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PRJNA207719: Tissue specific transcriptome profiling

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Results for zeb1a+zeb1b

Z-value: 4.85

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Transcription factors associated with zeb1a+zeb1b

Gene Symbol Gene ID Gene Info
ENSDARG00000013207 zinc finger E-box binding homeobox 1b
ENSDARG00000016788 zinc finger E-box binding homeobox 1a
ENSDARG00000113922 zinc finger E-box binding homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zeb1bdr11_v1_chr12_-_26851726_26851726-0.857.0e-02Click!
zeb1adr11_v1_chr2_-_43850637_43850637-0.751.5e-01Click!

Activity profile of zeb1a+zeb1b motif

Sorted Z-values of zeb1a+zeb1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_20239141 6.92 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr22_+_661711 4.88 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_-_30404096 4.75 ENSDART00000103475
anterior gradient 2
chr2_+_68789 4.58 ENSDART00000058569
claudin 1
chr22_+_7439476 4.51 ENSDART00000021594
ENSDART00000063389
zgc:92041
chr22_+_1170294 4.47 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr10_-_2942900 4.25 ENSDART00000002622
occludin a
chr6_-_7776612 4.20 ENSDART00000190269
myosin, heavy chain 9a, non-muscle
chr21_-_38153824 3.90 ENSDART00000151226
Kruppel-like factor 5 like
chr19_-_30403922 3.87 ENSDART00000181841
anterior gradient 2
chr22_+_661505 3.78 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr1_-_50247 3.47 ENSDART00000168428
immunoglobulin-like domain containing receptor 1a
chr9_+_48007081 3.40 ENSDART00000060593
ENSDART00000099835
zgc:92380
chr16_+_17715243 3.39 ENSDART00000149437
ENSDART00000149596
si:dkey-87o1.2
chr22_-_17677947 3.37 ENSDART00000139911
tight junction protein 3
chr16_-_26676685 3.28 ENSDART00000103431
epithelial splicing regulatory protein 1
chr25_-_22187397 3.26 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr15_-_33964897 3.16 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lipolysis stimulated lipoprotein receptor
chr19_-_48010490 3.10 ENSDART00000159938
zgc:158376
chr19_-_48312109 3.04 ENSDART00000161103
si:ch73-359m17.9
chr19_+_791538 2.99 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr3_-_61162750 2.98 ENSDART00000055064
parvalbumin 8
chr2_-_722156 2.90 ENSDART00000045770
ENSDART00000169498
forkhead box Q1a
chr7_-_53117131 2.86 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr8_-_18667693 2.82 ENSDART00000100516
signal transducing adaptor family member 2b
chr16_-_23346095 2.77 ENSDART00000160546
si:dkey-247k7.2
chr13_+_33606739 2.73 ENSDART00000026464
cofilin 1 (non-muscle), like
chr16_+_23947196 2.71 ENSDART00000103190
ENSDART00000132961
ENSDART00000147690
ENSDART00000142168
apolipoprotein A-IV b, tandem duplicate 2
chr12_-_4243268 2.61 ENSDART00000131275
zgc:92313
chr21_-_25741411 2.60 ENSDART00000101211
claudin h
chr11_+_10984293 2.58 ENSDART00000065933
integrin, beta 6
chr7_+_35075847 2.56 ENSDART00000193469
ENSDART00000037346
chymotrypsinogen B1
chr7_-_55648336 2.50 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr17_+_2549503 2.45 ENSDART00000156843
si:dkey-248g15.3
chr4_-_77557279 2.44 ENSDART00000180113

chr12_-_46228023 2.41 ENSDART00000153455
si:ch211-226h7.6
chr22_+_11756040 2.39 ENSDART00000105808
keratin 97
chr12_-_11349899 2.37 ENSDART00000079645
zgc:174164
chr5_-_65021736 2.37 ENSDART00000162368
ENSDART00000161876
annexin A1c
chr10_+_2715548 2.34 ENSDART00000130793
G protein-coupled receptor kinase 5
chr12_-_46252062 2.33 ENSDART00000153223
si:ch211-226h7.5
chr3_-_33970190 2.30 ENSDART00000151238
ighj2-5
chr22_+_7439186 2.28 ENSDART00000190667
zgc:92041
chr17_-_32426392 2.26 ENSDART00000148455
ENSDART00000149885
ENSDART00000179314
grainyhead-like transcription factor 1
chr1_+_56180416 2.23 ENSDART00000089358
crumbs homolog 3b
chr15_-_107900 2.22 ENSDART00000193184
apolipoprotein A-Ib
chr16_-_20312146 2.22 ENSDART00000134980
si:dkeyp-86h10.3
chr17_-_2596125 2.20 ENSDART00000175740
zona pellucida glycoprotein 3, tandem duplicate 2
chr2_+_15612755 2.19 ENSDART00000003035
amylase, alpha 2A (pancreatic)
chr25_+_22107643 2.18 ENSDART00000089680
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr14_+_48862987 2.15 ENSDART00000167810
zgc:154054
chr21_+_30351256 2.15 ENSDART00000078341
forkhead box I3a
chr22_-_15578402 2.14 ENSDART00000062986
hematopoietic SH2 domain containing
chr1_+_58922027 2.14 ENSDART00000159479
thyroid hormone receptor interactor 10b
chr22_+_7480465 2.14 ENSDART00000034545
zgc:92745
chr13_+_24750078 2.12 ENSDART00000021053
collagen, type XVII, alpha 1b
chr19_+_10855158 2.11 ENSDART00000172219
ENSDART00000170826
apolipoprotein Ea
chr1_-_45177373 2.10 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr24_-_20444844 2.09 ENSDART00000048940
villin-like
chr22_+_3914318 2.03 ENSDART00000188774
ENSDART00000082034
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr5_-_37959874 1.97 ENSDART00000031719
myelin protein zero-like 2b
chr19_-_5332784 1.97 ENSDART00000010373
keratin, type 1, gene 19d
chr10_-_34002185 1.95 ENSDART00000046599
zygote arrest 1-like
chr21_-_22648007 1.92 ENSDART00000121788
grass carp reovirus (GCRV)-induced gene 2l
chr3_-_19561058 1.91 ENSDART00000079323
zgc:163079
chr17_+_2552453 1.89 ENSDART00000189889
si:dkey-248g15.3
chr12_+_5708400 1.89 ENSDART00000017191
distal-less homeobox 3b
chr11_-_11518469 1.88 ENSDART00000104254
keratin 15
chr17_-_26867725 1.88 ENSDART00000153590
si:dkey-221l4.10
chr23_-_10175898 1.86 ENSDART00000146185
keratin 5
chr17_-_30652738 1.86 ENSDART00000154960
SH3 and SYLF domain containing 1
chr11_+_37216668 1.85 ENSDART00000173076
zgc:112265
chr22_+_7497319 1.83 ENSDART00000034564
zgc:92511
chr25_-_169291 1.80 ENSDART00000128344
lipase, hepatic b
chr1_-_52437056 1.78 ENSDART00000138337
si:ch211-217k17.12
chr19_-_40198478 1.78 ENSDART00000191736
granulin 2
chr4_-_68563862 1.77 ENSDART00000182970

chr4_+_76671012 1.76 ENSDART00000005585
membrane-spanning 4-domains, subfamily A, member 17a.2
chr16_+_23921777 1.75 ENSDART00000163213
apolipoprotein A-IV b, tandem duplicate 3
chr21_-_30293224 1.74 ENSDART00000101051
stem-loop binding protein 2
chr15_-_43164591 1.71 ENSDART00000171305
adaptor-related protein complex 1, sigma 3 subunit, a
chr18_-_46354269 1.71 ENSDART00000010813
forkhead box A3
chr15_-_41714329 1.70 ENSDART00000154113

chr10_-_35149513 1.70 ENSDART00000063434
ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr1_-_2051599 1.69 ENSDART00000041936
oxoglutarate (alpha-ketoglutarate) receptor 1a, tandem duplicate 1
chr1_-_45146834 1.68 ENSDART00000144997
si:ch211-239f4.6
chr8_+_2478862 1.68 ENSDART00000131739
si:dkeyp-51b9.3
chr16_+_23921610 1.67 ENSDART00000143855
apolipoprotein A-IV b, tandem duplicate 3
chr4_-_68564988 1.67 ENSDART00000191212

chr24_-_31904924 1.66 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr18_-_38271298 1.65 ENSDART00000143016
cell cycle associated protein 1b
chr17_+_26965351 1.65 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr25_-_17395315 1.64 ENSDART00000064596
cytochrome P450, family 2, subfamily X, polypeptide 8
chr20_-_3238110 1.64 ENSDART00000008077
serine peptidase inhibitor, Kunitz type 1 b
chr20_+_1398564 1.63 ENSDART00000002242
liver-enriched gene 1, tandem duplicate 2
chr21_-_25741096 1.62 ENSDART00000181756
claudin h
chr11_-_45429199 1.62 ENSDART00000173111
replication factor C (activator 1) 4
chr14_+_14568437 1.61 ENSDART00000164749
protocadherin 20
chr20_-_42702832 1.60 ENSDART00000134689
ENSDART00000045816
plasminogen
chr12_-_46315898 1.60 ENSDART00000153138
si:ch211-226h7.3
chr3_-_33970998 1.60 ENSDART00000151527
immunoglobulin heavy joining 2-2
chr16_+_17714664 1.59 ENSDART00000149042
si:dkey-87o1.2
chr8_+_25302172 1.58 ENSDART00000046182
ENSDART00000145316
glutathione S-transferase mu tandem duplicate 3
chr22_+_7472420 1.57 ENSDART00000132049
si:dkey-57c15.4
chr1_+_26411496 1.57 ENSDART00000112263
Rho guanine nucleotide exchange factor (GEF) 38
chr7_+_30392613 1.57 ENSDART00000075508
lipase, hepatic a
chr21_-_7928101 1.56 ENSDART00000151543
ENSDART00000114982
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr2_+_49457626 1.55 ENSDART00000129967
SH3-domain GRB2-like 1a
chr2_+_49457449 1.54 ENSDART00000185470
SH3-domain GRB2-like 1a
chr20_+_1412193 1.54 ENSDART00000064419
liver-enriched gene 1, tandem duplicate 1
chr20_+_305035 1.54 ENSDART00000104807
si:dkey-119m7.4
chr5_+_26212621 1.53 ENSDART00000134432
occludin b
chr22_+_7742211 1.53 ENSDART00000140896
zgc:92511
chr7_-_34265481 1.51 ENSDART00000173596
si:ch211-98n17.5
chr7_-_38658411 1.51 ENSDART00000109463
ENSDART00000017155
nephrosin
chr15_-_47929455 1.50 ENSDART00000064462
proteasome subunit alpha 6, like
chr5_+_30384554 1.50 ENSDART00000135483
zgc:158412
chr23_+_31815423 1.50 ENSDART00000075730
ENSDART00000075726
v-myb avian myeloblastosis viral oncogene homolog
chr24_-_26369185 1.49 ENSDART00000080039
leucine rich repeat containing 31
chr25_+_10416583 1.49 ENSDART00000073907
ets homologous factor
chr16_-_42186093 1.49 ENSDART00000076030
fibrillarin
chr4_+_18843015 1.47 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
BCL2 interacting killer
chr17_+_24843401 1.47 ENSDART00000110179
connexin 34.4
chr8_-_11170114 1.46 ENSDART00000133532
si:ch211-204d2.4
chr16_+_28754403 1.46 ENSDART00000103340
S100 calcium binding protein V1
chr13_-_15994419 1.45 ENSDART00000079724
ENSDART00000042377
ENSDART00000046079
ENSDART00000050481
ENSDART00000016430
IKAROS family zinc finger 1 (Ikaros)
chr10_-_15053507 1.45 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr13_-_36034582 1.45 ENSDART00000133565
si:dkey-157l19.2
chr8_+_999421 1.45 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr3_+_49021079 1.45 ENSDART00000162012
zgc:163083
chr9_-_44948488 1.44 ENSDART00000059228
villin 1
chr23_-_29824146 1.44 ENSDART00000020616
zgc:194189
chr22_+_19494996 1.44 ENSDART00000140829
ENSDART00000135168
si:dkey-78l4.10
chr21_-_7940043 1.44 ENSDART00000099733
ENSDART00000136671
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr1_-_7951002 1.43 ENSDART00000138187
si:dkey-79f11.8
chr7_-_8416750 1.43 ENSDART00000181857
jacalin 1
chr2_-_32237916 1.43 ENSDART00000141418
family with sequence similarity 49, member Ba
chr4_-_178510 1.43 ENSDART00000169805
epidermal growth factor receptor pathway substrate 8
chr19_+_48141623 1.43 ENSDART00000170439
bloodthirsty-related gene family, member 30
chr17_+_43868441 1.42 ENSDART00000134272
zgc:66313
chr5_-_22590739 1.41 ENSDART00000141555
si:dkey-103e21.5
chr19_+_4800549 1.41 ENSDART00000056235
ST3 beta-galactoside alpha-2,3-sialyltransferase 1, like
chr1_-_7603734 1.41 ENSDART00000009315
myxovirus (influenza) resistance B
chr7_+_55149001 1.40 ENSDART00000148642
cadherin 31
chr15_-_108414 1.39 ENSDART00000170044
apolipoprotein A-Ib
chr23_+_46157638 1.38 ENSDART00000076048
bloodthirsty-related gene family, member 32
chr3_+_8224622 1.38 ENSDART00000138670
si:ch73-379f5.5
chr4_-_13518381 1.38 ENSDART00000067153
interferon, gamma 1-1
chr14_+_15543331 1.38 ENSDART00000167025
si:dkey-203a12.7
chr21_-_217589 1.38 ENSDART00000185017

chr21_-_3700334 1.37 ENSDART00000137844
ATPase phospholipid transporting 8B1
chr14_+_32964 1.37 ENSDART00000166173
Ly1 antibody reactive homolog (mouse)
chr13_+_18533005 1.36 ENSDART00000136024
finTRIM family, member 14-like
chr7_+_32901658 1.36 ENSDART00000115420
anoctamin 9b
chr7_+_73670137 1.36 ENSDART00000050357
bloodthirsty-related gene family, member 12
chr3_-_33970431 1.35 ENSDART00000151313
ighj2-4
chr3_+_21189766 1.35 ENSDART00000078807
zgc:123295
chr11_+_329687 1.34 ENSDART00000172882
cytochrome P450, family 27, subfamily B, polypeptide 1
chr15_-_576135 1.34 ENSDART00000124170
cerebellin 20
chr17_-_2595736 1.34 ENSDART00000128797
zona pellucida glycoprotein 3, tandem duplicate 2
chr18_+_44703343 1.33 ENSDART00000131510
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr1_+_59538755 1.33 ENSDART00000166354
Sp6 transcription factor
chr13_-_21672131 1.33 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr14_+_6953244 1.33 ENSDART00000159470
receptor for activated C kinase 1
chr20_+_26556174 1.32 ENSDART00000138492
interferon regulatory factor 4b
chr15_-_21165237 1.32 ENSDART00000157069
si:ch211-212c13.8
chr25_-_16600811 1.32 ENSDART00000011397
carboxypeptidase A2 (pancreatic)
chr25_+_3217419 1.32 ENSDART00000104859
RCC1 domain containing 1
chr6_-_609880 1.31 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr3_-_39488482 1.31 ENSDART00000135192
zgc:100868
chr16_-_9830451 1.31 ENSDART00000148528
grainyhead-like transcription factor 2a
chr6_+_153146 1.30 ENSDART00000097468
zinc finger, GATA-like protein 1
chr2_-_47620806 1.30 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr24_-_36593876 1.30 ENSDART00000160901

chr1_-_59095035 1.29 ENSDART00000130791
wu:fj11g02
chr7_+_66565930 1.29 ENSDART00000154597
transmembrane protein 176l.3b
chr16_-_46664465 1.29 ENSDART00000135364
transmembrane protein 176l.4
chr3_-_39488639 1.27 ENSDART00000161644
zgc:100868
chr5_-_67471375 1.27 ENSDART00000147009
si:dkey-251i10.2
chr17_-_42988356 1.27 ENSDART00000024558
zgc:92137
chr6_+_36877968 1.26 ENSDART00000155187
TRAF3 interacting protein 2-like
chr2_-_58075414 1.26 ENSDART00000161920
nectin cell adhesion molecule 4
chr4_-_12725513 1.25 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr14_+_22022441 1.25 ENSDART00000149121
cardiotrophin-like cytokine factor 1
chr22_+_2960280 1.25 ENSDART00000134188
ENSDART00000134451
ENSDART00000139894
impact RWD domain protein
chr2_-_8648440 1.25 ENSDART00000135743
si:ch211-71m22.3
chr7_+_35068036 1.25 ENSDART00000022139
zgc:136461
chr3_+_29469283 1.25 ENSDART00000103592
family with sequence similarity 83, member Fa
chr21_+_10577527 1.25 ENSDART00000165070
ENSDART00000127963
collagen and calcium binding EGF domains 1
chr6_-_33913184 1.25 ENSDART00000146373
nuclear autoantigenic sperm protein (histone-binding)
chr23_-_31428763 1.24 ENSDART00000053545
zgc:153284
chr5_-_33236637 1.24 ENSDART00000085512
ENSDART00000144694
KN motif and ankyrin repeat domains 1b
chr19_-_15192638 1.24 ENSDART00000048151
phosphatase and actin regulator 4a
chr12_+_20352400 1.23 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr16_+_13427967 1.23 ENSDART00000038196
zgc:101640
chr20_-_17041025 1.22 ENSDART00000063764
si:dkey-5n18.1
chr21_-_22676323 1.22 ENSDART00000167392
grass carp reovirus (GCRV)-induced gene 2h
chr10_+_9561066 1.22 ENSDART00000136281
si:ch211-243g18.2
chr18_-_977075 1.21 ENSDART00000032392
dihydrodiol dehydrogenase (dimeric), like
chr21_-_25295087 1.21 ENSDART00000087910
ENSDART00000147860
suppression of tumorigenicity 14 (colon carcinoma) b

Network of associatons between targets according to the STRING database.

First level regulatory network of zeb1a+zeb1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.4 GO:0061438 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
1.1 5.3 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.9 3.7 GO:0097242 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.9 2.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.9 8.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.8 3.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.6 1.9 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6 1.7 GO:0048785 hatching gland development(GO:0048785)
0.5 1.6 GO:0042730 fibrinolysis(GO:0042730)
0.5 3.0 GO:0003334 keratinocyte development(GO:0003334)
0.5 2.9 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.5 1.4 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.4 1.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.4 2.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 3.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 2.4 GO:2000516 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.4 2.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 1.9 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.4 1.1 GO:0002369 T cell cytokine production(GO:0002369)
0.4 3.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.4 3.4 GO:0030104 water homeostasis(GO:0030104)
0.4 1.4 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.4 6.1 GO:2000344 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 1.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.0 GO:0000103 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 1.0 GO:0030237 female sex determination(GO:0030237)
0.3 0.3 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) RNA 5'-end processing(GO:0000966) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.3 0.9 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.3 1.7 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 0.8 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 1.0 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.5 GO:0010269 response to selenium ion(GO:0010269)
0.3 1.3 GO:0070301 response to acidic pH(GO:0010447) cellular response to hydrogen peroxide(GO:0070301)
0.2 0.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 1.5 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.2 2.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 11.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 1.1 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 1.1 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.2 0.2 GO:0032768 regulation of monooxygenase activity(GO:0032768) positive regulation of monooxygenase activity(GO:0032770)
0.2 1.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 0.7 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.2 0.7 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 1.3 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 0.6 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 1.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.6 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 2.0 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.2 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 1.2 GO:0007608 sensory perception of smell(GO:0007608)
0.2 0.6 GO:0065001 specification of axis polarity(GO:0065001)
0.2 0.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 1.2 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.2 2.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 4.9 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.2 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 1.8 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 1.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 2.2 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 5.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.2 0.5 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.2 0.7 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.2 0.9 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 4.2 GO:0051014 actin filament severing(GO:0051014)
0.2 1.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 3.3 GO:0030183 B cell differentiation(GO:0030183)
0.2 1.0 GO:0046874 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.2 1.5 GO:1990402 embryonic liver development(GO:1990402)
0.2 0.7 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.2 0.2 GO:0061010 gall bladder development(GO:0061010)
0.2 1.0 GO:0070254 mucus secretion(GO:0070254)
0.2 0.7 GO:1902745 positive regulation of lamellipodium organization(GO:1902745)
0.2 1.0 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 0.5 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 0.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.2 2.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 0.5 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 1.5 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.2 0.8 GO:0042554 superoxide anion generation(GO:0042554)
0.2 0.8 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 0.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.2 0.5 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.2 4.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 0.9 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 0.5 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.2 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 1.1 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.2 0.9 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.2 2.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 1.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 3.0 GO:0006183 GTP biosynthetic process(GO:0006183)
0.1 1.5 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.7 GO:0006833 water transport(GO:0006833)
0.1 0.4 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.4 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 3.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.4 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.1 0.7 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 0.4 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.1 1.0 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.4 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.7 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 0.4 GO:0098801 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093) regulation of renal system process(GO:0098801)
0.1 0.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.9 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 2.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.4 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.1 0.7 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.3 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 0.5 GO:0046100 hypoxanthine metabolic process(GO:0046100)
0.1 0.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 0.5 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 1.2 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.9 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.5 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.1 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.4 GO:0055057 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.1 0.7 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 1.3 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.5 GO:0033273 response to vitamin(GO:0033273)
0.1 1.8 GO:0031641 regulation of myelination(GO:0031641)
0.1 0.8 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 14.1 GO:1990266 neutrophil migration(GO:1990266)
0.1 0.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 2.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.7 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.8 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 2.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.8 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.1 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 1.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 1.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.1 2.0 GO:0001843 neural tube closure(GO:0001843)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.8 GO:0050892 intestinal absorption(GO:0050892)
0.1 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.6 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 2.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.4 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 1.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.7 GO:0061511 centriole elongation(GO:0061511)
0.1 1.0 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.3 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.3 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 0.4 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.8 GO:0031179 peptide modification(GO:0031179)
0.1 2.8 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 2.2 GO:0043588 skin development(GO:0043588)
0.1 0.7 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.8 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.1 0.6 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.4 GO:0006272 leading strand elongation(GO:0006272)
0.1 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.9 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 0.3 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.1 GO:0032366 intracellular sterol transport(GO:0032366)
0.1 0.6 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.8 GO:0042531 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 5.9 GO:0007492 endoderm development(GO:0007492)
0.1 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.3 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.9 GO:0030719 P granule organization(GO:0030719)
0.1 0.5 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.8 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
0.1 0.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 1.3 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.6 GO:0060872 semicircular canal development(GO:0060872)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.8 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.7 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.3 GO:0006953 acute-phase response(GO:0006953)
0.1 0.4 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.1 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.6 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 3.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.4 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.7 GO:0051601 exocyst localization(GO:0051601)
0.1 1.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.5 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 0.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.7 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 3.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.5 GO:0016556 mRNA modification(GO:0016556)
0.1 0.3 GO:0090208 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867) positive regulation of triglyceride metabolic process(GO:0090208)
0.1 1.0 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 1.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.2 GO:0070285 pigment cell development(GO:0070285)
0.1 0.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.2 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 0.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 1.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.2 GO:0070197 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0001840 neural plate development(GO:0001840)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.6 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.7 GO:0008354 germ cell migration(GO:0008354)
0.1 0.5 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.9 GO:0036065 fucosylation(GO:0036065)
0.1 1.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.7 GO:0031297 replication fork processing(GO:0031297)
0.1 0.4 GO:0072048 anterior/posterior pattern specification involved in pronephros development(GO:0034672) pattern specification involved in pronephros development(GO:0039017) pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.8 GO:0042476 odontogenesis(GO:0042476)
0.1 0.2 GO:0046755 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 7.3 GO:0006954 inflammatory response(GO:0006954)
0.1 0.8 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 5.2 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.4 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.1 0.2 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 2.6 GO:0010950 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 5.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.8 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.3 GO:0045444 fat cell differentiation(GO:0045444)
0.0 1.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 3.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
0.0 1.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 5.6 GO:0045087 innate immune response(GO:0045087)
0.0 1.4 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 4.0 GO:0008544 epidermis development(GO:0008544)
0.0 0.2 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.7 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.9 GO:0006959 humoral immune response(GO:0006959)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.9 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 1.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.9 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.5 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 1.7 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.3 GO:0042113 B cell activation(GO:0042113)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.1 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.7 GO:0002440 production of molecular mediator of immune response(GO:0002440)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.8 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.4 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.0 0.5 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:1902742 apoptotic process involved in development(GO:1902742)
0.0 0.8 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.7 GO:0051923 sulfation(GO:0051923)
0.0 0.2 GO:0035545 determination of left/right asymmetry in diencephalon(GO:0035462) determination of left/right asymmetry in nervous system(GO:0035545)
0.0 0.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0032196 transposition(GO:0032196)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.1 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:2001286 optomotor response(GO:0071632) caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 2.2 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.2 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.3 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.3 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 2.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.4 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.1 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.3 GO:0050670 regulation of mononuclear cell proliferation(GO:0032944) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.0 28.2 GO:0006508 proteolysis(GO:0006508)
0.0 0.1 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 2.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 8.2 GO:0006412 translation(GO:0006412)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0051101 histone H3-K79 methylation(GO:0034729) regulation of DNA binding(GO:0051101) regulation of transcription regulatory region DNA binding(GO:2000677)
0.0 0.1 GO:0021982 pineal gland development(GO:0021982)
0.0 1.2 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.0 GO:0060039 pericardium development(GO:0060039) visceral serous pericardium development(GO:0061032)
0.0 1.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:2000826 regulation of heart morphogenesis(GO:2000826)
0.0 0.3 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.5 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.0 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 1.0 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 1.5 GO:0055123 digestive system development(GO:0055123)
0.0 0.1 GO:1901071 glucosamine-containing compound metabolic process(GO:1901071)
0.0 0.0 GO:1901052 sarcosine metabolic process(GO:1901052)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.9 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 0.3 GO:0048599 oocyte development(GO:0048599)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.3 GO:0048925 sensory system development(GO:0048880) lateral line system development(GO:0048925)
0.0 2.5 GO:0006955 immune response(GO:0006955)
0.0 0.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0008406 gonad development(GO:0008406)
0.0 2.2 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.1 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0031570 DNA integrity checkpoint(GO:0031570)
0.0 0.4 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.4 GO:0098542 defense response to other organism(GO:0098542)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.2 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.1 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.1 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579)
0.0 2.1 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 1.7 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.3 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.2 GO:0015780 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.1 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.4 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 0.0 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.2 GO:0003094 glomerular filtration(GO:0003094)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.9 2.7 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.9 2.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.7 8.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 1.0 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.3 1.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.5 GO:0097433 dense body(GO:0097433)
0.3 5.8 GO:0030057 desmosome(GO:0030057)
0.3 1.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 1.4 GO:0032433 filopodium tip(GO:0032433)
0.3 1.0 GO:0019815 B cell receptor complex(GO:0019815)
0.2 0.7 GO:0005948 acetolactate synthase complex(GO:0005948)
0.2 1.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 0.9 GO:0043073 germ cell nucleus(GO:0043073)
0.2 1.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 4.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.5 GO:0000796 condensin complex(GO:0000796)
0.2 4.9 GO:0005839 proteasome core complex(GO:0005839)
0.2 0.7 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 1.9 GO:0045095 keratin filament(GO:0045095)
0.2 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 18.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.7 GO:0034362 mature chylomicron(GO:0034359) low-density lipoprotein particle(GO:0034362)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.7 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.8 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 13.3 GO:0005882 intermediate filament(GO:0005882)
0.1 1.1 GO:0032797 SMN complex(GO:0032797)
0.1 8.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0008091 spectrin(GO:0008091)
0.1 0.9 GO:0000439 core TFIIH complex(GO:0000439)
0.1 2.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.4 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 1.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 1.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 2.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.4 GO:0070187 telosome(GO:0070187)
0.1 0.4 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.1 0.4 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.8 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.6 GO:0071256 translocon complex(GO:0071256)
0.1 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 1.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 3.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 3.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.3 GO:0017177 glucosidase II complex(GO:0017177)
0.1 7.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.4 GO:0030686 90S preribosome(GO:0030686)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.3 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.2 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.2 GO:0000801 central element(GO:0000801)
0.1 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 1.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 4.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 4.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 4.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 2.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 1.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 8.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0030428 cell septum(GO:0030428)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 39.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0016234 inclusion body(GO:0016234) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.8 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.6 GO:0005840 ribosome(GO:0005840)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.8 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.0 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 3.8 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 0.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0070822 Sin3-type complex(GO:0070822)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0034185 apolipoprotein binding(GO:0034185)
1.1 5.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.6 1.9 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5 1.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 5.2 GO:0035804 structural constituent of egg coat(GO:0035804)
0.4 1.3 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.4 2.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.4 1.6 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.4 2.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.4 2.0 GO:0009374 biotin binding(GO:0009374)
0.4 3.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 1.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.4 2.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 1.0 GO:0001729 ceramide kinase activity(GO:0001729)
0.3 1.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.5 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 1.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 0.9 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 3.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 1.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.3 0.8 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 1.3 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3 0.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.7 GO:1901612 cardiolipin binding(GO:1901612)
0.2 0.7 GO:0003984 acetolactate synthase activity(GO:0003984)
0.2 1.9 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 1.1 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 2.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 1.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 0.8 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.7 GO:0008887 glycerate kinase activity(GO:0008887)
0.2 1.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 2.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 0.4 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.2 0.9 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.2 1.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 0.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.7 GO:0051916 C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.2 3.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 3.1 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 0.5 GO:0052725 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.2 0.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 1.6 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 2.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.2 0.9 GO:0017040 ceramidase activity(GO:0017040)
0.2 17.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 0.6 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.6 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.7 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 30.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.7 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 1.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.7 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.1 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.2 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE receptor activity(GO:0019767)
0.1 1.3 GO:0004568 chitinase activity(GO:0004568)
0.1 0.6 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.9 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.2 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.6 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 2.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.5 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.2 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 2.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.9 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.8 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.6 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0005549 odorant binding(GO:0005549)
0.1 4.5 GO:0043022 ribosome binding(GO:0043022)
0.1 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 3.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 11.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.3 GO:0005123 death receptor binding(GO:0005123)
0.1 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.8 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 3.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.6 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.3 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.9 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 2.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.9 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 3.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.3 GO:0001096 RNA polymerase II basal transcription factor binding(GO:0001091) TFIIF-class transcription factor binding(GO:0001096)
0.1 0.3 GO:0008026 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 3.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 3.1 GO:0005178 integrin binding(GO:0005178)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 10.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.2 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.1 0.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.2 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.5 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 0.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 4.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.1 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 3.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.8 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 7.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.3 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 4.7 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 4.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 11.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 1.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.9 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 1.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 1.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.8 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.9 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 4.1 GO:0004175 endopeptidase activity(GO:0004175)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.0 0.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0051371 actinin binding(GO:0042805) muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0051765 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0010853 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 1.1 GO:0009055 electron carrier activity(GO:0009055)
0.0 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.6 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 1.4 GO:0042802 identical protein binding(GO:0042802)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.4 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 34.3 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.8 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.4 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 2.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 2.1 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0019239 deaminase activity(GO:0019239)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.3 7.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 1.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 3.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.3 PID ENDOTHELIN PATHWAY Endothelins
0.1 0.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.4 PID AURORA B PATHWAY Aurora B signaling
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 0.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.7 PID ATR PATHWAY ATR signaling pathway
0.1 2.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5 4.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 2.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 1.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 2.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 4.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 4.2 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 1.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 11.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.5 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.6 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 2.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 4.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway