 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2 0.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.5 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.3 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.3 GO:0008252 nucleotidase activity(GO:0008252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase