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PRJNA207719: Tissue specific transcriptome profiling

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Results for ybx1

Z-value: 0.90

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Transcription factors associated with ybx1

Gene Symbol Gene ID Gene Info
ybx1
ENSDARG00000004757 Y box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ybx1dr11_v1_chr8_-_47152001_47152086-0.167.9e-01Click!

Activity profile of ybx1 motif

Sorted Z-values of ybx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_9830451 0.51 ENSDART00000148528
grhl2a
grainyhead-like transcription factor 2a
chr14_-_246342 0.48 ENSDART00000054823
aurkb
aurora kinase B
chr15_+_46329149 0.43 ENSDART00000128404
si:ch1073-340i21.3
si:ch1073-340i21.3
chr23_+_44883805 0.43 ENSDART00000182805
si:ch73-361h17.1
si:ch73-361h17.1
chr7_+_34794829 0.39 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr8_-_1219815 0.38 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr3_-_25377163 0.37 ENSDART00000055490
kpna2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr6_-_34958274 0.36 ENSDART00000113097
hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
chr12_+_10706772 0.32 ENSDART00000158227
top2a
DNA topoisomerase II alpha
chr3_-_24681404 0.31 ENSDART00000161612
BX569789.1

chr14_-_12071447 0.31 ENSDART00000166116
tmsb1
thymosin beta 1
chr14_-_12071679 0.30 ENSDART00000165581
tmsb1
thymosin beta 1
chr7_+_26549846 0.30 ENSDART00000141353
tnk1
tyrosine kinase, non-receptor, 1
chr18_+_62932 0.30 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr3_+_1167026 0.28 ENSDART00000031823
ENSDART00000155340
triobpb
TRIO and F-actin binding protein b
chr10_+_39084354 0.28 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr20_-_2641233 0.28 ENSDART00000145335
ENSDART00000133121
bub1
BUB1 mitotic checkpoint serine/threonine kinase
chr7_-_22981796 0.28 ENSDART00000167565
si:dkey-171c9.3
si:dkey-171c9.3
chr23_+_32028574 0.27 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr18_+_30567945 0.27 ENSDART00000078894
irf8
interferon regulatory factor 8
chr21_-_26490186 0.27 ENSDART00000009889
zgc:110540
zgc:110540
chr25_-_4148719 0.26 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr10_+_6010570 0.26 ENSDART00000190025
ENSDART00000163680
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr16_-_12060770 0.26 ENSDART00000183237
ENSDART00000103948
si:ch211-69g19.2
si:ch211-69g19.2
chr19_+_791538 0.25 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr22_-_22301672 0.25 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr13_+_2394534 0.25 ENSDART00000172535
ENSDART00000006990
elovl5
ELOVL fatty acid elongase 5
chr9_-_1604601 0.25 ENSDART00000143130
agps
alkylglycerone phosphate synthase
chr22_+_38173960 0.25 ENSDART00000010537
cp
ceruloplasmin
chr19_+_56351 0.24 ENSDART00000168334
col14a1b
collagen, type XIV, alpha 1b
chr6_+_102506 0.24 ENSDART00000172678
ldlrb
low density lipoprotein receptor b
chr12_+_8822717 0.23 ENSDART00000021628
reep3b
receptor accessory protein 3b
chr5_+_24086227 0.23 ENSDART00000051549
ENSDART00000177458
ENSDART00000135934
tp53
tumor protein p53
chr13_+_2394264 0.23 ENSDART00000168595
elovl5
ELOVL fatty acid elongase 5
chr14_+_3038473 0.22 ENSDART00000026021
ENSDART00000150000
cd74a
CD74 molecule, major histocompatibility complex, class II invariant chain a
chr3_-_62403550 0.22 ENSDART00000055055
sox8b
SRY (sex determining region Y)-box 8b
chr6_+_56147812 0.22 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr20_+_16743056 0.21 ENSDART00000050308
calm1b
calmodulin 1b
chr5_-_14500622 0.21 ENSDART00000099566
si:ch211-244o22.2
si:ch211-244o22.2
chr3_+_17951790 0.21 ENSDART00000164663
aclya
ATP citrate lyase a
chr16_-_12060488 0.21 ENSDART00000188733
si:ch211-69g19.2
si:ch211-69g19.2
chr18_+_5490668 0.20 ENSDART00000167035
mibp2
muscle-specific beta 1 integrin binding protein 2
chr8_-_4508248 0.20 ENSDART00000141915
si:ch211-166a6.5
si:ch211-166a6.5
chr2_+_105748 0.20 ENSDART00000169601
CABZ01098670.1

chr4_-_76370630 0.20 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr22_-_4439311 0.19 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr7_+_57088920 0.19 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr4_+_4079418 0.19 ENSDART00000028016
waslb
Wiskott-Aldrich syndrome-like b
chr25_+_36312459 0.18 ENSDART00000182484
CR354435.5

chr6_-_25952848 0.18 ENSDART00000076997
ENSDART00000148748
lmo4b
LIM domain only 4b
chr3_-_32541033 0.18 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr7_+_22982201 0.17 ENSDART00000134116
ccnb3
cyclin B3
chr19_+_43004408 0.17 ENSDART00000038230
snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr21_+_944715 0.17 ENSDART00000144766
nars
asparaginyl-tRNA synthetase
chr7_+_22981909 0.17 ENSDART00000122449
ccnb3
cyclin B3
chr5_+_26138313 0.17 ENSDART00000010041
dhfr
dihydrofolate reductase
chr11_-_27778831 0.17 ENSDART00000023823
cass4
Cas scaffolding protein family member 4
chr14_-_40821411 0.16 ENSDART00000166621
elf1
E74-like ETS transcription factor 1
chr16_+_68069 0.16 ENSDART00000185385
ENSDART00000159652
sox4b
SRY (sex determining region Y)-box 4b
chr3_-_8765165 0.16 ENSDART00000191131
CABZ01058333.1

chr8_+_8927870 0.15 ENSDART00000081985
pim2
Pim-2 proto-oncogene, serine/threonine kinase
chr1_+_58840889 0.15 ENSDART00000098308
tmed1b
transmembrane p24 trafficking protein 1b
chr11_-_40519886 0.15 ENSDART00000172819
miip
migration and invasion inhibitory protein
chr20_-_49889111 0.15 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr2_-_58193381 0.15 ENSDART00000159040
pnp5b
purine nucleoside phosphorylase 5b
chr9_+_2499627 0.15 ENSDART00000160782
wipf1a
WAS/WASL interacting protein family, member 1a
chr1_+_54069450 0.15 ENSDART00000108601
ENSDART00000187878
dcaf15
DDB1 and CUL4 associated factor 15
chr24_+_17334682 0.14 ENSDART00000018868
pdia4
protein disulfide isomerase family A, member 4
chr11_+_14321113 0.13 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
ptbp1b
polypyrimidine tract binding protein 1b
chr12_-_10674606 0.12 ENSDART00000157919
med24
mediator complex subunit 24
chr10_-_35257458 0.12 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr1_-_51710225 0.12 ENSDART00000057601
ENSDART00000152745
snrpb2
small nuclear ribonucleoprotein polypeptide B2
chr11_+_18612166 0.12 ENSDART00000162694
ncoa3
nuclear receptor coactivator 3
chr22_-_36875264 0.12 ENSDART00000137548
kng1
kininogen 1
chr8_-_39884359 0.12 ENSDART00000131372
mlec
malectin
chr1_+_54037077 0.12 ENSDART00000109386
triobpa
TRIO and F-actin binding protein a
chr9_+_45227028 0.11 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr6_-_218882 0.11 ENSDART00000008398
c1qtnf6b
C1q and TNF related 6b
chr19_-_27334394 0.11 ENSDART00000052359
gtf2h4
general transcription factor IIH, polypeptide 4
chr11_-_10456387 0.11 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr21_+_244503 0.11 ENSDART00000162889
stard4
StAR-related lipid transfer (START) domain containing 4
chr20_+_50061890 0.11 ENSDART00000137725
cpsf2
cleavage and polyadenylation specific factor 2
chr18_+_17600570 0.11 ENSDART00000175258
ENSDART00000151850
ENSDART00000151934
herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr12_+_24060894 0.11 ENSDART00000021298
asb3
ankyrin repeat and SOCS box containing 3
chr9_-_2572790 0.11 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr12_-_48671612 0.11 ENSDART00000007202
zgc:92749
zgc:92749
chr18_-_18942098 0.11 ENSDART00000100458
si:dkey-73n10.1
si:dkey-73n10.1
chr18_+_7073130 0.10 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr1_-_54971968 0.10 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr19_+_5640504 0.10 ENSDART00000179987
ft2
alpha(1,3)fucosyltransferase gene 2
chr11_-_15297129 0.10 ENSDART00000167985
ENSDART00000163031
ENSDART00000165010
ENSDART00000171250
ENSDART00000010684
ENSDART00000191714
ENSDART00000191164
rpn2
ribophorin II
chr7_-_18617187 0.10 ENSDART00000172419
si:ch211-119e14.1
si:ch211-119e14.1
chr16_+_49647402 0.10 ENSDART00000015694
ENSDART00000132547
rab5ab
RAB5A, member RAS oncogene family, b
chr10_+_29816681 0.10 ENSDART00000100022
h2afx1
H2A histone family member X1
chr24_-_39772045 0.10 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr1_+_12394205 0.10 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
zgc:77739
chr11_+_26375979 0.10 ENSDART00000087652
ENSDART00000171748
ENSDART00000103513
ENSDART00000165931
ENSDART00000170043
cpne1
rbm12
copine I
RNA binding motif protein 12
chr11_-_44945636 0.10 ENSDART00000157658
orc2
origin recognition complex, subunit 2
chr24_-_39186185 0.10 ENSDART00000123019
ENSDART00000191114
nubp2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr10_+_36026576 0.10 ENSDART00000193786
hmgb1a
high mobility group box 1a
chr1_-_20928772 0.10 ENSDART00000078277
msmo1
methylsterol monooxygenase 1
chr3_-_61218272 0.10 ENSDART00000133091
ENSDART00000055068
pvalb5
parvalbumin 5
chr11_-_10456553 0.10 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr18_+_2563756 0.10 ENSDART00000164147
p2ry2.1
purinergic receptor P2Y2, tandem duplicate 1
chr5_-_2721686 0.09 ENSDART00000169404
hspa5
heat shock protein 5
chr18_+_50089000 0.09 ENSDART00000058936
scamp5b
secretory carrier membrane protein 5b
chr19_+_12234975 0.09 ENSDART00000149221
grhl2b
grainyhead-like transcription factor 2b
chr3_+_16664212 0.09 ENSDART00000013816
zgc:55558
zgc:55558
chr7_+_73819078 0.09 ENSDART00000169756
FP236812.1
Histone H2B 1/2
chr21_-_5007109 0.09 ENSDART00000187042
ENSDART00000097796
ENSDART00000146766
rnf165a
ring finger protein 165a
chr13_-_856701 0.09 ENSDART00000140423
TMEM14A
zgc:163080
chr7_+_22981441 0.09 ENSDART00000182887
ccnb3
cyclin B3
chr4_-_9196291 0.09 ENSDART00000153963
hcfc2
host cell factor C2
chr16_-_39477746 0.09 ENSDART00000102525
stt3b
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr14_-_16476863 0.09 ENSDART00000089021
canx
calnexin
chr23_-_41651759 0.09 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr7_+_24390939 0.08 ENSDART00000087494
ENSDART00000125463
haus3
HAUS augmin-like complex, subunit 3
chr1_+_43686251 0.08 ENSDART00000074604
ENSDART00000137791
cisd2
CDGSH iron sulfur domain 2
chr21_-_1635268 0.08 ENSDART00000151258
zgc:152948
zgc:152948
chr7_+_57108823 0.08 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr11_-_15296805 0.08 ENSDART00000124968
rpn2
ribophorin II
chr1_-_54972170 0.08 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr13_-_856525 0.08 ENSDART00000143356
TMEM14A
zgc:163080
chr7_+_5906327 0.08 ENSDART00000173160
zgc:112234
zgc:112234
chr1_-_18803919 0.08 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr7_-_6466119 0.08 ENSDART00000173138
zgc:112234
zgc:112234
chr17_+_31221761 0.08 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr25_+_5983430 0.08 ENSDART00000074814
ppib
peptidylprolyl isomerase B (cyclophilin B)
chr8_+_53269657 0.08 ENSDART00000184212
gnb1a
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr13_-_42536642 0.08 ENSDART00000134533
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr15_-_43287515 0.07 ENSDART00000155103
prss16
protease, serine, 16 (thymus)
chr21_+_3897680 0.07 ENSDART00000170653
dolpp1
dolichyldiphosphatase 1
chr11_+_35050253 0.07 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr7_-_6364168 0.07 ENSDART00000173332
zgc:112234
zgc:112234
chr14_-_12020653 0.07 ENSDART00000106654
znf711
zinc finger protein 711
chr16_+_33144306 0.07 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr18_+_16986903 0.07 ENSDART00000142088
si:ch211-218c6.8
si:ch211-218c6.8
chr18_+_44795711 0.07 ENSDART00000110229
ENSDART00000188262
ENSDART00000139526
fam118b
family with sequence similarity 118, member B
chr23_-_4930229 0.07 ENSDART00000189456
ngfa
nerve growth factor a (beta polypeptide)
chr14_+_1170968 0.07 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr6_+_3710865 0.07 ENSDART00000170781
phospho2
phosphatase, orphan 2
chr25_-_17918536 0.07 ENSDART00000148660
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr19_+_14109348 0.07 ENSDART00000159015
zgc:175136
zgc:175136
chr16_-_11241424 0.07 ENSDART00000134752
znf526
zinc finger protein 526
chr7_-_73834812 0.07 ENSDART00000128137
zgc:92594
zgc:92594
chr2_+_24868010 0.07 ENSDART00000078838
rab3aa
RAB3A, member RAS oncogene family, a
chr4_-_5247335 0.07 ENSDART00000050221
atp6v1e1b
ATPase H+ transporting V1 subunit E1b
chr1_-_33557915 0.06 ENSDART00000075632
creb1a
cAMP responsive element binding protein 1a
chr25_+_25508495 0.06 ENSDART00000150719
phrf1
PHD and ring finger domains 1
chr9_-_2573121 0.06 ENSDART00000181340
scrn3
secernin 3
chr22_-_24248420 0.06 ENSDART00000165433
rgs2
regulator of G protein signaling 2
chr20_-_7176809 0.06 ENSDART00000012247
ENSDART00000125019
dhcr24
24-dehydrocholesterol reductase
chr6_-_50704689 0.06 ENSDART00000074100
osgn1
oxidative stress induced growth inhibitor 1
chr3_+_36671585 0.06 ENSDART00000159033
nde1
nudE neurodevelopment protein 1
chr7_+_73827805 0.06 ENSDART00000109316
zgc:173587
zgc:173587
chr25_-_6261693 0.06 ENSDART00000135808
ireb2
iron-responsive element binding protein 2
chr25_-_36361697 0.06 ENSDART00000152388
si:ch211-113a14.22
si:ch211-113a14.22
chr1_+_54737353 0.06 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr1_-_9644630 0.06 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr23_+_36616717 0.05 ENSDART00000042701
ENSDART00000192980
pip4k2ca
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr22_+_17205608 0.05 ENSDART00000181267
rab3b
RAB3B, member RAS oncogene family
chr7_+_39360797 0.05 ENSDART00000173481
acp2
acid phosphatase 2, lysosomal
chr9_-_12595003 0.05 ENSDART00000184900
tra2b
transformer 2 beta homolog
chr6_+_269204 0.05 ENSDART00000191678
atf4a
activating transcription factor 4a
chr19_-_1855368 0.05 ENSDART00000029646
rplp1
ribosomal protein, large, P1
chr20_-_52939501 0.05 ENSDART00000166508
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr2_-_17115256 0.05 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr16_-_52646789 0.05 ENSDART00000035761
ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr16_+_33144112 0.05 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr8_-_1266181 0.05 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr25_-_17918810 0.05 ENSDART00000023959
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr21_-_1642739 0.05 ENSDART00000151118
zgc:152948
zgc:152948
chr1_+_30723677 0.05 ENSDART00000177900
bora
bora, aurora kinase A activator
chr2_+_24867534 0.05 ENSDART00000158050
rab3aa
RAB3A, member RAS oncogene family, a
chr18_-_26894732 0.05 ENSDART00000147735
ENSDART00000188938
BX470164.1
si:dkey-24l11.2

si:dkey-24l11.2
chr20_+_18703108 0.05 ENSDART00000181188
eif5
eukaryotic translation initiation factor 5
chr4_+_13449775 0.05 ENSDART00000172552
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr7_-_31794476 0.05 ENSDART00000142385
nap1l4b
nucleosome assembly protein 1-like 4b
chr1_-_54063520 0.05 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr16_-_39477509 0.05 ENSDART00000191330
stt3b
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr19_-_43004356 0.05 ENSDART00000098101
zcchc17
zinc finger, CCHC domain containing 17
chr16_+_4838808 0.04 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_-_17492080 0.04 ENSDART00000024302
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr1_+_30723380 0.04 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora
bora, aurora kinase A activator
chr19_-_6134802 0.04 ENSDART00000140051
cica
capicua transcriptional repressor a
chr8_+_49766338 0.04 ENSDART00000060657
rmi1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr21_+_19070921 0.04 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr15_+_25438714 0.04 ENSDART00000154164
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr25_-_35110695 0.04 ENSDART00000099859
hist1h2a10
histone cluster 1 H2A family member 10
chr7_+_5965611 0.04 ENSDART00000115062
CU459186.2
Histone H3.2
chr3_-_1146497 0.03 ENSDART00000149061
si:ch73-211l13.2
si:ch73-211l13.2
chr9_-_12594759 0.03 ENSDART00000021266
tra2b
transformer 2 beta homolog
chr3_-_10751491 0.03 ENSDART00000016351
zgc:112965
zgc:112965
chr25_+_35051656 0.03 ENSDART00000133379
hist2h3c
histone cluster 2, H3c
chr10_-_15644904 0.03 ENSDART00000138389
ENSDART00000101191
ENSDART00000186559
ENSDART00000122170
smc5
structural maintenance of chromosomes 5
chr8_-_44015210 0.03 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr7_+_5976613 0.03 ENSDART00000173105
si:dkey-23a13.21
si:dkey-23a13.21
chr10_+_7703251 0.03 ENSDART00000165134
ggcx
gamma-glutamyl carboxylase
chr15_-_6615555 0.03 ENSDART00000152725
atm
ATM serine/threonine kinase
chr17_-_6514962 0.03 ENSDART00000163514
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b

Network of associatons between targets according to the STRING database.

First level regulatory network of ybx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0009838 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 0.3 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.3 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:0032197 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.2 GO:0010935 dendritic cell antigen processing and presentation(GO:0002468) macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.1 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.6 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle