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PRJNA207719: Tissue specific transcriptome profiling

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Results for thraa+thrab

Z-value: 0.72

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Transcription factors associated with thraa+thrab

Gene Symbol Gene ID Gene Info
thraa
ENSDARG00000000151 thyroid hormone receptor alpha a
thrab
ENSDARG00000052654 thyroid hormone receptor alpha b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
thrabdr11_v1_chr12_-_22039350_22039350-0.266.8e-01Click!
thraadr11_v1_chr3_-_34717882_347178820.168.0e-01Click!

Activity profile of thraa+thrab motif

Sorted Z-values of thraa+thrab motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_8340886 0.39 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr16_+_50289916 0.38 ENSDART00000168861
ENSDART00000167332
hamp
hepcidin antimicrobial peptide
chr5_-_23277385 0.37 ENSDART00000134982
plp1b
proteolipid protein 1b
chr5_-_23277939 0.34 ENSDART00000003514
plp1b
proteolipid protein 1b
chr2_-_127945 0.33 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr13_-_31435137 0.32 ENSDART00000057441
rtn1a
reticulon 1a
chr20_+_30490682 0.30 ENSDART00000184871
myt1la
myelin transcription factor 1-like, a
chr5_+_38462121 0.30 ENSDART00000144425
gltpd2
glycolipid transfer protein domain containing 2
chr20_-_40717900 0.29 ENSDART00000181663
cx43
connexin 43
chr23_-_4855122 0.27 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr7_+_27455321 0.26 ENSDART00000148417
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr14_+_36738069 0.26 ENSDART00000105590
tdo2a
tryptophan 2,3-dioxygenase a
chr25_+_16895294 0.25 ENSDART00000159773
zgc:77158
zgc:77158
chr16_-_45327616 0.25 ENSDART00000158733
si:dkey-33i11.1
si:dkey-33i11.1
chr5_-_56412262 0.22 ENSDART00000083079
acaca
acetyl-CoA carboxylase alpha
chr21_-_13051613 0.22 ENSDART00000190777
myorg
myogenesis regulating glycosidase (putative)
chr4_+_17280868 0.21 ENSDART00000145349
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr2_-_32643738 0.20 ENSDART00000112452
si:dkeyp-73d8.9
si:dkeyp-73d8.9
chr9_-_374693 0.20 ENSDART00000166571
si:dkey-11f4.7
si:dkey-11f4.7
chr4_-_77432218 0.20 ENSDART00000158683
slco1d1
solute carrier organic anion transporter family, member 1D1
chr20_+_5564042 0.20 ENSDART00000090934
ENSDART00000127050
nrxn3b
neurexin 3b
chr19_-_103289 0.19 ENSDART00000143118
adgrb1b
adhesion G protein-coupled receptor B1b
chr17_-_15149192 0.19 ENSDART00000180511
ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr18_+_36037223 0.19 ENSDART00000144410
tmem91
transmembrane protein 91
chr14_-_30390145 0.19 ENSDART00000045423
slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr10_-_30785501 0.18 ENSDART00000020054
opcml
opioid binding protein/cell adhesion molecule-like
chr6_+_22068589 0.18 ENSDART00000151205
aldh1l1
aldehyde dehydrogenase 1 family, member L1
chr11_-_34147205 0.18 ENSDART00000173216
atp13a3
ATPase 13A3
chr1_-_30039331 0.18 ENSDART00000086935
ENSDART00000143800
MARCH4 (1 of many)
zgc:153256
chr16_+_5774977 0.18 ENSDART00000134202
ccka
cholecystokinin a
chr7_+_20017211 0.18 ENSDART00000100808
bcl6b
B-cell CLL/lymphoma 6, member B
chr17_+_23300827 0.18 ENSDART00000058745
zgc:165461
zgc:165461
chr11_-_25213651 0.18 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr20_-_23472319 0.17 ENSDART00000123222
slain2
SLAIN motif family, member 2
chr12_+_7491690 0.17 ENSDART00000152564
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr18_+_17493859 0.17 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr11_-_44543082 0.17 ENSDART00000099568
gpr137bb
G protein-coupled receptor 137Bb
chr15_-_33896159 0.17 ENSDART00000159791
mag
myelin associated glycoprotein
chr1_-_59176949 0.17 ENSDART00000128742
CABZ01118678.1

chr2_+_6181383 0.16 ENSDART00000153307
si:ch73-344o19.1
si:ch73-344o19.1
chr3_+_7808459 0.16 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr10_+_22782522 0.16 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr22_-_24757785 0.16 ENSDART00000078225
vtg5
vitellogenin 5
chr3_+_13440900 0.16 ENSDART00000143715
GNG14
si:dkey-117i10.1
chr25_+_10830269 0.16 ENSDART00000175736
si:ch211-147g22.5
si:ch211-147g22.5
chr23_-_3703569 0.15 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr1_+_57311901 0.15 ENSDART00000149397
mycbpap
mycbp associated protein
chr8_-_2434282 0.15 ENSDART00000137262
ENSDART00000134044
vdac3
voltage-dependent anion channel 3
chr3_+_29600917 0.15 ENSDART00000048867
sstr3
somatostatin receptor 3
chr3_-_18710009 0.15 ENSDART00000142478
grid2ipa
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr14_-_42997145 0.15 ENSDART00000172801
pcdh10b
protocadherin 10b
chr4_+_75314247 0.15 ENSDART00000162365
CABZ01041913.1

chr21_+_35327589 0.15 ENSDART00000145191
ENSDART00000132743
rars
arginyl-tRNA synthetase
chr14_+_28438947 0.14 ENSDART00000006489
acsl4a
acyl-CoA synthetase long chain family member 4a
chr1_-_16507812 0.14 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr1_+_16127825 0.14 ENSDART00000122503
tusc3
tumor suppressor candidate 3
chr15_+_9297340 0.14 ENSDART00000055554
slc37a4a
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr5_+_15350954 0.14 ENSDART00000140990
ENSDART00000137287
ENSDART00000061653
pebp1
phosphatidylethanolamine binding protein 1
chr3_+_17547532 0.14 ENSDART00000175485
ENSDART00000153763
kcnh4a
potassium voltage-gated channel, subfamily H (eag-related), member 4a
chr5_-_29643381 0.14 ENSDART00000034849
grin1b
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr8_-_7391721 0.14 ENSDART00000149836
lhfpl4b
LHFPL tetraspan subfamily member 4b
chr7_-_30082931 0.13 ENSDART00000075600
tspan3b
tetraspanin 3b
chr1_-_38813679 0.13 ENSDART00000148917
asb5b
ankyrin repeat and SOCS box containing 5b
chr23_+_44634187 0.13 ENSDART00000143688
si:ch73-265d7.2
si:ch73-265d7.2
chr16_-_13612650 0.13 ENSDART00000080372
dbpb
D site albumin promoter binding protein b
chr6_-_60031693 0.13 ENSDART00000160275
CABZ01079262.1

chr24_+_26036395 0.13 ENSDART00000143485
tnk2a
tyrosine kinase, non-receptor, 2a
chr23_-_11870962 0.13 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr20_-_29864390 0.13 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr24_+_42004640 0.13 ENSDART00000171380
top1mt
DNA topoisomerase I mitochondrial
chr16_+_5678071 0.13 ENSDART00000011166
ENSDART00000134198
ENSDART00000131575
zgc:158689
zgc:158689
chr18_-_26785861 0.13 ENSDART00000098361
nmba
neuromedin Ba
chr25_-_5740334 0.13 ENSDART00000169622
ENSDART00000168720
LO017739.1

chr9_-_202805 0.13 ENSDART00000182260
CABZ01067557.1

chr1_-_31505144 0.12 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr3_+_12710350 0.12 ENSDART00000157959
cyp2k18
cytochrome P450, family 2, subfamily K, polypeptide 18
chr4_+_26496489 0.12 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
chr18_-_26675699 0.12 ENSDART00000113280
FRMD5
si:ch211-69m14.1
chr13_+_22249636 0.12 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr4_-_75047192 0.12 ENSDART00000193576
large1
LARGE xylosyl- and glucuronyltransferase 1
chr18_-_15373620 0.12 ENSDART00000031752
rfx4
regulatory factor X, 4
chr11_+_6819050 0.12 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr19_+_1184878 0.12 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr9_+_32428679 0.12 ENSDART00000187650
ENSDART00000190472
plcl1
phospholipase C like 1
chr24_-_37698796 0.12 ENSDART00000172178
si:ch211-231f6.6
si:ch211-231f6.6
chr10_+_7563755 0.12 ENSDART00000165877
purg
purine-rich element binding protein G
chr24_+_39137001 0.12 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr23_+_6232895 0.12 ENSDART00000139795
syt2a
synaptotagmin IIa
chr6_+_41463786 0.12 ENSDART00000065006
twf2a
twinfilin actin-binding protein 2a
chr2_+_29610114 0.12 ENSDART00000131271
dlgap1a
discs, large (Drosophila) homolog-associated protein 1a
chr16_-_2818170 0.11 ENSDART00000081918
acot22
acyl-CoA thioesterase 22
chr22_-_18022416 0.11 ENSDART00000141563
ncanb
neurocan b
chr19_-_47456787 0.11 ENSDART00000168792
tfap2e
transcription factor AP-2 epsilon
chr6_+_1787160 0.11 ENSDART00000113505
myl9b
myosin, light chain 9b, regulatory
chr16_-_5844881 0.11 ENSDART00000085678
trak1a
trafficking protein, kinesin binding 1a
chr7_-_72435159 0.11 ENSDART00000173060
rph3ab
rabphilin 3A homolog (mouse), b
chr2_-_34483597 0.11 ENSDART00000133224
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr25_-_15214161 0.11 ENSDART00000031499
wt1a
wilms tumor 1a
chr21_-_22812417 0.11 ENSDART00000079151
ENSDART00000112175
trpc6a
transient receptor potential cation channel, subfamily C, member 6a
chr10_+_7564106 0.10 ENSDART00000159042
purg
purine-rich element binding protein G
chr12_+_27068525 0.10 ENSDART00000188634
srcap
Snf2-related CREBBP activator protein
chr1_+_54673846 0.10 ENSDART00000145018
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb
chr6_-_1566581 0.10 ENSDART00000192993
trim107
tripartite motif containing 107
chr23_+_45822935 0.10 ENSDART00000161892
vdra
vitamin D receptor a
chr25_+_27937585 0.10 ENSDART00000151994
cadps2
Ca++-dependent secretion activator 2
chr17_-_37474689 0.10 ENSDART00000103980
crip2
cysteine-rich protein 2
chr23_+_26026383 0.10 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr9_-_22892838 0.10 ENSDART00000143888
neb
nebulin
chr6_-_29305132 0.10 ENSDART00000132456
bivm
basic, immunoglobulin-like variable motif containing
chr20_+_39457598 0.10 ENSDART00000140931
ENSDART00000156176
pimr128
Pim proto-oncogene, serine/threonine kinase, related 128
chr13_+_23677949 0.10 ENSDART00000144215
pcnxl2
pecanex-like 2 (Drosophila)
chr19_+_30662529 0.10 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr4_-_2162688 0.10 ENSDART00000148900
kcnc2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr19_-_42045372 0.09 ENSDART00000144275
trioa
trio Rho guanine nucleotide exchange factor a
chr6_-_6254432 0.09 ENSDART00000081952
rtn4a
reticulon 4a
chr16_-_44649053 0.09 ENSDART00000184807
CR925804.2

chr7_-_19369002 0.09 ENSDART00000165680
ntn4
netrin 4
chr9_-_49493305 0.09 ENSDART00000148707
ENSDART00000148561
xirp2b
xin actin binding repeat containing 2b
chr12_+_27589607 0.09 ENSDART00000066288
spata20
spermatogenesis associated 20
chr14_+_39255437 0.09 ENSDART00000147443
diaph2
diaphanous-related formin 2
chr14_+_36231126 0.09 ENSDART00000141766
elovl6
ELOVL fatty acid elongase 6
chr6_-_1566407 0.09 ENSDART00000112118
trim107
tripartite motif containing 107
chr13_-_31878263 0.09 ENSDART00000180411
syt14a
synaptotagmin XIVa
chr1_+_2112726 0.09 ENSDART00000131714
ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr25_-_19420949 0.09 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr6_-_9563534 0.09 ENSDART00000184765
map3k2
mitogen-activated protein kinase kinase kinase 2
chr8_+_25913787 0.09 ENSDART00000190257
ENSDART00000062515
sema3h
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H
chr17_+_9040165 0.09 ENSDART00000181221
ENSDART00000181846
akap6
A kinase (PRKA) anchor protein 6
chr11_+_30960743 0.09 ENSDART00000149597
cacna1ab
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr4_-_25271455 0.09 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr16_+_22618620 0.09 ENSDART00000185728
ENSDART00000041625
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr3_-_31226841 0.09 ENSDART00000085903
syt17
synaptotagmin XVII
chr6_+_475264 0.09 ENSDART00000193615
LO017974.1

chr7_+_31871830 0.09 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr20_-_23426339 0.09 ENSDART00000004625
zar1
zygote arrest 1
chr15_-_35406564 0.08 ENSDART00000086051
mecom
MDS1 and EVI1 complex locus
chr11_+_42585138 0.08 ENSDART00000019008
asb14a
ankyrin repeat and SOCS box containing 14a
chr6_+_29305190 0.08 ENSDART00000078647
si:ch211-201h21.5
si:ch211-201h21.5
chr4_-_1360495 0.08 ENSDART00000164623
ptn
pleiotrophin
chr8_+_29749017 0.08 ENSDART00000185144
mapk4
mitogen-activated protein kinase 4
chr15_+_47386939 0.08 ENSDART00000128224
FO904873.1

chr12_-_37653685 0.08 ENSDART00000085121
sdk2b
sidekick cell adhesion molecule 2b
chr17_-_2386569 0.08 ENSDART00000121614
PLCB2
phospholipase C beta 2
chr11_-_6001845 0.08 ENSDART00000108628
ano8b
anoctamin 8b
chr22_-_34995333 0.08 ENSDART00000110900
kcnip2
Kv channel interacting protein 2
chr10_+_22775253 0.08 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr21_+_22738939 0.08 ENSDART00000151342
ENSDART00000079145
arhgap42a
Rho GTPase activating protein 42a
chr18_+_36782930 0.08 ENSDART00000004129
si:ch211-160d20.3
si:ch211-160d20.3
chr2_-_58142854 0.08 ENSDART00000169909
CABZ01110881.1

chr25_+_22730490 0.08 ENSDART00000149455
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr25_+_459901 0.08 ENSDART00000154895
prtgb
protogenin homolog b (Gallus gallus)
chr18_+_26750516 0.08 ENSDART00000110843
alpk3a
alpha-kinase 3a
chr16_-_27149202 0.08 ENSDART00000179726
tmem245
transmembrane protein 245
chr10_-_39153959 0.08 ENSDART00000150193
ENSDART00000111362
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr13_-_39947335 0.08 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr2_-_4797512 0.08 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr9_-_31524907 0.08 ENSDART00000142904
ENSDART00000127214
ENSDART00000133427
ENSDART00000146268
ENSDART00000182541
ENSDART00000184736
tmtc4
transmembrane and tetratricopeptide repeat containing 4
chr12_-_35582683 0.08 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr17_-_36529016 0.08 ENSDART00000025019
colec11
collectin sub-family member 11
chr21_-_10446405 0.07 ENSDART00000167948
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr1_+_39553040 0.07 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr21_+_39185761 0.07 ENSDART00000075992
ENSDART00000140644
cryba1b
crystallin, beta A1b
chr13_+_51869025 0.07 ENSDART00000187066
LT631684.1

chr9_+_38168012 0.07 ENSDART00000102445
clasp1a
cytoplasmic linker associated protein 1a
chr25_-_29134654 0.07 ENSDART00000067066
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr13_-_29424454 0.07 ENSDART00000026765
slc18a3a
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr11_+_42587900 0.07 ENSDART00000167529
asb14a
ankyrin repeat and SOCS box containing 14a
chr8_+_36339470 0.07 ENSDART00000191250
FO744840.1

chr21_+_26612777 0.07 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr9_+_21281652 0.07 ENSDART00000113352
lats2
large tumor suppressor kinase 2
chr13_-_31878043 0.07 ENSDART00000187720
syt14a
synaptotagmin XIVa
chr13_+_8677166 0.07 ENSDART00000181016
ENSDART00000135028
prop1
PROP paired-like homeobox 1
chr18_-_37007061 0.07 ENSDART00000136432
map3k10
mitogen-activated protein kinase kinase kinase 10
chr1_-_46343999 0.07 ENSDART00000145117
ENSDART00000193233
atp11a
ATPase phospholipid transporting 11A
chr20_-_34768301 0.07 ENSDART00000142482
paqr8
progestin and adipoQ receptor family member VIII
chr3_+_33745014 0.07 ENSDART00000159966
nacc1a
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a
chr1_-_22512063 0.07 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr14_-_46675850 0.07 ENSDART00000113285
tapt1a
transmembrane anterior posterior transformation 1a
chr14_-_7128980 0.07 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr3_-_40054615 0.07 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr15_+_20352123 0.07 ENSDART00000011030
ENSDART00000163532
ENSDART00000169537
ENSDART00000161047
il15l
interleukin 15, like
chr12_-_30841679 0.07 ENSDART00000105594
crygmx
crystallin, gamma MX
chr19_-_868187 0.07 ENSDART00000186626
eomesa
eomesodermin homolog a
chr8_+_35664152 0.06 ENSDART00000144520
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr8_+_32742650 0.06 ENSDART00000138117
hmcn2
hemicentin 2
chr4_-_14191434 0.06 ENSDART00000142374
ENSDART00000136730
pus7l
pseudouridylate synthase 7-like
chr6_-_29537219 0.06 ENSDART00000180262
pex5la
peroxisomal biogenesis factor 5-like a
chr14_-_8724290 0.06 ENSDART00000161171
pimr56
Pim proto-oncogene, serine/threonine kinase, related 56
chr6_-_13783604 0.06 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
cryba2a
crystallin, beta A2a
chr6_-_33707278 0.06 ENSDART00000188103
mast2
microtubule associated serine/threonine kinase 2
chr19_-_874888 0.06 ENSDART00000007206
eomesa
eomesodermin homolog a
chr1_+_26105141 0.06 ENSDART00000102379
ENSDART00000127154
toporsa
topoisomerase I binding, arginine/serine-rich a
chr18_-_37007294 0.06 ENSDART00000088309
map3k10
mitogen-activated protein kinase kinase kinase 10
chr20_+_54738210 0.06 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr20_-_25669813 0.06 ENSDART00000153118
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr20_+_19793620 0.06 ENSDART00000136317
chrna2b
cholinergic receptor, nicotinic, alpha 2b (neuronal)
chr5_-_67629263 0.06 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr19_+_4912817 0.06 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr24_-_1356668 0.06 ENSDART00000188935
nrp1a
neuropilin 1a
chr6_+_24420523 0.06 ENSDART00000185461
tgfbr3
transforming growth factor, beta receptor III

Network of associatons between targets according to the STRING database.

First level regulatory network of thraa+thrab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042560 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.4 GO:0032570 response to progesterone(GO:0032570)
0.1 0.2 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.2 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.3 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.7 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:1902837 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.1 GO:2000726 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.1 GO:0061032 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.1 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.4 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0061213 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.0 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.0 GO:0042822 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.0 GO:0000256 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.0 0.1 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.0 0.0 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.0 0.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type