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PRJNA207719: Tissue specific transcriptome profiling

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Results for zbtb49

Z-value: 0.75

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Transcription factors associated with zbtb49

Gene Symbol Gene ID Gene Info
zbtb49
ENSDARG00000102111 zinc finger and BTB domain containing 49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb49dr11_v1_chr14_-_30050_300500.856.8e-02Click!

Activity profile of zbtb49 motif

Sorted Z-values of zbtb49 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22823889 0.78 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
pygmb
phosphorylase, glycogen, muscle b
chr8_+_25302172 0.43 ENSDART00000046182
ENSDART00000145316
gstm.3
glutathione S-transferase mu tandem duplicate 3
chr8_+_36582728 0.38 ENSDART00000049230
pqbp1
polyglutamine binding protein 1
chr8_+_36582915 0.35 ENSDART00000139482
pqbp1
polyglutamine binding protein 1
chr18_-_44129151 0.34 ENSDART00000087339
cdon
cell adhesion associated, oncogene regulated
chr13_-_2283176 0.33 ENSDART00000158462
lrrc1
leucine rich repeat containing 1
chr7_-_38340674 0.26 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr21_-_22673758 0.25 ENSDART00000164910
gig2i
grass carp reovirus (GCRV)-induced gene 2i
chr10_-_15919839 0.24 ENSDART00000065032
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr9_+_8942258 0.23 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr14_+_33882973 0.22 ENSDART00000019396
clic2
chloride intracellular channel 2
chr22_+_12798569 0.22 ENSDART00000005720
stat1a
signal transducer and activator of transcription 1a
chr20_-_10120442 0.22 ENSDART00000144970
meis2b
Meis homeobox 2b
chr12_+_26632448 0.18 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr13_+_51853716 0.17 ENSDART00000175341
ENSDART00000187855
LT631684.1

chr8_-_38477817 0.16 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr3_-_13461056 0.14 ENSDART00000137678
fbxw9
F-box and WD repeat domain containing 9
chr14_-_49896795 0.14 ENSDART00000168142
ube2d2l
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like
chr7_-_44794322 0.14 ENSDART00000019270
nae1
nedd8 activating enzyme E1 subunit 1
chr11_+_8565323 0.13 ENSDART00000081607
ENSDART00000141612
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr17_+_25590127 0.11 ENSDART00000064803
iars2
isoleucyl-tRNA synthetase 2, mitochondrial
chr1_-_38709551 0.11 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr15_-_2734560 0.10 ENSDART00000153853
ppp5c
protein phosphatase 5, catalytic subunit
chr21_-_22676323 0.09 ENSDART00000167392
gig2h
grass carp reovirus (GCRV)-induced gene 2h
chr18_-_370286 0.08 ENSDART00000162633
si:ch211-79l17.1
si:ch211-79l17.1
chr17_+_8925232 0.07 ENSDART00000036668
psmc1a
proteasome 26S subunit, ATPase 1a
chr6_-_55399214 0.06 ENSDART00000168367
ctsa
cathepsin A
chr24_-_3419998 0.06 ENSDART00000066839
slc35g2b
solute carrier family 35, member G2b
chr22_+_10158502 0.05 ENSDART00000005869
rpp14
ribonuclease P/MRP 14 subunit
chr7_-_52334840 0.05 ENSDART00000174173
CR938716.1

chr23_+_14673922 0.04 ENSDART00000185086
si:rp71-79p20.2
si:rp71-79p20.2
chr14_+_16093889 0.03 ENSDART00000159181
immt
inner membrane protein, mitochondrial (mitofilin)
chr9_+_38629962 0.03 ENSDART00000184890
znf148
zinc finger protein 148
chr7_-_31941670 0.03 ENSDART00000180929
ENSDART00000075389
bdnf
brain-derived neurotrophic factor
chr2_+_9973687 0.02 ENSDART00000043499
sec22ba
SEC22 homolog B, vesicle trafficking protein a
chr21_+_25181003 0.02 ENSDART00000169700
si:dkey-183i3.9
si:dkey-183i3.9
chr9_+_29430432 0.01 ENSDART00000125632
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr7_-_5148388 0.00 ENSDART00000143549
si:ch211-272h9.5
si:ch211-272h9.5

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb49

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.1 0.3 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family