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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for AACGGAA

Z-value: 0.24

Motif logo

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miRNA associated with seed AACGGAA

NamemiRBASE accession
mmu-miR-191-5p
MIMAT0000221

Activity profile of AACGGAA motif

Sorted Z-values of AACGGAA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AACGGAA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrX_-_141749704 1.30 ENSMUST00000041317.3
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr2_+_167530835 1.22 ENSMUST00000070642.4
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr5_+_3393893 1.20 ENSMUST00000165117.8
ENSMUST00000197385.2
Cdk6
cyclin-dependent kinase 6
chr15_-_73056713 1.07 ENSMUST00000044113.12
Ago2
argonaute RISC catalytic subunit 2
chr4_+_106418224 0.99 ENSMUST00000047973.4
Dhcr24
24-dehydrocholesterol reductase
chr1_-_64776890 0.93 ENSMUST00000116133.4
ENSMUST00000063982.7
Fzd5
frizzled class receptor 5
chr15_+_58761057 0.73 ENSMUST00000036904.7
Rnf139
ring finger protein 139
chr4_-_19708910 0.60 ENSMUST00000108246.9
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr4_+_139302009 0.54 ENSMUST00000174078.2
Iffo2
intermediate filament family orphan 2
chr6_-_99243455 0.45 ENSMUST00000113326.9
Foxp1
forkhead box P1
chr17_+_73225292 0.45 ENSMUST00000024857.14
Lbh
limb-bud and heart
chr14_-_25769457 0.42 ENSMUST00000069180.8
Zcchc24
zinc finger, CCHC domain containing 24
chr18_+_31892933 0.42 ENSMUST00000115808.4
Ammecr1l
AMME chromosomal region gene 1-like
chr4_+_128548479 0.41 ENSMUST00000030588.13
ENSMUST00000136377.8
Phc2
polyhomeotic 2
chr11_-_33153587 0.37 ENSMUST00000037746.8
Tlx3
T cell leukemia, homeobox 3
chr5_+_123280250 0.31 ENSMUST00000174836.8
ENSMUST00000163030.9
Setd1b
SET domain containing 1B
chrX_-_13712746 0.30 ENSMUST00000115436.9
ENSMUST00000033321.11
ENSMUST00000115438.10
Cask
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr10_-_115087309 0.21 ENSMUST00000020339.10
Tbc1d15
TBC1 domain family, member 15
chr8_-_89770790 0.19 ENSMUST00000034090.8
Sall1
spalt like transcription factor 1
chr17_-_32607859 0.17 ENSMUST00000087703.12
ENSMUST00000170603.3
Wiz
widely-interspaced zinc finger motifs
chr4_+_97665843 0.12 ENSMUST00000075448.13
ENSMUST00000092532.13
Nfia
nuclear factor I/A
chr11_+_87959067 0.05 ENSMUST00000018521.11
Vezf1
vascular endothelial zinc finger 1
chr19_+_3817396 0.04 ENSMUST00000052699.13
ENSMUST00000113974.11
ENSMUST00000113972.9
ENSMUST00000113973.8
ENSMUST00000113977.9
ENSMUST00000113968.9
Kmt5b
lysine methyltransferase 5B
chr12_+_35097179 0.02 ENSMUST00000163677.3
ENSMUST00000048519.17
Snx13
sorting nexin 13
chr5_+_30971915 0.02 ENSMUST00000031058.15
Mapre3
microtubule-associated protein, RP/EB family, member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.3 0.9 GO:0060715 Spemann organizer formation(GO:0060061) syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 1.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 1.2 GO:0002432 granuloma formation(GO:0002432)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.4 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.0 1.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.4 1.2 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.1 1.1 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.0 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0098808 mRNA cap binding(GO:0098808)
0.3 1.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation