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PRJNA207719: Tissue specific transcriptome profiling

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Results for sox19b+sox3

Z-value: 0.54

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Transcription factors associated with sox19b+sox3

Gene Symbol Gene ID Gene Info
sox19b
ENSDARG00000040266 SRY-box transcription factor 19b
sox3
ENSDARG00000053569 SRY-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox19bdr11_v1_chr7_-_26497947_26497947-0.932.0e-02Click!
sox3dr11_v1_chr14_-_32744464_32744464-0.781.2e-01Click!

Activity profile of sox19b+sox3 motif

Sorted Z-values of sox19b+sox3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_14280598 0.42 ENSDART00000163033
si:ch211-262i1.3
si:ch211-262i1.3
chr2_-_24269911 0.38 ENSDART00000099532
myh7
myosin heavy chain 7
chr23_+_20110086 0.36 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr2_-_24270062 0.36 ENSDART00000192445
myh7
myosin heavy chain 7
chr9_-_23891102 0.35 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18
chr24_-_40668208 0.34 ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr5_-_46505691 0.34 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hapln1a
hyaluronan and proteoglycan link protein 1a
chr19_+_46113828 0.34 ENSDART00000159331
ENSDART00000161826
rbm24a
RNA binding motif protein 24a
chr20_-_33976305 0.34 ENSDART00000111022
sele
selectin E
chr10_+_33171501 0.33 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr23_-_10175898 0.30 ENSDART00000146185
krt5
keratin 5
chr11_+_10548171 0.29 ENSDART00000191497
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr23_+_5499307 0.29 ENSDART00000170361
tead3a
TEA domain family member 3 a
chr3_+_3545825 0.29 ENSDART00000109060
CR589947.1

chr6_+_54576520 0.28 ENSDART00000093199
ENSDART00000127519
ENSDART00000157142
tead3b
TEA domain family member 3 b
chr9_+_23770666 0.27 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr12_-_30777743 0.27 ENSDART00000148888
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr25_+_35502552 0.27 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr20_+_40237441 0.27 ENSDART00000168928
si:ch211-199i15.5
si:ch211-199i15.5
chr16_+_29586468 0.26 ENSDART00000148926
mcl1b
MCL1, BCL2 family apoptosis regulator b
chr16_-_33104944 0.26 ENSDART00000151943
pnrc2
proline-rich nuclear receptor coactivator 2
chr15_-_43164591 0.26 ENSDART00000171305
ap1s3a
adaptor-related protein complex 1, sigma 3 subunit, a
chr22_-_10541372 0.26 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr8_-_18537866 0.26 ENSDART00000148802
ENSDART00000148962
ENSDART00000149506
nexn
nexilin (F actin binding protein)
chr25_+_14109626 0.26 ENSDART00000109883
actc1c
actin, alpha, cardiac muscle 1c
chr23_-_31506854 0.26 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
eya4
EYA transcriptional coactivator and phosphatase 4
chr22_+_19220459 0.25 ENSDART00000163070
si:dkey-21e2.7
si:dkey-21e2.7
chr14_+_11457500 0.25 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr19_+_20778011 0.25 ENSDART00000024208
nutf2l
nuclear transport factor 2, like
chr7_+_35268880 0.25 ENSDART00000182231
dpep2
dipeptidase 2
chr12_-_36045283 0.25 ENSDART00000160646
gprc5c
G protein-coupled receptor, class C, group 5, member C
chr19_+_24488403 0.25 ENSDART00000052421
txnipa
thioredoxin interacting protein a
chr15_-_37829160 0.25 ENSDART00000099425
ctrl
chymotrypsin-like
chr25_-_22187397 0.24 ENSDART00000123211
ENSDART00000139110
pkp3a
plakophilin 3a
chr7_-_53117131 0.24 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr13_+_30225262 0.24 ENSDART00000141945
rps24
ribosomal protein S24
chr7_-_6459481 0.23 ENSDART00000173158
zgc:112234
zgc:112234
chr4_+_18843015 0.23 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
bik
BCL2 interacting killer
chr17_+_25849332 0.23 ENSDART00000191994
acss1
acyl-CoA synthetase short chain family member 1
chr9_-_21912227 0.23 ENSDART00000145576
lmo7a
LIM domain 7a
chr3_-_34069637 0.23 ENSDART00000151588
ighv9-1
immunoglobulin heavy variable 9-1
chr23_-_5683147 0.22 ENSDART00000102766
ENSDART00000067351
tnnt2a
troponin T type 2a (cardiac)
chr10_+_9550419 0.22 ENSDART00000064977
si:ch211-243g18.2
si:ch211-243g18.2
chr3_-_57425961 0.22 ENSDART00000033716
socs3a
suppressor of cytokine signaling 3a
chr13_+_22675802 0.22 ENSDART00000145538
ENSDART00000143312
zgc:193505
zgc:193505
chr16_-_32975951 0.22 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr2_-_37103622 0.22 ENSDART00000137849
zgc:101744
zgc:101744
chr18_-_6633984 0.22 ENSDART00000185241
tnni1c
troponin I, skeletal, slow c
chr6_+_52804267 0.21 ENSDART00000065681
matn4
matrilin 4
chr18_+_8912113 0.21 ENSDART00000147467
tmem243a
transmembrane protein 243, mitochondrial a
chr18_-_6634424 0.21 ENSDART00000062423
ENSDART00000179955
tnni1c
troponin I, skeletal, slow c
chr6_+_45932276 0.21 ENSDART00000103491
rbp7b
retinol binding protein 7b, cellular
chr23_-_23256726 0.21 ENSDART00000131353
si:dkey-98j1.5
si:dkey-98j1.5
chr21_+_19368720 0.21 ENSDART00000187759
ENSDART00000185829
ENSDART00000158471
ENSDART00000168728
btc
betacellulin, epidermal growth factor family member
chr7_+_48761646 0.20 ENSDART00000017467
acana
aggrecan a
chr7_+_39410180 0.20 ENSDART00000168641
CT030188.1

chr16_-_31598771 0.20 ENSDART00000016386
tg
thyroglobulin
chr5_-_7834582 0.20 ENSDART00000162626
ENSDART00000157661
pdlim5a
PDZ and LIM domain 5a
chr11_-_10659195 0.20 ENSDART00000115255
mcf2l2
MCF.2 cell line derived transforming sequence-like 2
chr14_-_8080416 0.20 ENSDART00000045109
zgc:92242
zgc:92242
chr16_+_35535375 0.20 ENSDART00000171675
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr9_-_50001606 0.20 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr7_+_48761875 0.20 ENSDART00000003690
acana
aggrecan a
chr22_+_661711 0.19 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr20_+_23498255 0.19 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr21_+_11776328 0.19 ENSDART00000134469
ENSDART00000081646
glrx
glutaredoxin (thioltransferase)
chr12_-_30777540 0.19 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr18_+_8912710 0.19 ENSDART00000142866
tmem243a
transmembrane protein 243, mitochondrial a
chr23_+_36144487 0.19 ENSDART00000082473
hoxc3a
homeobox C3a
chr5_-_37117778 0.19 ENSDART00000149138
il13ra2
interleukin 13 receptor, alpha 2
chr3_+_22273123 0.19 ENSDART00000044157
scn4ab
sodium channel, voltage-gated, type IV, alpha, b
chr9_+_13986427 0.19 ENSDART00000147200
cd28
CD28 molecule
chr4_-_16354292 0.19 ENSDART00000139919
lum
lumican
chr16_+_25245857 0.18 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr21_-_11646878 0.18 ENSDART00000162426
ENSDART00000135937
ENSDART00000131448
ENSDART00000148097
ENSDART00000133443
cast
calpastatin
chr3_-_50139860 0.18 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr8_-_43750062 0.18 ENSDART00000142243
ulk1a
unc-51 like autophagy activating kinase 1a
chr11_-_28050559 0.18 ENSDART00000136859
ece1
endothelin converting enzyme 1
chr19_+_47394270 0.18 ENSDART00000171281
psmb2
proteasome subunit beta 2
chr19_+_43119698 0.18 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr3_+_29640996 0.18 ENSDART00000011052
eif3d
eukaryotic translation initiation factor 3, subunit D
chr14_+_38786298 0.17 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr7_+_39410393 0.17 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr3_+_8290595 0.17 ENSDART00000142691
trim35-10
tripartite motif containing 35-10
chr15_-_3736149 0.17 ENSDART00000182986
lpar6a
lysophosphatidic acid receptor 6a
chr7_+_39444843 0.17 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
tnnt3b
troponin T type 3b (skeletal, fast)
chr13_+_46941930 0.17 ENSDART00000056962
fbxo5
F-box protein 5
chr6_-_13206255 0.17 ENSDART00000065373
eef1b2
eukaryotic translation elongation factor 1 beta 2
chr12_-_22524388 0.17 ENSDART00000020942
shbg
sex hormone-binding globulin
chr17_+_45405821 0.17 ENSDART00000189482
ENSDART00000177422
tagapa
T cell activation RhoGTPase activating protein a
chr23_-_30045661 0.17 ENSDART00000122239
ENSDART00000103480
ccdc187
coiled-coil domain containing 187
chr23_-_21515182 0.17 ENSDART00000142000
rnf207b
ring finger protein 207b
chr5_+_15203421 0.17 ENSDART00000040826
tbx1
T-box 1
chr18_+_8912536 0.16 ENSDART00000134827
ENSDART00000061904
tmem243a
transmembrane protein 243, mitochondrial a
chr5_+_4564233 0.16 ENSDART00000193435
CABZ01058647.1

chr5_-_55560937 0.16 ENSDART00000148436
gna14
guanine nucleotide binding protein (G protein), alpha 14
chr2_-_51794472 0.16 ENSDART00000186652
BX908782.3

chr23_-_33738945 0.16 ENSDART00000136386
si:ch211-210c8.7
si:ch211-210c8.7
chr23_-_24263474 0.16 ENSDART00000160312
hspb7
heat shock protein family, member 7 (cardiovascular)
chr24_+_20373605 0.16 ENSDART00000112349
plcd1a
phospholipase C, delta 1a
chr15_-_4528326 0.16 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr3_-_45326897 0.16 ENSDART00000086417
il21r.2
interleukin 21 receptor, tandem duplicate 2
chr16_+_21801277 0.16 ENSDART00000088407
trim108
tripartite motif containing 108
chr9_-_43082945 0.16 ENSDART00000142257
ccdc141
coiled-coil domain containing 141
chr15_+_37331585 0.16 ENSDART00000170715
zgc:171592
zgc:171592
chr17_+_30546579 0.16 ENSDART00000154385
nhsl1a
NHS-like 1a
chr21_-_30166097 0.16 ENSDART00000130676
hbegfb
heparin-binding EGF-like growth factor b
chr15_-_36533322 0.16 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr14_-_34059681 0.15 ENSDART00000003993
itk
IL2 inducible T cell kinase
chr23_+_42813415 0.15 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr8_-_28449782 0.15 ENSDART00000062702
cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr6_-_10233538 0.15 ENSDART00000182004
ENSDART00000149237
ENSDART00000148876
xirp2a
xin actin binding repeat containing 2a
chr19_-_19721556 0.15 ENSDART00000165196
evx1
even-skipped homeobox 1
chr12_-_29305533 0.15 ENSDART00000189410
sh2d4bb
SH2 domain containing 4Bb
chr14_+_46313135 0.15 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr23_-_3758637 0.15 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr1_-_33645967 0.15 ENSDART00000192758
cldng
claudin g
chr6_-_52675630 0.15 ENSDART00000083830
sdc4
syndecan 4
chr16_+_26732086 0.15 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr24_+_26932472 0.15 ENSDART00000192288
ENSDART00000079848
tnfsf10
TNF superfamily member 10
chr3_+_12755535 0.15 ENSDART00000161286
cyp2k17
cytochrome P450, family 2, subfamily K, polypeptide17
chr3_+_57820913 0.15 ENSDART00000168101
CU571328.1

chr16_+_35535171 0.15 ENSDART00000167001
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr18_-_38270430 0.15 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr16_-_41762983 0.15 ENSDART00000192936
si:dkey-199f5.8
si:dkey-199f5.8
chr22_-_10121880 0.15 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr16_-_21810668 0.15 ENSDART00000156575
dicp3.3
diverse immunoglobulin domain-containing protein 3.3
chr1_-_25936677 0.15 ENSDART00000146488
ENSDART00000136321
myoz2b
myozenin 2b
chr9_-_14084743 0.14 ENSDART00000056105
fer1l6
fer-1-like family member 6
chr4_-_2380173 0.14 ENSDART00000177727
nap1l1
nucleosome assembly protein 1-like 1
chr18_+_35842933 0.14 ENSDART00000151587
ENSDART00000131121
ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr10_-_25816558 0.14 ENSDART00000017240
postna
periostin, osteoblast specific factor a
chr25_+_31323978 0.14 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr1_-_58111826 0.14 ENSDART00000134949
caspbl
caspase b, like
chr5_+_25762271 0.14 ENSDART00000181323
tmem2
transmembrane protein 2
chr25_-_27843066 0.14 ENSDART00000179684
ENSDART00000186000
ENSDART00000190065
asb15a
ankyrin repeat and SOCS box containing 15a
chr7_+_38380135 0.14 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr3_-_59297532 0.14 ENSDART00000187991
CABZ01053748.1

chr6_-_43677125 0.14 ENSDART00000150128
foxp1b
forkhead box P1b
chr12_-_30523216 0.14 ENSDART00000152896
ENSDART00000153191
plekhs1
pleckstrin homology domain containing, family S member 1
chr10_+_8690936 0.14 ENSDART00000144218
si:dkey-27b3.4
si:dkey-27b3.4
chr24_-_11076400 0.14 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr7_-_8408014 0.14 ENSDART00000112492
zgc:194686
zgc:194686
chr5_-_30984010 0.14 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr25_-_35124576 0.14 ENSDART00000128017
zgc:171759
zgc:171759
chr8_+_14158021 0.14 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr8_-_23884301 0.14 ENSDART00000185509
ENSDART00000147202
lhfpl5b
LHFPL tetraspan subfamily member 5b
chr7_-_7398350 0.14 ENSDART00000012637
zgc:101810
zgc:101810
chr25_-_3470910 0.14 ENSDART00000029067
ENSDART00000186737
hbp1
HMG-box transcription factor 1
chr14_+_30910114 0.14 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr11_+_30295582 0.14 ENSDART00000122424
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr2_-_26596794 0.14 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr5_-_30615901 0.14 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr25_-_12998202 0.14 ENSDART00000171661
ccl39.3
chemokine (C-C motif) ligand 39, duplicate 3
chr24_-_31194847 0.14 ENSDART00000158808
cnn3a
calponin 3, acidic a
chr6_-_9707599 0.14 ENSDART00000039280
fzd7b
frizzled class receptor 7b
chr3_+_3573696 0.14 ENSDART00000169680
CR589947.2

chr3_-_32956808 0.14 ENSDART00000183902
casp6l1
caspase 6, apoptosis-related cysteine peptidase, like 1
chr1_-_47431453 0.14 ENSDART00000101104
gja5b
gap junction protein, alpha 5b
chr11_+_24716837 0.14 ENSDART00000145217
zgc:153953
zgc:153953
chr21_+_27382893 0.14 ENSDART00000005682
actn3a
actinin alpha 3a
chr23_+_24085531 0.14 ENSDART00000139710
ttll10
tubulin tyrosine ligase-like family, member 10
chr7_-_28681724 0.13 ENSDART00000162400
adgrg1
adhesion G protein-coupled receptor G1
chr5_-_41841892 0.13 ENSDART00000167089
si:dkey-65b12.6
si:dkey-65b12.6
chr15_-_29586747 0.13 ENSDART00000076749
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr16_-_26731928 0.13 ENSDART00000135860
rnf41l
ring finger protein 41, like
chr20_+_13533544 0.13 ENSDART00000143115
sytl3
synaptotagmin-like 3
chr2_-_19234329 0.13 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cdc20
cell division cycle 20 homolog
chr4_-_11403811 0.13 ENSDART00000067272
ENSDART00000140018
pimr173
Pim proto-oncogene, serine/threonine kinase, related 173
chr9_-_22831836 0.13 ENSDART00000142585
neb
nebulin
chr7_+_48555400 0.13 ENSDART00000174474
kcnq1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr8_-_28349859 0.13 ENSDART00000062671
tuba8l
tubulin, alpha 8 like
chr1_+_22654875 0.13 ENSDART00000019698
ENSDART00000161874
anxa5b
annexin A5b
chr18_-_38270077 0.13 ENSDART00000185546
caprin1b
cell cycle associated protein 1b
chr6_-_13498745 0.13 ENSDART00000027684
ENSDART00000189438
mylkb
myosin light chain kinase b
chr5_+_38680247 0.13 ENSDART00000132763
si:dkey-58f10.11
si:dkey-58f10.11
chr23_+_42819221 0.13 ENSDART00000180495
myl9a
myosin, light chain 9a, regulatory
chr9_-_24244383 0.13 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr3_-_31258459 0.13 ENSDART00000177928
LO017965.1

chr23_-_3759345 0.13 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr18_+_44649804 0.13 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr1_-_59124505 0.13 ENSDART00000186257
FO203432.1

chr24_-_2947393 0.13 ENSDART00000166661
ENSDART00000147110
tubb6
tubulin, beta 6 class V
chr25_-_3830272 0.13 ENSDART00000055843
cd151
CD151 molecule
chr11_+_29965822 0.13 ENSDART00000127049
il1fma
interleukin-1 family member A
chr23_-_19715799 0.13 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
rpl10
ribosomal protein L10
chr16_-_31976269 0.13 ENSDART00000139664
styk1
serine/threonine/tyrosine kinase 1
chr15_+_12429206 0.13 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr25_-_35145920 0.13 ENSDART00000157137
si:dkey-261m9.19
si:dkey-261m9.19
chr2_+_30721070 0.13 ENSDART00000099052
si:dkey-94e7.2
si:dkey-94e7.2
chr24_+_26006730 0.13 ENSDART00000140384
ENSDART00000139184
ccl20b
chemokine (C-C motif) ligand 20b
chr9_+_50001746 0.13 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr25_-_35106751 0.13 ENSDART00000180682
ENSDART00000073457
zgc:194989
zgc:194989
chr16_+_35594670 0.13 ENSDART00000163275
si:ch211-1i11.3
si:ch211-1i11.3
chr19_+_10603405 0.13 ENSDART00000151135
si:dkey-211g8.8
si:dkey-211g8.8
chr11_-_6048490 0.13 ENSDART00000066164
plvapb
plasmalemma vesicle associated protein b
chr8_+_48491387 0.12 ENSDART00000086053
PRDM16
si:ch211-263k4.2
chr19_+_4051695 0.12 ENSDART00000166368
btr24
bloodthirsty-related gene family, member 24
chr16_-_27566552 0.12 ENSDART00000142102
zgc:153215
zgc:153215
chr13_-_17723417 0.12 ENSDART00000183834
vdac2
voltage-dependent anion channel 2

Network of associatons between targets according to the STRING database.

First level regulatory network of sox19b+sox3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.7 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.5 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.4 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 0.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0043282 pharyngeal muscle development(GO:0043282)
0.0 0.2 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081) myeloid leukocyte cytokine production(GO:0061082)
0.0 0.2 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.1 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.2 GO:0036445 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554) positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0034154 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0050748 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0090190 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.1 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.0 0.2 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 0.1 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666)
0.0 0.0 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.6 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0034473 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.1 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.0 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.0 0.0 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.0 0.0 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 0.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.0 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.0 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.0 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.0 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.2 GO:0006942 regulation of striated muscle contraction(GO:0006942)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.0 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0034359 mature chylomicron(GO:0034359)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990715 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.4 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0004135 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.5 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.0 0.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1