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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for AAGGUGC

Z-value: 0.34

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miRNA associated with seed AAGGUGC

NamemiRBASE accession
mmu-miR-18a-5p
MIMAT0000528
mmu-miR-18b-5p
MIMAT0004858

Activity profile of AAGGUGC motif

Sorted Z-values of AAGGUGC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGGUGC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_41640757 1.38 ENSMUST00000021794.14
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr13_-_111945499 1.31 ENSMUST00000109267.9
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr16_-_92622972 0.96 ENSMUST00000023673.14
Runx1
runt related transcription factor 1
chr3_+_60408600 0.92 ENSMUST00000099087.8
Mbnl1
muscleblind like splicing factor 1
chr2_-_34803988 0.89 ENSMUST00000028232.7
ENSMUST00000202907.2
Phf19
PHD finger protein 19
chr5_+_137517140 0.88 ENSMUST00000031727.10
Gigyf1
GRB10 interacting GYF protein 1
chr12_-_15866763 0.80 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
Trib2
tribbles pseudokinase 2
chr10_-_18891095 0.79 ENSMUST00000019997.11
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr5_-_73413888 0.75 ENSMUST00000101127.12
Fryl
FRY like transcription coactivator
chr8_-_35962641 0.74 ENSMUST00000033927.8
Eri1
exoribonuclease 1
chr16_-_50252703 0.72 ENSMUST00000066037.13
ENSMUST00000089399.11
ENSMUST00000089404.10
ENSMUST00000138166.8
Bbx
bobby sox HMG box containing
chr2_+_117942357 0.71 ENSMUST00000039559.9
Thbs1
thrombospondin 1
chr12_+_73948143 0.69 ENSMUST00000110461.8
Hif1a
hypoxia inducible factor 1, alpha subunit
chr2_+_163916042 0.69 ENSMUST00000018353.14
Stk4
serine/threonine kinase 4
chr6_+_119213468 0.66 ENSMUST00000238905.2
ENSMUST00000037434.13
Cacna2d4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr8_-_121316043 0.64 ENSMUST00000034278.6
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr13_+_110039620 0.62 ENSMUST00000120664.8
Pde4d
phosphodiesterase 4D, cAMP specific
chr10_+_4561974 0.60 ENSMUST00000105590.8
ENSMUST00000067086.14
Esr1
estrogen receptor 1 (alpha)
chr5_+_97145533 0.60 ENSMUST00000112974.6
ENSMUST00000035635.10
Bmp2k
BMP2 inducible kinase
chr3_-_59251573 0.57 ENSMUST00000193455.6
ENSMUST00000039419.12
ENSMUST00000195983.2
Igsf10
immunoglobulin superfamily, member 10
chr13_-_49024583 0.57 ENSMUST00000035540.9
Phf2
PHD finger protein 2
chr6_+_140568366 0.49 ENSMUST00000032359.15
Aebp2
AE binding protein 2
chr9_+_30941924 0.47 ENSMUST00000216649.2
ENSMUST00000115222.10
Zbtb44
zinc finger and BTB domain containing 44
chr16_+_24212284 0.47 ENSMUST00000038053.14
Lpp
LIM domain containing preferred translocation partner in lipoma
chr7_+_100757940 0.45 ENSMUST00000032931.9
Fchsd2
FCH and double SH3 domains 2
chr1_-_97589675 0.45 ENSMUST00000053033.14
ENSMUST00000149927.2
Macir
macrophage immunometabolism regulator
chr1_+_170472092 0.44 ENSMUST00000046792.9
Olfml2b
olfactomedin-like 2B
chr16_-_21982049 0.41 ENSMUST00000100052.11
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_134487928 0.41 ENSMUST00000112198.3
Kdm5b
lysine (K)-specific demethylase 5B
chr4_+_65042411 0.41 ENSMUST00000084501.4
Pappa
pregnancy-associated plasma protein A
chr15_+_80595486 0.39 ENSMUST00000067689.9
Tnrc6b
trinucleotide repeat containing 6b
chrX_-_107877909 0.38 ENSMUST00000101283.4
ENSMUST00000150434.8
Brwd3
bromodomain and WD repeat domain containing 3
chr8_-_85414528 0.35 ENSMUST00000001975.6
Nacc1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr12_+_111005768 0.34 ENSMUST00000084968.14
Rcor1
REST corepressor 1
chr7_-_115637970 0.34 ENSMUST00000166877.8
Sox6
SRY (sex determining region Y)-box 6
chr2_-_24809583 0.33 ENSMUST00000046227.12
ENSMUST00000114432.9
ENSMUST00000091348.11
ENSMUST00000102938.10
ENSMUST00000150379.2
ENSMUST00000152161.8
ENSMUST00000147147.8
Ehmt1
euchromatic histone methyltransferase 1
chr1_-_160958998 0.33 ENSMUST00000111611.8
Klhl20
kelch-like 20
chr10_+_40225272 0.33 ENSMUST00000044672.11
ENSMUST00000095743.4
Cdk19
cyclin-dependent kinase 19
chr3_-_9675130 0.33 ENSMUST00000041124.13
Zfp704
zinc finger protein 704
chr19_+_53128861 0.32 ENSMUST00000111741.10
Add3
adducin 3 (gamma)
chr5_+_75735576 0.31 ENSMUST00000144270.8
ENSMUST00000005815.7
Kit
KIT proto-oncogene receptor tyrosine kinase
chr16_+_93885775 0.30 ENSMUST00000072182.9
Sim2
single-minded family bHLH transcription factor 2
chr15_+_73594965 0.30 ENSMUST00000165541.8
ENSMUST00000167582.8
Ptp4a3
protein tyrosine phosphatase 4a3
chr16_+_43960183 0.28 ENSMUST00000159514.8
ENSMUST00000161326.8
ENSMUST00000063520.15
ENSMUST00000063542.8
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr15_-_76554065 0.27 ENSMUST00000037824.6
Foxh1
forkhead box H1
chr2_+_72115981 0.26 ENSMUST00000090824.12
ENSMUST00000135469.8
Map3k20
mitogen-activated protein kinase kinase kinase 20
chr2_+_112097087 0.26 ENSMUST00000110987.9
ENSMUST00000028549.14
Slc12a6
solute carrier family 12, member 6
chr1_-_165830160 0.25 ENSMUST00000111429.11
ENSMUST00000176800.2
ENSMUST00000177358.8
Pou2f1
POU domain, class 2, transcription factor 1
chr1_-_63153675 0.22 ENSMUST00000097718.9
Ino80d
INO80 complex subunit D
chr11_-_94568228 0.22 ENSMUST00000116349.9
Xylt2
xylosyltransferase II
chr3_+_96604390 0.22 ENSMUST00000162778.3
ENSMUST00000064900.16
Pias3
protein inhibitor of activated STAT 3
chr12_+_3476857 0.21 ENSMUST00000111215.10
ENSMUST00000092003.12
ENSMUST00000144247.9
ENSMUST00000153102.9
Asxl2
ASXL transcriptional regulator 2
chr5_+_23639432 0.21 ENSMUST00000094962.9
ENSMUST00000115128.8
Kmt2e
lysine (K)-specific methyltransferase 2E
chr4_-_133746138 0.21 ENSMUST00000051674.3
Lin28a
lin-28 homolog A (C. elegans)
chr10_+_13428638 0.20 ENSMUST00000019944.9
Adat2
adenosine deaminase, tRNA-specific 2
chr6_-_134769558 0.20 ENSMUST00000100857.10
Dusp16
dual specificity phosphatase 16
chr11_-_95956176 0.19 ENSMUST00000100528.5
Ube2z
ubiquitin-conjugating enzyme E2Z
chr12_-_91556761 0.18 ENSMUST00000021345.14
Gtf2a1
general transcription factor II A, 1
chr1_-_165762469 0.18 ENSMUST00000069609.12
ENSMUST00000111427.9
ENSMUST00000111426.11
Pou2f1
POU domain, class 2, transcription factor 1
chr10_-_53252210 0.18 ENSMUST00000095691.7
Cep85l
centrosomal protein 85-like
chr6_-_72876882 0.18 ENSMUST00000068697.11
Kcmf1
potassium channel modulatory factor 1
chr11_+_29323618 0.17 ENSMUST00000040182.13
ENSMUST00000109477.2
Ccdc88a
coiled coil domain containing 88A
chr11_+_77576981 0.16 ENSMUST00000100802.11
ENSMUST00000181023.2
Nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr8_-_95328348 0.16 ENSMUST00000212547.2
ENSMUST00000212507.2
ENSMUST00000034226.8
Psme3ip1
proteasome activator subunit 3 interacting protein 1
chr3_-_101017594 0.15 ENSMUST00000102694.4
Ptgfrn
prostaglandin F2 receptor negative regulator
chr4_+_106173384 0.15 ENSMUST00000165709.8
ENSMUST00000094933.5
Usp24
ubiquitin specific peptidase 24
chr16_+_42727926 0.14 ENSMUST00000151244.8
ENSMUST00000114694.9
Zbtb20
zinc finger and BTB domain containing 20
chr19_+_32734884 0.14 ENSMUST00000013807.8
Pten
phosphatase and tensin homolog
chr11_-_29464998 0.14 ENSMUST00000133103.2
ENSMUST00000039900.4
Prorsd1
prolyl-tRNA synthetase domain containing 1
chr10_+_80330669 0.14 ENSMUST00000051773.9
Onecut3
one cut domain, family member 3
chr3_+_88049633 0.12 ENSMUST00000001455.13
ENSMUST00000119251.8
Mef2d
myocyte enhancer factor 2D
chr3_+_97920819 0.11 ENSMUST00000079812.8
Notch2
notch 2
chr10_+_87695117 0.10 ENSMUST00000105300.9
Igf1
insulin-like growth factor 1
chr10_+_43354807 0.09 ENSMUST00000167488.9
Bend3
BEN domain containing 3
chr3_+_105359641 0.08 ENSMUST00000098761.10
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr7_-_28947882 0.08 ENSMUST00000032808.6
2200002D01Rik
RIKEN cDNA 2200002D01 gene
chr11_+_4207557 0.08 ENSMUST00000066283.12
Lif
leukemia inhibitory factor
chr3_-_31023547 0.08 ENSMUST00000064718.12
ENSMUST00000177992.8
ENSMUST00000129817.9
ENSMUST00000168645.8
ENSMUST00000108255.8
ENSMUST00000099163.5
Phc3
polyhomeotic 3
chr3_-_146518706 0.07 ENSMUST00000102515.10
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr18_-_39623698 0.06 ENSMUST00000115567.8
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr2_+_19450443 0.06 ENSMUST00000028068.3
Ptf1a
pancreas specific transcription factor, 1a
chr6_+_52690714 0.06 ENSMUST00000080723.11
ENSMUST00000149588.8
Tax1bp1
Tax1 (human T cell leukemia virus type I) binding protein 1
chr9_+_118755521 0.06 ENSMUST00000073109.12
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr9_-_14292453 0.05 ENSMUST00000167549.2
Endod1
endonuclease domain containing 1
chr1_+_88998115 0.04 ENSMUST00000066279.11
Sh3bp4
SH3-domain binding protein 4
chr13_-_93636224 0.04 ENSMUST00000220513.2
ENSMUST00000065537.9
Jmy
junction-mediating and regulatory protein
chr1_+_74448535 0.04 ENSMUST00000027366.13
Vil1
villin 1
chr17_-_30107544 0.04 ENSMUST00000171691.9
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr19_-_59932079 0.03 ENSMUST00000171986.8
Rab11fip2
RAB11 family interacting protein 2 (class I)
chr1_-_135513443 0.03 ENSMUST00000067414.13
Nav1
neuron navigator 1
chr7_-_126101555 0.02 ENSMUST00000167759.8
Atxn2l
ataxin 2-like
chr13_-_46118433 0.01 ENSMUST00000167708.4
ENSMUST00000091628.11
ENSMUST00000180110.9
Atxn1
ataxin 1
chr5_-_69749617 0.01 ENSMUST00000173927.8
ENSMUST00000120789.8
ENSMUST00000031117.13
Gnpda2
glucosamine-6-phosphate deaminase 2
chr1_-_161704224 0.00 ENSMUST00000048377.11
Suco
SUN domain containing ossification factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.3 0.8 GO:0002632 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 1.0 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 0.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
0.2 0.7 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 0.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.6 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.4 GO:2000864 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.1 0.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.7 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.3 GO:1904349 positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.1 0.4 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 1.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:1990705 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.7 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.9 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0000811 GINS complex(GO:0000811)
0.1 0.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 0.7 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 0.7 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.3 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.3 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter