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PRJNA207719: Tissue specific transcriptome profiling

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Results for stat4

Z-value: 0.93

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Transcription factors associated with stat4

Gene Symbol Gene ID Gene Info
stat4
ENSDARG00000028731 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat4dr11_v1_chr9_+_41156818_411568180.405.1e-01Click!

Activity profile of stat4 motif

Sorted Z-values of stat4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_26118855 1.04 ENSDART00000009028
ela3l
elastase 3 like
chr6_+_41503854 0.95 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr7_+_12950507 0.93 ENSDART00000067629
ENSDART00000158004
saa
serum amyloid A
chr2_+_4207209 0.87 ENSDART00000157903
ENSDART00000166476
gata6
GATA binding protein 6
chr22_-_13350240 0.81 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
si:ch211-227m13.1
chr13_+_13681681 0.70 ENSDART00000057825
cfd
complement factor D (adipsin)
chr21_+_45626136 0.65 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr17_-_12498096 0.65 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr4_+_76735113 0.59 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr17_-_10838434 0.58 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr21_-_22715297 0.57 ENSDART00000065548
c1qb
complement component 1, q subcomponent, B chain
chr17_+_30591287 0.52 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr21_+_25777425 0.51 ENSDART00000021620
cldnd
claudin d
chr19_+_7938121 0.50 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
si:dkey-266f7.5
chr10_-_25823258 0.47 ENSDART00000064327
ftr54
finTRIM family, member 54
chr23_+_17417539 0.46 ENSDART00000182605
BX649300.2

chr18_+_30567945 0.46 ENSDART00000078894
irf8
interferon regulatory factor 8
chr21_-_27338639 0.45 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr16_-_11859309 0.45 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr3_-_32275975 0.43 ENSDART00000178448
cpt1cb
carnitine palmitoyltransferase 1Cb
chr9_+_15890558 0.42 ENSDART00000144032
si:dkey-14o1.20
si:dkey-14o1.20
chr8_-_38159805 0.42 ENSDART00000112331
ENSDART00000180006
adgra2
adhesion G protein-coupled receptor A2
chr1_-_38171648 0.42 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr4_-_12725513 0.41 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr1_-_6085750 0.41 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr7_+_65673885 0.40 ENSDART00000169182
parvab
parvin, alpha b
chr24_-_26820698 0.40 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr16_+_38394371 0.39 ENSDART00000137954
cd83
CD83 molecule
chr3_-_34098731 0.38 ENSDART00000150999
ighv5-3
immunoglobulin heavy variable 5-3
chr5_+_37978501 0.38 ENSDART00000012050
apoa1a
apolipoprotein A-Ia
chr16_-_36834505 0.38 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
pnp4b
purine nucleoside phosphorylase 4b
chr15_+_934660 0.38 ENSDART00000154248
si:dkey-77f5.10
si:dkey-77f5.10
chr10_+_36650222 0.37 ENSDART00000126963
ucp3
uncoupling protein 3
chr8_+_39795918 0.37 ENSDART00000143413
si:ch211-170d8.2
si:ch211-170d8.2
chr21_+_39197628 0.37 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr19_+_712127 0.37 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr16_+_50289916 0.36 ENSDART00000168861
ENSDART00000167332
hamp
hepcidin antimicrobial peptide
chr16_-_21785261 0.36 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr9_-_16062938 0.36 ENSDART00000099479
crfb4
cytokine receptor family member b4
chr11_-_17964525 0.35 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr22_+_30631072 0.35 ENSDART00000059970
zmp:0000000606
zmp:0000000606
chr14_+_52323322 0.33 ENSDART00000161245
cpxm1b
carboxypeptidase X (M14 family), member 1b
chr19_+_10331325 0.33 ENSDART00000143930
tmem238a
transmembrane protein 238a
chr11_-_11882982 0.33 ENSDART00000190853
wipf2a
WAS/WASL interacting protein family, member 2a
chr10_+_8401929 0.33 ENSDART00000059028
hvcn1
hydrogen voltage-gated channel 1
chr4_+_18960914 0.33 ENSDART00000139730
impdh1b
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr18_-_3527686 0.33 ENSDART00000169049
capn5a
calpain 5a
chr5_-_42883761 0.32 ENSDART00000167374
BX323596.2

chr5_-_57624425 0.32 ENSDART00000167892
zgc:193711
zgc:193711
chr20_+_37294112 0.32 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr12_+_26435918 0.32 ENSDART00000006908
itgb3b
integrin beta 3b
chr3_+_36646054 0.32 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr24_-_26485098 0.32 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr9_+_41218967 0.32 ENSDART00000000280
ENSDART00000145674
stat1b
signal transducer and activator of transcription 1b
chr18_-_3527988 0.32 ENSDART00000157669
capn5a
calpain 5a
chr8_+_28467893 0.32 ENSDART00000189724
slc52a3
solute carrier family 52 (riboflavin transporter), member 3
chr16_-_36099492 0.31 ENSDART00000180905
CU499336.2

chr4_-_13518381 0.31 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr2_+_45159855 0.31 ENSDART00000056333
CU929150.1

chr5_-_42878178 0.31 ENSDART00000162981
CXCL11 (1 of many)
C-X-C motif chemokine ligand 11
chr13_-_31647323 0.30 ENSDART00000135381
six4a
SIX homeobox 4a
chr2_+_26288301 0.30 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr13_+_2908764 0.30 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr7_+_33133547 0.30 ENSDART00000191967
si:ch211-194p6.7
si:ch211-194p6.7
chr12_-_37299646 0.30 ENSDART00000146142
ENSDART00000085201
pmp22b
peripheral myelin protein 22b
chr16_-_27564256 0.30 ENSDART00000078297
zgc:153215
zgc:153215
chr2_-_42035250 0.29 ENSDART00000056460
ENSDART00000140788
gbp1
guanylate binding protein 1
chr2_+_42005217 0.29 ENSDART00000143562
gbp2
guanylate binding protein 2
chr1_+_12195700 0.28 ENSDART00000040307
tdrd7a
tudor domain containing 7 a
chr11_+_43401201 0.28 ENSDART00000190128
vipb
vasoactive intestinal peptide b
chr9_+_29616854 0.28 ENSDART00000033902
ENSDART00000143493
phf11
PHD finger protein 11
chr24_-_17039638 0.28 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr16_-_9830451 0.27 ENSDART00000148528
grhl2a
grainyhead-like transcription factor 2a
chr25_+_11281970 0.27 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr15_+_5088210 0.27 ENSDART00000183423
mxf
myxovirus (influenza virus) resistance F
chr3_-_41292569 0.27 ENSDART00000111856
sdk1a
sidekick cell adhesion molecule 1a
chr2_+_4402765 0.27 ENSDART00000159525
bambib
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr9_+_29992271 0.26 ENSDART00000188199
cmss1
cms1 ribosomal small subunit homolog (yeast)
chr15_+_27387555 0.26 ENSDART00000018603
tbx4
T-box 4
chr9_-_27738110 0.26 ENSDART00000060347
crygs2
crystallin, gamma S2
chr2_-_50707494 0.26 ENSDART00000081711
CABZ01053221.1

chr25_+_16312258 0.26 ENSDART00000064187
parvaa
parvin, alpha a
chr5_+_22393501 0.25 ENSDART00000185276
si:dkey-27p18.7
si:dkey-27p18.7
chr25_-_27842654 0.25 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr6_-_54179860 0.25 ENSDART00000164283
rps10
ribosomal protein S10
chr7_-_60096318 0.25 ENSDART00000189125
BX511067.1

chr6_-_7439490 0.25 ENSDART00000188825
fkbp11
FK506 binding protein 11
chr5_+_19261687 0.25 ENSDART00000139401
atp8b5a
ATPase phospholipid transporting 8B5a
chr7_-_69121896 0.24 ENSDART00000130227
crispld2
cysteine-rich secretory protein LCCL domain containing 2
chr3_+_3852614 0.24 ENSDART00000184334
ENSDART00000162313
si:ch73-338o16.4
si:ch73-338o16.4
chr23_+_1216215 0.24 ENSDART00000165957
utrn
utrophin
chr1_+_12177195 0.24 ENSDART00000146842
ENSDART00000142081
stra6l
STRA6-like
chr15_+_20529197 0.24 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr3_-_3439150 0.23 ENSDART00000021286
A2ML1 (1 of many)
si:dkey-46g23.5
chr21_+_39197418 0.23 ENSDART00000076000
cpdb
carboxypeptidase D, b
chr15_-_18200358 0.23 ENSDART00000158569
si:ch211-247l8.8
si:ch211-247l8.8
chr9_+_44994214 0.23 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr14_+_24241241 0.23 ENSDART00000022377
nkx2.5
NK2 homeobox 5
chr4_+_76637548 0.23 ENSDART00000133799
ms4a17a.9
membrane-spanning 4-domains, subfamily A, member 17A.9
chr16_-_17188294 0.23 ENSDART00000165883
opn9
opsin 9
chr7_+_26167420 0.23 ENSDART00000173941
si:ch211-196f2.6
si:ch211-196f2.6
chr5_-_42071505 0.23 ENSDART00000137224
ENSDART00000193721
cxcl11.7
cenpv
chemokine (C-X-C motif) ligand 11, duplicate 7
centromere protein V
chr5_+_19261391 0.22 ENSDART00000089173
atp8b5a
ATPase phospholipid transporting 8B5a
chr5_+_43870389 0.22 ENSDART00000141002
zgc:112966
zgc:112966
chr11_+_14286160 0.22 ENSDART00000166236
si:ch211-262i1.3
si:ch211-262i1.3
chr12_-_9796237 0.22 ENSDART00000149344
prdm9
PR domain containing 9
chr12_-_26408876 0.21 ENSDART00000105636
myoz1b
myozenin 1b
chr8_+_25351863 0.21 ENSDART00000034092
dnase1l1l
deoxyribonuclease I-like 1-like
chr25_-_1348370 0.20 ENSDART00000154865
itga11b
integrin, alpha 11b
chr21_-_11970199 0.20 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr11_+_43401592 0.20 ENSDART00000112468
vipb
vasoactive intestinal peptide b
chr6_+_52947186 0.20 ENSDART00000155831
uba7
ubiquitin-like modifier activating enzyme 7
chr2_-_42091926 0.20 ENSDART00000142663
si:dkey-97a13.12
si:dkey-97a13.12
chr5_+_20421539 0.20 ENSDART00000164499
selplg
selectin P ligand
chr15_-_5245726 0.20 ENSDART00000174079
ENSDART00000174041
or128-1
odorant receptor, family E, subfamily 128, member 1
chr3_-_43954971 0.20 ENSDART00000167159
ENSDART00000189315
ubfd1
ubiquitin family domain containing 1
chr6_+_52938534 0.20 ENSDART00000174150
BX649282.2

chr8_-_11067079 0.20 ENSDART00000181986
dennd2c
DENN/MADD domain containing 2C
chr22_-_13165186 0.20 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr7_-_26924903 0.20 ENSDART00000124363
alx4a
ALX homeobox 4a
chr7_-_28696556 0.20 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr19_+_19762183 0.20 ENSDART00000163611
ENSDART00000187604
hoxa3a
homeobox A3a
chr14_-_33278084 0.19 ENSDART00000132850
stard14
START domain containing 14
chr5_+_23256187 0.19 ENSDART00000168717
ENSDART00000142915
si:dkey-125i10.3
si:dkey-125i10.3
chr2_-_10098191 0.19 ENSDART00000138081
bcl6ab
B-cell CLL/lymphoma 6a, genome duplicate b
chr18_-_20444296 0.19 ENSDART00000132993
kif23
kinesin family member 23
chr21_+_6397463 0.19 ENSDART00000136539
si:ch211-225g23.1
si:ch211-225g23.1
chr2_-_43942595 0.19 ENSDART00000147925
si:ch211-195h23.4
si:ch211-195h23.4
chr22_-_28645676 0.18 ENSDART00000005883
jagn1b
jagunal homolog 1b
chr22_+_26263290 0.18 ENSDART00000184840
BX649315.1

chr21_+_19834072 0.18 ENSDART00000147555
ccdc80l2
coiled-coil domain containing 80 like 2
chr13_+_24851102 0.18 ENSDART00000187637
si:dkey-24f15.2
si:dkey-24f15.2
chr6_+_18321627 0.18 ENSDART00000183107
ENSDART00000189715
card14
caspase recruitment domain family, member 14
chr24_-_25256670 0.17 ENSDART00000126270
hhla2b.1
HERV-H LTR-associating 2b, tandem duplicate 1
chr13_+_19871646 0.17 ENSDART00000176239
CT027674.1

chr21_+_42713845 0.17 ENSDART00000166927
si:ch1073-204b8.1
si:ch1073-204b8.1
chr1_+_37391716 0.17 ENSDART00000191986
sparcl1
SPARC-like 1
chr20_+_6493648 0.17 ENSDART00000099846
mep1b
meprin A, beta
chr21_-_40049642 0.17 ENSDART00000124416
med31
mediator complex subunit 31
chr18_+_33171765 0.17 ENSDART00000064153
si:ch73-125k17.2
si:ch73-125k17.2
chr15_+_11883804 0.17 ENSDART00000163255
gpr184
G protein-coupled receptor 184
chr23_-_38160024 0.17 ENSDART00000087112
pfdn4
prefoldin subunit 4
chr19_+_19761966 0.17 ENSDART00000163697
hoxa3a
homeobox A3a
chr19_-_3821678 0.17 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr1_-_24458057 0.17 ENSDART00000140197
ENSDART00000181286
sh3d19
SH3 domain containing 19
chr23_+_43718115 0.16 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr6_-_30689126 0.16 ENSDART00000065211
pars2
prolyl-tRNA synthetase 2, mitochondrial
chr20_-_43775495 0.16 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matn3a
matrilin 3a
chr14_+_33329420 0.16 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr15_-_18176694 0.16 ENSDART00000189840
tmprss5
transmembrane protease, serine 5
chr14_-_52433292 0.16 ENSDART00000164272
rest
RE1-silencing transcription factor
chr14_-_22015232 0.16 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr2_-_9989919 0.16 ENSDART00000180213
ENSDART00000184369
imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr7_-_3630019 0.15 ENSDART00000138164
ENSDART00000064277
si:dkey-192d15.3
si:dkey-192d15.3
chr12_-_17028255 0.15 ENSDART00000152678
ifit10
interferon-induced protein with tetratricopeptide repeats 10
chr6_+_39923052 0.15 ENSDART00000149019
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr17_-_45386823 0.15 ENSDART00000156002
tmem206
transmembrane protein 206
chr16_+_21789703 0.15 ENSDART00000153617
trim108
tripartite motif containing 108
chr8_-_810556 0.15 ENSDART00000140793
loxhd1b
lipoxygenase homology domains 1b
chr1_-_18585046 0.15 ENSDART00000147228
fam114a1
family with sequence similarity 114, member A1
chr17_-_45386546 0.15 ENSDART00000182647
tmem206
transmembrane protein 206
chr12_-_30338779 0.15 ENSDART00000192511
vwa2
von Willebrand factor A domain containing 2
chr25_+_32390794 0.15 ENSDART00000012600
galk2
galactokinase 2
chr4_-_61920018 0.15 ENSDART00000164832
znf1056
zinc finger protein 1056
chr5_-_37959874 0.15 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr14_+_45970033 0.15 ENSDART00000047716
fermt3b
fermitin family member 3b
chr6_-_31364475 0.15 ENSDART00000145715
ENSDART00000134370
ak4
adenylate kinase 4
chr8_+_41048501 0.14 ENSDART00000123288
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr16_+_9713850 0.14 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr9_+_27354653 0.14 ENSDART00000134134
tlr20.2
toll-like receptor 20, tandem duplicate 2
chr21_-_32060993 0.14 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr7_+_48870496 0.14 ENSDART00000009642
igf2a
insulin-like growth factor 2a
chr24_+_13635387 0.14 ENSDART00000105997
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr23_-_33558161 0.14 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr2_+_42005475 0.14 ENSDART00000056461
gbp2
guanylate binding protein 2
chr1_+_58400409 0.14 ENSDART00000111526
si:ch73-59p9.2
si:ch73-59p9.2
chr7_+_32693890 0.14 ENSDART00000121972
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr16_-_31717851 0.13 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr13_-_5257303 0.13 ENSDART00000110610
si:dkey-78p8.1
si:dkey-78p8.1
chr8_-_20838342 0.13 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr8_-_46060685 0.13 ENSDART00000121902
pimr188
Pim proto-oncogene, serine/threonine kinase, related 188
chr8_-_47212686 0.13 ENSDART00000040370
pimr189
Pim proto-oncogene, serine/threonine kinase, related 189
chr14_-_14566417 0.12 ENSDART00000159056
si:dkey-27i16.2
si:dkey-27i16.2
chr11_-_6974022 0.12 ENSDART00000172851
COMP
si:ch211-43f4.1
chr7_-_50764714 0.12 ENSDART00000110283
iqgap1
IQ motif containing GTPase activating protein 1
chr13_+_9213805 0.12 ENSDART00000131455
pimr158
Pim proto-oncogene, serine/threonine kinase, related 158
chr4_+_63254033 0.12 ENSDART00000170121
si:ch211-258f1.3
si:ch211-258f1.3
chr16_-_31718013 0.12 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular
chr3_+_58119571 0.12 ENSDART00000108979
si:ch211-256e16.4
si:ch211-256e16.4
chr20_-_40729364 0.12 ENSDART00000101014
cx32.2
connexin 32.2
chr5_+_36895545 0.12 ENSDART00000135776
ENSDART00000147561
ENSDART00000133842
ENSDART00000051185
ENSDART00000141984
ENSDART00000136301
ENSDART00000142388
srsf7a
serine/arginine-rich splicing factor 7a
chr15_-_23721618 0.12 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr7_+_4854690 0.12 ENSDART00000131645
si:dkey-28d5.7
si:dkey-28d5.7
chr15_-_22251089 0.11 ENSDART00000153646
si:ch211-286b4.4
si:ch211-286b4.4
chr8_-_18203274 0.11 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
elovl8b
ELOVL fatty acid elongase 8b
chr9_-_21936841 0.11 ENSDART00000144843
lmo7a
LIM domain 7a
chr7_-_6468611 0.11 ENSDART00000147978
hist1h2a11
histone cluster 1 H2A family member 11
chr3_-_13599482 0.11 ENSDART00000166639
tufm
Tu translation elongation factor, mitochondrial
chr16_-_22585289 0.10 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr7_+_15266093 0.10 ENSDART00000124676
sv2ba
synaptic vesicle glycoprotein 2Ba

Network of associatons between targets according to the STRING database.

First level regulatory network of stat4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.9 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.2 1.2 GO:0001909 leukocyte mediated cytotoxicity(GO:0001909)
0.2 0.5 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.4 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.1 0.4 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.1 0.5 GO:0060406 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.3 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 0.4 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.2 GO:0097676 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.2 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.7 GO:0002831 regulation of response to biotic stimulus(GO:0002831) regulation of defense response to virus(GO:0050688)
0.1 0.2 GO:1903430 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.3 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.4 GO:0032570 response to progesterone(GO:0032570)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.3 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.1 GO:0060844 arterial endothelial cell fate commitment(GO:0060844)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.2 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.3 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.2 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.0 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.1 GO:0070973 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.8 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.5 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.0 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0019814 immunoglobulin complex(GO:0019814)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation