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PRJNA207719: Tissue specific transcriptome profiling

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Results for tbx15_tbx1_mgaa_tbx4

Z-value: 2.05

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Transcription factors associated with tbx15_tbx1_mgaa_tbx4

Gene Symbol Gene ID Gene Info
tbx15
ENSDARG00000002582 T-box transcription factor 15
tbx1
ENSDARG00000031891 T-box transcription factor 1
mgaa
ENSDARG00000078784 MAX dimerization protein MGA a
tbx4
ENSDARG00000030058 T-box transcription factor 4
tbx4
ENSDARG00000113067 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mgaadr11_v1_chr17_+_10566490_105664950.932.2e-02Click!
tbx15dr11_v1_chr9_-_21067673_210676730.592.9e-01Click!
tbx4dr11_v1_chr15_+_27384798_273847980.444.6e-01Click!
tbx1dr11_v1_chr5_+_15203421_15203421-0.395.2e-01Click!

Activity profile of tbx15_tbx1_mgaa_tbx4 motif

Sorted Z-values of tbx15_tbx1_mgaa_tbx4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_37837245 4.95 ENSDART00000171617
epd
ependymin
chr25_+_37397031 3.28 ENSDART00000193643
ENSDART00000169132
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr7_-_38612230 2.69 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr24_-_6158933 2.61 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr23_-_4855122 2.59 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr10_-_31782616 2.09 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr21_-_43550120 1.86 ENSDART00000151627
si:ch73-362m14.2
si:ch73-362m14.2
chr19_+_14921000 1.75 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr25_+_7784582 1.72 ENSDART00000155016
dgkzb
diacylglycerol kinase, zeta b
chr22_-_20575679 1.70 ENSDART00000089033
lingo3a
leucine rich repeat and Ig domain containing 3a
chr16_-_12173399 1.66 ENSDART00000142574
clstn3
calsyntenin 3
chr5_-_33215261 1.64 ENSDART00000097935
ENSDART00000134777
si:dkey-226m8.10
si:dkey-226m8.10
chr7_+_7048245 1.62 ENSDART00000001649
actn3b
actinin alpha 3b
chr3_-_61205711 1.59 ENSDART00000055062
pvalb1
parvalbumin 1
chr13_-_27653679 1.59 ENSDART00000142568
rims1a
regulating synaptic membrane exocytosis 1a
chr5_-_46896541 1.58 ENSDART00000133240
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr16_+_30301539 1.51 ENSDART00000186018
LO017848.1

chr16_-_12173554 1.50 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr7_+_30867008 1.50 ENSDART00000193106
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr16_-_13109749 1.49 ENSDART00000142610
prkcg
protein kinase C, gamma
chr16_-_29437373 1.45 ENSDART00000148405
si:ch211-113g11.6
si:ch211-113g11.6
chr7_+_6969909 1.38 ENSDART00000189886
actn3b
actinin alpha 3b
chr18_-_20822045 1.38 ENSDART00000100743
cttnbp2
cortactin binding protein 2
chr9_+_34334156 1.36 ENSDART00000144272
pou2f1b
POU class 2 homeobox 1b
chr21_-_43949208 1.35 ENSDART00000150983
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr23_+_28582865 1.34 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr12_-_35386910 1.32 ENSDART00000153453
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr16_-_17207754 1.31 ENSDART00000063804
wu:fj39g12
wu:fj39g12
chr15_-_16098531 1.28 ENSDART00000080377
aldoca
aldolase C, fructose-bisphosphate, a
chr17_+_27176243 1.21 ENSDART00000162527
si:ch211-160f23.7
si:ch211-160f23.7
chr2_-_32501501 1.19 ENSDART00000181309
faim2a
Fas apoptotic inhibitory molecule 2a
chr14_-_26177156 1.18 ENSDART00000014149
fat2
FAT atypical cadherin 2
chr11_+_25583950 1.17 ENSDART00000111961
ccdc120
coiled-coil domain containing 120
chr18_+_22302635 1.14 ENSDART00000141051
carmil2
capping protein regulator and myosin 1 linker 2
chr5_+_22791686 1.11 ENSDART00000014806
npas2
neuronal PAS domain protein 2
chr11_+_23933016 1.11 ENSDART00000000486
cntn2
contactin 2
chr13_+_4205724 1.10 ENSDART00000134105
dlk2
delta-like 2 homolog (Drosophila)
chr22_+_11857356 1.08 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr10_-_31562695 1.07 ENSDART00000186456
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr21_+_44300689 1.02 ENSDART00000186298
ENSDART00000142810
gabra3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr1_+_8662530 1.01 ENSDART00000054989
fscn1b
fascin actin-bundling protein 1b
chr19_+_47311869 1.01 ENSDART00000136647
ext1c
exostoses (multiple) 1c
chr16_+_50741154 1.00 ENSDART00000101627
IGLON5
zgc:110372
chr3_-_33901483 0.98 ENSDART00000144774
ENSDART00000138765
cacna1aa
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a
chr6_+_40587551 0.96 ENSDART00000155554
frs3
fibroblast growth factor receptor substrate 3
chr22_-_14475927 0.90 ENSDART00000135768
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr17_+_28340138 0.90 ENSDART00000033943
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr21_-_10488379 0.89 ENSDART00000163878
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr23_-_30431333 0.88 ENSDART00000146633
camta1a
calmodulin binding transcription activator 1a
chr7_-_51476276 0.88 ENSDART00000082464
nhsl2
NHS-like 2
chr22_-_12160283 0.86 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr15_-_18432673 0.85 ENSDART00000146853
ncam1b
neural cell adhesion molecule 1b
chr5_+_59449762 0.85 ENSDART00000150230
clip2
CAP-GLY domain containing linker protein 2
chr21_-_39628771 0.84 ENSDART00000183995
aldocb
aldolase C, fructose-bisphosphate, b
chr18_-_51015718 0.83 ENSDART00000190698
LO018598.1

chr1_-_23110740 0.83 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr1_-_8101495 0.81 ENSDART00000161938
si:dkeyp-9d4.3
si:dkeyp-9d4.3
chr6_+_13606410 0.81 ENSDART00000104716
asic4b
acid-sensing (proton-gated) ion channel family member 4b
chr13_-_36264861 0.80 ENSDART00000100204
slc8a3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr3_-_33469722 0.79 ENSDART00000151539
sgsm3
small G protein signaling modulator 3
chr20_-_15922210 0.79 ENSDART00000152412
ENSDART00000152354
ENSDART00000152828
ENSDART00000013453
ENSDART00000152357
fam20b
family with sequence similarity 20, member B (H. sapiens)
chr16_+_5702749 0.79 ENSDART00000138330
zgc:158689
zgc:158689
chr9_+_32978302 0.77 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr20_+_41549200 0.77 ENSDART00000135715
fam184a
family with sequence similarity 184, member A
chr19_-_5812319 0.76 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr7_+_46368520 0.76 ENSDART00000192821
znf536
zinc finger protein 536
chr13_-_21739142 0.75 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr13_-_24880525 0.75 ENSDART00000136624
kat6b
K(lysine) acetyltransferase 6B
chr12_-_26383242 0.75 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr2_+_33368414 0.74 ENSDART00000077462
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_-_55675617 0.74 ENSDART00000021009
ENSDART00000188631
cbfa2t3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr11_+_1628538 0.73 ENSDART00000154967
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr1_-_40341306 0.73 ENSDART00000190649
maml3
mastermind-like transcriptional coactivator 3
chr5_+_32228538 0.72 ENSDART00000077471
myhc4
myosin heavy chain 4
chr23_+_40604951 0.71 ENSDART00000114959
cdh24a
cadherin 24, type 2a
chr22_-_15385442 0.70 ENSDART00000090975
tmem264
transmembrane protein 264
chr14_+_6605675 0.70 ENSDART00000143179
adam19b
ADAM metallopeptidase domain 19b
chr19_+_32947910 0.69 ENSDART00000052091
atp6v1c1b
ATPase H+ transporting V1 subunit C1b
chr13_-_30027730 0.69 ENSDART00000044009
scdb
stearoyl-CoA desaturase b
chr4_-_4795205 0.69 ENSDART00000039313
zgc:162331
zgc:162331
chr16_+_53203370 0.69 ENSDART00000154669
si:ch211-269k10.2
si:ch211-269k10.2
chr9_-_41323746 0.68 ENSDART00000140564
glsb
glutaminase b
chr4_-_19016396 0.67 ENSDART00000166160
si:dkey-31f5.11
si:dkey-31f5.11
chr19_-_28360033 0.67 ENSDART00000186994
si:dkey-261i16.5
si:dkey-261i16.5
chr13_-_24906307 0.66 ENSDART00000148191
ENSDART00000189810
kat6b
K(lysine) acetyltransferase 6B
chr17_-_20394566 0.66 ENSDART00000154667
sorcs3b
sortilin related VPS10 domain containing receptor 3b
chr20_+_41549735 0.66 ENSDART00000184235
fam184a
family with sequence similarity 184, member A
chr23_+_45584223 0.66 ENSDART00000149367
si:ch73-290k24.5
si:ch73-290k24.5
chr18_-_13360106 0.65 ENSDART00000091512
cmip
c-Maf inducing protein
chr4_+_11384891 0.65 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr3_-_25814097 0.63 ENSDART00000169706
ntn1b
netrin 1b
chr12_-_5448993 0.63 ENSDART00000181802
tbc1d12b
TBC1 domain family, member 12b
chr14_+_50770537 0.63 ENSDART00000158723
sncb
synuclein, beta
chr12_+_32292564 0.61 ENSDART00000152945
ANKFN1
si:ch211-277e21.2
chr18_+_19419120 0.61 ENSDART00000025107
map2k1
mitogen-activated protein kinase kinase 1
chr20_+_21268795 0.61 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr21_+_26726936 0.61 ENSDART00000065392
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr5_-_45894802 0.59 ENSDART00000097648
crfb6
cytokine receptor family member b6
chr22_-_34872533 0.59 ENSDART00000167176
slit1b
slit homolog 1b (Drosophila)
chr4_-_60049792 0.59 ENSDART00000158199
znf1033
zinc finger protein 1033
chr17_-_3986236 0.59 ENSDART00000188794
ENSDART00000160830
PLCB1
si:ch1073-140o9.2
chr21_-_25685422 0.58 ENSDART00000182921
phkg1b
phosphorylase kinase, gamma 1b (muscle)
chr9_+_42095220 0.58 ENSDART00000148317
ENSDART00000134431
pcbp3
poly(rC) binding protein 3
chr9_+_17438765 0.58 ENSDART00000138953
rgcc
regulator of cell cycle
chr13_+_11439486 0.57 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr8_+_47571211 0.57 ENSDART00000131460
plch2a
phospholipase C, eta 2a
chr10_+_18952271 0.57 ENSDART00000146517
dpysl2b
dihydropyrimidinase-like 2b
chr11_+_41540862 0.57 ENSDART00000173210
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr12_-_17147473 0.57 ENSDART00000106035
stambpl1
STAM binding protein-like 1
chr14_+_45406299 0.56 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr19_+_22727940 0.56 ENSDART00000052509
trhrb
thyrotropin-releasing hormone receptor b
chr19_+_14059349 0.55 ENSDART00000166230
tpbga
trophoblast glycoprotein a
chr7_-_32599669 0.55 ENSDART00000173752
kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr3_-_42016693 0.55 ENSDART00000184741
ttyh3a
tweety family member 3a
chr3_+_33367954 0.55 ENSDART00000103161
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr1_-_53750522 0.54 ENSDART00000190755
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr8_+_13364950 0.54 ENSDART00000159760
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr15_+_28482862 0.54 ENSDART00000015286
ENSDART00000154320
ankrd13b
ankyrin repeat domain 13B
chr5_+_28398449 0.53 ENSDART00000165292
nsmfb
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr20_-_28800999 0.53 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr10_+_37500234 0.52 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr14_+_50937757 0.52 ENSDART00000163865
rnf44
ring finger protein 44
chr5_+_42467867 0.52 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr2_+_23823622 0.52 ENSDART00000099581
si:dkey-24c2.9
si:dkey-24c2.9
chr1_-_714626 0.51 ENSDART00000161072
adamts5
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr4_+_11375894 0.50 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr14_+_45925810 0.50 ENSDART00000189543
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr3_-_25813426 0.50 ENSDART00000039482
ntn1b
netrin 1b
chr1_+_37195465 0.50 ENSDART00000043855
ENSDART00000192580
ENSDART00000181666
dclk2a
doublecortin-like kinase 2a
chr19_+_37458610 0.49 ENSDART00000103151
dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr11_-_21303946 0.48 ENSDART00000185786
RASSF5
si:dkey-85p17.3
chr25_-_12788370 0.48 ENSDART00000158551
slc7a5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr17_-_26537928 0.48 ENSDART00000155692
ENSDART00000122366
ccser2a
coiled-coil serine-rich protein 2a
chr11_-_26832685 0.47 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr23_+_24611747 0.47 ENSDART00000134978
nckap5l
NCK-associated protein 5-like
chr14_-_33872092 0.47 ENSDART00000111903
si:ch73-335m24.2
si:ch73-335m24.2
chr15_+_42397125 0.47 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr8_-_1838315 0.46 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr24_+_39158283 0.46 ENSDART00000053139
atp6v0cb
ATPase H+ transporting V0 subunit cb
chr14_-_31059218 0.45 ENSDART00000111691
ENSDART00000021379
ENSDART00000113479
mbnl3
muscleblind-like splicing regulator 3
chr1_-_17663108 0.45 ENSDART00000131559
si:dkey-256e7.5
si:dkey-256e7.5
chr5_-_37875636 0.44 ENSDART00000184674
arhgap35b
Rho GTPase activating protein 35b
chr18_+_45796096 0.43 ENSDART00000087070
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr2_-_37893910 0.43 ENSDART00000143027
hbl2
hexose-binding lectin 2
chr17_-_14726824 0.43 ENSDART00000162947
si:ch73-305o9.3
si:ch73-305o9.3
chr21_+_33503835 0.43 ENSDART00000125658
clint1b
clathrin interactor 1b
chr24_-_36095526 0.42 ENSDART00000158145
CABZ01075509.1

chr5_+_26075230 0.42 ENSDART00000098473
klf9
Kruppel-like factor 9
chr1_-_30039331 0.42 ENSDART00000086935
ENSDART00000143800
MARCH4 (1 of many)
zgc:153256
chr11_-_37880492 0.42 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr9_-_21970067 0.42 ENSDART00000009920
lmo7a
LIM domain 7a
chr13_-_39830816 0.42 ENSDART00000138981
zgc:171482
zgc:171482
chr16_-_13613475 0.41 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr21_-_2217685 0.41 ENSDART00000159315
si:dkey-50i6.5
si:dkey-50i6.5
chr6_-_16394528 0.41 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr14_-_32744464 0.41 ENSDART00000075617
sox3
SRY (sex determining region Y)-box 3
chr13_-_33822550 0.40 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr8_-_19246342 0.40 ENSDART00000147172
abhd17ab
abhydrolase domain containing 17Ab
chr8_+_54055390 0.40 ENSDART00000102696
magi1a
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr7_-_18656069 0.40 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr9_-_18877597 0.40 ENSDART00000099446
kctd4
potassium channel tetramerization domain containing 4
chr10_+_43994471 0.39 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr19_+_13375838 0.39 ENSDART00000163093
lrp12
low density lipoprotein receptor-related protein 12
chr7_+_11197022 0.39 ENSDART00000185236
cemip
cell migration inducing protein, hyaluronan binding
chr15_+_40665310 0.39 ENSDART00000154187
ENSDART00000042082
fat3a
FAT atypical cadherin 3a
chr3_+_23488652 0.39 ENSDART00000126282
nr1d1
nuclear receptor subfamily 1, group d, member 1
chr13_+_2894536 0.39 ENSDART00000183678
CABZ01087629.1

chr2_-_16224083 0.39 ENSDART00000165953
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr11_-_12998400 0.38 ENSDART00000018614
chrna4b
cholinergic receptor, nicotinic, alpha 4b
chr2_+_24203229 0.38 ENSDART00000138088
map4l
microtubule associated protein 4 like
chr14_-_33872616 0.38 ENSDART00000162840
si:ch73-335m24.2
si:ch73-335m24.2
chr2_+_24199276 0.38 ENSDART00000140575
map4l
microtubule associated protein 4 like
chr10_-_20588787 0.38 ENSDART00000138045
ENSDART00000181885
ENSDART00000091115
nsd3
nuclear receptor binding SET domain protein 3
chr22_-_21755524 0.38 ENSDART00000149635
tle2b
transducin like enhancer of split 2b
chr5_+_62052538 0.38 ENSDART00000141574
si:dkey-35m8.1
si:dkey-35m8.1
chr8_+_1651821 0.37 ENSDART00000060865
ENSDART00000186304
rasal1b
RAS protein activator like 1b (GAP1 like)
chr13_+_30054996 0.37 ENSDART00000110061
ENSDART00000186045
spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr8_-_21268303 0.37 ENSDART00000067211
gpr37l1b
G protein-coupled receptor 37 like 1b
chr6_+_58406014 0.37 ENSDART00000044241
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr23_+_27912079 0.37 ENSDART00000171859
BX539336.1

chr18_+_6536293 0.37 ENSDART00000024576
fkbp4
FK506 binding protein 4
chr22_+_1300587 0.37 ENSDART00000124161
si:ch73-138e16.5
si:ch73-138e16.5
chr8_+_8532407 0.37 ENSDART00000169276
ENSDART00000138993
grm6a
glutamate receptor, metabotropic 6a
chr24_+_26039464 0.37 ENSDART00000131017
tnk2a
tyrosine kinase, non-receptor, 2a
chr14_+_35691889 0.36 ENSDART00000074685
glrbb
glycine receptor, beta b
chr24_+_14713776 0.36 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr16_+_50100420 0.36 ENSDART00000128167
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr14_+_790166 0.36 ENSDART00000123912
adra2da
adrenergic, alpha-2D-, receptor a
chr10_+_42462577 0.36 ENSDART00000133463
npy8ar
neuropeptide Y receptor Y8a
chr17_+_9009098 0.36 ENSDART00000180856
akap6
A kinase (PRKA) anchor protein 6
chr14_-_48187742 0.36 ENSDART00000129871
rxfp1
relaxin/insulin-like family peptide receptor 1
chr3_+_16449490 0.36 ENSDART00000141467
kcnj12b
potassium inwardly-rectifying channel, subfamily J, member 12b
chr13_+_18276187 0.35 ENSDART00000141009
tet1
tet methylcytosine dioxygenase 1
chr18_-_893574 0.35 ENSDART00000150959
parp6a
poly (ADP-ribose) polymerase family, member 6a
chr10_-_26430168 0.35 ENSDART00000128894
dchs1b
dachsous cadherin-related 1b
chr15_-_21669618 0.35 ENSDART00000156995
sorl1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_+_58211 0.35 ENSDART00000157642
si:ch1073-209e23.1
si:ch1073-209e23.1
chr1_-_51606552 0.35 ENSDART00000130828
cnrip1a
cannabinoid receptor interacting protein 1a
chr10_-_8032885 0.34 ENSDART00000188619
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr11_+_30161168 0.34 ENSDART00000157385
cdkl5
cyclin-dependent kinase-like 5

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx15_tbx1_mgaa_tbx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 1.8 GO:0060074 synapse maturation(GO:0060074)
0.4 1.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.4 3.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 1.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.4 1.1 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3 0.9 GO:0021611 facial nerve formation(GO:0021611)
0.2 0.7 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 0.7 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.5 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.2 4.0 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.7 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 1.1 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 2.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.5 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.3 GO:0015824 proline transport(GO:0015824)
0.1 0.8 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.3 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.1 0.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.3 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.7 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.9 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0098725 somatic stem cell population maintenance(GO:0035019) symmetric cell division(GO:0098725)
0.1 1.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.4 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.3 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.3 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.2 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.6 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.2 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.0 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.3 GO:0048714 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) regulation of oligodendrocyte differentiation(GO:0048713) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0035094 response to nicotine(GO:0035094)
0.0 4.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 1.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975)
0.0 1.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.9 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.0 1.3 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.6 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 1.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0002834 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.8 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 1.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 3.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.3 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.2 GO:0001964 startle response(GO:0001964)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 1.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.5 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0060031 mediolateral intercalation(GO:0060031)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.6 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.2 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0021871 forebrain regionalization(GO:0021871)
0.0 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.3 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.6 GO:0016573 histone acetylation(GO:0016573)
0.0 1.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063) regulation of protein deacetylation(GO:0090311)
0.0 0.1 GO:0042311 vasodilation(GO:0042311)
0.0 0.0 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.5 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.2 1.6 GO:0016586 RSC complex(GO:0016586)
0.2 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.1 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.6 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 0.3 GO:0097268 cytoophidium(GO:0097268)
0.1 0.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.2 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.3 GO:0033503 HULC complex(GO:0033503)
0.1 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.0 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 2.9 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.1 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 9.0 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 6.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.0 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 8.1 GO:0043005 neuron projection(GO:0043005)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.6 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.7 GO:0005770 late endosome(GO:0005770)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 2.9 GO:0005764 lysosome(GO:0005764)
0.0 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 1.7 GO:0038046 enkephalin receptor activity(GO:0038046)
0.3 1.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.6 GO:1903136 cuprous ion binding(GO:1903136)
0.2 2.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.6 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 0.7 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 3.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.0 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.7 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.1 1.6 GO:0009931 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 1.3 GO:0005112 Notch binding(GO:0005112)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.4 GO:0016933 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 1.4 GO:0019003 GDP binding(GO:0019003)
0.0 1.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.5 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 4.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 19.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.3 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:0004952 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 3.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 3.4 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.3 PID IFNG PATHWAY IFN-gamma pathway
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 2.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters