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PRJNA207719: Tissue specific transcriptome profiling

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Results for tbx5a+tbx5b

Z-value: 0.78

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Transcription factors associated with tbx5a+tbx5b

Gene Symbol Gene ID Gene Info
tbx5a
ENSDARG00000024894 T-box transcription factor 5a
tbx5b
ENSDARG00000092060 T-box transcription factor 5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx5adr11_v1_chr5_-_72289648_722896480.089.0e-01Click!
tbx5bdr11_v1_chr5_+_23152282_23152282-0.029.8e-01Click!

Activity profile of tbx5a+tbx5b motif

Sorted Z-values of tbx5a+tbx5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25187210 0.83 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
si:dkey-183i3.5
chr21_+_30351256 0.76 ENSDART00000078341
foxi3a
forkhead box I3a
chr6_+_40794015 0.73 ENSDART00000144479
gata2b
GATA binding protein 2b
chr23_-_10175898 0.69 ENSDART00000146185
krt5
keratin 5
chr1_-_59104145 0.68 ENSDART00000132495
ENSDART00000152457
MFAP4 (1 of many)
si:zfos-2330d3.7
si:zfos-2330d3.1
si:zfos-2330d3.7
chr6_+_56141852 0.59 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr17_+_26965351 0.56 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr19_-_5332784 0.55 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr17_+_2549503 0.54 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr23_-_10254288 0.51 ENSDART00000081215
krt8
keratin 8
chr11_-_12198765 0.51 ENSDART00000104203
ENSDART00000128364
ENSDART00000166887
ENSDART00000041533
krt95
kertain 95
chr11_+_29537756 0.50 ENSDART00000103388
wu:fi42e03
wu:fi42e03
chr3_-_32603191 0.49 ENSDART00000150997
si:ch73-248e21.7
si:ch73-248e21.7
chr16_+_3982590 0.49 ENSDART00000149295
zc3h12a
zinc finger CCCH-type containing 12A
chr8_+_2478862 0.48 ENSDART00000131739
si:dkeyp-51b9.3
si:dkeyp-51b9.3
chr3_+_13624815 0.48 ENSDART00000161451
pglyrp6
peptidoglycan recognition protein 6
chr16_-_30878521 0.44 ENSDART00000141403
dennd3b
DENN/MADD domain containing 3b
chr15_-_945804 0.43 ENSDART00000063257
alox5b.1
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr5_+_57658898 0.42 ENSDART00000074268
ENSDART00000124568
zgc:153929
zgc:153929
chr17_-_53359028 0.42 ENSDART00000185218
CABZ01068208.1

chr7_+_15329819 0.42 ENSDART00000006018
mespaa
mesoderm posterior aa
chr24_-_10006158 0.42 ENSDART00000106244
zgc:171750
zgc:171750
chr19_+_791538 0.42 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr2_-_32237916 0.41 ENSDART00000141418
fam49ba
family with sequence similarity 49, member Ba
chr7_-_54320088 0.41 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr18_+_23373683 0.40 ENSDART00000001102
ENSDART00000189030
mctp2a
multiple C2 domains, transmembrane 2a
chr5_+_26213874 0.40 ENSDART00000193816
ENSDART00000098514
oclnb
occludin b
chr14_+_48862987 0.40 ENSDART00000167810
zgc:154054
zgc:154054
chr3_+_36275633 0.39 ENSDART00000185027
ENSDART00000149532
ENSDART00000102883
ENSDART00000148444
zgc:86896
zgc:86896
chr24_-_10021341 0.38 ENSDART00000137250
zgc:173856
zgc:173856
chr12_-_46228023 0.38 ENSDART00000153455
si:ch211-226h7.6
si:ch211-226h7.6
chr10_+_19596214 0.38 ENSDART00000183110
CABZ01059626.1

chr1_+_54655160 0.38 ENSDART00000190319
si:ch211-202h22.7
si:ch211-202h22.7
chr2_-_28396993 0.37 ENSDART00000188170
CABZ01056052.1

chr2_+_36007449 0.37 ENSDART00000161837
lamc2
laminin, gamma 2
chr19_+_19777437 0.36 ENSDART00000170662
hoxa3a
homeobox A3a
chr11_-_25853212 0.36 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr21_+_25226558 0.36 ENSDART00000168480
sycn.2
syncollin, tandem duplicate 2
chr11_-_40504170 0.36 ENSDART00000165394
si:dkeyp-61b2.1
si:dkeyp-61b2.1
chr24_-_9997948 0.36 ENSDART00000136274
si:ch211-146l10.7
si:ch211-146l10.7
chr23_+_44614056 0.35 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr23_-_26535875 0.35 ENSDART00000135988
si:dkey-205h13.2
si:dkey-205h13.2
chr3_+_5331428 0.34 ENSDART00000156561
si:ch73-106l15.4
si:ch73-106l15.4
chr3_+_5297493 0.34 ENSDART00000138596
si:ch211-150d5.3
si:ch211-150d5.3
chr3_+_32526799 0.33 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr1_-_7603734 0.33 ENSDART00000009315
mxb
myxovirus (influenza) resistance B
chr12_-_36045283 0.32 ENSDART00000160646
gprc5c
G protein-coupled receptor, class C, group 5, member C
chr23_-_5719453 0.32 ENSDART00000033093
lad1
ladinin
chr14_+_21934331 0.32 ENSDART00000123225
zgc:113229
zgc:113229
chr3_+_32099507 0.32 ENSDART00000044238
zgc:92066
zgc:92066
chr24_+_10027902 0.32 ENSDART00000175961
ENSDART00000172773
si:ch211-146l10.8
si:ch211-146l10.8
chr3_+_43086548 0.32 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr6_-_436658 0.32 ENSDART00000191515
grap2b
GRB2-related adaptor protein 2b
chr3_+_32526263 0.31 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr5_+_6670945 0.31 ENSDART00000185686
pxna
paxillin a
chr10_+_19569052 0.31 ENSDART00000058425
CABZ01059627.1

chr13_+_18533005 0.30 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr2_+_2470687 0.30 ENSDART00000184024
ENSDART00000061955
myl13
myosin, light chain 13
chr21_-_41025340 0.30 ENSDART00000148231
plac8l1
PLAC8-like 1
chr16_-_31469065 0.30 ENSDART00000182397
si:ch211-251p5.5
si:ch211-251p5.5
chr10_+_19595009 0.30 ENSDART00000112276
zgc:173837
zgc:173837
chr15_-_1590858 0.29 ENSDART00000081875
nnr
nanor
chr13_-_34858500 0.28 ENSDART00000184843
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr21_-_34972872 0.28 ENSDART00000023838
lipia
lipase, member Ia
chr4_+_14981854 0.28 ENSDART00000067046
cax1
cation/H+ exchanger protein 1
chr1_+_21563311 0.28 ENSDART00000147076
ENSDART00000006147
primpol
primase and polymerase (DNA-directed)
chr21_-_28439596 0.27 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_27347076 0.27 ENSDART00000173383
fbln2
fibulin 2
chr8_-_24252933 0.27 ENSDART00000057624
zgc:110353
zgc:110353
chr19_-_34999379 0.27 ENSDART00000051751
zgc:113424
zgc:113424
chr8_-_20243389 0.27 ENSDART00000184904
acer1
alkaline ceramidase 1
chr13_+_23623346 0.27 ENSDART00000057619
il22ra2
interleukin 22 receptor, alpha 2
chr23_+_19790962 0.26 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr1_+_40308077 0.26 ENSDART00000138992
vwa10.2
von Willebrand factor A domain containing 10, tandem duplicate 2
chr7_-_38638809 0.26 ENSDART00000144341
c6ast4
six-cysteine containing astacin protease 4
chr17_-_6349044 0.26 ENSDART00000081707
oct2
organic cation transporter 2
chr22_-_18164835 0.26 ENSDART00000143189
rfxank
regulatory factor X-associated ankyrin-containing protein
chr3_-_15451097 0.26 ENSDART00000163836
BX784026.1
Danio rerio linker for activation of T cells (lat), mRNA.
chr10_+_38610741 0.25 ENSDART00000126444
mmp13a
matrix metallopeptidase 13a
chr19_+_4076259 0.25 ENSDART00000160633
zgc:173581
zgc:173581
chr2_+_11028923 0.25 ENSDART00000076725
acot11a
acyl-CoA thioesterase 11a
chr2_-_14793343 0.25 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr3_-_53508580 0.25 ENSDART00000073978
zgc:171711
zgc:171711
chr15_-_43164591 0.24 ENSDART00000171305
ap1s3a
adaptor-related protein complex 1, sigma 3 subunit, a
chr22_-_18164671 0.24 ENSDART00000014057
rfxank
regulatory factor X-associated ankyrin-containing protein
chr4_-_11594202 0.24 ENSDART00000002682
net1
neuroepithelial cell transforming 1
chr9_+_17306162 0.24 ENSDART00000075926
scel
sciellin
chr23_-_27101600 0.24 ENSDART00000139231
stat6
signal transducer and activator of transcription 6, interleukin-4 induced
chr3_+_29510818 0.24 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
rac2
Rac family small GTPase 2
chr15_+_32711663 0.24 ENSDART00000157854
ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr20_+_35857399 0.24 ENSDART00000102611
cd2ap
CD2-associated protein
chr15_-_36365840 0.24 ENSDART00000192926
si:dkey-23k10.3
si:dkey-23k10.3
chr3_+_19621034 0.23 ENSDART00000025358
itgb3a
integrin beta 3a
chr4_-_72468168 0.23 ENSDART00000182995
ENSDART00000174067
CR788316.1

chr8_-_38317914 0.23 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr16_+_26774182 0.23 ENSDART00000042895
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr7_+_57109214 0.23 ENSDART00000135068
ENSDART00000098412
enosf1
enolase superfamily member 1
chr23_-_31266586 0.23 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr14_-_28568107 0.23 ENSDART00000042850
ENSDART00000145502
insb
preproinsulin b
chr8_+_49570884 0.23 ENSDART00000182117
ENSDART00000108613
rasef
RAS and EF-hand domain containing
chr22_-_17653143 0.23 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr10_-_35149513 0.23 ENSDART00000063434
ENSDART00000131291
ripk4
receptor-interacting serine-threonine kinase 4
chr4_-_67799941 0.23 ENSDART00000185830
si:ch211-66c13.1
si:ch211-66c13.1
chr13_-_7031033 0.23 ENSDART00000193211
CABZ01061524.1

chr5_+_61476014 0.23 ENSDART00000050906
lrwd1
leucine-rich repeats and WD repeat domain containing 1
chr5_+_9360394 0.22 ENSDART00000124642
FP236810.2

chr22_-_17652914 0.22 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr15_+_32711172 0.22 ENSDART00000163936
ENSDART00000168135
postnb
periostin, osteoblast specific factor b
chr17_+_24843401 0.22 ENSDART00000110179
cx34.4
connexin 34.4
chr11_-_11575070 0.22 ENSDART00000142208
zgc:110712
zgc:110712
chr20_-_43743700 0.22 ENSDART00000100620
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr23_+_23232136 0.22 ENSDART00000126479
ENSDART00000187764
plekhn1
pleckstrin homology domain containing, family N member 1
chr3_+_12748038 0.22 ENSDART00000181174
cyp2k21
cytochrome P450, family 2, subfamily k, polypeptide 21
chr1_+_58205904 0.22 ENSDART00000147324
si:dkey-222h21.12
si:dkey-222h21.12
chr1_+_24355515 0.22 ENSDART00000051763
rps3a
ribosomal protein S3A
chr2_+_17181777 0.22 ENSDART00000112063
ptger4c
prostaglandin E receptor 4 (subtype EP4) c
chr24_+_27511734 0.21 ENSDART00000105771
cxcl32b.1
chemokine (C-X-C motif) ligand 32b, duplicate 1
chr25_-_6049339 0.21 ENSDART00000075184
snx1a
sorting nexin 1a
chr20_+_51104367 0.21 ENSDART00000073981
eif2s1b
eukaryotic translation initiation factor 2, subunit 1 alpha b
chr3_+_47245764 0.21 ENSDART00000193581
tnfsf14
TNF superfamily member 14
chr8_+_20918207 0.21 ENSDART00000144039
si:ch73-196i15.5
si:ch73-196i15.5
chr2_+_9560740 0.21 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr10_-_11376491 0.21 ENSDART00000145346
plac8.2
placenta-specific 8, tandem duplicate 2
chr24_-_39701027 0.21 ENSDART00000146491
igl3v2
immunoglobulin light 3 variable 2
chr9_-_44948488 0.21 ENSDART00000059228
vil1
villin 1
chr23_-_26536055 0.21 ENSDART00000182719
si:dkey-205h13.2
si:dkey-205h13.2
chr3_+_58656312 0.21 ENSDART00000148094
FP016018.1

chr8_-_38201415 0.21 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr7_+_5007310 0.20 ENSDART00000146083
si:ch211-272h9.3
si:ch211-272h9.3
chr5_-_68022631 0.20 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr13_-_37180815 0.20 ENSDART00000139907
si:dkeyp-77c8.1
si:dkeyp-77c8.1
chr7_-_55648336 0.20 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
pabpn1l
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr23_-_16734009 0.20 ENSDART00000125449
si:ch211-224l10.4
si:ch211-224l10.4
chr19_-_34995629 0.20 ENSDART00000141704
si:rp71-45k5.2
si:rp71-45k5.2
chr11_+_36683859 0.20 ENSDART00000170102
si:ch211-11c3.12
si:ch211-11c3.12
chr15_+_20530649 0.20 ENSDART00000186312
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr8_-_3312384 0.20 ENSDART00000035965
fut9b
fucosyltransferase 9b
chr10_-_13116337 0.20 ENSDART00000164568
musk
muscle, skeletal, receptor tyrosine kinase
chr3_-_3939785 0.20 ENSDART00000049593
unm_sa1506
un-named sa1506
chr13_+_27232848 0.20 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr7_+_15324830 0.20 ENSDART00000189088
mespaa
mesoderm posterior aa
chr23_-_40194732 0.20 ENSDART00000164931
tgm1l2
transglutaminase 1 like 2
chr3_+_58663942 0.20 ENSDART00000192794
CU571382.4

chr3_+_12848123 0.19 ENSDART00000166689
si:ch211-8c17.4
si:ch211-8c17.4
chr4_-_28334464 0.19 ENSDART00000123617
celsr1a
cadherin EGF LAG seven-pass G-type receptor 1a
chr10_-_15849027 0.19 ENSDART00000184682
tjp2a
tight junction protein 2a (zona occludens 2)
chr18_+_45666489 0.19 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr20_+_52546186 0.19 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr17_+_35362851 0.19 ENSDART00000137659
cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr16_+_30316177 0.19 ENSDART00000109505
tmem79b
transmembrane protein 79b
chr4_-_77216726 0.19 ENSDART00000099943
psmb10
proteasome subunit beta 10
chr3_+_26345732 0.19 ENSDART00000128613
rps15a
ribosomal protein S15a
chr1_-_6085750 0.19 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr25_-_35169303 0.18 ENSDART00000193240
ano9a
anoctamin 9a
chr2_+_11029138 0.18 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acot11a
acyl-CoA thioesterase 11a
chr24_-_27419198 0.18 ENSDART00000141124
ccl34b.4
chemokine (C-C motif) ligand 34b, duplicate 4
chr5_-_16475374 0.18 ENSDART00000134274
ENSDART00000136004
piwil2
piwi-like RNA-mediated gene silencing 2
chr11_-_396724 0.18 ENSDART00000184375
CR855375.3

chr12_+_26491637 0.18 ENSDART00000087036
armc7
armadillo repeat containing 7
chr9_-_25094181 0.18 ENSDART00000132160
rubcnl
RUN and cysteine rich domain containing beclin 1 interacting protein like
chr17_-_15611744 0.18 ENSDART00000010496
fhl5
four and a half LIM domains 5
chr3_-_336299 0.18 ENSDART00000105021
mhc1zfa
major histocompatibility complex class I ZFA
chr25_+_8418522 0.18 ENSDART00000189106
muc5.2
mucin 5.2
chr7_-_5070794 0.18 ENSDART00000097877
ltb4r2a
leukotriene B4 receptor 2a
chr4_-_77114795 0.18 ENSDART00000144849
CU467646.2

chr14_-_17121676 0.18 ENSDART00000170154
ENSDART00000060479
smtnl1
smoothelin-like 1
chr7_+_26545911 0.18 ENSDART00000135313
tnk1
tyrosine kinase, non-receptor, 1
chr15_+_13984879 0.18 ENSDART00000159438
zgc:162730
zgc:162730
chr21_+_39197628 0.18 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr3_-_32611833 0.18 ENSDART00000151282
si:ch73-248e21.5
si:ch73-248e21.5
chr25_+_8356707 0.18 ENSDART00000153708
muc5.1
mucin 5.1, oligomeric mucus/gel-forming
chr8_-_36412936 0.17 ENSDART00000159276
si:zfos-2070c2.3
si:zfos-2070c2.3
chr9_+_20869166 0.17 ENSDART00000147892
wdr3
WD repeat domain 3
chr13_-_50341004 0.17 ENSDART00000038120
cacul1
CDK2 associated cullin domain 1
chr12_+_20641102 0.17 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr21_-_3700334 0.17 ENSDART00000137844
atp8b1
ATPase phospholipid transporting 8B1
chr24_+_35564668 0.17 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr19_+_5640504 0.17 ENSDART00000179987
ft2
alpha(1,3)fucosyltransferase gene 2
chr6_+_28294113 0.17 ENSDART00000136898
lpp
LIM domain containing preferred translocation partner in lipoma
chr11_+_24729346 0.17 ENSDART00000087740
zgc:153953
zgc:153953
chr20_-_33566640 0.17 ENSDART00000159729
si:dkey-65b13.9
si:dkey-65b13.9
chr12_+_31616412 0.17 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr10_-_45029041 0.17 ENSDART00000167878
polm
polymerase (DNA directed), mu
chr8_+_39570615 0.17 ENSDART00000142557
lzts1
leucine zipper, putative tumor suppressor 1
chr12_+_28749189 0.17 ENSDART00000013980
tbx21
T-box 21
chr12_-_29305533 0.17 ENSDART00000189410
sh2d4bb
SH2 domain containing 4Bb
chr3_+_16762483 0.16 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr20_-_22778394 0.16 ENSDART00000152645
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr17_+_8212477 0.16 ENSDART00000064665
slc18b1
solute carrier family 18, subfamily B, member 1
chr5_-_42083363 0.16 ENSDART00000162596
cxcl11.5
chemokine (C-X-C motif) ligand 11, duplicate 5
chr5_+_55221593 0.16 ENSDART00000073638
tmc2a
transmembrane channel-like 2a
chr4_-_11106856 0.16 ENSDART00000150764
BX784029.3

chr6_+_36877968 0.16 ENSDART00000155187
traf3ip2l
TRAF3 interacting protein 2-like
chr8_-_23884301 0.16 ENSDART00000185509
ENSDART00000147202
lhfpl5b
LHFPL tetraspan subfamily member 5b
chr19_-_3741602 0.16 ENSDART00000170301
btr22
bloodthirsty-related gene family, member 22
chr9_-_98982 0.16 ENSDART00000147882
lims2
LIM and senescent cell antigen-like domains 2
chr15_-_36727462 0.16 ENSDART00000085971
nphs1
nephrosis 1, congenital, Finnish type (nephrin)
chr6_+_23057311 0.16 ENSDART00000026448
evpla
envoplakin a
chr17_+_3124129 0.16 ENSDART00000155323
zgc:136872
zgc:136872
chr3_+_52953489 0.16 ENSDART00000125136
dsn1
DSN1 homolog, MIS12 kinetochore complex component

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx5a+tbx5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.2 0.8 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.5 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.1 0.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.4 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.2 GO:0070459 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.2 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.5 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.2 GO:0072672 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0032369 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
0.0 0.6 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.5 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0090008 convergent extension involved in nephron morphogenesis(GO:0072045) hypoblast development(GO:0090008)
0.0 0.2 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.4 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:1905072 cardiac jelly development(GO:1905072)
0.0 0.3 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.0 0.1 GO:0061032 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.3 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.3 GO:0016203 muscle attachment(GO:0016203)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0030237 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.1 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.0 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.4 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0010747 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.0 0.0 GO:0055024 regulation of cardiac muscle tissue development(GO:0055024)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0010172 embryonic body morphogenesis(GO:0010172)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0045095 keratin filament(GO:0045095)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.2 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.0 GO:0030689 Noc complex(GO:0030689)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.4 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.1 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.0 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs