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PRJNA207719: Tissue specific transcriptome profiling

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Results for sox17

Z-value: 0.95

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Transcription factors associated with sox17

Gene Symbol Gene ID Gene Info
sox17
ENSDARG00000101717 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox17dr11_v1_chr7_-_58776400_587764000.247.0e-01Click!

Activity profile of sox17 motif

Sorted Z-values of sox17 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_11493236 0.64 ENSDART00000002691
tspan7b
tetraspanin 7b
chr4_-_14328997 0.48 ENSDART00000091151
nell2b
neural EGFL like 2b
chr5_-_20678300 0.42 ENSDART00000088639
wscd2
WSC domain containing 2
chr24_-_38079261 0.41 ENSDART00000105662
crp1
C-reactive protein 1
chr1_-_12278056 0.39 ENSDART00000139336
ENSDART00000137463
cplx2l
complexin 2, like
chr1_-_42779075 0.39 ENSDART00000133917
lrrtm1
leucine rich repeat transmembrane neuronal 1
chr10_+_4235998 0.38 ENSDART00000169328
plppr1
phospholipid phosphatase related 1
chr15_-_33896159 0.36 ENSDART00000159791
mag
myelin associated glycoprotein
chr2_+_3472832 0.33 ENSDART00000115278
cx47.1
connexin 47.1
chr10_-_2522588 0.33 ENSDART00000081926
CU856539.1

chr25_-_1720736 0.33 ENSDART00000097256
SLC6A13
solute carrier family 6 member 13
chr20_+_40457599 0.32 ENSDART00000017553
serinc1
serine incorporator 1
chr2_-_12502495 0.31 ENSDART00000186781
dpp6b
dipeptidyl-peptidase 6b
chr16_-_28658341 0.31 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr11_+_35364445 0.31 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr1_+_44800298 0.31 ENSDART00000073712
ENSDART00000187054
tmem187
transmembrane protein 187
chr8_+_6967108 0.31 ENSDART00000004588
asic1a
acid-sensing (proton-gated) ion channel 1a
chr2_+_26240631 0.30 ENSDART00000129895
palm1b
paralemmin 1b
chr5_-_26323137 0.30 ENSDART00000133823
arvcfb
ARVCF, delta catenin family member b
chr21_+_33503835 0.30 ENSDART00000125658
clint1b
clathrin interactor 1b
chr1_+_6817292 0.30 ENSDART00000145822
ENSDART00000092118
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr9_-_16218097 0.30 ENSDART00000190503
myo1b
myosin IB
chr7_+_23495986 0.29 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr21_-_7178348 0.29 ENSDART00000187467
fam69b
family with sequence similarity 69, member B
chr7_-_40122139 0.29 ENSDART00000173982
si:ch73-174h16.5
si:ch73-174h16.5
chr16_+_43152727 0.29 ENSDART00000125590
ENSDART00000154493
adam22
ADAM metallopeptidase domain 22
chr12_+_11080776 0.29 ENSDART00000079336
raraa
retinoic acid receptor, alpha a
chr17_+_50127648 0.29 ENSDART00000156460
galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr17_+_25289431 0.28 ENSDART00000161002
kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr19_-_41213718 0.28 ENSDART00000077121
pdk4
pyruvate dehydrogenase kinase, isozyme 4
chr20_-_45060241 0.28 ENSDART00000185227
klhl29
kelch-like family member 29
chr22_+_14051245 0.28 ENSDART00000043711
ENSDART00000164259
aox6
aldehyde oxidase 6
chr23_-_35694461 0.28 ENSDART00000185884
tuba1c
tubulin, alpha 1c
chr25_-_7686201 0.28 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
si:ch211-286c4.6
chr20_-_20932760 0.28 ENSDART00000152415
ENSDART00000039907
btbd6b
BTB (POZ) domain containing 6b
chr6_-_7842078 0.27 ENSDART00000065507
plppr2b
phospholipid phosphatase related 2b
chr7_-_24373662 0.27 ENSDART00000173865
PTGR1 (1 of many)
si:dkey-11k2.7
chr17_-_33289304 0.27 ENSDART00000135118
ENSDART00000040346
efr3ba
EFR3 homolog Ba (S. cerevisiae)
chr10_-_22845485 0.27 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr21_-_39628771 0.27 ENSDART00000183995
aldocb
aldolase C, fructose-bisphosphate, b
chr20_+_25911342 0.27 ENSDART00000146004
ttbk2b
tau tubulin kinase 2b
chr11_-_25213651 0.26 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr5_+_1278092 0.26 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr15_-_33904831 0.25 ENSDART00000164333
ENSDART00000165404
mag
myelin associated glycoprotein
chr3_-_18711288 0.25 ENSDART00000183885
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr3_+_15279016 0.25 ENSDART00000182005
asphd1
aspartate beta-hydroxylase domain containing 1
chr20_-_45062514 0.25 ENSDART00000183529
ENSDART00000182955
klhl29
kelch-like family member 29
chr14_-_9350364 0.24 ENSDART00000164451
fam46d
family with sequence similarity 46, member D
chr21_+_18353703 0.24 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
si:ch73-287m6.1
chr22_+_12361317 0.24 ENSDART00000189963
ENSDART00000159614
r3hdm1
R3H domain containing 1
chr19_-_15397946 0.24 ENSDART00000143480
hivep3a
human immunodeficiency virus type I enhancer binding protein 3a
chr24_-_14712427 0.24 ENSDART00000176316
jph1a
junctophilin 1a
chr11_-_8320868 0.24 ENSDART00000160570
si:ch211-247n2.1
si:ch211-247n2.1
chr12_+_9342502 0.24 ENSDART00000152808
kcnh6b
potassium voltage-gated channel, subfamily H (eag-related), member 6b
chr3_-_29688370 0.23 ENSDART00000151147
ENSDART00000151679
si:ch73-233k15.2
si:ch73-233k15.2
chr5_-_63109232 0.23 ENSDART00000115128
usp2b
ubiquitin specific peptidase 2b
chr22_+_12361489 0.23 ENSDART00000182483
r3hdm1
R3H domain containing 1
chr5_-_68495967 0.23 ENSDART00000188107
ephb4a
eph receptor B4a
chr22_+_14051894 0.23 ENSDART00000142548
aox6
aldehyde oxidase 6
chr11_-_41996957 0.23 ENSDART00000055706
her15.2
hairy and enhancer of split-related 15, tandem duplicate 2
chr11_-_29833698 0.23 ENSDART00000079149
xk
X-linked Kx blood group (McLeod syndrome)
chr8_+_13368150 0.22 ENSDART00000114699
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr1_-_44704261 0.22 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr17_-_19963718 0.22 ENSDART00000154251
chrm3a
cholinergic receptor, muscarinic 3a
chr19_-_7406933 0.22 ENSDART00000151137
oxr1b
oxidation resistance 1b
chr23_+_34321237 0.22 ENSDART00000173272
plxna1a
plexin A1a
chr15_+_22267847 0.22 ENSDART00000110665
spa17
sperm autoantigenic protein 17
chr22_-_26236188 0.21 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
c3b.1
complement component c3b, tandem duplicate 1
chr16_+_5184402 0.21 ENSDART00000156685
soga3a
SOGA family member 3a
chr6_-_43092175 0.21 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr5_+_36870737 0.21 ENSDART00000145182
slc8a2a
solute carrier family 8 (sodium/calcium exchanger), member 2a
chr17_+_51499789 0.21 ENSDART00000187701
CABZ01067581.1

chr15_+_16521785 0.21 ENSDART00000062191
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr23_-_10048533 0.21 ENSDART00000166663
plxnb1a
plexin b1a
chr21_-_12036134 0.21 ENSDART00000031658
tpgs2
tubulin polyglutamylase complex subunit 2
chr16_+_50741154 0.21 ENSDART00000101627
IGLON5
zgc:110372
chr14_-_41285392 0.20 ENSDART00000147389
tmem35
transmembrane protein 35
chr10_-_3258073 0.20 ENSDART00000113162
pi4kaa
phosphatidylinositol 4-kinase, catalytic, alpha a
chr20_-_31238313 0.20 ENSDART00000028471
hpcal1
hippocalcin-like 1
chr6_+_54498220 0.20 ENSDART00000103282
si:ch211-233f11.5
si:ch211-233f11.5
chr11_+_15931188 0.20 ENSDART00000165768
ENSDART00000081098
draxin
dorsal inhibitory axon guidance protein
chr9_+_34641237 0.20 ENSDART00000133996
shox
short stature homeobox
chr7_-_34329527 0.20 ENSDART00000173454
madd
MAP-kinase activating death domain
chr3_+_18097700 0.20 ENSDART00000021634
wfikkn2a
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr14_-_17563773 0.20 ENSDART00000082667
fgfrl1a
fibroblast growth factor receptor like 1a
chr1_+_53321878 0.19 ENSDART00000143909
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr16_-_8927425 0.19 ENSDART00000000382
triob
trio Rho guanine nucleotide exchange factor b
chr1_-_39977551 0.19 ENSDART00000139354
stox2a
storkhead box 2a
chr21_-_2248239 0.19 ENSDART00000169448
si:ch73-299h12.1
si:ch73-299h12.1
chr7_-_18601206 0.19 ENSDART00000111636
DTX4
si:ch211-119e14.2
chr2_-_9260002 0.19 ENSDART00000057299
st6galnac5a
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
chr1_-_656693 0.19 ENSDART00000170483
ENSDART00000166786
appa
amyloid beta (A4) precursor protein a
chr3_+_18437397 0.19 ENSDART00000136243
ENSDART00000184882
ENSDART00000135470
tbc1d16
TBC1 domain family, member 16
chr17_-_6399920 0.19 ENSDART00000022010
hivep2b
human immunodeficiency virus type I enhancer binding protein 2b
chr14_+_6954579 0.19 ENSDART00000060998
nme5
NME/NM23 family member 5
chr3_-_39190317 0.18 ENSDART00000013167
retsat
retinol saturase (all-trans-retinol 13,14-reductase)
chr24_-_25673405 0.18 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
cnksr2a
connector enhancer of kinase suppressor of Ras 2a
chr1_-_23110740 0.18 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr9_-_46276626 0.18 ENSDART00000165238
hdac4
histone deacetylase 4
chr12_-_30032188 0.18 ENSDART00000042514
atrnl1b
attractin-like 1b
chr14_+_29609245 0.18 ENSDART00000043058
TENM2
si:dkey-34l15.2
chr19_+_42886413 0.18 ENSDART00000151298
arpp21
cAMP-regulated phosphoprotein, 21
chr20_+_18945057 0.18 ENSDART00000035447
mtmr9
myotubularin related protein 9
chr7_+_22688781 0.17 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr21_+_21791343 0.17 ENSDART00000151654
neu3.1
sialidase 3 (membrane sialidase), tandem duplicate 1
chr6_-_12314475 0.17 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr14_-_28534563 0.17 ENSDART00000054088
zgc:113364
zgc:113364
chr15_-_30815826 0.17 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr2_-_10062575 0.17 ENSDART00000091726
fam78ba
family with sequence similarity 78, member B a
chr23_+_18779043 0.17 ENSDART00000158267
emp3b
epithelial membrane protein 3b
chr17_+_24222190 0.17 ENSDART00000181698
ENSDART00000189411
ehbp1
EH domain binding protein 1
chr18_+_30915348 0.17 ENSDART00000139398
mthfsd
methenyltetrahydrofolate synthetase domain containing
chr1_-_46981134 0.16 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr18_-_16181952 0.16 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr7_+_34297271 0.16 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_-_31103906 0.16 ENSDART00000189099
ENSDART00000121527
ENSDART00000185635
ENSDART00000183754
tcf7l2
transcription factor 7 like 2
chr1_+_49878000 0.16 ENSDART00000047876
lef1
lymphoid enhancer-binding factor 1
chr9_-_30346279 0.16 ENSDART00000089488
sytl5
synaptotagmin-like 5
chr11_+_6152643 0.16 ENSDART00000012789
slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr2_-_42843797 0.16 ENSDART00000137913
adcy8
adenylate cyclase 8 (brain)
chr10_+_33627429 0.16 ENSDART00000138542
b3glctb
beta 3-glucosyltransferase b
chr16_-_31598771 0.16 ENSDART00000016386
tg
thyroglobulin
chr5_-_33606729 0.16 ENSDART00000137073
si:dkey-34e4.1
si:dkey-34e4.1
chr6_-_35472923 0.16 ENSDART00000185907
rgs8
regulator of G protein signaling 8
chr25_+_23358924 0.16 ENSDART00000156965
osbpl5
oxysterol binding protein-like 5
chr19_-_25114701 0.15 ENSDART00000149035
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr18_+_38807239 0.15 ENSDART00000184332
fam214a
family with sequence similarity 214, member A
chr5_+_45990046 0.15 ENSDART00000084024
sv2c
synaptic vesicle glycoprotein 2C
chr17_-_15382704 0.15 ENSDART00000005313
zgc:85722
zgc:85722
chr6_+_30091811 0.15 ENSDART00000088403
meltf
melanotransferrin
chr11_-_36341189 0.15 ENSDART00000159752
sort1a
sortilin 1a
chr2_+_51818039 0.15 ENSDART00000170353
acvr2bb
activin A receptor type 2Bb
chr8_-_43120844 0.15 ENSDART00000193242
ccdc92
coiled-coil domain containing 92
chr5_-_54790923 0.15 ENSDART00000176835
pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_14551077 0.15 ENSDART00000188717
FO704673.1

chr24_-_12832499 0.15 ENSDART00000182027
ENSDART00000039312
ipo4
importin 4
chr17_-_43552894 0.15 ENSDART00000181226
ENSDART00000188125
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr3_-_40976288 0.14 ENSDART00000193553
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr17_+_51520073 0.14 ENSDART00000189646
ENSDART00000170951
ENSDART00000189492
pxdn
peroxidasin
chr13_+_41917606 0.14 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr1_-_54938137 0.14 ENSDART00000147212
crtac1a
cartilage acidic protein 1a
chr14_+_25817628 0.14 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr25_+_20140926 0.14 ENSDART00000121989
cald1b
caldesmon 1b
chr5_-_5243079 0.14 ENSDART00000130576
ENSDART00000164377
mvb12ba
multivesicular body subunit 12Ba
chr15_+_28368823 0.14 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr9_+_31534601 0.14 ENSDART00000133094
si:ch211-168k14.2
si:ch211-168k14.2
chr11_-_472547 0.14 ENSDART00000005923
zgc:77375
zgc:77375
chr1_-_49649122 0.14 ENSDART00000134399
slkb
STE20-like kinase b
chr3_+_12334509 0.14 ENSDART00000165796
glis2b
GLIS family zinc finger 2b
chr22_-_26175237 0.14 ENSDART00000108737
c3b.2
complement component c3b, tandem duplicate 2
chr23_-_16960972 0.14 ENSDART00000142546
cdc42l2
cell division cycle 42 like 2
chr25_+_26844028 0.14 ENSDART00000127274
ENSDART00000156179
sema7a
semaphorin 7A
chr4_+_9030609 0.13 ENSDART00000154399
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr7_+_65876335 0.13 ENSDART00000150143
tead1b
TEA domain family member 1b
chr11_+_25259058 0.13 ENSDART00000154109
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr19_-_36234185 0.13 ENSDART00000186003
csmd2
CUB and Sushi multiple domains 2
chr12_-_41662327 0.13 ENSDART00000191602
ENSDART00000170423
jakmip3
Janus kinase and microtubule interacting protein 3
chr11_-_27537593 0.13 ENSDART00000173444
ENSDART00000172895
ENSDART00000088177
ptpdc1a
protein tyrosine phosphatase domain containing 1a
chr25_+_25123385 0.13 ENSDART00000163892
ldha
lactate dehydrogenase A4
chr3_+_56366395 0.13 ENSDART00000154367
cacng5b
calcium channel, voltage-dependent, gamma subunit 5b
chr7_-_35314347 0.13 ENSDART00000005053
slc12a4
solute carrier family 12 (potassium/chloride transporter), member 4
chr14_+_3411771 0.13 ENSDART00000164778
trpc3
transient receptor potential cation channel, subfamily C, member 3
chr15_+_28368644 0.13 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr19_+_32947910 0.12 ENSDART00000052091
atp6v1c1b
ATPase H+ transporting V1 subunit C1b
chr4_-_42074960 0.12 ENSDART00000164406
zgc:174696
zgc:174696
chr11_-_36341028 0.12 ENSDART00000146093
sort1a
sortilin 1a
chr14_-_13048355 0.12 ENSDART00000166434
si:dkey-35h6.1
si:dkey-35h6.1
chr12_-_16452200 0.12 ENSDART00000037601
rpp30
ribonuclease P/MRP 30 subunit
chr14_+_11909966 0.12 ENSDART00000171829
frmpd3
FERM and PDZ domain containing 3
chr1_+_29281764 0.12 ENSDART00000112106
fam155a
family with sequence similarity 155, member A
chr21_-_37972412 0.12 ENSDART00000186315
ripply1
ripply transcriptional repressor 1
chr18_+_17534627 0.12 ENSDART00000061007
mt2
metallothionein 2
chr6_-_44402358 0.12 ENSDART00000193007
ENSDART00000193603
pdzrn3b
PDZ domain containing RING finger 3b
chr23_+_42346799 0.12 ENSDART00000159985
ENSDART00000172144
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr16_-_30826712 0.12 ENSDART00000122474
ptk2ab
protein tyrosine kinase 2ab
chr14_-_46113321 0.12 ENSDART00000169040
ENSDART00000161475
ENSDART00000124925
si:ch211-235e9.8
si:ch211-235e9.8
chr8_+_24747865 0.12 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr25_+_19201231 0.12 ENSDART00000067323
hapln3
hyaluronan and proteoglycan link protein 3
chr13_+_2617555 0.12 ENSDART00000162208
plpp4
phospholipid phosphatase 4
chr21_-_39546737 0.11 ENSDART00000006971
sept4a
septin 4a
chr19_+_42432625 0.11 ENSDART00000076938
pogza
pogo transposable element derived with ZNF domain a
chr15_+_1765988 0.11 ENSDART00000159032
cul3b
cullin 3b
chr25_-_21280584 0.11 ENSDART00000143644
tmem60
transmembrane protein 60
chr13_-_10730056 0.11 ENSDART00000126725
ppm1ba
protein phosphatase, Mg2+/Mn2+ dependent, 1Ba
chr3_-_40976463 0.11 ENSDART00000128450
ENSDART00000018676
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr14_-_30897177 0.11 ENSDART00000087918
slc7a3b
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b
chr14_+_36246726 0.11 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr24_+_26997798 0.11 ENSDART00000089506
larp4b
La ribonucleoprotein domain family, member 4B
chr21_-_20381481 0.11 ENSDART00000115236
atp5mea
ATP synthase membrane subunit ea
chr25_-_13490744 0.11 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr11_-_45385602 0.11 ENSDART00000166691
trappc10
trafficking protein particle complex 10
chr13_+_40034176 0.11 ENSDART00000189797
golga7bb
golgin A7 family, member Bb
chr21_+_41511469 0.11 ENSDART00000172563
stc2b
stanniocalcin 2b
chr17_-_5769196 0.11 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr11_-_1948784 0.11 ENSDART00000082475
nr1d4b
nuclear receptor subfamily 1, group D, member 4b
chr5_-_37871526 0.11 ENSDART00000136450
arhgap35b
Rho GTPase activating protein 35b
chr16_-_27138478 0.11 ENSDART00000147438
tmem245
transmembrane protein 245
chr21_+_39963851 0.10 ENSDART00000144435
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr10_-_34981219 0.10 ENSDART00000132823
smad9
SMAD family member 9
chr16_-_52736549 0.10 ENSDART00000146607
azin1a
antizyme inhibitor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.1 0.2 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.1 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0019068 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0 0.2 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.1 GO:0010759 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.4 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.1 GO:0071294 cellular response to cadmium ion(GO:0071276) cellular response to zinc ion(GO:0071294)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0044003 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) distal tubule morphogenesis(GO:0072156) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.0 GO:0010265 SCF complex assembly(GO:0010265)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.2 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.3 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters