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PRJNA207719: Tissue specific transcriptome profiling

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Results for sox6

Z-value: 0.68

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Transcription factors associated with sox6

Gene Symbol Gene ID Gene Info
sox6
ENSDARG00000015536 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox6dr11_v1_chr7_+_27251376_27251475-0.128.5e-01Click!

Activity profile of sox6 motif

Sorted Z-values of sox6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_48340133 0.62 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr10_+_15608326 0.51 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr1_-_55810730 0.41 ENSDART00000100551
zgc:136908
zgc:136908
chr5_+_35458190 0.38 ENSDART00000051313
fbp1b
fructose-1,6-bisphosphatase 1b
chr24_-_40668208 0.35 ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr15_+_28368823 0.34 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr16_+_25245857 0.34 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr20_-_40754794 0.31 ENSDART00000187251
cx32.3
connexin 32.3
chr22_-_24967348 0.31 ENSDART00000153490
ENSDART00000084871
fam20cl
family with sequence similarity 20, member C like
chr13_-_20540790 0.31 ENSDART00000131467
si:ch1073-126c3.2
si:ch1073-126c3.2
chr7_+_39444843 0.30 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
tnnt3b
troponin T type 3b (skeletal, fast)
chr16_+_47308856 0.26 ENSDART00000170103
col28a1b
collagen, type XXVIII, alpha 1b
chr20_+_40237441 0.25 ENSDART00000168928
si:ch211-199i15.5
si:ch211-199i15.5
chr2_+_16780643 0.25 ENSDART00000125647
ENSDART00000108611
ENSDART00000181245
ENSDART00000163194
tfa
transferrin-a
chr24_-_29868151 0.25 ENSDART00000184802
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr8_+_17069577 0.24 ENSDART00000131847
si:dkey-190g11.3
si:dkey-190g11.3
chr12_-_22524388 0.23 ENSDART00000020942
shbg
sex hormone-binding globulin
chr5_+_10046643 0.23 ENSDART00000137543
ENSDART00000186917
gstt2
glutathione S-transferase theta 2
chr9_-_23891102 0.23 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18
chr5_-_46505691 0.23 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hapln1a
hyaluronan and proteoglycan link protein 1a
chr25_+_26798673 0.22 ENSDART00000157235
ca12
carbonic anhydrase XII
chr15_-_30853246 0.22 ENSDART00000112511
akap1b
A kinase (PRKA) anchor protein 1b
chr21_-_35853245 0.22 ENSDART00000172245
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr19_-_23249822 0.22 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr14_+_51056605 0.21 ENSDART00000159639
CABZ01078593.1

chr22_+_1028724 0.21 ENSDART00000149625
si:ch73-352p18.4
si:ch73-352p18.4
chr12_-_33354409 0.19 ENSDART00000178515
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr4_-_77432218 0.19 ENSDART00000158683
slco1d1
solute carrier organic anion transporter family, member 1D1
chr14_+_48812189 0.18 ENSDART00000161454
mmp17b
matrix metallopeptidase 17b
chr13_+_33368503 0.18 ENSDART00000139650
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr3_+_29641181 0.18 ENSDART00000151517
eif3d
eukaryotic translation initiation factor 3, subunit D
chr5_+_35458346 0.16 ENSDART00000141239
erlin2
ER lipid raft associated 2
chr17_-_2578026 0.15 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr20_-_33961697 0.15 ENSDART00000061765
selp
selectin P
chr17_-_2573021 0.15 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr8_+_14158021 0.14 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr7_-_17570923 0.14 ENSDART00000188476
ENSDART00000080624
nitr5
novel immune-type receptor 5
chr1_-_354115 0.13 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr2_-_24269911 0.13 ENSDART00000099532
myh7
myosin heavy chain 7
chr10_-_22831611 0.13 ENSDART00000160115
per1a
period circadian clock 1a
chr1_-_17735861 0.13 ENSDART00000018238
pdlim3a
PDZ and LIM domain 3a
chr16_-_21799407 0.13 ENSDART00000123717
FP015862.4

chr23_-_25798099 0.13 ENSDART00000041833
fitm2
fat storage-inducing transmembrane protein 2
chr15_-_35410860 0.12 ENSDART00000191267
mecom
MDS1 and EVI1 complex locus
chr19_-_10771558 0.12 ENSDART00000085165
slc9a3.2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 2
chr13_-_7567707 0.12 ENSDART00000190296
ENSDART00000180348
pitx3
paired-like homeodomain 3
chr25_+_13620555 0.12 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr14_-_41478265 0.12 ENSDART00000149886
ENSDART00000016002
tspan7
tetraspanin 7
chr5_+_55221593 0.11 ENSDART00000073638
tmc2a
transmembrane channel-like 2a
chr25_+_35502552 0.11 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr5_-_33606729 0.11 ENSDART00000137073
si:dkey-34e4.1
si:dkey-34e4.1
chr20_+_37295006 0.11 ENSDART00000153137
cx23
connexin 23
chr2_-_24270062 0.11 ENSDART00000192445
myh7
myosin heavy chain 7
chr11_-_9808356 0.11 ENSDART00000167465
nlgn1
neuroligin 1
chr21_-_41870029 0.11 ENSDART00000182035
endou2
endonuclease, polyU-specific 2
chr3_-_16250527 0.10 ENSDART00000146699
ENSDART00000141181
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr24_-_19719240 0.10 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr7_+_38255418 0.10 ENSDART00000052354
si:dkey-78a14.4
si:dkey-78a14.4
chr15_-_18067220 0.10 ENSDART00000113142
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr6_-_52675630 0.10 ENSDART00000083830
sdc4
syndecan 4
chr3_+_49074008 0.10 ENSDART00000168864
zgc:112146
zgc:112146
chr22_-_10440688 0.10 ENSDART00000111962
nol8
nucleolar protein 8
chr23_+_3538463 0.10 ENSDART00000172758
si:dkey-9l20.3
si:dkey-9l20.3
chr22_-_37565348 0.10 ENSDART00000149482
ENSDART00000104478
fxr1
fragile X mental retardation, autosomal homolog 1
chr5_+_7989210 0.10 ENSDART00000168071
gdnfb
glial cell derived neurotrophic factor b
chr23_+_27068225 0.09 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr11_+_31324335 0.09 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr17_-_2590222 0.09 ENSDART00000185711
CR759892.1

chr8_+_42941555 0.09 ENSDART00000183206
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr3_+_3099492 0.09 ENSDART00000154156
si:dkey-30g5.1
si:dkey-30g5.1
chr19_+_24575077 0.09 ENSDART00000167469
si:dkeyp-92c9.4
si:dkeyp-92c9.4
chr20_-_13722514 0.09 ENSDART00000152458
si:ch211-122h15.4
si:ch211-122h15.4
chr18_+_21122818 0.09 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr4_+_18804317 0.09 ENSDART00000101043
slc26a3.2
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr10_-_26163989 0.09 ENSDART00000136472
trim3b
tripartite motif containing 3b
chr7_+_48761875 0.08 ENSDART00000003690
acana
aggrecan a
chr1_-_33645967 0.08 ENSDART00000192758
cldng
claudin g
chr14_-_34771371 0.08 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
ablim3
actin binding LIM protein family, member 3
chr5_-_66160415 0.08 ENSDART00000073895
mboat4
membrane bound O-acyltransferase domain containing 4
chr9_-_22272181 0.08 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr3_-_21402279 0.08 ENSDART00000164513
CT573446.1

chr22_+_3045495 0.08 ENSDART00000164061
LO017843.1

chr2_+_23731194 0.08 ENSDART00000155747
slc22a13a
solute carrier family 22 member 13a
chr14_-_33978117 0.08 ENSDART00000128515
foxa
forkhead box A sequence
chr12_+_19320657 0.08 ENSDART00000100075
ENSDART00000066389
tmem184ba
transmembrane protein 184ba
chr9_+_50001746 0.08 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr5_+_19097194 0.08 ENSDART00000131918
unc13ba
unc-13 homolog Ba (C. elegans)
chr7_+_48761646 0.07 ENSDART00000017467
acana
aggrecan a
chr4_+_65607540 0.07 ENSDART00000192218
si:dkey-205i10.2
si:dkey-205i10.2
chr10_+_39200213 0.07 ENSDART00000153727
ei24
etoposide induced 2.4
chr8_+_17869225 0.07 ENSDART00000080079
slc44a5b
solute carrier family 44, member 5b
chr7_+_22688781 0.07 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr1_+_17376922 0.07 ENSDART00000145068
fat1a
FAT atypical cadherin 1a
chr11_+_10541258 0.07 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr5_-_20195350 0.06 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr14_+_52565660 0.06 ENSDART00000188151
rpl26
ribosomal protein L26
chr16_-_42186093 0.06 ENSDART00000076030
fbl
fibrillarin
chr23_+_5499307 0.06 ENSDART00000170361
tead3a
TEA domain family member 3 a
chr22_-_12746539 0.06 ENSDART00000175374
plcd4a
phospholipase C, delta 4a
chr16_+_53387085 0.05 ENSDART00000154223
ENSDART00000101404
kif13a
kinesin family member 13A
chr5_-_31875645 0.05 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr25_+_28567381 0.05 ENSDART00000126552
SLC15A5
si:ch211-190o6.3
chr25_+_13271458 0.05 ENSDART00000188307
AL772241.1

chr10_+_16069987 0.05 ENSDART00000043936
megf10
multiple EGF-like-domains 10
chr2_-_5942115 0.05 ENSDART00000154489
tmem125b
transmembrane protein 125b
chr4_-_76154252 0.05 ENSDART00000161269
BX957252.1

chr17_-_45386546 0.05 ENSDART00000182647
tmem206
transmembrane protein 206
chr23_-_21471022 0.05 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr9_-_14084044 0.05 ENSDART00000141571
fer1l6
fer-1-like family member 6
chr19_-_27339844 0.05 ENSDART00000052358
ENSDART00000148238
ENSDART00000147661
ENSDART00000137346
znrd1
zinc ribbon domain containing 1
chr1_-_50791280 0.05 ENSDART00000181224
CABZ01031870.1

chr6_-_41138854 0.05 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr4_+_29702703 0.05 ENSDART00000167771
si:ch211-214c20.1
si:ch211-214c20.1
chr21_+_36396864 0.04 ENSDART00000137309
gemin5
gem (nuclear organelle) associated protein 5
chr11_-_7147540 0.04 ENSDART00000143942
bmp7a
bone morphogenetic protein 7a
chr19_-_27588842 0.04 ENSDART00000121643
si:dkeyp-46h3.2
si:dkeyp-46h3.2
chr21_+_34119759 0.04 ENSDART00000024750
ENSDART00000128242
hmgb3b
high mobility group box 3b
chr25_-_16076257 0.04 ENSDART00000140780
ovch2
ovochymase 2
chr23_-_21453614 0.04 ENSDART00000079274
her4.1
hairy-related 4, tandem duplicate 1
chr12_+_42400277 0.04 ENSDART00000166590
si:ch211-221j21.3
si:ch211-221j21.3
chr2_-_10896745 0.04 ENSDART00000114609
cdcp2
CUB domain containing protein 2
chr23_-_21463788 0.04 ENSDART00000079265
her4.4
hairy-related 4, tandem duplicate 4
chr13_-_11699530 0.04 ENSDART00000192161
slc39a8
solute carrier family 39 (zinc transporter), member 8
chr7_+_65876335 0.04 ENSDART00000150143
tead1b
TEA domain family member 1b
chr1_-_31534089 0.04 ENSDART00000007770
lbx1b
ladybird homeobox 1b
chr16_+_27349585 0.04 ENSDART00000142573
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr15_-_20779624 0.04 ENSDART00000181936
tpst1
tyrosylprotein sulfotransferase 1
chr3_+_29640996 0.04 ENSDART00000011052
eif3d
eukaryotic translation initiation factor 3, subunit D
chr17_-_20228610 0.04 ENSDART00000125758
ebf3b
early B cell factor 3b
chr11_-_3381343 0.04 ENSDART00000002545
mcrs1
microspherule protein 1
chr17_-_45386823 0.04 ENSDART00000156002
tmem206
transmembrane protein 206
chr13_+_42309688 0.04 ENSDART00000158367
ide
insulin-degrading enzyme
chr12_+_38697541 0.03 ENSDART00000188648
dnai2b
dynein, axonemal, intermediate chain 2b
chr16_-_22006996 0.03 ENSDART00000116114
si:dkey-71b5.7
si:dkey-71b5.7
chr7_-_6459481 0.03 ENSDART00000173158
zgc:112234
zgc:112234
chr4_-_63848305 0.03 ENSDART00000097308
BX901974.1

chr23_-_7826849 0.03 ENSDART00000157612
myt1b
myelin transcription factor 1b
chr21_-_2310064 0.03 ENSDART00000169520
si:ch211-241b2.1
si:ch211-241b2.1
chr15_-_5563551 0.03 ENSDART00000099520
atg16l2
ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr10_+_44042033 0.03 ENSDART00000190006
ENSDART00000046172
cryba4
crystallin, beta A4
chr2_+_26479676 0.03 ENSDART00000056795
ENSDART00000144837
hectd3
HECT domain containing 3
chr10_+_5744941 0.03 ENSDART00000159769
ENSDART00000184734
pam
peptidylglycine alpha-amidating monooxygenase
chr8_-_49499457 0.03 ENSDART00000098326
opn7d
opsin 7, group member d
chr24_+_18714212 0.03 ENSDART00000171181
cspp1a
centrosome and spindle pole associated protein 1a
chr23_-_5685023 0.03 ENSDART00000148680
ENSDART00000149365
tnnt2a
troponin T type 2a (cardiac)
chr15_+_29727799 0.03 ENSDART00000182006
zgc:153372
zgc:153372
chr7_+_25103965 0.03 ENSDART00000192561
ENSDART00000173721
si:dkey-23i12.9
si:dkey-23i12.9
chr25_-_22889519 0.02 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr23_+_21459263 0.02 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr25_+_25737386 0.02 ENSDART00000108476
lrrc61
leucine rich repeat containing 61
chr20_+_35445462 0.02 ENSDART00000124497
tdrd6
tudor domain containing 6
chr22_-_18546241 0.02 ENSDART00000105404
ENSDART00000105405
cirbpb
cold inducible RNA binding protein b
chr15_-_41503392 0.02 ENSDART00000169351
si:dkey-230i18.2
si:dkey-230i18.2
chr3_+_3545825 0.02 ENSDART00000109060
CR589947.1

chr6_+_54358529 0.02 ENSDART00000153704
anks1ab
ankyrin repeat and sterile alpha motif domain containing 1Ab
chr23_+_30827959 0.02 ENSDART00000033429
npbwr2a
neuropeptides B/W receptor 2a
chr19_+_19762183 0.02 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr7_-_24520866 0.02 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr2_+_47623202 0.02 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr7_+_20019125 0.02 ENSDART00000186391
bcl6b
B-cell CLL/lymphoma 6, member B
chr15_+_19458982 0.02 ENSDART00000132665
zgc:77784
zgc:77784
chr14_-_1990290 0.02 ENSDART00000183382
pcdh2g5
protocadherin 2 gamma 5
chr21_+_11105007 0.01 ENSDART00000128859
ENSDART00000193105
prlra
prolactin receptor a
chr5_+_40835601 0.01 ENSDART00000147767
si:dkey-3h3.3
si:dkey-3h3.3
chr19_-_18152407 0.01 ENSDART00000193264
ENSDART00000016135
nfe2l3
nuclear factor, erythroid 2-like 3
chr1_-_47431453 0.01 ENSDART00000101104
gja5b
gap junction protein, alpha 5b
chr13_+_46941930 0.01 ENSDART00000056962
fbxo5
F-box protein 5
chr10_+_21722892 0.01 ENSDART00000162855
pcdh1g13
protocadherin 1 gamma 13
chr7_-_24373662 0.01 ENSDART00000173865
PTGR1 (1 of many)
si:dkey-11k2.7
chr3_+_3992590 0.01 ENSDART00000180211
ENSDART00000054840
BX005421.2

chr7_-_32895668 0.01 ENSDART00000141828
ano5b
anoctamin 5b
chr6_+_58280936 0.01 ENSDART00000155244
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr7_-_73852594 0.01 ENSDART00000183194
zgc:165555
zgc:165555
chr25_-_3503164 0.00 ENSDART00000191477
ENSDART00000186345
ENSDART00000180199
PRKAR2B
si:ch211-272n13.7
chr5_-_38384289 0.00 ENSDART00000135260
mink1
misshapen-like kinase 1
chr12_+_5081759 0.00 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr17_+_7534365 0.00 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr3_-_26524934 0.00 ENSDART00000087118
xylt1
xylosyltransferase I
chr10_+_3428194 0.00 ENSDART00000081599
ptpn11a
protein tyrosine phosphatase, non-receptor type 11, a
chr10_+_21677058 0.00 ENSDART00000171499
ENSDART00000157516
pcdh1gb2
protocadherin 1 gamma b 2
chr17_+_26208630 0.00 ENSDART00000087084
grid1a
glutamate receptor, ionotropic, delta 1a
chr7_-_24995631 0.00 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr12_+_40810418 0.00 ENSDART00000183393
CDH18
cadherin 18
chr23_-_33944597 0.00 ENSDART00000133223
si:dkey-190g6.2
si:dkey-190g6.2
chr15_+_12429206 0.00 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a

Network of associatons between targets according to the STRING database.

First level regulatory network of sox6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.4 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.1 GO:0090189 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.1 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.1 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.3 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.2 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.1 GO:0006833 water transport(GO:0006833)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters