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PRJNA207719: Tissue specific transcriptome profiling

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Results for tlx1

Z-value: 1.05

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Transcription factors associated with tlx1

Gene Symbol Gene ID Gene Info
tlx1
ENSDARG00000003965 T cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tlx1dr11_v1_chr13_-_28272299_28272299-0.494.0e-01Click!

Activity profile of tlx1 motif

Sorted Z-values of tlx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_-_4146947 1.12 ENSDART00000129268
fads2
fatty acid desaturase 2
chr12_+_33403694 0.51 ENSDART00000124083
fasn
fatty acid synthase
chr20_+_10545514 0.49 ENSDART00000153667
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr2_-_17827983 0.48 ENSDART00000166518
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr17_-_50233493 0.43 ENSDART00000172266
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr22_+_38229321 0.41 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr20_+_10539293 0.40 ENSDART00000182265
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr8_-_53108207 0.40 ENSDART00000111023
b3galt4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr7_-_51953613 0.39 ENSDART00000142042
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr3_-_5664123 0.35 ENSDART00000145866
si:ch211-106h11.1
si:ch211-106h11.1
chr12_+_13405445 0.33 ENSDART00000089042
kcnh4b
potassium voltage-gated channel, subfamily H (eag-related), member 4b
chr15_-_20745513 0.33 ENSDART00000187438
tpst1
tyrosylprotein sulfotransferase 1
chr7_-_51953807 0.32 ENSDART00000174102
ENSDART00000145645
ENSDART00000052054
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr11_-_34147205 0.32 ENSDART00000173216
atp13a3
ATPase 13A3
chr13_+_37040789 0.32 ENSDART00000063412
esr2b
estrogen receptor 2b
chr7_-_52096498 0.31 ENSDART00000098688
ENSDART00000098690
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr1_+_4101741 0.31 ENSDART00000163793
slitrk6
SLIT and NTRK-like family, member 6
chr17_-_31308658 0.29 ENSDART00000124505
bahd1
bromo adjacent homology domain containing 1
chr6_+_53349966 0.28 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr17_-_22067451 0.27 ENSDART00000156872
ttbk1b
tau tubulin kinase 1b
chr5_+_31283576 0.26 ENSDART00000133743
camkk1a
calcium/calmodulin-dependent protein kinase kinase 1, alpha a
chr7_-_24472991 0.26 ENSDART00000121684
nat8l
N-acetyltransferase 8-like
chr3_+_24482999 0.26 ENSDART00000059179
nptxra
neuronal pentraxin receptor a
chr7_+_14291323 0.25 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr16_+_14029283 0.24 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr8_-_16712111 0.24 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr14_-_25444774 0.24 ENSDART00000183448
slc26a2
solute carrier family 26 (anion exchanger), member 2
chr4_+_74131530 0.24 ENSDART00000174125
CABZ01072523.1

chr18_-_39473055 0.24 ENSDART00000122930
scg3
secretogranin III
chr14_-_32503363 0.23 ENSDART00000034883
mcf2a
MCF.2 cell line derived transforming sequence a
chr11_-_103136 0.23 ENSDART00000173308
ENSDART00000162982
elmo2
engulfment and cell motility 2
chr2_-_7800702 0.23 ENSDART00000146360
tbl1xr1b
transducin (beta)-like 1 X-linked receptor 1b
chr17_-_22048233 0.22 ENSDART00000155203
ttbk1b
tau tubulin kinase 1b
chr21_+_39336285 0.22 ENSDART00000139677
si:ch211-274p24.4
si:ch211-274p24.4
chr4_-_18281070 0.22 ENSDART00000135330
ENSDART00000179075
ENSDART00000046871
uhrf1bp1l
UHRF1 binding protein 1-like
chr17_+_38262408 0.22 ENSDART00000017493
nkx2.1
NK2 homeobox 1
chr11_-_13341051 0.22 ENSDART00000121872
mast3b
microtubule associated serine/threonine kinase 3b
chr19_-_47571797 0.22 ENSDART00000166180
ENSDART00000168134
rrm2
ribonucleotide reductase M2 polypeptide
chr9_-_23358597 0.21 ENSDART00000046423
arl4cb
ADP-ribosylation factor-like 4Cb
chr25_+_2993855 0.20 ENSDART00000163009
neo1b
neogenin 1b
chr24_+_25692802 0.20 ENSDART00000190493
camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr5_+_28398449 0.20 ENSDART00000165292
nsmfb
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr11_-_13341483 0.20 ENSDART00000164978
mast3b
microtubule associated serine/threonine kinase 3b
chr10_-_7857494 0.20 ENSDART00000143215
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr1_-_56363108 0.19 ENSDART00000021878
gcgrb
glucagon receptor b
chr17_+_52822422 0.19 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr25_-_31118923 0.18 ENSDART00000009126
ENSDART00000188286
kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr12_+_35654749 0.18 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr3_-_15081874 0.18 ENSDART00000192532
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr11_+_38332419 0.18 ENSDART00000005864
CDK18
si:dkey-166c18.1
chr23_-_45504991 0.18 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr6_+_2951645 0.18 ENSDART00000183181
ENSDART00000181271
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr4_-_4250317 0.17 ENSDART00000103316
cd9b
CD9 molecule b
chr20_+_16750177 0.17 ENSDART00000185357
calm1b
calmodulin 1b
chr7_+_47316944 0.17 ENSDART00000173534
dpy19l3
dpy-19 like C-mannosyltransferase 3
chr3_-_33574576 0.17 ENSDART00000184881
CR847537.1

chr20_-_29499363 0.17 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr10_-_17232372 0.17 ENSDART00000135679
rab36
RAB36, member RAS oncogene family
chr13_-_9895564 0.16 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
si:ch211-117n7.6
chr13_+_18371208 0.16 ENSDART00000138172
ccar1
cell division cycle and apoptosis regulator 1
chr23_-_38497705 0.16 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr4_-_38033800 0.16 ENSDART00000159662
si:dkeyp-82b4.4
si:dkeyp-82b4.4
chr21_-_22681534 0.16 ENSDART00000159233
gig2f
grass carp reovirus (GCRV)-induced gene 2f
chr13_-_31829786 0.16 ENSDART00000138667
sertad4
SERTA domain containing 4
chr19_+_21818460 0.15 ENSDART00000189427
ENSDART00000180525
CU856623.1

chr3_-_3439150 0.15 ENSDART00000021286
A2ML1 (1 of many)
si:dkey-46g23.5
chr19_+_22727940 0.15 ENSDART00000052509
trhrb
thyrotropin-releasing hormone receptor b
chr7_-_22132265 0.15 ENSDART00000125284
ENSDART00000112978
nlgn2a
neuroligin 2a
chr5_-_67629263 0.14 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr17_+_37645633 0.14 ENSDART00000085500
tmem229b
transmembrane protein 229B
chr8_+_9699111 0.14 ENSDART00000111853
gripap1
GRIP1 associated protein 1
chr4_+_61171310 0.14 ENSDART00000141738
si:dkey-9p20.18
si:dkey-9p20.18
chr22_-_22416337 0.14 ENSDART00000142947
ENSDART00000089569
camsap2a
calmodulin regulated spectrin-associated protein family, member 2a
chr14_+_16036139 0.14 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr25_-_30394746 0.13 ENSDART00000185346
si:ch211-93f2.1
si:ch211-93f2.1
chr18_-_2433011 0.13 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr15_-_14469704 0.13 ENSDART00000185077
numbl
numb homolog (Drosophila)-like
chr8_+_44722140 0.13 ENSDART00000163381
elmod3
ELMO/CED-12 domain containing 3
chr1_-_58059134 0.13 ENSDART00000160970
caspb
caspase b
chr8_+_44623540 0.13 ENSDART00000141513
grk5l
G protein-coupled receptor kinase 5 like
chr8_+_53423408 0.13 ENSDART00000164792
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr6_-_21873266 0.13 ENSDART00000151658
ENSDART00000151152
ENSDART00000151179
si:dkey-19e4.5
si:dkey-19e4.5
chr1_-_22757145 0.13 ENSDART00000134719
prom1b
prominin 1 b
chr7_+_52135791 0.13 ENSDART00000098705
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr15_+_22722684 0.12 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr8_+_1284784 0.12 ENSDART00000061663
fbxl17
F-box and leucine-rich repeat protein 17
chr16_-_22585289 0.12 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr6_-_39199070 0.12 ENSDART00000131793
c1galt1b
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr7_+_23292133 0.12 ENSDART00000134489
htr2cl1
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1
chr9_+_16449398 0.12 ENSDART00000006787
epha3
eph receptor A3
chr1_+_49568335 0.12 ENSDART00000142957
col17a1a
collagen, type XVII, alpha 1a
chr20_+_54383838 0.12 ENSDART00000157737
lrfn5b
leucine rich repeat and fibronectin type III domain containing 5b
chr6_+_39184236 0.11 ENSDART00000156187
tac3b
tachykinin 3b
chr15_+_23528010 0.11 ENSDART00000152786
si:dkey-182i3.8
si:dkey-182i3.8
chr8_-_34052019 0.11 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr19_+_40379771 0.11 ENSDART00000017917
ENSDART00000110699
vps50
vps50
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr15_-_18091157 0.11 ENSDART00000153848
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr17_+_10578823 0.11 ENSDART00000134610
mgaa
MGA, MAX dimerization protein a
chr18_+_7543347 0.11 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr1_-_33645967 0.11 ENSDART00000192758
cldng
claudin g
chr23_-_18572521 0.11 ENSDART00000138599
ssr4
signal sequence receptor, delta
chr20_-_3390406 0.11 ENSDART00000136987
rev3l
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr23_-_18572685 0.11 ENSDART00000047175
ssr4
signal sequence receptor, delta
chr4_-_64709908 0.10 ENSDART00000161032
si:dkey-9i5.2
si:dkey-9i5.2
chr8_-_31053872 0.10 ENSDART00000109885
snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr2_-_37352514 0.10 ENSDART00000140498
ENSDART00000186422
skila
SKI-like proto-oncogene a
chr3_+_40407352 0.10 ENSDART00000155112
tnrc18
trinucleotide repeat containing 18
chr20_+_25581627 0.09 ENSDART00000030229
cyp2p9
cytochrome P450, family 2, subfamily P, polypeptide 9
chr20_+_34320635 0.09 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr10_-_29827000 0.09 ENSDART00000131418
zpr1
ZPR1 zinc finger
chr2_-_8017579 0.09 ENSDART00000040209
ephb3a
eph receptor B3a
chr3_-_34599662 0.09 ENSDART00000055259
nmrk1
nicotinamide riboside kinase 1
chr2_+_50722439 0.09 ENSDART00000188927
fyco1b
FYVE and coiled-coil domain containing 1b
chr15_-_38202630 0.09 ENSDART00000183772
rhoga
ras homolog family member Ga
chr1_-_22756898 0.08 ENSDART00000158915
prom1b
prominin 1 b
chr23_-_14057191 0.08 ENSDART00000154908
adcy6a
adenylate cyclase 6a
chr3_+_57038033 0.08 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr2_+_37207461 0.08 ENSDART00000138952
ENSDART00000132856
ENSDART00000137272
ENSDART00000143468
apoda.2
apolipoprotein Da, duplicate 2
chr18_+_41560822 0.08 ENSDART00000158503
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr8_-_39822917 0.08 ENSDART00000067843
zgc:162025
zgc:162025
chr25_-_17378881 0.07 ENSDART00000064586
cyp2x7
cytochrome P450, family 2, subfamily X, polypeptide 7
chr18_+_40462445 0.07 ENSDART00000087645
ugt5c2
UDP glucuronosyltransferase 5 family, polypeptide C2
chr14_-_41388178 0.07 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr22_+_39058269 0.07 ENSDART00000113362
ip6k1
inositol hexakisphosphate kinase 1
chr22_+_11857356 0.07 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr13_-_41482064 0.07 ENSDART00000188322
ENSDART00000164732
pcdh15a
protocadherin-related 15a
chr1_+_35194454 0.07 ENSDART00000165389
sc:d189
sc:d189
chr2_+_30969029 0.07 ENSDART00000085242
lpin2
lipin 2
chr20_-_53949798 0.07 ENSDART00000153435
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr7_+_52122224 0.06 ENSDART00000174268
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr24_-_27409599 0.06 ENSDART00000041770
ccl34b.3
chemokine (C-C motif) ligand 34b, duplicate 3
chr14_+_21820034 0.06 ENSDART00000122739
ctbp1
C-terminal binding protein 1
chr24_+_17262879 0.06 ENSDART00000145949
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr6_+_41957280 0.05 ENSDART00000050114
oxtr
oxytocin receptor
chr13_+_28761998 0.05 ENSDART00000146581
prom2
prominin 2
chr19_-_8926575 0.05 ENSDART00000080897
rprd2a
regulation of nuclear pre-mRNA domain containing 2a
chr20_+_48739154 0.05 ENSDART00000100262
zgc:110348
zgc:110348
chr8_-_1266181 0.05 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr17_-_45040813 0.05 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr13_-_32577386 0.05 ENSDART00000016535
kcns3a
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a
chr24_-_21903360 0.05 ENSDART00000091252
spata13
spermatogenesis associated 13
chr1_-_28629471 0.04 ENSDART00000121758
ednrba
endothelin receptor Ba
chr2_+_29257942 0.04 ENSDART00000184362
ENSDART00000025562
cdh18a
cadherin 18, type 2a
chr3_-_40528333 0.04 ENSDART00000193047
actb2
actin, beta 2
chr5_+_35502290 0.04 ENSDART00000191222
CR762390.1

chr16_-_9453591 0.04 ENSDART00000126154
prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr23_+_21278948 0.04 ENSDART00000156701
ENSDART00000033970
ubr4
ubiquitin protein ligase E3 component n-recognin 4
chr4_-_14531687 0.04 ENSDART00000182093
ENSDART00000159447
plxnb2a
plexin b2a
chr2_-_1364678 0.04 ENSDART00000011919
ENSDART00000164674
ss18
synovial sarcoma translocation, chromosome 18 (H. sapiens)
chr14_+_31865099 0.04 ENSDART00000189124
tm9sf5
transmembrane 9 superfamily protein member 5
chr14_+_31865324 0.03 ENSDART00000039880
tm9sf5
transmembrane 9 superfamily protein member 5
chr20_+_2134816 0.03 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr9_-_44939104 0.03 ENSDART00000192903
vil1
villin 1
chr5_-_57526807 0.02 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr8_-_20118549 0.02 ENSDART00000132218
rfx2
regulatory factor X, 2 (influences HLA class II expression)
chr5_+_63329608 0.02 ENSDART00000139180
si:ch73-376l24.3
si:ch73-376l24.3
chr11_+_37265692 0.02 ENSDART00000184691
il17rc
interleukin 17 receptor C
chr22_-_16400484 0.02 ENSDART00000135987
lama3
laminin, alpha 3
chr10_+_573667 0.01 ENSDART00000110384
smad4a
SMAD family member 4a
chr20_-_2134620 0.01 ENSDART00000064375
tmem244
transmembrane protein 244
chr16_-_11928774 0.01 ENSDART00000183229
cd4-1
CD4-1 molecule
chr4_-_46648979 0.00 ENSDART00000162101
BX927193.2

chr17_-_29771639 0.00 ENSDART00000086201
ush2a
Usher syndrome 2A (autosomal recessive, mild)
chr24_-_20369604 0.00 ENSDART00000143174
dlec1
deleted in lung and esophageal cancer 1
chr2_-_21167652 0.00 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr23_-_6765653 0.00 ENSDART00000192310
FP102169.1

chr5_+_22791686 0.00 ENSDART00000014806
npas2
neuronal PAS domain protein 2
chr21_+_5257018 0.00 ENSDART00000183100
ENSDART00000191525
loxhd1a
lipoxygenase homology domains 1a
chr3_+_61391636 0.00 ENSDART00000126417
bri3
brain protein I3
chr24_-_20369760 0.00 ENSDART00000185585
dlec1
deleted in lung and esophageal cancer 1

Network of associatons between targets according to the STRING database.

First level regulatory network of tlx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.2 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 0.2 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 1.4 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.1 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0044706 parturition(GO:0007567) neurohypophysis development(GO:0021985) multi-multicellular organism process(GO:0044706) maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0042493 response to drug(GO:0042493)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0030667 secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:1903924 estradiol binding(GO:1903924)
0.0 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 1.4 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+