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PRJNA207719: Tissue specific transcriptome profiling

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Results for sox1a+sox1b

Z-value: 0.30

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Transcription factors associated with sox1a+sox1b

Gene Symbol Gene ID Gene Info
sox1b
ENSDARG00000008131 SRY-box transcription factor 1b
sox1a
ENSDARG00000069866 SRY-box transcription factor 1a
sox1a
ENSDARG00000110682 SRY-box transcription factor 1a
sox1a
ENSDARG00000114571 SRY-box transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox1adr11_v1_chr9_+_21722733_21722733-0.197.6e-01Click!
sox1bdr11_v1_chr1_+_46194333_461943330.089.0e-01Click!

Activity profile of sox1a+sox1b motif

Sorted Z-values of sox1a+sox1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_18475032 0.28 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr20_-_40370736 0.21 ENSDART00000041229
fabp7b
fatty acid binding protein 7, brain, b
chr2_+_36620011 0.19 ENSDART00000177428
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr11_+_37612672 0.18 ENSDART00000157993
hp1bp3
heterochromatin protein 1, binding protein 3
chr23_+_31815423 0.18 ENSDART00000075730
ENSDART00000075726
myb
v-myb avian myeloblastosis viral oncogene homolog
chr14_+_36886950 0.17 ENSDART00000183719
si:ch211-132p1.3
si:ch211-132p1.3
chr14_-_9420911 0.16 ENSDART00000081158
sh3bgrl
SH3 domain binding glutamate-rich protein like
chr14_+_9421510 0.16 ENSDART00000123652
hmgn6
high mobility group nucleosome binding domain 6
chr19_-_41472228 0.15 ENSDART00000113388
dlx5a
distal-less homeobox 5a
chr15_-_951118 0.13 ENSDART00000171427
alox5b.1
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr3_-_33970190 0.13 ENSDART00000151238
ighj2-5
ighj2-5
chr1_+_51479128 0.12 ENSDART00000028018
meis1a
Meis homeobox 1 a
chr18_-_45761868 0.08 ENSDART00000025423
cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr19_+_20177887 0.08 ENSDART00000008595
tra2a
transformer 2 alpha homolog
chr11_-_45434959 0.08 ENSDART00000173106
ENSDART00000172767
ENSDART00000172933
ENSDART00000172986
rfc4
replication factor C (activator 1) 4
chr2_-_28420415 0.08 ENSDART00000183857
CABZ01056051.1

chr23_-_12158685 0.08 ENSDART00000135035
fam217b
family with sequence similarity 217, member B
chr2_-_53481912 0.08 ENSDART00000189610
hsd11b1lb
hydroxysteroid (11-beta) dehydrogenase 1-like b
chr2_+_48687528 0.07 ENSDART00000158312
si:dkey-53k12.1
si:dkey-53k12.1
chr7_-_6553460 0.07 ENSDART00000172903
si:ch1073-220m6.1
si:ch1073-220m6.1
chr20_+_37300699 0.07 ENSDART00000067053
vta1
vesicle (multivesicular body) trafficking 1
chr11_+_37612214 0.07 ENSDART00000172899
ENSDART00000077496
hp1bp3
heterochromatin protein 1, binding protein 3
chr16_-_44878245 0.07 ENSDART00000154391
ENSDART00000154925
ENSDART00000154697
arhgap33
Rho GTPase activating protein 33
chr3_+_4213864 0.06 ENSDART00000059613
si:dkeyp-52c3.5
si:dkeyp-52c3.5
chr20_+_37300296 0.06 ENSDART00000180789
vta1
vesicle (multivesicular body) trafficking 1
chr24_-_9291857 0.06 ENSDART00000149875
tgif1
TGFB-induced factor homeobox 1
chr5_+_30520249 0.06 ENSDART00000013431
hmbsa
hydroxymethylbilane synthase a
chr24_+_21092156 0.05 ENSDART00000028542
ccdc191
coiled-coil domain containing 191
chr1_+_50639416 0.05 ENSDART00000141977
herc3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr23_-_6982966 0.05 ENSDART00000033774
ENSDART00000169965
edem2
ER degradation enhancer, mannosidase alpha-like 2
chr20_+_27093042 0.04 ENSDART00000024595
ubr7
ubiquitin protein ligase E3 component n-recognin 7
chr12_-_4598237 0.04 ENSDART00000152489
irf3
interferon regulatory factor 3
chr19_+_23301050 0.04 ENSDART00000193713
si:dkey-79i2.4
si:dkey-79i2.4
chr1_+_25732715 0.04 ENSDART00000140172
npy2r
neuropeptide Y receptor Y2
chr19_+_18758014 0.04 ENSDART00000158935
clic1
chloride intracellular channel 1
chr7_-_71331690 0.03 ENSDART00000149682
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr20_-_23852174 0.03 ENSDART00000122414
si:dkey-15j16.6
si:dkey-15j16.6
chr1_-_9134045 0.03 ENSDART00000142132
palb2
partner and localizer of BRCA2
chr7_-_71331499 0.03 ENSDART00000081245
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr6_-_37513133 0.03 ENSDART00000147826
jade3
jade family PHD finger 3
chr8_+_49096486 0.02 ENSDART00000192998
zgc:56525
zgc:56525
chr2_+_31308587 0.02 ENSDART00000027090
clul1
clusterin-like 1 (retinal)
chr2_-_31833347 0.02 ENSDART00000109460
nol7
nucleolar protein 7
chr4_-_9664995 0.02 ENSDART00000180105
ENSDART00000029084
dmtf1
cyclin D binding myb-like transcription factor 1
chr1_+_59328030 0.02 ENSDART00000172464
CABZ01052576.1

chr16_-_21047483 0.02 ENSDART00000136235
cbx3b
chromobox homolog 3b
chr5_+_51833305 0.01 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr11_+_16216909 0.01 ENSDART00000081035
ENSDART00000147190
slc25a26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr7_+_1383027 0.01 ENSDART00000143762
khnyn
KH and NYN domain containing
chr25_-_27633115 0.01 ENSDART00000131539
hyal6
hyaluronoglucosaminidase 6
chr25_+_418932 0.01 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr5_+_51833132 0.01 ENSDART00000167491
papd4
PAP associated domain containing 4
chr9_+_2333927 0.01 ENSDART00000123340
atp5mc3a
ATP synthase membrane subunit c locus 3a
chr19_+_15440841 0.00 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr15_+_24005289 0.00 ENSDART00000088648
myo18ab
myosin XVIIIAb
chr6_-_22146258 0.00 ENSDART00000181700
gga1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr19_+_11978209 0.00 ENSDART00000111568
polr2k
polymerase (RNA) II (DNA directed) polypeptide K

Network of associatons between targets according to the STRING database.

First level regulatory network of sox1a+sox1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.1 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)