Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for stat5a+stat5b

Z-value: 0.53

Motif logo

logo of

Transcription factors associated with stat5a+stat5b

Gene Symbol Gene ID Gene Info
stat5a
ENSDARG00000019392 signal transducer and activator of transcription 5a
stat5b
ENSDARG00000055588 signal transducer and activator of transcription 5b
stat5a
ENSDARG00000113871 signal transducer and activator of transcription 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat5bdr11_v1_chr12_-_13650344_13650472-0.894.4e-02Click!
stat5adr11_v1_chr3_+_17251542_17251542-0.266.8e-01Click!

Activity profile of stat5a+stat5b motif

Sorted Z-values of stat5a+stat5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41503854 0.51 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr14_+_6953244 0.44 ENSDART00000159470
rack1
receptor for activated C kinase 1
chr11_-_17964525 0.41 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr14_-_6987649 0.38 ENSDART00000060990
eif4ebp3l
eukaryotic translation initiation factor 4E binding protein 3, like
chr2_-_51794472 0.37 ENSDART00000186652
BX908782.3

chr12_-_37299646 0.34 ENSDART00000146142
ENSDART00000085201
pmp22b
peripheral myelin protein 22b
chr3_+_55100045 0.33 ENSDART00000113098
hbaa1
hemoglobin, alpha adult 1
chr25_+_31323978 0.31 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr20_+_25586099 0.29 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr24_-_25166720 0.29 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr6_-_53048291 0.28 ENSDART00000103267
fam212ab
family with sequence similarity 212, member Ab
chr3_-_32541033 0.28 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr24_-_25166416 0.25 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr2_+_7192966 0.25 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr10_-_41352502 0.23 ENSDART00000052971
ENSDART00000128156
rab11fip1b
RAB11 family interacting protein 1 (class I) b
chr23_+_26017227 0.22 ENSDART00000002939
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr20_+_37294112 0.21 ENSDART00000076293
ENSDART00000140450
cx23
connexin 23
chr2_-_42109575 0.20 ENSDART00000075551
adhfe1
alcohol dehydrogenase, iron containing, 1
chr22_+_36914636 0.20 ENSDART00000150948
pimr205
Pim proto-oncogene, serine/threonine kinase, related 205
chr15_-_32383340 0.20 ENSDART00000185632
c4
complement component 4
chr25_+_13620555 0.20 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr8_-_42624454 0.20 ENSDART00000075550
kazald3
Kazal-type serine peptidase inhibitor domain 3
chr12_-_23365737 0.20 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr5_-_4245186 0.18 ENSDART00000145912
si:ch211-283g2.3
si:ch211-283g2.3
chr8_+_19548985 0.18 ENSDART00000123104
notch2
notch 2
chr5_-_42878178 0.18 ENSDART00000162981
CXCL11 (1 of many)
C-X-C motif chemokine ligand 11
chr2_+_22659787 0.18 ENSDART00000043956
zgc:161973
zgc:161973
chr6_-_16804001 0.17 ENSDART00000155398
pimr40
Pim proto-oncogene, serine/threonine kinase, related 40
chr25_-_27842654 0.17 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr18_-_48558420 0.15 ENSDART00000058987
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr19_-_32804535 0.14 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr15_-_32383529 0.14 ENSDART00000028349
c4
complement component 4
chr7_+_29890292 0.14 ENSDART00000170403
ENSDART00000168600
tln2a
talin 2a
chr1_-_9195629 0.14 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr23_+_7518294 0.13 ENSDART00000081536
hck
HCK proto-oncogene, Src family tyrosine kinase
chr10_-_43568239 0.13 ENSDART00000131731
ENSDART00000097433
ENSDART00000131309
mef2ca
myocyte enhancer factor 2ca
chr11_+_16040680 0.13 ENSDART00000157703
agtrap
angiotensin II receptor-associated protein
chr19_-_12648408 0.13 ENSDART00000103692
fam210aa
family with sequence similarity 210, member Aa
chr7_+_33133547 0.12 ENSDART00000191967
si:ch211-194p6.7
si:ch211-194p6.7
chr17_+_46864116 0.12 ENSDART00000156250
pimr27
Pim proto-oncogene, serine/threonine kinase, related 27
chr6_+_16870004 0.12 ENSDART00000154794
pimr21
Pim proto-oncogene, serine/threonine kinase, related 21
chr22_-_16180467 0.12 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr6_+_39923052 0.12 ENSDART00000149019
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr5_-_42883761 0.12 ENSDART00000167374
BX323596.2

chr19_-_12648122 0.12 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr13_-_17464654 0.12 ENSDART00000140312
lrmda
leucine rich melanocyte differentiation associated
chr6_-_43677125 0.11 ENSDART00000150128
foxp1b
forkhead box P1b
chr8_-_45838481 0.11 ENSDART00000148206
ENSDART00000170485
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr8_-_46060685 0.11 ENSDART00000121902
pimr188
Pim proto-oncogene, serine/threonine kinase, related 188
chr4_-_5863906 0.11 ENSDART00000169424
slc5a8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr8_-_47212686 0.11 ENSDART00000040370
pimr189
Pim proto-oncogene, serine/threonine kinase, related 189
chr19_+_25504645 0.11 ENSDART00000143292
col28a1a
collagen, type XXVIII, alpha 1a
chr16_-_41787421 0.11 ENSDART00000147210
si:dkey-199f5.8
si:dkey-199f5.8
chr2_-_42035250 0.10 ENSDART00000056460
ENSDART00000140788
gbp1
guanylate binding protein 1
chr4_+_34599803 0.10 ENSDART00000134088
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr17_+_6536152 0.10 ENSDART00000062952
ENSDART00000121789
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr4_-_57571688 0.10 ENSDART00000160179
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr7_+_17560808 0.10 ENSDART00000159699
ENSDART00000165724
ENSDART00000129017
ENSDART00000101955
nitr1b
novel immune-type receptor 1b
chr17_-_6536305 0.10 ENSDART00000154855
cenpo
centromere protein O
chr13_-_25284716 0.10 ENSDART00000039828
vcla
vinculin a
chr13_-_9335891 0.10 ENSDART00000080637
BX901922.1

chr7_+_34786591 0.10 ENSDART00000173700
si:dkey-148a17.5
si:dkey-148a17.5
chr25_+_6186823 0.10 ENSDART00000153526
oaz2a
ornithine decarboxylase antizyme 2a
chr6_+_16895685 0.10 ENSDART00000154090
pimr28
Pim proto-oncogene, serine/threonine kinase, related 28
chr20_-_3238110 0.09 ENSDART00000008077
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr19_+_15443063 0.09 ENSDART00000151732
lin28a
lin-28 homolog A (C. elegans)
chr4_-_57572054 0.09 ENSDART00000158610
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr14_+_22132388 0.09 ENSDART00000109065
ccng1
cyclin G1
chr11_+_16040517 0.09 ENSDART00000111284
agtrap
angiotensin II receptor-associated protein
chr2_-_14793343 0.09 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr24_+_13635387 0.09 ENSDART00000105997
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr5_-_42071505 0.09 ENSDART00000137224
ENSDART00000193721
cxcl11.7
cenpv
chemokine (C-X-C motif) ligand 11, duplicate 7
centromere protein V
chr22_+_5851122 0.09 ENSDART00000082044
zmp:0000001161
zmp:0000001161
chr7_+_58751504 0.09 ENSDART00000024185
zgc:56231
zgc:56231
chr6_-_17052116 0.08 ENSDART00000156825
pimr45
Pim proto-oncogene, serine/threonine kinase, related 45
chr6_-_17266221 0.08 ENSDART00000155448
pimr18
Pim proto-oncogene, serine/threonine kinase, related 18
chr11_+_30321116 0.08 ENSDART00000187921
ENSDART00000127075
ugt1b1
UDP glucuronosyltransferase 1 family, polypeptide B1
chr4_+_13586455 0.08 ENSDART00000187230
tnpo3
transportin 3
chr17_+_12255642 0.08 ENSDART00000155175
pimr175
Pim proto-oncogene, serine/threonine kinase, related 175
chr17_-_46817295 0.08 ENSDART00000155904
pimr24
Pim proto-oncogene, serine/threonine kinase, related 24
chr12_+_38983989 0.08 ENSDART00000156673
si:ch73-181m17.1
si:ch73-181m17.1
chr9_+_1313418 0.07 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr15_-_44052927 0.07 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr18_-_49318823 0.07 ENSDART00000098419
sb:cb81
sb:cb81
chr1_-_10647307 0.07 ENSDART00000103548
si:dkey-31e10.1
si:dkey-31e10.1
chr25_-_30394746 0.07 ENSDART00000185346
si:ch211-93f2.1
si:ch211-93f2.1
chr17_-_46933567 0.07 ENSDART00000157274
pimr25
Pim proto-oncogene, serine/threonine kinase, related 25
chr4_+_49322310 0.06 ENSDART00000184154
ENSDART00000167162
BX942819.1

chr3_+_49021079 0.06 ENSDART00000162012
zgc:163083
zgc:163083
chr6_-_16735402 0.06 ENSDART00000154216
pimr44
Pim proto-oncogene, serine/threonine kinase, related 44
chr10_-_24868581 0.06 ENSDART00000193055
CABZ01058107.1

chr10_+_44700103 0.06 ENSDART00000165999
scarb1
scavenger receptor class B, member 1
chr15_+_2857556 0.06 ENSDART00000157758
mre11a
MRE11 homolog A, double strand break repair nuclease
chr11_+_30314885 0.06 ENSDART00000187418
ENSDART00000123244
ugt1b2
UDP glucuronosyltransferase 1 family, polypeptide B2
chr5_+_29160324 0.06 ENSDART00000137324
dpp7
dipeptidyl-peptidase 7
chr2_-_3611960 0.06 ENSDART00000184579
pter
phosphotriesterase related
chr2_+_37140448 0.06 ENSDART00000045016
ENSDART00000142940
pex19
peroxisomal biogenesis factor 19
chr20_+_28803977 0.06 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr12_-_30338779 0.05 ENSDART00000192511
vwa2
von Willebrand factor A domain containing 2
chr17_-_43517542 0.05 ENSDART00000133665
mrpl35
mitochondrial ribosomal protein L35
chr7_+_65813301 0.05 ENSDART00000187449
ENSDART00000179834
ENSDART00000082740
ENSDART00000178627
tead1b
TEA domain family member 1b
chr15_+_37412883 0.05 ENSDART00000156474
zbtb32
zinc finger and BTB domain containing 32
chr7_-_13362590 0.05 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr7_-_11605185 0.05 ENSDART00000169291
ENSDART00000113904
stard5
StAR-related lipid transfer (START) domain containing 5
chr1_-_10647484 0.05 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr17_-_23631400 0.05 ENSDART00000079563
fas
Fas cell surface death receptor
chr24_-_18477672 0.05 ENSDART00000126928
ENSDART00000158393
si:dkey-73n8.3
si:dkey-73n8.3
chr17_-_6536466 0.05 ENSDART00000188735
cenpo
centromere protein O
chr23_-_1571682 0.05 ENSDART00000013635
fbxo30b
F-box protein 30b
chr17_+_11372531 0.05 ENSDART00000130975
ENSDART00000149366
timm9
translocase of inner mitochondrial membrane 9 homolog
chr7_-_38687431 0.04 ENSDART00000074490
aplnr2
apelin receptor 2
chr15_-_41290415 0.04 ENSDART00000152157
si:dkey-75b17.1
si:dkey-75b17.1
chr11_+_36409457 0.04 ENSDART00000077641
cyb561d1
cytochrome b561 family, member D1
chr15_-_3282220 0.04 ENSDART00000092942
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr6_-_43283122 0.04 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr4_+_57580303 0.04 ENSDART00000166492
ENSDART00000103025
ENSDART00000170786
il17ra1b
il17ra2
interleukin 17 receptor A1b
interleukin 17 receptor A2
chr15_-_25039083 0.03 ENSDART00000154409
pimr190
Pim proto-oncogene, serine/threonine kinase, related 190
chr7_+_17106160 0.03 ENSDART00000190048
ENSDART00000180004
ENSDART00000013409
prmt3
protein arginine methyltransferase 3
chr23_-_37432459 0.03 ENSDART00000188916
zmp:0000001088
zmp:0000001088
chr17_-_24521382 0.03 ENSDART00000092948
peli1b
pellino E3 ubiquitin protein ligase 1b
chr1_+_57040472 0.03 ENSDART00000181365
si:ch211-1f22.16
si:ch211-1f22.16
chr4_-_49952636 0.03 ENSDART00000157941
si:dkey-156k2.3
si:dkey-156k2.3
chr15_-_6966221 0.03 ENSDART00000165487
ENSDART00000027657
mrps22
mitochondrial ribosomal protein S22
chr22_+_7480465 0.02 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr1_+_33322174 0.02 ENSDART00000140435
mxra5a
matrix-remodelling associated 5a
chr20_+_46897504 0.02 ENSDART00000158124
si:ch73-21k16.1
si:ch73-21k16.1
chr2_-_37140423 0.02 ENSDART00000144220
tspan37
tetraspanin 37
chr10_+_44699734 0.02 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr18_-_20444296 0.02 ENSDART00000132993
kif23
kinesin family member 23
chr24_+_31374324 0.02 ENSDART00000172335
ENSDART00000163162
cpne3
copine III
chr6_-_18393476 0.01 ENSDART00000168309
trim25
tripartite motif containing 25
chr22_-_9861531 0.01 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr3_+_26905024 0.01 ENSDART00000077835
dexi
Dexi homolog (mouse)
chr22_-_10774735 0.01 ENSDART00000081156
timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr1_-_7582859 0.00 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr19_-_43757568 0.00 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr15_-_25083200 0.00 ENSDART00000156053
pimr191
Pim proto-oncogene, serine/threonine kinase, related 191
chr21_-_32284532 0.00 ENSDART00000190676
clk4b
CDC-like kinase 4b
chr20_+_17581881 0.00 ENSDART00000182832
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr4_-_685412 0.00 ENSDART00000168167
rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr4_+_47174366 0.00 ENSDART00000170732
si:dkey-26m3.1
si:dkey-26m3.1
chr7_+_53254234 0.00 ENSDART00000169830
trip4
thyroid hormone receptor interactor 4
chr1_+_33322555 0.00 ENSDART00000113486
mxra5a
matrix-remodelling associated 5a

Network of associatons between targets according to the STRING database.

First level regulatory network of stat5a+stat5b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.4 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.1 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.0 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0034553 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.0 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis