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PRJNA207719: Tissue specific transcriptome profiling

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Results for xbp1

Z-value: 1.11

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Transcription factors associated with xbp1

Gene Symbol Gene ID Gene Info
xbp1
ENSDARG00000035622 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
xbp1dr11_v1_chr5_-_15948833_159489200.838.3e-02Click!

Activity profile of xbp1 motif

Sorted Z-values of xbp1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23984755 0.65 ENSDART00000145328
apoc2
apolipoprotein C-II
chr4_+_68562464 0.60 ENSDART00000192954
BX548011.4

chr16_+_27224369 0.60 ENSDART00000136980
sec61b
Sec61 translocon beta subunit
chr16_+_23984179 0.44 ENSDART00000175879
apoc2
apolipoprotein C-II
chr7_+_10610791 0.43 ENSDART00000166064
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr3_-_25377163 0.42 ENSDART00000055490
kpna2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr16_-_46660680 0.42 ENSDART00000159209
ENSDART00000191929
tmem176l.4
transmembrane protein 176l.4
chr12_-_990149 0.37 ENSDART00000054367
kdelr2b
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr21_+_10701834 0.33 ENSDART00000192473
lman1
lectin, mannose-binding, 1
chr6_+_13506841 0.32 ENSDART00000032331
gmppab
GDP-mannose pyrophosphorylase Ab
chr8_+_11471350 0.32 ENSDART00000092355
ENSDART00000136184
tjp2b
tight junction protein 2b (zona occludens 2)
chr21_+_10702031 0.31 ENSDART00000102304
lman1
lectin, mannose-binding, 1
chr22_-_817479 0.31 ENSDART00000123487
zgc:153675
zgc:153675
chr24_+_14214831 0.30 ENSDART00000004664
tram1
translocation associated membrane protein 1
chr7_-_19614916 0.30 ENSDART00000169029
zgc:194655
zgc:194655
chr16_-_26676685 0.30 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr22_+_38194151 0.29 ENSDART00000121965
cp
ceruloplasmin
chr4_-_13613148 0.29 ENSDART00000067164
ENSDART00000111247
irf5
interferon regulatory factor 5
chr1_-_23308225 0.28 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr25_+_5983430 0.28 ENSDART00000074814
ppib
peptidylprolyl isomerase B (cyclophilin B)
chr19_-_30404096 0.28 ENSDART00000103475
agr2
anterior gradient 2
chr8_-_14554785 0.28 ENSDART00000057645
qsox1
quiescin Q6 sulfhydryl oxidase 1
chr19_-_11238620 0.27 ENSDART00000148697
ENSDART00000149169
ssr2
signal sequence receptor, beta
chr19_-_30403922 0.27 ENSDART00000181841
agr2
anterior gradient 2
chr23_-_18572521 0.27 ENSDART00000138599
ssr4
signal sequence receptor, delta
chr8_+_5024468 0.25 ENSDART00000030938
adra1aa
adrenoceptor alpha 1Aa
chr16_+_35918463 0.24 ENSDART00000160608
sh3d21
SH3 domain containing 21
chr23_-_18572685 0.24 ENSDART00000047175
ssr4
signal sequence receptor, delta
chr6_+_6779114 0.24 ENSDART00000163493
ENSDART00000143359
sec23b
Sec23 homolog B, COPII coat complex component
chr7_+_19615056 0.24 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
si:ch211-212k18.15
chr24_-_42090635 0.24 ENSDART00000166413
ssr1
signal sequence receptor, alpha
chr18_+_7553950 0.24 ENSDART00000193420
ENSDART00000062143
zgc:77650
zgc:77650
chr17_+_32360673 0.24 ENSDART00000155519
si:ch211-139d20.3
si:ch211-139d20.3
chr5_+_58550291 0.23 ENSDART00000184983
ENSDART00000044803
pou2f3
POU class 2 homeobox 3
chr10_-_34915886 0.23 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr25_+_3759553 0.23 ENSDART00000180601
ENSDART00000055845
ENSDART00000157050
ENSDART00000153905
thoc5
THO complex 5
chr10_-_22150419 0.22 ENSDART00000006173
cldn7b
claudin 7b
chr19_+_18903533 0.22 ENSDART00000157523
ENSDART00000166562
slc39a7
solute carrier family 39 (zinc transporter), member 7
chr17_+_53156530 0.22 ENSDART00000126277
ENSDART00000156774
dph6
diphthamine biosynthesis 6
chr1_-_45049603 0.22 ENSDART00000023336
rps6
ribosomal protein S6
chr24_-_33291784 0.22 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr5_+_69868911 0.21 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr11_+_44503774 0.21 ENSDART00000169295
ero1b
endoplasmic reticulum oxidoreductase beta
chr13_-_47403154 0.21 ENSDART00000114318
bcl2l11
BCL2 like 11
chr11_-_7261717 0.21 ENSDART00000128959
zgc:113223
zgc:113223
chr5_+_65087226 0.20 ENSDART00000183187
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr7_+_44715224 0.20 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr21_-_22693730 0.20 ENSDART00000158342
gig2d
grass carp reovirus (GCRV)-induced gene 2d
chr6_-_40071899 0.20 ENSDART00000034730
sec61a1
Sec61 translocon alpha 1 subunit
chr25_-_37262220 0.20 ENSDART00000153789
ENSDART00000155182
rfwd3
ring finger and WD repeat domain 3
chr17_+_24446705 0.19 ENSDART00000163221
ugp2b
UDP-glucose pyrophosphorylase 2b
chr10_-_44305180 0.19 ENSDART00000187552
CDK2AP1
cyclin dependent kinase 2 associated protein 1
chr23_+_43638982 0.18 ENSDART00000168646
slc10a7
solute carrier family 10, member 7
chr22_-_10152629 0.18 ENSDART00000144209
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr5_+_65086856 0.18 ENSDART00000169209
ENSDART00000162409
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr2_-_42492201 0.17 ENSDART00000180762
ENSDART00000009093
esyt2a
extended synaptotagmin-like protein 2a
chr4_+_77957611 0.17 ENSDART00000156692
arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr5_+_2002804 0.17 ENSDART00000064088
vkorc1l1
vitamin K epoxide reductase complex, subunit 1-like 1
chr18_-_34170918 0.17 ENSDART00000015079
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr22_+_31059919 0.17 ENSDART00000077063
sec13
SEC13 homolog, nuclear pore and COPII coat complex component
chr5_+_65086668 0.16 ENSDART00000183746
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr4_-_19693978 0.16 ENSDART00000100974
ENSDART00000040405
snd1
staphylococcal nuclease and tudor domain containing 1
chr1_-_9486214 0.16 ENSDART00000137821
micall2b
mical-like 2b
chr2_+_36608387 0.16 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr2_-_55298075 0.16 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr12_-_16452200 0.16 ENSDART00000037601
rpp30
ribonuclease P/MRP 30 subunit
chr20_-_26929685 0.15 ENSDART00000132556
ftr79
finTRIM family, member 79
chr19_+_43119698 0.15 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr14_-_45464112 0.15 ENSDART00000173209
ehd1a
EH-domain containing 1a
chr10_+_16165533 0.15 ENSDART00000065045
prrc1
proline-rich coiled-coil 1
chr4_-_17725008 0.15 ENSDART00000016658
chpt1
choline phosphotransferase 1
chr24_-_26485098 0.15 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr22_-_17781213 0.14 ENSDART00000137984
si:ch73-63e15.2
si:ch73-63e15.2
chr3_+_28860283 0.14 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr10_+_39212898 0.14 ENSDART00000159501
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr2_-_9527129 0.14 ENSDART00000157422
ENSDART00000004398
cope
coatomer protein complex, subunit epsilon
chr6_-_54816567 0.14 ENSDART00000150079
tnni1b
troponin I type 1b (skeletal, slow)
chr18_-_34171280 0.14 ENSDART00000122321
slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr9_+_25840720 0.14 ENSDART00000024572
gtdc1
glycosyltransferase-like domain containing 1
chr20_-_30377221 0.14 ENSDART00000126229
rps7
ribosomal protein S7
chr6_-_42388608 0.14 ENSDART00000049425
sec61a1l
Sec61 translocon alpha 1 subunit, like
chr19_+_1414604 0.14 ENSDART00000159024
btr29
bloodthirsty-related gene family, member 29
chr4_-_5912951 0.14 ENSDART00000169439
arl1
ADP-ribosylation factor-like 1
chr16_-_5115993 0.14 ENSDART00000138654
ttk
ttk protein kinase
chr1_+_52754085 0.14 ENSDART00000185420
wu:fc75a09
wu:fc75a09
chr11_+_45286911 0.14 ENSDART00000181763
pycr1b
pyrroline-5-carboxylate reductase 1b
chr11_-_2700397 0.14 ENSDART00000082511
si:ch211-160o17.6
si:ch211-160o17.6
chr12_+_30788912 0.14 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr12_+_30789611 0.13 ENSDART00000181501
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr9_-_2594410 0.13 ENSDART00000188306
ENSDART00000164276
sp9
sp9 transcription factor
chr4_+_25651720 0.13 ENSDART00000100693
ENSDART00000100717
acot16
acyl-CoA thioesterase 16
chr23_-_24493768 0.13 ENSDART00000135559
ENSDART00000046933
sult1st5
sulfotransferase family 1, cytosolic sulfotransferase 5
chr11_+_6431133 0.13 ENSDART00000190742
FO904935.1

chr11_-_6420917 0.13 ENSDART00000193717
FO681393.2

chr19_+_14113886 0.12 ENSDART00000169343
kdf1b
keratinocyte differentiation factor 1b
chr25_-_774350 0.12 ENSDART00000166321
ENSDART00000160386
IRAK4
interleukin 1 receptor associated kinase 4
chr6_-_35052145 0.12 ENSDART00000073970
ENSDART00000185790
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr1_+_38142354 0.12 ENSDART00000179352
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr9_-_27748868 0.12 ENSDART00000190306
tbccd1
TBCC domain containing 1
chr20_-_40758410 0.12 ENSDART00000183031
cx34.5
connexin 34.5
chr2_-_7757273 0.12 ENSDART00000136074
b3gnt5b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5b
chr12_-_4206869 0.12 ENSDART00000106572
si:dkey-32n7.9
si:dkey-32n7.9
chr4_-_77979432 0.11 ENSDART00000049170
zgc:85975
zgc:85975
chr17_+_24446353 0.11 ENSDART00000140467
ugp2b
UDP-glucose pyrophosphorylase 2b
chr5_+_24543862 0.11 ENSDART00000029699
atp6v0a2b
ATPase H+ transporting V0 subunit a2b
chr1_-_9485939 0.11 ENSDART00000157814
micall2b
mical-like 2b
chr24_-_982443 0.11 ENSDART00000063151
napga
N-ethylmaleimide-sensitive factor attachment protein, gamma a
chr2_-_22363460 0.11 ENSDART00000158486
selenof
selenoprotein F
chr5_+_21211135 0.11 ENSDART00000088492
bmp10
bone morphogenetic protein 10
chr11_+_45287541 0.11 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr5_-_41841675 0.11 ENSDART00000141683
si:dkey-65b12.6
si:dkey-65b12.6
chr12_+_31783066 0.11 ENSDART00000105584
lrrc59
leucine rich repeat containing 59
chr9_+_54237100 0.10 ENSDART00000148928
rbm27
RNA binding motif protein 27
chr17_+_24446533 0.10 ENSDART00000131417
ugp2b
UDP-glucose pyrophosphorylase 2b
chr14_-_16082806 0.10 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr6_-_52348562 0.10 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eif6
eukaryotic translation initiation factor 6
chr22_+_3238474 0.10 ENSDART00000157954
si:ch1073-178p5.3
si:ch1073-178p5.3
chr4_+_13568469 0.10 ENSDART00000171235
ENSDART00000136152
calua
calumenin a
chr7_-_56606752 0.10 ENSDART00000138714
sult5a1
sulfotransferase family 5A, member 1
chr24_-_11069237 0.10 ENSDART00000127398
CR753886.1

chr25_-_3034668 0.10 ENSDART00000053405
scamp2
secretory carrier membrane protein 2
chr18_-_18587745 0.09 ENSDART00000191973
sf3b3
splicing factor 3b, subunit 3
chr10_+_39212601 0.09 ENSDART00000168778
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr5_+_20453874 0.09 ENSDART00000124545
ENSDART00000008402
sart3
squamous cell carcinoma antigen recognized by T cells 3
chr14_+_31566517 0.09 ENSDART00000002684
ints6l
integrator complex subunit 6 like
chr1_+_38142715 0.09 ENSDART00000079928
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr1_-_53277413 0.09 ENSDART00000150579
znf330
zinc finger protein 330
chr19_-_29832876 0.09 ENSDART00000005119
eif3i
eukaryotic translation initiation factor 3, subunit I
chr19_-_5103141 0.09 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr6_+_3864040 0.09 ENSDART00000013743
gorasp2
golgi reassembly stacking protein 2
chr21_-_8054977 0.08 ENSDART00000130508
si:dkey-163m14.4
si:dkey-163m14.4
chr19_+_26640096 0.08 ENSDART00000067793
ints3
integrator complex subunit 3
chr9_+_20526472 0.08 ENSDART00000166457
ENSDART00000141775
trim45
tripartite motif containing 45
chr6_-_35052388 0.08 ENSDART00000181000
ENSDART00000170116
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr16_+_6727195 0.08 ENSDART00000148625
znf407
zinc finger protein 407
chr6_-_54815886 0.08 ENSDART00000180793
ENSDART00000007498
tnni1b
troponin I type 1b (skeletal, slow)
chr19_-_5103313 0.08 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr12_-_2869565 0.08 ENSDART00000152772
zdhhc16b
zinc finger, DHHC-type containing 16b
chr4_-_5913338 0.08 ENSDART00000183590
arl1
ADP-ribosylation factor-like 1
chr22_+_2844865 0.08 ENSDART00000139123
si:dkey-20i20.4
si:dkey-20i20.4
chr3_-_55092051 0.08 ENSDART00000053077
hbba2
hemoglobin, beta adult 2
chr9_+_38273233 0.08 ENSDART00000142853
clasp1a
cytoplasmic linker associated protein 1a
chr10_-_3427589 0.08 ENSDART00000133452
ENSDART00000037183
tmed2
transmembrane p24 trafficking protein 2
chr8_-_44463985 0.07 ENSDART00000016845
mhc1lba
major histocompatibility complex class I LBA
chr3_-_36209936 0.07 ENSDART00000175208
csnk1da
casein kinase 1, delta a
chr9_+_21165017 0.07 ENSDART00000145933
ENSDART00000142985
si:rp71-68n21.9
si:rp71-68n21.9
chr9_+_23825440 0.07 ENSDART00000138470
ints6
integrator complex subunit 6
chr8_+_47219107 0.07 ENSDART00000146018
ENSDART00000075068
mthfr
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_156375 0.07 ENSDART00000160221
pcid2
PCI domain containing 2
chr25_-_34512102 0.07 ENSDART00000087450
klf13
Kruppel-like factor 13
chr15_-_29326254 0.07 ENSDART00000114492
si:dkey-52l18.4
si:dkey-52l18.4
chr18_+_2593756 0.07 ENSDART00000158022
p2ry2.3
purinergic receptor P2Y2, tandem duplicate 3
chr1_-_26292897 0.07 ENSDART00000112899
ENSDART00000185410
cxxc4
CXXC finger 4
chr22_-_11078988 0.06 ENSDART00000126664
ENSDART00000006927
use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr5_-_56964547 0.06 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr5_+_69278089 0.06 ENSDART00000136656
selenom
selenoprotein M
chr1_+_7956030 0.06 ENSDART00000159655
CR855320.1

chr3_+_29510818 0.06 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
rac2
Rac family small GTPase 2
chr17_-_6765877 0.06 ENSDART00000193102
CR352340.1

chr16_-_42750295 0.06 ENSDART00000176570
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr17_+_24445818 0.06 ENSDART00000139963
ugp2b
UDP-glucose pyrophosphorylase 2b
chr10_-_5857548 0.06 ENSDART00000166933
si:ch211-281k19.2
si:ch211-281k19.2
chr17_+_1514711 0.06 ENSDART00000165641
akt1
v-akt murine thymoma viral oncogene homolog 1
chr1_+_44852497 0.06 ENSDART00000135067
kdm2aa
lysine (K)-specific demethylase 2Aa
chr18_-_7481036 0.06 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr21_+_28724099 0.06 ENSDART00000138017
puraa
purine-rich element binding protein Aa
chr5_+_4366431 0.05 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr5_-_30516646 0.05 ENSDART00000014666
arcn1a
archain 1a
chr2_+_37176814 0.05 ENSDART00000048277
ENSDART00000176827
copa
coatomer protein complex, subunit alpha
chr5_-_24219344 0.05 ENSDART00000011878
eif4a1b
eukaryotic translation initiation factor 4A1B
chr13_-_44808783 0.05 ENSDART00000099984
glo1
glyoxalase 1
chr12_+_1592146 0.05 ENSDART00000184575
ENSDART00000192902
SLC39A11
solute carrier family 39 member 11
chr20_+_29565906 0.05 ENSDART00000062383
ywhaqa
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
chr3_-_34586403 0.05 ENSDART00000151515
sept9a
septin 9a
chr8_-_31701157 0.05 ENSDART00000141799
fbxo4
F-box protein 4
chr3_+_3610140 0.05 ENSDART00000104977
pick1
protein interacting with prkca 1
chr23_+_35672542 0.05 ENSDART00000046268
pmelb
premelanosome protein b
chr19_-_46219035 0.05 ENSDART00000170601
si:ch1073-228h2.2
si:ch1073-228h2.2
chr13_-_38088627 0.05 ENSDART00000175268
CT027676.1

chr6_+_23026714 0.05 ENSDART00000124948
srp68
signal recognition particle 68
chr18_+_6706140 0.05 ENSDART00000111343
lmf2a
lipase maturation factor 2a
chr22_+_1517318 0.05 ENSDART00000160406
si:ch211-255f4.5
si:ch211-255f4.5
chr12_-_35582521 0.05 ENSDART00000162175
ENSDART00000168958
sec24c
SEC24 homolog C, COPII coat complex component
chr1_-_53277187 0.05 ENSDART00000131520
znf330
zinc finger protein 330
chr14_+_1014109 0.05 ENSDART00000157945
f8
coagulation factor VIII, procoagulant component
chr17_+_19630068 0.04 ENSDART00000182619
rgs7a
regulator of G protein signaling 7a
chr10_-_26225548 0.04 ENSDART00000132019
ENSDART00000079194
arfip2b
ADP-ribosylation factor interacting protein 2b
chr7_+_20503344 0.04 ENSDART00000157699
si:dkey-19b23.12
si:dkey-19b23.12
chr23_-_19140781 0.04 ENSDART00000143580
si:ch73-381f5.2
si:ch73-381f5.2
chr11_+_7276824 0.04 ENSDART00000185992
si:ch73-238c9.1
si:ch73-238c9.1
chr6_+_49722970 0.04 ENSDART00000155934
ENSDART00000154738
stx16
syntaxin 16
chr15_-_14193659 0.04 ENSDART00000171197
pnkp
polynucleotide kinase 3'-phosphatase
chr20_+_10723292 0.04 ENSDART00000152805
si:ch211-182e10.4
si:ch211-182e10.4
chr22_-_20386982 0.04 ENSDART00000089015
zbtb7a
zinc finger and BTB domain containing 7a
chr15_-_18115540 0.04 ENSDART00000131639
ENSDART00000047902
arcn1b
archain 1b
chr12_-_35582683 0.04 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr5_+_66220601 0.04 ENSDART00000129903
mfsd10
major facilitator superfamily domain containing 10
chr1_-_44484 0.04 ENSDART00000171547
ENSDART00000164075
ENSDART00000168091
tmem39a
transmembrane protein 39A
chr20_-_438646 0.03 ENSDART00000009196
ufl1
UFM1-specific ligase 1
chr3_-_37588855 0.03 ENSDART00000149258
arf2a
ADP-ribosylation factor 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of xbp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.1 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.2 GO:0051645 Golgi localization(GO:0051645)
0.1 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0060876 semicircular canal formation(GO:0060876)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 1.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687)
0.0 0.2 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.1 GO:0072672 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.1 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 1.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.3 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 0.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.0 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling