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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for AAGUGCU

Z-value: 0.65

Motif logo

miRNA associated with seed AAGUGCU

NamemiRBASE accession
MIMAT0000368
MIMAT0000372
MIMAT0000373
MIMAT0000380
MIMAT0003374
MIMAT0003377

Activity profile of AAGUGCU motif

Sorted Z-values of AAGUGCU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGUGCU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_135899678 4.65 ENSMUST00000061721.6
E2F transcription factor 2
chr2_+_127178072 4.53 ENSMUST00000028846.7
dual specificity phosphatase 2
chr1_-_69724939 3.61 ENSMUST00000027146.9
IKAROS family zinc finger 2
chr16_+_57173456 3.51 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr4_+_11156411 3.33 ENSMUST00000029865.4
transformation related protein 53 inducible nuclear protein 1
chr5_+_3393893 3.09 ENSMUST00000165117.8
ENSMUST00000197385.2
cyclin-dependent kinase 6
chr5_-_136596299 2.98 ENSMUST00000004097.16
cut-like homeobox 1
chr13_-_111945499 2.97 ENSMUST00000109267.9
mitogen-activated protein kinase kinase kinase 1
chr17_-_32074754 2.88 ENSMUST00000024839.6
salt inducible kinase 1
chr5_-_21156766 2.80 ENSMUST00000036489.10
round spermatid basic protein 1-like
chr2_-_131871725 2.74 ENSMUST00000028814.15
Ras association (RalGDS/AF-6) domain family member 2
chr16_-_23807602 2.68 ENSMUST00000023151.6
B cell leukemia/lymphoma 6
chr5_+_77413282 2.67 ENSMUST00000080359.12
RE1-silencing transcription factor
chr5_+_64960705 2.58 ENSMUST00000165536.8
Kruppel-like factor 3 (basic)
chr1_-_45964730 2.58 ENSMUST00000027137.11
solute carrier family 40 (iron-regulated transporter), member 1
chr3_+_96465265 2.57 ENSMUST00000074519.13
ENSMUST00000049093.8
thioredoxin interacting protein
chr11_-_103158190 2.56 ENSMUST00000021324.3
mitogen-activated protein kinase kinase kinase 14
chr10_+_96452860 2.37 ENSMUST00000038377.9
BTG anti-proliferation factor 1
chr11_-_5211558 2.34 ENSMUST00000020662.15
kringle containing transmembrane protein 1
chr12_-_118265103 2.22 ENSMUST00000222314.2
ENSMUST00000026367.11
trans-acting transcription factor 4
chr9_-_44792575 2.22 ENSMUST00000114689.8
ENSMUST00000002095.11
ENSMUST00000128768.3
lysine (K)-specific methyltransferase 2A
chr2_+_4405769 2.10 ENSMUST00000075767.14
FERM domain containing 4A
chr3_-_27208010 2.09 ENSMUST00000108300.8
ENSMUST00000108298.9
ect2 oncogene
chr13_+_111822712 2.08 ENSMUST00000109272.9
MIER family member 3
chr10_-_128540847 1.98 ENSMUST00000026415.9
ENSMUST00000026416.15
cyclin-dependent kinase 2
chr12_+_71062733 1.97 ENSMUST00000046305.12
AT rich interactive domain 4A (RBP1-like)
chr5_-_44383943 1.96 ENSMUST00000055128.12
transmembrane anterior posterior transformation 1
chr5_+_73071607 1.95 ENSMUST00000144843.8
SLAIN motif family, member 2
chr3_+_95566082 1.95 ENSMUST00000037947.15
ENSMUST00000178686.2
myeloid cell leukemia sequence 1
chr12_-_107969853 1.91 ENSMUST00000066060.11
B cell leukemia/lymphoma 11B
chr6_-_99243455 1.90 ENSMUST00000113326.9
forkhead box P1
chr5_+_137517140 1.89 ENSMUST00000031727.10
GRB10 interacting GYF protein 1
chr3_+_60408600 1.86 ENSMUST00000099087.8
muscleblind like splicing factor 1
chr9_+_7764042 1.84 ENSMUST00000052865.16
transmembrane protein 123
chr2_-_104647041 1.83 ENSMUST00000117237.2
ENSMUST00000231375.2
glutamine and serine rich 1
chrX_-_50294652 1.78 ENSMUST00000114875.8
muscleblind like splicing factor 3
chr19_+_40819682 1.75 ENSMUST00000025983.13
ENSMUST00000119316.2
cyclin J
chr15_-_57998443 1.74 ENSMUST00000038194.5
ATPase family, AAA domain containing 2
chr4_-_126362372 1.73 ENSMUST00000097888.10
ENSMUST00000239399.2
argonaute RISC catalytic subunit 1
chr2_-_153083322 1.72 ENSMUST00000056924.14
pleiomorphic adenoma gene-like 2
chr2_-_19002932 1.69 ENSMUST00000006912.12
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr8_-_127320685 1.68 ENSMUST00000054960.9
interferon regulatory factor 2 binding protein 2
chr12_-_79343040 1.67 ENSMUST00000218377.2
ENSMUST00000021547.8
zinc finger, FYVE domain containing 26
chr13_-_117162041 1.63 ENSMUST00000022239.8
poly (ADP-ribose) polymerase family, member 8
chr2_+_72306503 1.62 ENSMUST00000102691.11
ENSMUST00000157019.2
cell division cycle associated 7
chr11_+_97554192 1.61 ENSMUST00000044730.12
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
chr3_+_130904000 1.55 ENSMUST00000029611.14
ENSMUST00000106341.9
ENSMUST00000066849.13
lymphoid enhancer binding factor 1
chr19_-_14575395 1.49 ENSMUST00000052011.15
ENSMUST00000167776.3
transducin-like enhancer of split 4
chr11_-_49603501 1.48 ENSMUST00000020624.7
ENSMUST00000145353.8
CCR4-NOT transcription complex, subunit 6
chr10_+_53473032 1.47 ENSMUST00000020004.8
anti-silencing function 1A histone chaperone
chr6_-_127128007 1.46 ENSMUST00000000188.12
cyclin D2
chr10_+_70080913 1.44 ENSMUST00000046807.7
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr1_+_131935342 1.41 ENSMUST00000086556.12
ELK4, member of ETS oncogene family
chr2_-_156848923 1.41 ENSMUST00000146413.8
ENSMUST00000103129.9
ENSMUST00000103130.8
DSN1 homolog, MIS12 kinetochore complex component
chr9_-_116004265 1.38 ENSMUST00000061101.12
transforming growth factor, beta receptor II
chr5_-_96309849 1.35 ENSMUST00000155901.8
CCR4-NOT transcription complex, subunit 6-like
chr8_-_35962641 1.34 ENSMUST00000033927.8
exoribonuclease 1
chr4_-_3938352 1.34 ENSMUST00000003369.10
pleiomorphic adenoma gene 1
chr11_-_103303480 1.34 ENSMUST00000041272.10
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr4_+_97665843 1.33 ENSMUST00000075448.13
ENSMUST00000092532.13
nuclear factor I/A
chr16_+_36832119 1.32 ENSMUST00000071452.12
ENSMUST00000054034.7
polymerase (DNA directed), theta
chr10_-_128727542 1.32 ENSMUST00000026408.7
growth differentiation factor 11
chr9_+_30941924 1.31 ENSMUST00000216649.2
ENSMUST00000115222.10
zinc finger and BTB domain containing 44
chr3_+_28317354 1.27 ENSMUST00000159236.9
TRAF2 and NCK interacting kinase
chr5_+_147367237 1.27 ENSMUST00000176600.8
PAN3 poly(A) specific ribonuclease subunit
chr8_+_23349543 1.26 ENSMUST00000238975.2
ENSMUST00000110696.8
ENSMUST00000044331.7
K(lysine) acetyltransferase 6A
chr1_-_9770434 1.25 ENSMUST00000088658.11
myeloblastosis oncogene-like 1
chr19_+_41471067 1.24 ENSMUST00000067795.13
ligand dependent nuclear receptor corepressor
chr2_-_157046386 1.24 ENSMUST00000029170.8
RB transcriptional corepressor like 1
chr6_+_91955820 1.22 ENSMUST00000089334.9
FYVE, RhoGEF and PH domain containing 5
chr13_+_47196975 1.21 ENSMUST00000037025.16
ENSMUST00000143868.2
lysine (K)-specific demethylase 1B
chr4_-_135749032 1.21 ENSMUST00000030427.6
elongin A
chrX_+_158038778 1.20 ENSMUST00000126686.8
ENSMUST00000033671.13
ribosomal protein S6 kinase polypeptide 3
chr7_-_63588610 1.20 ENSMUST00000063694.10
Kruppel-like factor 13
chr11_-_51891259 1.19 ENSMUST00000020657.13
ubiquitin-conjugating enzyme E2B
chr7_-_67022520 1.19 ENSMUST00000156690.8
ENSMUST00000107476.8
ENSMUST00000076325.12
ENSMUST00000032776.15
ENSMUST00000133074.2
myocyte enhancer factor 2A
chr15_-_66985760 1.18 ENSMUST00000092640.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr8_+_85753452 1.18 ENSMUST00000047281.10
telomerase RNA component interacting RNase
chr9_+_121946321 1.16 ENSMUST00000119215.9
ENSMUST00000146832.8
ENSMUST00000118886.9
ENSMUST00000120173.9
ENSMUST00000139181.2
SNF related kinase
chr11_-_46203047 1.15 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr3_+_65435825 1.14 ENSMUST00000047906.10
TCDD-inducible poly(ADP-ribose) polymerase
chr6_-_83418656 1.13 ENSMUST00000089622.11
tet methylcytosine dioxygenase 3
chr17_-_88372671 1.11 ENSMUST00000235112.2
ENSMUST00000005504.15
F-box protein 11
chr17_-_52139693 1.10 ENSMUST00000144331.8
special AT-rich sequence binding protein 1
chr14_+_103887644 1.09 ENSMUST00000069443.14
SLAIN motif family, member 1
chr11_-_115405200 1.09 ENSMUST00000021083.7
Jupiter microtubule associated homolog 1
chr18_+_3507917 1.05 ENSMUST00000025075.3
BMP and activin membrane-bound inhibitor
chr18_+_89215543 1.05 ENSMUST00000037142.13
CD226 antigen
chr15_+_95688712 1.05 ENSMUST00000071874.8
anoctamin 6
chr11_-_72302520 1.04 ENSMUST00000108500.8
ENSMUST00000050226.7
smoothelin-like 2
chr19_-_30526916 1.03 ENSMUST00000025803.9
dickkopf WNT signaling pathway inhibitor 1
chr15_+_6737853 1.03 ENSMUST00000061656.8
RPTOR independent companion of MTOR, complex 2
chr17_-_90217868 1.01 ENSMUST00000086423.6
predicted pseudogene 10184
chr1_+_6284823 1.00 ENSMUST00000027040.13
RB1-inducible coiled-coil 1
chr2_-_6889783 1.00 ENSMUST00000170438.8
ENSMUST00000114924.10
ENSMUST00000114934.11
CUGBP, Elav-like family member 2
chrX_-_77627486 1.00 ENSMUST00000114025.8
ENSMUST00000134602.8
ENSMUST00000114024.9
proline rich Gla (G-carboxyglutamic acid) 1
chr15_+_100513230 0.99 ENSMUST00000000356.10
DAZ associated protein 2
chr11_-_4544751 0.97 ENSMUST00000109943.10
myotubularin related protein 3
chr16_-_31898088 0.97 ENSMUST00000023467.9
p21 (RAC1) activated kinase 2
chr4_+_41135730 0.97 ENSMUST00000040008.4
ubiquitin-conjugating enzyme E2R 2
chr6_+_120643323 0.94 ENSMUST00000112686.8
CECR2, histone acetyl-lysine reader
chr1_-_74163575 0.94 ENSMUST00000169786.8
ENSMUST00000212888.2
ENSMUST00000191104.7
tensin 1
chr5_-_143717970 0.94 ENSMUST00000053287.6
ubiquitin specific peptidase 42
chr10_+_42554888 0.94 ENSMUST00000040718.6
osteopetrosis associated transmembrane protein 1
chr12_-_65010124 0.94 ENSMUST00000021331.9
kelch-like 28
chr13_+_83652352 0.91 ENSMUST00000198916.5
ENSMUST00000200123.5
ENSMUST00000005722.14
ENSMUST00000163888.8
myocyte enhancer factor 2C
chr10_+_110581293 0.89 ENSMUST00000174857.8
ENSMUST00000073781.12
ENSMUST00000173471.8
ENSMUST00000173634.2
E2F transcription factor 7
chr4_+_59805829 0.89 ENSMUST00000030080.7
sorting nexin family member 30
chr1_-_165287999 0.88 ENSMUST00000027856.13
DDB1 and CUL4 associated factor 6
chr16_-_92622972 0.88 ENSMUST00000023673.14
runt related transcription factor 1
chr13_+_45660905 0.88 ENSMUST00000000260.13
guanosine monophosphate reductase
chrX_-_47543029 0.88 ENSMUST00000114958.8
E74-like factor 4 (ets domain transcription factor)
chr4_-_133615075 0.87 ENSMUST00000003741.16
ENSMUST00000105894.11
ribosomal protein S6 kinase polypeptide 1
chr14_-_103336990 0.86 ENSMUST00000022720.15
ENSMUST00000144141.8
F-box and leucine-rich repeat protein 3
chr6_+_140568366 0.85 ENSMUST00000032359.15
AE binding protein 2
chr2_-_60383647 0.85 ENSMUST00000112525.5
phospholipase A2 receptor 1
chr1_-_180524587 0.83 ENSMUST00000027778.8
Mix1 homeobox-like 1 (Xenopus laevis)
chr4_-_86530245 0.83 ENSMUST00000125481.3
ENSMUST00000070607.9
HAUS augmin-like complex, subunit 6
chr4_+_32982981 0.82 ENSMUST00000098190.10
ENSMUST00000029946.14
Ras-related GTP binding D
chr13_-_55477535 0.82 ENSMUST00000021941.8
Max dimerization protein 3
chr9_-_59393893 0.82 ENSMUST00000171975.8
ariadne RBR E3 ubiquitin protein ligase 1
chr11_-_104333059 0.80 ENSMUST00000106977.8
ENSMUST00000106972.8
KAT8 regulatory NSL complex subunit 1
chr11_-_34674677 0.80 ENSMUST00000093193.12
ENSMUST00000101365.9
dedicator of cyto-kinesis 2
chr5_-_25703700 0.80 ENSMUST00000173073.8
ENSMUST00000045291.14
ENSMUST00000173174.2
lysine (K)-specific methyltransferase 2C
chr1_-_181039509 0.78 ENSMUST00000162819.9
ENSMUST00000237749.2
WD repeat domain 26
chr17_+_53873964 0.78 ENSMUST00000000724.15
K(lysine) acetyltransferase 2B
chr2_+_127967951 0.77 ENSMUST00000089634.12
ENSMUST00000019281.14
ENSMUST00000110341.9
ENSMUST00000103211.8
ENSMUST00000103210.2
BCL2-like 11 (apoptosis facilitator)
chr17_+_27192135 0.77 ENSMUST00000120016.3
zinc finger and BTB domain containing 9
chr8_-_86281946 0.76 ENSMUST00000034138.7
DnaJ heat shock protein family (Hsp40) member A2
chr18_+_32948436 0.76 ENSMUST00000025237.5
thymic stromal lymphopoietin
chr19_+_53298906 0.75 ENSMUST00000003870.15
MAX interactor 1, dimerization protein
chr18_-_46658957 0.75 ENSMUST00000036226.6
fem 1 homolog c
chr16_+_42727926 0.75 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr1_-_119765343 0.75 ENSMUST00000064091.12
protein tyrosine phosphatase, non-receptor type 4
chr6_-_90787100 0.74 ENSMUST00000101151.10
IQ motif and Sec7 domain 1
chr1_-_80318197 0.73 ENSMUST00000163119.8
cullin 3
chr17_-_48716756 0.71 ENSMUST00000160319.8
ENSMUST00000159535.2
ENSMUST00000078800.13
ENSMUST00000046719.14
ENSMUST00000162460.8
nuclear transcription factor-Y alpha
chr10_-_85752765 0.71 ENSMUST00000037646.9
ENSMUST00000220032.2
PR domain containing 4
chr2_+_16361081 0.71 ENSMUST00000028081.13
plexin domain containing 2
chr4_+_106173384 0.70 ENSMUST00000165709.8
ENSMUST00000094933.5
ubiquitin specific peptidase 24
chr17_+_26934617 0.69 ENSMUST00000062519.14
ENSMUST00000144221.2
ENSMUST00000142539.8
ENSMUST00000151681.2
CREB3 regulatory factor
chr2_-_144112700 0.69 ENSMUST00000110030.10
sorting nexin 5
chr11_+_60428788 0.68 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr4_-_128699838 0.68 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr3_-_100396635 0.67 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr5_-_38719025 0.67 ENSMUST00000005234.13
WD repeat domain 1
chr8_-_27664651 0.67 ENSMUST00000054212.7
ENSMUST00000033878.14
ENSMUST00000209377.2
RAB11 family interacting protein 1 (class I)
chr17_+_25407352 0.66 ENSMUST00000039734.12
unkempt family like zinc finger
chr5_+_139366336 0.65 ENSMUST00000051293.8
G protein-coupled receptor 146
chr13_+_43551851 0.64 ENSMUST00000071926.5
ENSMUST00000222499.2
nucleolar protein 7
chr3_-_144275897 0.63 ENSMUST00000043325.9
heparan sulfate 2-O-sulfotransferase 1
chr19_+_18648088 0.62 ENSMUST00000025632.11
carnosine N-methyltransferase 1
chr13_-_47083194 0.62 ENSMUST00000056978.8
kinesin family member 13A
chr4_-_44167509 0.62 ENSMUST00000098098.9
ring finger protein 38
chr19_-_53378990 0.61 ENSMUST00000025997.7
survival motor neuron domain containing 1
chr13_-_9814407 0.61 ENSMUST00000146059.8
ENSMUST00000110637.8
zinc finger, MYND domain containing 11
chr1_-_119349969 0.61 ENSMUST00000038765.6
inhibin beta-B
chr12_-_100691251 0.60 ENSMUST00000043599.7
ribosomal protein S6 kinase, polypeptide 5
chr18_-_46331877 0.59 ENSMUST00000167364.9
tripartite motif-containing 36
chr7_+_58878490 0.59 ENSMUST00000202945.4
ENSMUST00000107537.5
ubiquitin protein ligase E3A
chr19_+_3817396 0.59 ENSMUST00000052699.13
ENSMUST00000113974.11
ENSMUST00000113972.9
ENSMUST00000113973.8
ENSMUST00000113977.9
ENSMUST00000113968.9
lysine methyltransferase 5B
chr19_+_46490123 0.59 ENSMUST00000026008.9
tripartite motif-containing 8
chr11_+_95304903 0.59 ENSMUST00000107724.9
ENSMUST00000150884.8
ENSMUST00000107722.8
ENSMUST00000127713.2
speckle-type BTB/POZ protein
chr16_-_4377640 0.57 ENSMUST00000005862.9
transcription factor AP4
chr11_+_77576981 0.57 ENSMUST00000100802.11
ENSMUST00000181023.2
nuclear fragile X mental retardation protein interacting protein 2
chr19_+_44551280 0.56 ENSMUST00000040455.5
hypoxia-inducible factor 1, alpha subunit inhibitor
chr2_-_104324745 0.56 ENSMUST00000028600.14
homeodomain interacting protein kinase 3
chr6_-_84570890 0.55 ENSMUST00000168003.9
cytochrome P450, family 26, subfamily b, polypeptide 1
chr8_+_11808349 0.55 ENSMUST00000074856.13
ENSMUST00000098938.9
Rho guanine nucleotide exchange factor (GEF7)
chr11_-_106890307 0.54 ENSMUST00000018506.13
karyopherin (importin) alpha 2
chr6_+_92068361 0.54 ENSMUST00000113460.8
nuclear receptor subfamily 2, group C, member 2
chr11_-_65160767 0.54 ENSMUST00000102635.10
myocardin
chr18_+_70701260 0.53 ENSMUST00000074058.11
ENSMUST00000114946.4
methyl-CpG binding domain protein 2
chr5_-_67585137 0.52 ENSMUST00000169190.5
BEN domain containing 4
chr6_+_141194886 0.52 ENSMUST00000043259.10
phosphodiesterase 3A, cGMP inhibited
chr7_+_144450260 0.51 ENSMUST00000033389.7
ENSMUST00000207229.2
fibroblast growth factor 15
chr2_-_33358513 0.51 ENSMUST00000113156.2
ENSMUST00000028125.12
ENSMUST00000126442.2
zinc finger and BTB domain containing 43
chr6_-_39396691 0.50 ENSMUST00000146785.8
ENSMUST00000114823.8
makorin, ring finger protein, 1
chr8_+_106786190 0.49 ENSMUST00000109308.3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
chr16_+_33201164 0.49 ENSMUST00000165418.9
zinc finger protein 148
chr14_-_57983511 0.48 ENSMUST00000173990.8
ENSMUST00000022531.14
large tumor suppressor 2
chr4_+_15265798 0.48 ENSMUST00000062684.9
transmembrane protein 64
chr9_+_15217548 0.47 ENSMUST00000215124.2
ENSMUST00000164079.9
ENSMUST00000216109.2
TATA-box binding protein associated factor, RNA polymerase I, D
chr2_+_118731860 0.47 ENSMUST00000036578.7
bromo adjacent homology domain containing 1
chr3_+_121746862 0.45 ENSMUST00000037958.14
ENSMUST00000196904.5
Rho GTPase activating protein 29
chr15_-_64184485 0.45 ENSMUST00000177083.8
ENSMUST00000177371.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr3_+_88439616 0.45 ENSMUST00000172699.2
mex3 RNA binding family member A
chr9_-_114393406 0.45 ENSMUST00000111816.3
tripartite motif-containing 71
chr3_+_16237371 0.45 ENSMUST00000108345.9
ENSMUST00000191774.6
ENSMUST00000108346.5
YTH N6-methyladenosine RNA binding protein 3
chr19_+_25483070 0.45 ENSMUST00000087525.5
doublesex and mab-3 related transcription factor 1
chr18_+_32296126 0.44 ENSMUST00000096575.5
mitogen-activated protein kinase kinase kinase 2
chr16_-_97723753 0.44 ENSMUST00000170757.3
C2 calcium-dependent domain containing 2
chr18_-_61533434 0.44 ENSMUST00000063307.6
ENSMUST00000075299.13
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
chr6_-_116605914 0.44 ENSMUST00000079749.6
zinc finger protein 422
chr10_-_118705029 0.43 ENSMUST00000004281.10
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr11_+_4207557 0.42 ENSMUST00000066283.12
leukemia inhibitory factor
chr13_+_14238361 0.42 ENSMUST00000129488.8
ENSMUST00000110536.8
ENSMUST00000110534.8
ENSMUST00000039538.15
ENSMUST00000110533.2
AT rich interactive domain 4B (RBP1-like)
chr11_-_86884507 0.42 ENSMUST00000018571.5
yippee like 2
chr13_-_46118433 0.42 ENSMUST00000167708.4
ENSMUST00000091628.11
ENSMUST00000180110.9
ataxin 1
chr11_+_104498824 0.42 ENSMUST00000021028.5
integrin beta 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
1.0 3.1 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.9 2.6 GO:0070839 divalent metal ion export(GO:0070839)
0.8 6.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.7 2.7 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.7 2.7 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.6 1.9 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.6 1.7 GO:0034378 chylomicron assembly(GO:0034378)
0.6 2.2 GO:2001025 positive regulation of response to drug(GO:2001025)
0.5 1.6 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.5 1.0 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.5 2.0 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.4 0.9 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.4 1.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.4 1.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.4 1.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895)
0.4 2.9 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.4 1.4 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.3 3.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 1.0 GO:0097045 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.3 4.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 1.0 GO:0061723 glycophagy(GO:0061723)
0.3 0.8 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.2 3.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 1.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 1.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.2 0.9 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 1.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.6 GO:1990164 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.2 0.6 GO:0035037 sperm entry(GO:0035037)
0.2 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 1.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.7 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2 0.5 GO:1904753 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.2 1.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.2 1.7 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.2 2.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.9 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 0.6 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.2 1.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.4 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.1 0.4 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 1.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.5 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.6 GO:0030202 heparin metabolic process(GO:0030202)
0.1 3.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 1.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 1.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 2.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 1.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 5.2 GO:0001706 endoderm formation(GO:0001706)
0.1 1.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.6 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.6 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.6 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.8 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.9 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.4 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 2.6 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.9 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 1.1 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.9 GO:0001842 neural fold formation(GO:0001842)
0.1 0.3 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.4 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.6 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.4 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 2.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.8 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 3.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 2.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.4 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.2 GO:1990428 miRNA transport(GO:1990428)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 2.0 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 1.9 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.4 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.8 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0097494 regulation of vesicle size(GO:0097494)
0.0 1.7 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.9 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 1.8 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.0 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.7 GO:0006907 pinocytosis(GO:0006907)
0.0 1.3 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 1.4 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 0.8 GO:0042026 protein refolding(GO:0042026)
0.0 0.4 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 1.8 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.7 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.4 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.9 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 1.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.1 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 2.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0035561 regulation of chromatin binding(GO:0035561)
0.0 0.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.7 2.0 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.5 1.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 2.1 GO:0097149 centralspindlin complex(GO:0097149)
0.3 0.9 GO:0090537 CERF complex(GO:0090537)
0.3 0.9 GO:1902560 GMP reductase complex(GO:1902560)
0.3 1.3 GO:0031251 PAN complex(GO:0031251)
0.2 0.7 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 2.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.2 GO:0070449 elongin complex(GO:0070449)
0.2 1.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.5 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.2 1.7 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.1 1.2 GO:0033503 HULC complex(GO:0033503)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.4 GO:0034679 integrin alpha9-beta1 complex(GO:0034679) integrin alphav-beta3 complex(GO:0034683)
0.1 0.8 GO:0097413 Lewy body(GO:0097413)
0.1 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.1 GO:0001940 male pronucleus(GO:0001940)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313) tubular endosome(GO:0097422)
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 3.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.6 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.3 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.5 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 3.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 3.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 6.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.4 GO:0005657 replication fork(GO:0005657)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 2.7 GO:0000776 kinetochore(GO:0000776)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.3 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.6 1.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 3.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.5 1.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.4 2.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 2.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 1.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 3.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 1.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 0.9 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3 4.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.9 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.7 GO:0031208 POZ domain binding(GO:0031208)
0.2 4.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 2.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 2.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 2.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.1 GO:0035198 miRNA binding(GO:0035198)
0.1 0.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 1.0 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 3.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.5 GO:0035197 siRNA binding(GO:0035197)
0.1 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0070051 fibrinogen binding(GO:0070051)
0.1 1.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 1.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.8 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 3.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 2.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 2.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 2.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.6 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 1.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 3.3 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 5.5 GO:0001047 core promoter binding(GO:0001047)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 2.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 2.4 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 9.8 GO:0044212 transcription regulatory region DNA binding(GO:0044212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 4.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 3.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 2.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 4.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 3.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 3.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 3.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis