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PRJNA207719: Tissue specific transcriptome profiling

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Results for stat3

Z-value: 0.68

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Transcription factors associated with stat3

Gene Symbol Gene ID Gene Info
stat3
ENSDARG00000022712 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat3dr11_v1_chr3_+_17030665_170307040.118.7e-01Click!

Activity profile of stat3 motif

Sorted Z-values of stat3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_45626136 0.63 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr23_-_10175898 0.46 ENSDART00000146185
krt5
keratin 5
chr13_-_37642890 0.43 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
si:dkey-188i13.9
chr4_+_7391400 0.42 ENSDART00000169111
ENSDART00000186395
tnni4a
troponin I4a
chr13_+_52061034 0.41 ENSDART00000170383
CABZ01089777.1

chr19_+_712127 0.40 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr13_-_37608441 0.40 ENSDART00000140230
zgc:123068
zgc:123068
chr11_-_17964525 0.37 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr17_-_10838434 0.36 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr5_-_42071505 0.31 ENSDART00000137224
ENSDART00000193721
cxcl11.7
cenpv
chemokine (C-X-C motif) ligand 11, duplicate 7
centromere protein V
chr21_-_27338639 0.29 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr14_+_7452302 0.28 ENSDART00000130388
gfra3
GDNF family receptor alpha 3
chr22_-_5323482 0.26 ENSDART00000145785
s1pr4
sphingosine-1-phosphate receptor 4
chr3_+_59899452 0.24 ENSDART00000064311
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr24_-_33291784 0.24 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr20_-_37813863 0.24 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr5_-_26466169 0.24 ENSDART00000144035
arvcfb
ARVCF, delta catenin family member b
chr21_+_43328685 0.23 ENSDART00000109620
ENSDART00000139668
sept8a
septin 8a
chr23_-_5783421 0.22 ENSDART00000131521
ENSDART00000019455
csrp1a
cysteine and glycine-rich protein 1a
chr19_+_10587307 0.22 ENSDART00000131225
si:dkey-211g8.4
si:dkey-211g8.4
chr9_-_23922778 0.22 ENSDART00000135769
col6a3
collagen, type VI, alpha 3
chr10_-_4375190 0.22 ENSDART00000016102
CABZ01073795.1

chr22_+_7480465 0.21 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr11_+_12720171 0.21 ENSDART00000135761
ENSDART00000122812
ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr9_-_23922011 0.20 ENSDART00000145734
col6a3
collagen, type VI, alpha 3
chr3_-_35541378 0.20 ENSDART00000183075
ENSDART00000022147
ndufab1b
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1b
chr1_-_9114936 0.20 ENSDART00000163624
ENSDART00000132910
si:ch211-14k19.8
vap
si:ch211-14k19.8
vascular associated protein
chr4_+_76735113 0.19 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr8_+_26329482 0.19 ENSDART00000048676
prkar2aa
protein kinase, cAMP-dependent, regulatory, type II, alpha A
chr16_-_38001040 0.19 ENSDART00000133861
ENSDART00000138711
ENSDART00000143846
ENSDART00000146564
si:ch211-198c19.3
si:ch211-198c19.3
chr8_-_17997845 0.18 ENSDART00000121660
acot11b
acyl-CoA thioesterase 11b
chr3_-_57425961 0.18 ENSDART00000033716
socs3a
suppressor of cytokine signaling 3a
chr5_-_42883761 0.18 ENSDART00000167374
BX323596.2

chr9_-_9282519 0.18 ENSDART00000146821
si:ch211-214p13.3
si:ch211-214p13.3
chr12_+_23875318 0.18 ENSDART00000152869
svila
supervillin a
chr19_+_43359075 0.18 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr12_+_22657925 0.17 ENSDART00000153048
si:dkey-219e21.4
si:dkey-219e21.4
chr20_-_39273987 0.17 ENSDART00000127173
clu
clusterin
chr11_+_11200550 0.16 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr23_+_45734011 0.16 ENSDART00000062415
CABZ01088025.1

chr17_-_45378473 0.16 ENSDART00000132969
znf106a
zinc finger protein 106a
chr24_-_27452488 0.16 ENSDART00000136433
ccl34b.8
chemokine (C-C motif) ligand 34b, duplicate 8
chr3_+_40289418 0.16 ENSDART00000017304
cpsf4
cleavage and polyadenylation specific factor 4
chr4_-_1818315 0.15 ENSDART00000067433
ube2nb
ubiquitin-conjugating enzyme E2Nb
chr23_-_5101847 0.15 ENSDART00000122240
etv7
ets variant 7
chr9_-_54304684 0.15 ENSDART00000109512
il13
interleukin 13
chr20_+_46572550 0.15 ENSDART00000139051
ENSDART00000161320
batf
basic leucine zipper transcription factor, ATF-like
chr22_-_834106 0.14 ENSDART00000105873
cry4
cryptochrome circadian clock 4
chr14_+_15257658 0.14 ENSDART00000161625
ENSDART00000193577
si:dkey-77g12.4
si:dkey-203a12.5
si:dkey-77g12.4
si:dkey-203a12.5
chr12_+_17042754 0.14 ENSDART00000066439
ch25h
cholesterol 25-hydroxylase
chr13_-_37631092 0.14 ENSDART00000108855
si:dkey-188i13.7
si:dkey-188i13.7
chr11_-_22303678 0.13 ENSDART00000159527
ENSDART00000159681
tfeb
transcription factor EB
chr7_+_65586624 0.13 ENSDART00000184344
mical2a
microtubule associated monooxygenase, calponin and LIM domain containing 2a
chr21_+_13150937 0.13 ENSDART00000102251
sptan1
spectrin alpha, non-erythrocytic 1
chr19_-_35052451 0.13 ENSDART00000152030
macf1a
microtubule-actin crosslinking factor 1a
chr1_-_10669436 0.13 ENSDART00000152421
si:dkey-31e10.5
si:dkey-31e10.5
chr23_+_5524247 0.13 ENSDART00000189679
ENSDART00000083622
tead3a
TEA domain family member 3 a
chr6_+_43015916 0.13 ENSDART00000064888
tcta
T cell leukemia translocation altered
chr7_-_22790630 0.13 ENSDART00000173496
si:ch211-15b10.6
si:ch211-15b10.6
chr5_-_23619911 0.13 ENSDART00000020004
mtmr2
myotubularin related protein 2
chr15_-_1485086 0.13 ENSDART00000191651
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr2_+_4402765 0.13 ENSDART00000159525
bambib
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr18_-_26797723 0.13 ENSDART00000008013
sec11a
SEC11 homolog A, signal peptidase complex subunit
chr1_+_5402476 0.13 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr4_-_4592287 0.12 ENSDART00000155287
rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr11_+_4026229 0.12 ENSDART00000041417
camk1b
calcium/calmodulin-dependent protein kinase Ib
chr19_+_7938121 0.12 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
si:dkey-266f7.5
chr7_+_38809241 0.12 ENSDART00000190979
harbi1
harbinger transposase derived 1
chr15_-_23475051 0.12 ENSDART00000152460
nlrx1
NLR family member X1
chr2_+_20967673 0.12 ENSDART00000057174
arpc5a
actin related protein 2/3 complex, subunit 5A
chr6_+_11989537 0.12 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr21_+_35215810 0.12 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr7_+_25053331 0.12 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr20_+_35433192 0.12 ENSDART00000017485
sf3b6
splicing factor 3b, subunit 6
chr17_+_25397070 0.12 ENSDART00000164254
zgc:154055
zgc:154055
chr18_+_13792490 0.12 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr21_-_43457554 0.11 ENSDART00000085039
stk26
serine/threonine protein kinase 26
chr5_+_26213874 0.11 ENSDART00000193816
ENSDART00000098514
oclnb
occludin b
chr6_+_9155271 0.11 ENSDART00000168727
zgc:64065
zgc:64065
chr5_+_28271412 0.11 ENSDART00000031727
vamp8
vesicle-associated membrane protein 8 (endobrevin)
chr24_-_37472727 0.11 ENSDART00000134152
cluap1
clusterin associated protein 1
chr3_+_44062576 0.11 ENSDART00000161277
ENSDART00000168784
nsmce1
NSE1 homolog, SMC5-SMC6 complex component
chr18_+_18982077 0.11 ENSDART00000006300
hacd3
3-hydroxyacyl-CoA dehydratase 3
chr19_+_46158078 0.11 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr5_+_67835595 0.10 ENSDART00000159386
si:ch211-271b14.1
si:ch211-271b14.1
chr7_+_26167420 0.10 ENSDART00000173941
si:ch211-196f2.6
si:ch211-196f2.6
chr21_+_15870752 0.10 ENSDART00000122015
fam169ab
family with sequence similarity 169, member Ab
chr17_+_40989973 0.10 ENSDART00000160049
mrpl33
mitochondrial ribosomal protein L33
chr16_+_54513267 0.10 ENSDART00000161923
CABZ01088508.1

chr13_+_22719789 0.10 ENSDART00000057672
nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_-_27962757 0.10 ENSDART00000147386
ece1
endothelin converting enzyme 1
chr6_+_37655078 0.10 ENSDART00000122199
ENSDART00000065127
cyfip1
cytoplasmic FMR1 interacting protein 1
chr9_+_34221997 0.10 ENSDART00000028617
mpc2
mitochondrial pyruvate carrier 2
chr16_-_22930925 0.09 ENSDART00000133819
si:dkey-246i14.3
si:dkey-246i14.3
chr11_-_6265574 0.09 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr14_+_6159162 0.09 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr10_-_5568379 0.09 ENSDART00000164558
ENSDART00000005292
syk
spleen tyrosine kinase
chr1_-_51734524 0.09 ENSDART00000109640
ENSDART00000122628
junba
JunB proto-oncogene, AP-1 transcription factor subunit a
chr21_-_22676323 0.09 ENSDART00000167392
gig2h
grass carp reovirus (GCRV)-induced gene 2h
chr8_-_49766205 0.09 ENSDART00000137941
ENSDART00000097919
ENSDART00000147309
hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr24_-_27461295 0.09 ENSDART00000110748
ccl34b.9
chemokine (C-C motif) ligand 34b, duplicate 9
chr7_-_28696556 0.09 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr19_+_10937932 0.09 ENSDART00000168968
si:ch73-347e22.8
si:ch73-347e22.8
chr11_+_14286160 0.09 ENSDART00000166236
si:ch211-262i1.3
si:ch211-262i1.3
chr9_+_13985567 0.09 ENSDART00000102296
cd28
CD28 molecule
chr13_+_39532050 0.09 ENSDART00000019379
marveld1
MARVEL domain containing 1
chr13_+_33268657 0.09 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr20_-_19858936 0.08 ENSDART00000161579
ptk2bb
protein tyrosine kinase 2 beta, b
chr12_-_4632519 0.08 ENSDART00000110514
prr12a
proline rich 12a
chr9_-_12659140 0.08 ENSDART00000058565
pttg1ipb
PTTG1 interacting protein b
chr3_-_39488482 0.08 ENSDART00000135192
zgc:100868
zgc:100868
chr18_+_20225961 0.08 ENSDART00000045679
tle3a
transducin-like enhancer of split 3a
chr23_-_33558161 0.08 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr18_+_10820430 0.08 ENSDART00000161990
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr6_+_40573365 0.08 ENSDART00000004075
uqcc2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr22_-_13165186 0.08 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr6_-_55958705 0.08 ENSDART00000155963
eya2
EYA transcriptional coactivator and phosphatase 2
chr4_+_10616626 0.08 ENSDART00000067251
ENSDART00000143690
cped1
cadherin-like and PC-esterase domain containing 1
chr3_-_16039619 0.08 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr5_-_22974641 0.08 ENSDART00000135711
si:dkey-237j10.2
si:dkey-237j10.2
chr8_-_31701157 0.08 ENSDART00000141799
fbxo4
F-box protein 4
chr6_-_34220641 0.08 ENSDART00000102391
dmrt2b
doublesex and mab-3 related transcription factor 2b
chr16_-_20870143 0.08 ENSDART00000169541
ENSDART00000040727
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr20_-_5400395 0.07 ENSDART00000168103
snw1
SNW domain containing 1
chr15_-_1484795 0.07 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr16_+_25343934 0.07 ENSDART00000109710
zfat
zinc finger and AT hook domain containing
chr1_-_26398361 0.07 ENSDART00000160183
ppa2
pyrophosphatase (inorganic) 2
chr6_+_13232934 0.07 ENSDART00000089725
ino80db
INO80 complex subunit Db
chr6_+_36821621 0.07 ENSDART00000104157
tmem45a
transmembrane protein 45a
chr2_+_37837249 0.07 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr1_-_10647307 0.07 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr3_-_4253214 0.07 ENSDART00000155807
si:dkey-175d9.2
si:dkey-175d9.2
chr4_+_76637548 0.07 ENSDART00000133799
ms4a17a.9
membrane-spanning 4-domains, subfamily A, member 17A.9
chr3_-_32275975 0.07 ENSDART00000178448
cpt1cb
carnitine palmitoyltransferase 1Cb
chr8_+_27807974 0.07 ENSDART00000078509
capza1b
capping protein (actin filament) muscle Z-line, alpha 1b
chr7_-_22941472 0.07 ENSDART00000190334
tnfsf10l
TNF superfamily member 10, like
chr9_+_26103814 0.07 ENSDART00000026011
efnb2a
ephrin-B2a
chr22_+_11153590 0.07 ENSDART00000188207
bcor
BCL6 corepressor
chr3_+_26813058 0.07 ENSDART00000055537
socs1a
suppressor of cytokine signaling 1a
chr5_+_20103085 0.07 ENSDART00000079424
si:rp71-1c23.3
si:rp71-1c23.3
chr16_+_48631412 0.07 ENSDART00000154273
pbx2
pre-B-cell leukemia homeobox 2
chr6_-_40573221 0.06 ENSDART00000157203
ENSDART00000154951
tomm6
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr22_+_5851122 0.06 ENSDART00000082044
zmp:0000001161
zmp:0000001161
chr19_+_7916790 0.06 ENSDART00000081584
si:dkey-266f7.1
si:dkey-266f7.1
chr19_+_7799036 0.06 ENSDART00000053380
hax1
HCLS1 associated protein X-1
chr12_+_38983989 0.06 ENSDART00000156673
si:ch73-181m17.1
si:ch73-181m17.1
chr17_+_33415319 0.06 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr15_+_40188076 0.06 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr17_-_23603263 0.06 ENSDART00000079559
ifit16
interferon-induced protein with tetratricopeptide repeats 16
chr2_-_22631498 0.06 ENSDART00000146425
stk25b
serine/threonine kinase 25b
chr5_-_42878178 0.06 ENSDART00000162981
CXCL11 (1 of many)
C-X-C motif chemokine ligand 11
chr2_+_45300512 0.06 ENSDART00000144704
camsap2b
calmodulin regulated spectrin-associated protein family, member 2b
chr20_+_32497260 0.06 ENSDART00000145175
ENSDART00000132921
si:ch73-257c13.2
si:ch73-257c13.2
chr25_+_15933411 0.06 ENSDART00000191581
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr16_-_26525901 0.06 ENSDART00000110260
l3mbtl1b
l(3)mbt-like 1b (Drosophila)
chr10_-_3332362 0.06 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr23_+_30736895 0.06 ENSDART00000042944
asxl1
additional sex combs like transcriptional regulator 1
chr20_-_20932760 0.06 ENSDART00000152415
ENSDART00000039907
btbd6b
BTB (POZ) domain containing 6b
chr20_+_53521648 0.06 ENSDART00000139794
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr5_+_65040228 0.06 ENSDART00000164278
pmpca
peptidase (mitochondrial processing) alpha
chr1_-_55008882 0.06 ENSDART00000083572
zgc:136864
zgc:136864
chr7_+_32369026 0.06 ENSDART00000169588
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr7_+_38770167 0.06 ENSDART00000190827
arhgap1
Rho GTPase activating protein 1
chr18_+_22217489 0.05 ENSDART00000165464
ripor1
RHO family interacting cell polarization regulator 1
chr14_+_7932973 0.05 ENSDART00000109941
cxxc5b
CXXC finger protein 5b
chr16_+_25809235 0.05 ENSDART00000181196
irgq1
immunity-related GTPase family, q1
chr1_-_40341306 0.05 ENSDART00000190649
maml3
mastermind-like transcriptional coactivator 3
chr5_-_23118290 0.05 ENSDART00000132857
uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr7_+_41313568 0.05 ENSDART00000016660
zgc:165532
zgc:165532
chr9_-_14084743 0.05 ENSDART00000056105
fer1l6
fer-1-like family member 6
chr20_+_25552057 0.05 ENSDART00000102913
cyp2v1
cytochrome P450, family 2, subfamily V, polypeptide 1
chr19_+_5418006 0.05 ENSDART00000132874
eif1b
eukaryotic translation initiation factor 1B
chr10_+_40284003 0.05 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
git2b
G protein-coupled receptor kinase interacting ArfGAP 2b
chr2_-_37837472 0.05 ENSDART00000165347
mettl17
methyltransferase like 17
chr4_+_68922112 0.05 ENSDART00000159074
si:dkey-264f17.2
si:dkey-264f17.2
chr5_+_24179307 0.05 ENSDART00000051552
mpdu1a
mannose-P-dolichol utilization defect 1a
chr19_-_17385548 0.05 ENSDART00000162383
nkiras1
NFKB inhibitor interacting Ras-like 1
chr9_+_1313418 0.05 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr12_-_35386910 0.05 ENSDART00000153453
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr20_-_26060154 0.05 ENSDART00000151950
serac1
serine active site containing 1
chr5_-_12587053 0.05 ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr13_-_49819027 0.05 ENSDART00000067824
b3galnt2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr3_-_31057624 0.05 ENSDART00000152901
armc5
armadillo repeat containing 5
chr14_+_6159356 0.05 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr2_-_37837056 0.05 ENSDART00000158179
ENSDART00000160317
ENSDART00000171409
mettl17
methyltransferase like 17
chr1_-_46981134 0.05 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr12_+_19036380 0.05 ENSDART00000153086
ENSDART00000181060
kctd17
potassium channel tetramerization domain containing 17
chr18_-_26811959 0.05 ENSDART00000086250
znf592
zinc finger protein 592
chr14_-_1200854 0.05 ENSDART00000106672
arl9
ADP-ribosylation factor-like 9
chr4_-_38281909 0.04 ENSDART00000162448
si:ch211-229l10.9
si:ch211-229l10.9
chr19_+_43822968 0.04 ENSDART00000171041
eloa
elongin A
chr8_+_23152244 0.04 ENSDART00000036801
ENSDART00000184298
slc17a9a
solute carrier family 17 (vesicular nucleotide transporter), member 9a
chr18_-_19004247 0.04 ENSDART00000135800
ints14
integrator complex subunit 14
chr14_+_11457500 0.04 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr2_+_26288301 0.04 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr8_+_19548985 0.04 ENSDART00000123104
notch2
notch 2
chr25_-_28587896 0.04 ENSDART00000111908
si:dkeyp-67e1.6
si:dkeyp-67e1.6
chr5_+_25317061 0.04 ENSDART00000170097
trpm6
transient receptor potential cation channel, subfamily M, member 6
chr19_+_40122160 0.04 ENSDART00000143966
si:ch211-173p18.3
si:ch211-173p18.3
chr25_-_24240797 0.04 ENSDART00000132790
spty2d1
SPT2 chromatin protein domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of stat3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.2 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.1 0.6 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.2 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.0 0.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.1 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.2 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.0 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.0 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane