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PRJNA207719: Tissue specific transcriptome profiling

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Results for sp3b

Z-value: 1.08

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Transcription factors associated with sp3b

Gene Symbol Gene ID Gene Info
sp3b
ENSDARG00000007812 Sp3b transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp3bdr11_v1_chr6_-_10740365_10740365-0.573.1e-01Click!

Activity profile of sp3b motif

Sorted Z-values of sp3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_77557279 1.51 ENSDART00000180113
AL935186.10

chr22_+_1006573 1.02 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr24_-_36593876 0.93 ENSDART00000160901
CABZ01055365.1

chr17_-_125091 0.80 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr13_+_41022502 0.77 ENSDART00000026808
dkk1a
dickkopf WNT signaling pathway inhibitor 1a
chr17_-_2584423 0.72 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr4_+_55758103 0.71 ENSDART00000185964
CT583728.23

chr7_-_16598212 0.69 ENSDART00000128488
e2f8
E2F transcription factor 8
chr12_+_46634736 0.68 ENSDART00000008009
trim16
tripartite motif containing 16
chr23_-_45407631 0.68 ENSDART00000148484
ENSDART00000150186
zgc:101853
zgc:101853
chr3_-_40276057 0.68 ENSDART00000132225
ENSDART00000074737
shmt1
serine hydroxymethyltransferase 1 (soluble)
chr3_+_1211242 0.67 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr20_-_40370736 0.59 ENSDART00000041229
fabp7b
fatty acid binding protein 7, brain, b
chr1_+_144284 0.59 ENSDART00000064061
prozb
protein Z, vitamin K-dependent plasma glycoprotein b
chr6_+_102506 0.59 ENSDART00000172678
ldlrb
low density lipoprotein receptor b
chr4_-_68569527 0.56 ENSDART00000192091
BX548011.5

chr24_+_38671054 0.53 ENSDART00000154214
si:ch73-70c5.1
si:ch73-70c5.1
chr8_-_31107537 0.51 ENSDART00000098925
vgll4l
vestigial like 4 like
chr5_-_1047504 0.49 ENSDART00000159346
mbd2
methyl-CpG binding domain protein 2
chr4_-_77551860 0.47 ENSDART00000188176
AL935186.6

chr3_-_32541033 0.47 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr3_+_29469283 0.46 ENSDART00000103592
fam83fa
family with sequence similarity 83, member Fa
chr22_-_10752471 0.45 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr19_+_636886 0.45 ENSDART00000149192
tert
telomerase reverse transcriptase
chr20_-_21672970 0.43 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr19_+_48117995 0.43 ENSDART00000170865
nme2b.1
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr4_-_77563411 0.41 ENSDART00000186841
AL935186.8

chr3_-_61162750 0.41 ENSDART00000055064
pvalb8
parvalbumin 8
chr8_+_6576940 0.40 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr6_+_3334710 0.40 ENSDART00000132848
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr5_+_66132394 0.40 ENSDART00000073892
zgc:114041
zgc:114041
chr13_-_31647323 0.40 ENSDART00000135381
six4a
SIX homeobox 4a
chr18_-_6803424 0.39 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr1_+_59538755 0.39 ENSDART00000166354
sp6
Sp6 transcription factor
chr4_+_5537101 0.38 ENSDART00000008692
si:dkey-14d8.7
si:dkey-14d8.7
chr19_+_156757 0.38 ENSDART00000167717
carmil1
capping protein regulator and myosin 1 linker 1
chr23_-_13875252 0.38 ENSDART00000104834
ENSDART00000193807
g6pd
glucose-6-phosphate dehydrogenase
chr16_-_29387215 0.38 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr16_+_29650698 0.37 ENSDART00000137153
tmod4
tropomodulin 4 (muscle)
chr3_+_32526799 0.37 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr3_+_5575313 0.35 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
si:ch211-106h11.3
chr16_+_46294337 0.35 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr8_+_51958968 0.35 ENSDART00000139509
ENSDART00000186544
gna14a
guanine nucleotide binding protein (G protein), alpha 14a
chr17_-_114121 0.35 ENSDART00000172408
ENSDART00000157784
arhgap11a
Rho GTPase activating protein 11A
chr18_-_26715655 0.34 ENSDART00000181497
malt3
MALT paracaspase 3
chr1_-_58562129 0.34 ENSDART00000159070
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr20_+_26556174 0.33 ENSDART00000138492
irf4b
interferon regulatory factor 4b
chr20_+_26556372 0.33 ENSDART00000187179
ENSDART00000157291
irf4b
interferon regulatory factor 4b
chr21_+_10577527 0.32 ENSDART00000165070
ENSDART00000127963
ccbe1
collagen and calcium binding EGF domains 1
chr9_-_8314028 0.32 ENSDART00000102739
si:ch211-145c1.1
si:ch211-145c1.1
chr22_+_26443235 0.32 ENSDART00000044085
zgc:92480
zgc:92480
chr20_-_182841 0.32 ENSDART00000064546
si:ch211-241j12.3
si:ch211-241j12.3
chr6_-_442163 0.32 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
grap2b
GRB2-related adaptor protein 2b
chr22_+_344763 0.32 ENSDART00000181934
CU914780.1

chr11_-_40504170 0.31 ENSDART00000165394
si:dkeyp-61b2.1
si:dkeyp-61b2.1
chr23_-_31645760 0.31 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr25_+_16356083 0.31 ENSDART00000125925
ENSDART00000125444
tead1a
TEA domain family member 1a
chr12_-_45349849 0.31 ENSDART00000183036
CABZ01068367.1
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr22_-_17729778 0.30 ENSDART00000192132
si:ch73-63e15.2
si:ch73-63e15.2
chr3_-_50139860 0.30 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr21_-_26490186 0.30 ENSDART00000009889
zgc:110540
zgc:110540
chr22_-_188102 0.30 ENSDART00000125391
ENSDART00000170463
CABZ01052268.1

chr15_+_11644866 0.29 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr16_+_26732086 0.29 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr3_+_32526263 0.29 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr24_+_37449893 0.29 ENSDART00000164405
nlrc3
NLR family, CARD domain containing 3
chr15_+_19838458 0.29 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr3_+_26813058 0.29 ENSDART00000055537
socs1a
suppressor of cytokine signaling 1a
chr21_-_32436679 0.29 ENSDART00000076974
gfpt2
glutamine-fructose-6-phosphate transaminase 2
chr17_+_12075805 0.29 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr22_-_34979139 0.29 ENSDART00000116455
ENSDART00000133537
arhgap19
Rho GTPase activating protein 19
chr7_-_64971839 0.28 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr1_+_51475094 0.28 ENSDART00000146352
meis1a
Meis homeobox 1 a
chr20_-_147574 0.28 ENSDART00000104762
ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr1_-_58561963 0.28 ENSDART00000165040
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr8_-_410728 0.27 ENSDART00000151255
trim36
tripartite motif containing 36
chr7_-_12968689 0.27 ENSDART00000173115
ENSDART00000013690
rplp2l
ribosomal protein, large P2, like
chr18_-_41161828 0.27 ENSDART00000114993
CABZ01005876.1

chr21_-_5056812 0.27 ENSDART00000139713
ENSDART00000140859
zgc:77838
zgc:77838
chr6_+_3334392 0.27 ENSDART00000133707
ENSDART00000130879
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr10_-_22150419 0.26 ENSDART00000006173
cldn7b
claudin 7b
chr16_-_6849754 0.26 ENSDART00000149206
ENSDART00000149778
mbpb
myelin basic protein b
chr12_+_10443785 0.26 ENSDART00000029133
snu13b
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr18_-_26715156 0.26 ENSDART00000142043
malt3
MALT paracaspase 3
chr6_+_27338512 0.26 ENSDART00000155004
klhl30
kelch-like family member 30
chr16_-_5143124 0.25 ENSDART00000131876
ENSDART00000060630
ttk
ttk protein kinase
chr11_+_329687 0.25 ENSDART00000172882
cyp27b1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr19_+_48111285 0.25 ENSDART00000169420
nme2b.2
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr2_-_47620806 0.24 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr25_-_34284144 0.24 ENSDART00000188109
gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr13_-_33671694 0.24 ENSDART00000143945
ENSDART00000100504
zgc:163030
zgc:163030
chr6_+_584632 0.24 ENSDART00000151150
zgc:92360
zgc:92360
chr2_+_11028923 0.24 ENSDART00000076725
acot11a
acyl-CoA thioesterase 11a
chr6_+_41503854 0.24 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr4_+_77981553 0.23 ENSDART00000174108
ENSDART00000122459
terfa
telomeric repeat binding factor a
chr2_+_44512324 0.23 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr10_-_33621739 0.23 ENSDART00000142655
ENSDART00000128049
hunk
hormonally up-regulated Neu-associated kinase
chr19_+_4912817 0.23 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr20_+_37794633 0.23 ENSDART00000022060
atf3
activating transcription factor 3
chr5_+_6617401 0.23 ENSDART00000060532
zgc:110796
zgc:110796
chr22_+_396840 0.23 ENSDART00000163198
capzb
capping protein (actin filament) muscle Z-line, beta
chr7_+_49664174 0.22 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr7_+_44802353 0.22 ENSDART00000066380
ca7
carbonic anhydrase VII
chr13_+_45582391 0.22 ENSDART00000058093
ldlrap1b
low density lipoprotein receptor adaptor protein 1b
chr6_-_141564 0.22 ENSDART00000151245
ENSDART00000063876
s1pr5b
sphingosine-1-phosphate receptor 5b
chr21_-_45086170 0.22 ENSDART00000188963
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr3_+_49043917 0.22 ENSDART00000158212
zgc:92161
zgc:92161
chr19_+_48117388 0.22 ENSDART00000160549
nme2b.1
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr24_+_17005647 0.22 ENSDART00000149149
zfx
zinc finger protein, X-linked
chr3_-_18030938 0.21 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr7_+_13988075 0.21 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr18_-_3166726 0.21 ENSDART00000165002
aqp11
aquaporin 11
chr22_-_5441893 0.21 ENSDART00000161421
zgc:194627
zgc:194627
chr1_-_54107321 0.21 ENSDART00000148382
ENSDART00000150357
rfx1b
regulatory factor X, 1b (influences HLA class II expression)
chr16_+_32152612 0.21 ENSDART00000008880
gprc6a
G protein-coupled receptor, class C, group 6, member A
chr25_+_22319940 0.21 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr20_-_54381034 0.21 ENSDART00000136779
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr17_-_4395373 0.20 ENSDART00000015923
klhl10a
kelch-like family member 10a
chr22_+_10090673 0.20 ENSDART00000186680
si:dkey-102c8.3
si:dkey-102c8.3
chr19_+_4892281 0.20 ENSDART00000150969
cdk12
cyclin-dependent kinase 12
chr2_+_11029138 0.20 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acot11a
acyl-CoA thioesterase 11a
chr25_+_35133404 0.20 ENSDART00000188505
hist1h2a2
histone cluster 1 H2A family member 2
chr18_-_15467446 0.19 ENSDART00000187847
endouc
endonuclease, polyU-specific C
chr24_+_35564668 0.19 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr2_+_55365727 0.19 ENSDART00000162943
FP245456.1

chr19_+_48251273 0.19 ENSDART00000157424
CU693379.1

chr5_+_38200807 0.19 ENSDART00000100769
hsd20b2
hydroxysteroid (20-beta) dehydrogenase 2
chr1_+_44127292 0.19 ENSDART00000160542
cabp2a
calcium binding protein 2a
chr7_+_48870496 0.19 ENSDART00000009642
igf2a
insulin-like growth factor 2a
chr13_-_17860307 0.19 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr13_-_44808783 0.19 ENSDART00000099984
glo1
glyoxalase 1
chr13_+_2830574 0.19 ENSDART00000138143
si:ch211-233m11.1
si:ch211-233m11.1
chr16_-_20707742 0.19 ENSDART00000103630
creb5b
cAMP responsive element binding protein 5b
chr7_-_6364168 0.19 ENSDART00000173332
zgc:112234
zgc:112234
chr20_-_22378401 0.18 ENSDART00000011135
ENSDART00000110967
kita
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr16_-_26731928 0.18 ENSDART00000135860
rnf41l
ring finger protein 41, like
chr25_+_4750972 0.18 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr18_-_7810214 0.18 ENSDART00000139505
ENSDART00000139188
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr2_-_58075414 0.18 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr2_-_23479714 0.18 ENSDART00000167291
si:ch211-14p21.3
si:ch211-14p21.3
chr22_+_336256 0.18 ENSDART00000019155
btg2
B-cell translocation gene 2
chr20_+_15982482 0.18 ENSDART00000020999
angptl1a
angiopoietin-like 1a
chr3_+_22273123 0.17 ENSDART00000044157
scn4ab
sodium channel, voltage-gated, type IV, alpha, b
chr14_-_31694274 0.17 ENSDART00000173353
map7d3
MAP7 domain containing 3
chr10_+_22034477 0.17 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
npm1a
nucleophosmin 1a
chr1_-_59216197 0.17 ENSDART00000062426
lpar2b
lysophosphatidic acid receptor 2b
chr4_-_2380173 0.17 ENSDART00000177727
nap1l1
nucleosome assembly protein 1-like 1
chr25_+_21098990 0.17 ENSDART00000017488
rad52
RAD52 homolog, DNA repair protein
chr5_-_22969424 0.17 ENSDART00000143869
ENSDART00000172549
si:dkey-237j10.2
si:dkey-237j10.2
chr18_-_8889382 0.17 ENSDART00000058647
ENSDART00000184944
si:dkey-95h12.1
si:dkey-95h12.1
chr25_+_1732838 0.17 ENSDART00000159555
ENSDART00000168161
FBLN1
fibulin 1
chr21_-_45891262 0.16 ENSDART00000169816
galnt10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr15_-_43164591 0.16 ENSDART00000171305
ap1s3a
adaptor-related protein complex 1, sigma 3 subunit, a
chr9_+_21146862 0.16 ENSDART00000136365
hao2
hydroxyacid oxidase 2 (long chain)
chr12_-_47774807 0.16 ENSDART00000193831
LO017725.1

chr25_-_35143360 0.16 ENSDART00000188033
zgc:165555
zgc:165555
chr6_+_38879961 0.16 ENSDART00000184798
bin2b
bridging integrator 2b
chr6_+_42338309 0.16 ENSDART00000015277
gpx1b
glutathione peroxidase 1b
chr7_-_16596938 0.16 ENSDART00000134548
e2f8
E2F transcription factor 8
chr22_-_24900121 0.16 ENSDART00000147643
si:dkey-4c23.3
si:dkey-4c23.3
chr1_-_57501299 0.16 ENSDART00000080600
zgc:171470
zgc:171470
chr19_-_5058908 0.16 ENSDART00000130062
chd4a
chromodomain helicase DNA binding protein 4a
chr17_+_53435279 0.15 ENSDART00000126630
cx52.9
connexin 52.9
chr3_+_12554801 0.15 ENSDART00000167177
ccnf
cyclin F
chr10_+_8885769 0.15 ENSDART00000139466
itga2.2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr15_-_2726662 0.15 ENSDART00000108856
si:ch211-235m3.5
si:ch211-235m3.5
chr8_+_10305400 0.15 ENSDART00000172400
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr14_-_2602445 0.15 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr15_+_29024895 0.15 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr23_+_44049509 0.15 ENSDART00000102003
txk
TXK tyrosine kinase
chr18_-_50799510 0.15 ENSDART00000174373
taldo1
transaldolase 1
chr20_+_2731436 0.15 ENSDART00000058779
ENSDART00000129870
ENSDART00000132186
ENSDART00000152727
syncrip
synaptotagmin binding, cytoplasmic RNA interacting protein
chr4_-_4612116 0.15 ENSDART00000130601
CABZ01020840.1
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr20_+_46897504 0.15 ENSDART00000158124
si:ch73-21k16.1
si:ch73-21k16.1
chr25_+_21098675 0.15 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr23_+_44157682 0.15 ENSDART00000164474
ENSDART00000149928
si:ch73-106g13.1
si:ch73-106g13.1
chr6_-_10788065 0.15 ENSDART00000190968
wipf1b
WAS/WASL interacting protein family, member 1b
chr14_-_7207961 0.15 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr1_-_54100988 0.14 ENSDART00000192662
rfx1b
regulatory factor X, 1b (influences HLA class II expression)
chr9_+_13999620 0.14 ENSDART00000143229
cd28l
cd28-like molecule
chr24_-_21914276 0.14 ENSDART00000128687
c1qtnf9
C1q and TNF related 9
chr25_+_37443194 0.14 ENSDART00000163178
ENSDART00000190262
slc10a3
solute carrier family 10, member 3
chr3_+_46559639 0.14 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
raver1
ribonucleoprotein, PTB-binding 1
chr7_-_16597130 0.14 ENSDART00000144118
e2f8
E2F transcription factor 8
chr10_+_187760 0.14 ENSDART00000161007
ENSDART00000160651
ets2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr11_-_11878099 0.14 ENSDART00000188314
wipf2a
WAS/WASL interacting protein family, member 2a
chr6_+_52918537 0.14 ENSDART00000174229
or137-1
odorant receptor, family H, subfamily 137, member 1
chr23_+_19655301 0.14 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr25_+_36311333 0.14 ENSDART00000190174
hist1h2a2
histone cluster 1 H2A family member 2
chr4_+_3980247 0.14 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr10_+_10788811 0.14 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr7_-_33114884 0.14 ENSDART00000052385
tph1b
tryptophan hydroxylase 1b
chr5_-_22619879 0.13 ENSDART00000051623
zgc:113208
zgc:113208
chr8_+_29963024 0.13 ENSDART00000149372
ptch1
patched 1
chr7_+_55112922 0.13 ENSDART00000073549
snai3
snail family zinc finger 3
chr13_+_37022601 0.13 ENSDART00000131800
ENSDART00000041300
esr2b
estrogen receptor 2b
chr9_-_39968820 0.13 ENSDART00000100311
IKZF2
si:zfos-1425h8.1
chr20_-_54564018 0.13 ENSDART00000099832
zgc:153012
zgc:153012
chr6_-_10791880 0.13 ENSDART00000104884
wipf1b
WAS/WASL interacting protein family, member 1b
chr10_+_44924684 0.13 ENSDART00000181360
ENSDART00000170418
ENSDART00000170327
sec14l7
SEC14-like lipid binding 7

Network of associatons between targets according to the STRING database.

First level regulatory network of sp3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 0.7 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.1 0.4 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.4 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.6 GO:0071071 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 1.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.3 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.3 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.3 GO:1902102 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.5 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 0.9 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.3 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0060876 semicircular canal formation(GO:0060876)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.7 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0021885 forebrain cell migration(GO:0021885)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.8 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.2 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.1 GO:0090190 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.1 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.0 0.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:0097037 heme export(GO:0097037)
0.0 0.2 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) intermediate mesoderm development(GO:0048389) convergent extension involved in nephron morphogenesis(GO:0072045)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.1 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.2 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.0 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0060036 notochord cell vacuolation(GO:0060036)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.2 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 1.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.3 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling